Synthesis and anticonvulsant activity of a new class of 2- [(arylalkyl)amino]alkanamide derivatives

Journal of Medicinal Chemistry

Volumn 41, Issue 4, 1998, Pages 579-590

  Pevarello, Paolo ^a   Bonsignori, Alberto ^a   Dostert, Philippe ^c   Heidempergher, Franco ^a   Pinciroli, Vittorio ^a   Colombo, Maristella ^a   McArthur, Robert A ^a   Salvati, Patricia ^a   Post, Claes ^a   Fariello, Ruggero G ^b   Varasi, Mario ^a  

^a PFIZER INC   (United States)

^b Pharmacokinetics and Metabolism   (Italy)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[4 (3 CHLOROBENZOXY)BENZYL]AMINO]ACETAMIDE; ANTICONVULSIVE AGENT; BICUCULLINE; MILACEMIDE; SAFINAMIDE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ANTICONVULSANT THERAPY; ARTICLE; DRUG EFFICACY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; EPILEPSY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NEUROPHARMACOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; STRUCTURE ACTIVITY RELATION;

ALANINE; ANIMALS; ANTICONVULSANTS; BENZYLAMINES; BICUCULLINE; DRUG DESIGN; ELECTROSHOCK; INDICATORS AND REAGENTS; MALE; MICE; MICE, INBRED ICR; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOTOR ACTIVITY; MUSCULOSKELETAL EQUILIBRIUM; PICROTOXIN; RATS; RATS, INBRED STRAINS; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP; STRYCHNINE;

EID: 15144352587     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970599m     Document Type: Article

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