S-adenosylhomocysteine treatment of adult female fibroblasts alters X-chromosome inactivation and improves in vitro embryo development after somatic cell nuclear transfer

Reproduction

Volumn 135, Issue 6, 2008, Pages 815-828

  Jeon, Byeong Gyun ^a   Coppola, Gianfranco ^a   Perrault, Steven D ^a   Rho, Gyu Jin ^b   Betts, Dean H ^a   King, W Allan ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b Gyeongsang National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME PROTEIN; HISTONE H3; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LYSINE; METHYL CPG BINDING PROTEIN 2; PROTEIN ANT3; S ADENOSYLHOMOCYSTEINE; TELOMERASE; X INACTIVE SPECIFIC TRANSCRIPT PROTEIN; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; ARTICLE; BLASTOCYST; CELL NUCLEUS TRANSPLANTATION; CONTROLLED STUDY; COW; DNA METHYLATION; DNA REPLICATION TIMING; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; FEMALE; FIBROBLAST; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOMATIC CELL; SOMATIC CELL GENETICS; X CHROMOSOME; X CHROMOSOME INACTIVATION;

5-METHYLCYTOSINE; ANIMALS; CATTLE; DNA METHYLATION; EMBRYONIC DEVELOPMENT; FEMALE; FIBROBLASTS; HISTONES; METAPHASE; MICROSCOPY, FLUORESCENCE; NUCLEAR REPROGRAMMING; NUCLEAR TRANSFER TECHNIQUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; S-ADENOSYLHOMOCYSTEINE; TELOMERASE; TRANSCRIPTION, GENETIC; X CHROMOSOME INACTIVATION;

BOVINAE;

EID: 45249119748     PISSN: 14701626     EISSN: None     Source Type: Journal    
DOI: 10.1530/REP-07-0442     Document Type: Article

References (79)

