-
1
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W., and Weinberg, R. A. Creation of human tumour cells with defined genetic elements. Nature (Lond.), 400: 464-468, 1999.
-
(1999)
Nature (Lond.)
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
2
-
-
0000146723
-
Short dysfunctional telomeres impair tumorigenesis in the INK4a(Δ2/3) cancer-prone mouse
-
Greenberg, R. A., Chin, L., Femino, A., Lee, K. H., Gottlieb, G. J., Singer, R. H., Greider, C. W., and DePinho, R. A. Short dysfunctional telomeres impair tumorigenesis in the INK4a(Δ2/3) cancer-prone mouse. Cell, 97: 515-525, 1999.
-
(1999)
Cell
, vol.97
, pp. 515-525
-
-
Greenberg, R.A.1
Chin, L.2
Femino, A.3
Lee, K.H.4
Gottlieb, G.J.5
Singer, R.H.6
Greider, C.W.7
DePinho, R.A.8
-
3
-
-
0031010342
-
A survey of telomerase activity in human cancer
-
Shay, J. W., and Bacchetti, S. A survey of telomerase activity in human cancer, Eur. J. Cancer, 33: 787-791, 1997.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 787-791
-
-
Shay, J.W.1
Bacchetti, S.2
-
4
-
-
0032485416
-
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase
-
Counter, C. M., Meyerson, M., Eaton, E. N., Ellisen, L. W., Caddle, S. D., Haber, D. A., and Weinberg, R. A. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene, 16: 1217-1222, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 1217-1222
-
-
Counter, C.M.1
Meyerson, M.2
Eaton, E.N.3
Ellisen, L.W.4
Caddle, S.D.5
Haber, D.A.6
Weinberg, R.A.7
-
5
-
-
0030659644
-
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT
-
Weinrich, S. L., Pruzan, R., Ma, L., Ouellette, M., Tesmer, V. M., Holt, S. E., Bodnar, A. G., Lichtsteiner, S., Kim, N. W., Trager, J. B., Taylor, R. D., Carlos, R., Andrews, W. H., Wright, W. E., Shay, J. W., Harley, C. B., and Morin, G. B. Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat. Genet., 17: 498-502, 1997.
-
(1997)
Nat. Genet.
, vol.17
, pp. 498-502
-
-
Weinrich, S.L.1
Pruzan, R.2
Ma, L.3
Ouellette, M.4
Tesmer, V.M.5
Holt, S.E.6
Bodnar, A.G.7
Lichtsteiner, S.8
Kim, N.W.9
Trager, J.B.10
Taylor, R.D.11
Carlos, R.12
Andrews, W.H.13
Wright, W.E.14
Shay, J.W.15
Harley, C.B.16
Morin, G.B.17
-
6
-
-
0033558281
-
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
-
Horikawa, I., Cable, P. L., Afshari, C., and Barrett, J. C. Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res., 59: 826-830, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 826-830
-
-
Horikawa, I.1
Cable, P.L.2
Afshari, C.3
Barrett, J.C.4
-
7
-
-
0032962953
-
The human telomerase catalytic subunit hTERT: Organization of the gene and characterization of the promoter
-
Cong, Y. S., Wen, J., and Bacchetti, S. The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter [In Process Citation]. Hum. Mol. Genet., 8: 137-142, 1999.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 137-142
-
-
Cong, Y.S.1
Wen, J.2
Bacchetti, S.3
-
8
-
-
0033082526
-
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
-
Takakura, M., Kyo, S., Kanaya, T., Hirano, H., Takeda, J., Yutsudo, M., and Inoue, M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res., 59: 551-557, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 551-557
-
-
Takakura, M.1
Kyo, S.2
Kanaya, T.3
Hirano, H.4
Takeda, J.5
Yutsudo, M.6
Inoue, M.7
-
9
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones, P. A., and Laird, P. W. Cancer epigenetics comes of age. Nat. Genet., 21: 163-167, 1999.
-
(1999)
Nat. Genet.
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
10
-
-
0030459140
-
The role of DNA methylation in cancer genetic and epigenetics
-
Laird, P. W., and Jaenisch, R. The role of DNA methylation in cancer genetic and epigenetics. Annu. Rev. Genet., 30: 441-464, 1996.
-
(1996)
Annu. Rev. Genet.
, vol.30
, pp. 441-464
-
-
Laird, P.W.1
Jaenisch, R.2
-
11
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin, S. B., Herman, J. G., Graff, J. R., Vertino, P. M., and Issa, J. P. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res., 72: 141-196, 1998.
-
(1998)
Adv. Cancer Res.
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
12
-
-
0032401808
-
Aging, and DNA methylation in colorectal mucosa and cancer
-
Ahuja, N., Li, Q., Mohan, A. L., Baylin, S. B., and Issa, J. P. Aging, and DNA methylation in colorectal mucosa and cancer. Cancer Res., 58: 5489-5494, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 5489-5494
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.5
-
13
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota, M., Ahuja, N., Ohe-Toyota, M., Herman, J. G., Baylin, S. B., and Issa, J. P. CpG island methylator phenotype in colorectal cancer. Proc. Natl. Acad. Sci. USA, 96: 8681-8686, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
14
-
-
0025006860
-
High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines
-
Antequera, F., Boyes, J., and Bird, A. High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines. Cell, 62: 503-514, 1990.
-
(1990)
Cell
, vol.62
, pp. 503-514
-
-
Antequera, F.1