1. Avner P & Heard E 2001 X-chromosome inactivation: Counting, choice and initiation. Nature Reviews. Genetics 2 59-67.
2. Bechter OE, Eisterer W, Dlaska M, Kuhr T & Thaler J 2002 CpG island methylation of the hTERT promoter is associated with lower telomerase activity in B-cell lymphocytic leukemia. Experimental Hematology 30 26-33.
3. Belyaev N, Keohane AM & Turner BM 1996 Differential underacetylation of histories H2A, H3 and H4 on the inactive X chromosome in human female cells. Human Genetics 97 573-578.
4. Di Berardino D, Coppola G, Verdoliva C, Coppola GF, Ramunno L, Enne G, Di Meo GP & Iannuzzi L 2002 Onset and sequence of RBA-band replication on the inactive X-chromosomes of cattle (Bos taurus L.), river buffalo (Bubalus bubalis L.) and goat (Capra hircus L). Chromosome Research 10 637-643.
5. Betts DH & King WA 1999 Telomerase activity and telomere detection during early bovine development. Developmental Genetics 25 397-403.
6. Betts D, Bordignon V, Hill J, Winger Q, Westhusin M, Smith L & King W 2001 Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle. PNAS 98 1077-1082.
7. Betts DH, Perrault S, Harrington L & King WA 2006 Quantitative analysis of telomerase activity and telomere length in domestic animal clones. Methods in Molecular Biology 325 149-180.
8. Bickmore WA & Carothers AD 1995 Factors affecting the timing and imprinting of replication on a mammalian chromosome. Journal of Cell Science 108 2801-2809.
9. Bird A 2002 DNA methylation patterns and epigenetic memory. Genes and Development 16 6-21.
10. Blasco MA 2003 Mammalian telomeres and telomerase: Why they matter for cancer and aging. European Journal of Cell Biology 82 441-446.
11. Boggs BA & Chinault AC 1994 Analysis of replication timing properties of human X-chromosomal loci by fluorescence in situ hybridization. PNAS 91 6083-6087.
12. Bourc'his D, Le Bourhis D, Patin D, Niveleau A, Comizzoli P, Renard JP & Viegas-Pequignot E 2001 Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos. Current Biology 11 1542-1546.
13. Brockdorff N 2002 X-chromosome inactivation: Closing in on proteins that bind Xist RNA. Trends in Genetics 18 352-358.
14. Brown CJ & Chow JC 2003 Beyond sense: The role of antisense RNA in controlling Xist expression. Seminars in Cell and Developmental Biology 14 341-347.
15. De Cabo SF, Hazen MJ, Molero ML & Fernandez-Piqueras J 1994 S-adenosyl-L-homocysteine: A non-cytotoxic hypomethylating agent. Experientia 50 658-659.
16. Carrel L, Hunt PA & Willard HF 1996 Tissue and lineage-specific variation in inactive X chromosome expression of the murine Smcx gene. Human Molecular Genetics 5 1361-1366.
17. Castilho A, Neves N, Rufini-Castiglione M, Viegas W & Heslop-Harrison JS 1999 5-Methylcytosine distribution and genome organization in triticale before and after treatment with 5-azacytidine. Journal of Cell Science 112 4397-4404.
18. Castro R, Rivera I, Martins C, Struys EA, Jansen EE, Clode N, Graca LM, Blom HJ, Jakobs C & de Almeida IT 2005 Intracellular S -adenosylhomocysteine increased levels are associated with DNA hypomethylation in HUVEC. Journal of Molecular Medicine 83 831-836.
19. Caudill MA, Wang JC, Melnyk S, Pogribny IP, Jernigan S, Collins MD, Santos-Guzman J, Swendseid ME, Cogger EA & James SJ 2001 intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice. Journal of Nutrition 131 2811-2818.
20. Chadwick BP & Willard HF 2004 Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome. PNAS 101 17450-17455.
21. Chang SC, Tucker T, Thorogood NP & Brown CJ 2006 Mechanisms of X-chromosome inactivation. Frontiers in Bioscience 11 852-866.
22. Christman JK 2002 5-Azacytidine and 5-aza-2-′-deoxycytidine as inhibitors of DNA methylation: Mechanistic studies and their implications for cancer therapy. Oncogene 21 5483-5495.
23. Cong YS, Wen J & Bacchetti S 1999 The human telomerase catalytic subunit hTERT: Organization of the gene and characterization of the promoter. Human Molecular Genetics 8 137-142.
24. Csankovszki G, Nagy A & Jaenisch R 2001 Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. Journal of Cell Biology 153 773-784.
25. Dean W, Santos F, Stojkovic M, Zakhartchenko V, Walter J, Wolf E & Reik W 2001 Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos. PNAS 98 13734-13738.
26. De La Fuente R. Hahnel A, Basrur PK & King WA 1999 X inactive-specific transcript (Xist) expression and X chromosome inactivation in the preattachment bovine embryo. Biology of Reproduction 60 769-775.
27. Dessain SK, Yu H, Reddel RR, Beijersbergen RL & Weinberg RA 2000 Methylation of the human telomerase gene CpG island. Cancer Research 60 537-541.
28. Enright BP, Kubota C, Yang X & Tian XC 2003 Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2′-deoxycytidine. Biology of Reproduction 69 896-901.
29. Enright BP, Sung LY, Chang CC, Yang X & Tian XC 2005 Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2′-deoxycytidine. Biology of Reproduction 72 944-948.
30. Fahrner JA, Eguchi S, Herman JG & Baylin SB 2002 Dependence of histone modifications and gene expression on DNA hypermethylation in cancer. Cancer Research 62 7213-7218.
31. Garcia-Cao M, O'Sullivan R, Peters AH, Jenuwein T & Blasco MA 2004 Epigenetic regulation of telomere length in mammalian cells by the SUV39H1 and SUV39H2 histone methyltransferases. Nature Genetics 36 94-99.
32. Gonzalo S, Jaco J, Fraga MF, Chen T, Li E, Esteller M & Blasco MA 2006 DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nature Cell Biology 8 416-424.
33. Greider CW 1998 Teiomerase activity, cell proliferation and cancer. PNAS 95 90-92.
34. Guilleret I & Benhattar J 2003 Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and velomerase activity and shortened telomeres. Experimental Cell Research 289 326-334.
35. Haaf T, Ott G & Schmid M 1988 Inhibition of condensation in the late-replicating X chromosome induced by 5-azadeoxycytidine in human lymphocyte cultures. Human Genetics 79 18-23.
36. Han YM, Kang YK, Koo DB & Lee KK 2003 Nuclear reprogramming of cloned embryos produced in vitro. Theriogenology 59 33-44.
37. Hansen RS, Canfield TK, Fjeld AD & Gartler SM 1996 Role of late replication timing in the silencing silencing of X-linked genes. Human Molecular Genetics 5 1345-1353.
38. Heard E 2004 Recent advances in X-chromosome inactivation. Current Opinion in Cell Biology 16 247-255.
39. Herath CB, Ishiwata H, Shiojima S, Kadowaki T, Katsuma S, Ushizawa K, Imai K, Takahashi T, Hirasawa A, Takahashi S et al. 2006 Developmental aberrations of liver gene expression in bovine fetuses derived from somatic cell nuclear transplantation. Cloning and Stem Cells 8 79-95.
40. Hermes M, Osswald H, Mattar J & Kloor D 2004 influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells. Experimental Cell Research 294 325-334.
41. Izbicka E, Nishioka D, Marcell V, Raymond E, Davidson KK, Lawrence RA, Wheelhouse RT, Hurley LH, Wu RS & Von Hoff DD 1999 Telomere-interactive agents affect proliferation rates and induce chromosomal destabilization in sea urchin embryos. Anti-Cancer Drug Design 14 355-365.
42. Jablonka, E, Goitein R, Sperling K, Cedar H & Marcus M 1987 5-aza-C-induced changes in the time of replication of the X chromosomes of Microtus agrestis are followed by non-random reversion to a late pattern of replication. Chromosoma 95 81-88.
43. Kang YK, Koo DB, Park JS, Choi YH, Chung AS, Lee KK & Han YM 2001 Aberrant methylation of donor genome in cloned bovine embryos. Nature Genetics 28 173-177.
44. Keohane AM, Barlow AL, Waters J, Bourn D & Turner BM 1999 H4 acetylation, XIST RNA and replication timing are coincident and define x;autosome boundaries in two abnormal X chromosomes. Human Molecular Genetics 8 377-383.
45. Kim KC, Geng L & Huang S 2003 Inactivation of a histone methyltransferase by mutations in human cancers. Cancer Research 63 7619-7623.
46. Lanza RP, Cibelli JB, Blackwell C, Cristofalo VJ, Francis MK, Baerlocher GM, Mak J, Schertzer M, Chavez EA, Sawyer N, Lansdorop PM & West MD 2000 Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 288 665-669.
47. Lee HS, Park MH, Yang SJ, Jung HY, Byun SS, Lee DS, Yoo HS, Yeom YI & Seo SB 2004 Gene expression analysis in human gastric cancer cell line treated with trichostatin A and S-adenosyl-L-homocysteine using cDNA microarray. Biological & Pharmaceutical Bulletin 27 1497-1503.
48. Lehnertz B, Ueda Y, Derijck AA, Braunschweig U, Perez-Burgos L, Kubicek S, Chen T, Li E, Jenuwein T & Peters AH 2003 Suv39h-rnediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Current Biology 13 1192-1200.
49. Li X, Amarnath D, Kato Y & Tsunoda Y 2006 Analysis of development-related gene expression in cloned bovine blastocysts with different developmental potential. Cloning and Stem Cells 8 41-50.
50. Liang G, Gonzales FA, Jones PA, Omtoft TF & Thykjaer T 2002 Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2-deoxycytidine. Cancer Research 62 961-966.
51. Luo S, Torchia BS & Migeon BR 1995 XIST expression is re-pressed when X inactivation is reversed in human placental cells: A model for study of XIST regulation. Somatic Cell and Molecular Genetics 21 51-60.
52. Mastromonaco GF, Semple E, Robert C, Rho GJ, Betts DH & King WA 2004 Different culture media requirements of IVF and nuclear transfer bovine embryos. Reproduction in Domestic Animals 39 462-467.
53. Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA et al. 2003 Telomerase maintains telomere structure in normal human cells. Cell 114 241-253.
54. Mathieu O, Probst AV & Paszkowski J 2005 Distinct regulation of histone H3 methylation at lysines 27 and 9 by CpG methylation in Arabidopsis. EMBO Journal 24 2783-2791.
55. Mohana Kumar B, Jin HF, Kim JG, Song HJ, Hong Y, Balasubramanian S, Choe SY & Rho GJ 2006 DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine. Cell and Tissue Research 325 44S-454.
56. Morgan HD, Santos F, Green K, Dean W & Reik W 2005 Epigenetic reprogramming in mammals. Human Molecular Genetics 1 R47-R58.
57. Mostoslavsky R, Singh N, Tenzen T, Goldmit M, Gabay C, Elizur S, Qi P, Reubinoff BE, Chess A, Cedar H et al. 2001 Asynchronous replication and allelic exclusion in the immune system. Nature 414 221-225.
58. Nieto M, Samper E, Fraga MF, Gonzalez de Buitrago G, Esteller M & Serrano M 2004 The absence of p53 is critical for the induction of apoptosis by 5-aza-2′-deoxycytidine. Oncogene 23 735-743.
59. Nino-Soto MI, Nuber UA, Basrur PK, Ropers HH & King WA 2005 Differences in the pattern of X-linked gene expression between fetal bovine muscle and fibroblast cultures derived from the same muscle biopsies. Cytogenetic and Genome Research 111 57-64.
60. Nolen LD, Gao S, Han Z, Mann MR, Gie Chung Y, Otte AP, Bartolomei MS & Latham KE 2005 X chromosome reactivation and regulation in cloned embryos. Developmental Biology 279 525-540.
61. Perrault SD, Hornsby PJ & Betts DH 2005 Global gene expression response to telomerase in bovine adrenocortical cells. Biochemical and Biophysical Research Communications 335 925-936.
62. Peters AH, Mermoud JE, O'Carroll D, Pagani M, Schweizer D, Brockdorff N & Jenuwein T 2002 Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin. Nature Genetics 30 77-80.
63. Peters AH, Kubicek S, Mechtler K, O'Sullivan RJ, Derijck AA, Perez-Burgos L, KohImaier A, Opravil S, Tachibana M, Shinkai Y et al. 2003 Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Molecular Cell 12 1577-1589.
64. Plath K, Fang J, Mlynarczyk-Evans SK, Cao R, Worringer KA, Wang H, de la Cruz CC, Otte AP, Panning B & Zhang Y 2003 Role of histone H3 lysine 27 methylation in X inactivation. Science 300 131-135.
65. Ponce de Leon FA, Li Y & Weng Z 1992 Early and late replicative chromosomal banding patterns of Gallus domesticus. Journal of Heredity 83 36-42.
66. Reik W, Dean W & Walter J 2001 Epigenetic reprogramming in mammalian development. Science 293 1089-1093.
67. Renaud S, Loukinov D, Abdullaev Z, Guilleret I, Bosman FT, Lobanenkov V & Benhattar J 2007 Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. Nucleic Acids Research 35 1245-1256.
68. Santos F, Zakhartchenko V, Stojkovic M, Peters A, Jenuwein T, Wolf E, Reik W & Dean W 2003 Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Current Biology 13 1116-1121.
69. Sasaki T, Hansen RS & Gartler SM 1992 Hemimethylation and hypersensitivity are early events in transcriptional reactivation of human inactive X-linked genes in a hamster x human somatic cell hybrid. Molecular Cell Biology 12 3819-3826.
70. Shi W, Hoeflich A, Flaswinkel H, Stojkovic M, Wolf E & Zakhartchenko V 2003 Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos. Biology of Reproduction 69 301-309.
71. Shin KH, Kang MK, Dicterow E & Park NH 2003 Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent oral keratinocytes. British Journal of Cancer 89 1473-1478.
72. Tamaru H & Selker EU 2001 Histone H3 methyltransferase controls DNA methylation in Neurospora crassa. Nature 414 277-283.
73. Thouas GA, Korfiatis NA, French AJ, Jones GM & Trounson AO 2001 Simplified technique for differentia staining of inner cell mass and trophectoderm cells of mouse and bovine blastocysts. Reproductive Biomedicine Online 3 25-29.
74. Tinker AV & Brown CJ 1998 Induction of XIST expression from the human active X chromosome in mouse/human somatic cell hybrids by DNA demethylation. Nucleic Acids Research 26 2935-2940.
75. Vajta G 2007 Somatic cell nuclear transfer in its first and second decades: Successes, setbacks, paradoxes and perspectives. Reproductive Biomedicine Online 15 582-590.
76. Wrenzycki C, Lucas-Hahn A, Herrmann D, Lemme E, Korsawe K & Niemann H 2002 In vitro production and nuclear transfer affect dosage compensation of the X-linked gene transcripts G6PD, PGK, and Xist in preimplantation bovine embryos. Biology of Reproduction 66 427-134.
77. Xue F, Tian XC, Du F, Kubota C, Taneja M, Dinnyes A, Dai Y, Levine H, Pereira LV & Yang X 2002 Aberrant patterns of X chromosome inactivation in bovine clones. Nature Genetics 31 216-220.
78. Yamada O, Takanashi M, Ujihara M & Mizoguchi H 1998 Down-regulation of telomerase activity is an early event of cellular differentiation without apparent telomeric DNA change. Leukemia Research 22 711-717.
79. Yi P, Melnyk S, Pogribna M, Pogribny IP, Hine RJ & James SJ 2000 Increase in plasma homocysteine associated with parallel increases in plasma S-adenosylhomocysteine and lymphocyte DNA hypomethylation. Journal of Biological Chemistry 275 29318-29323.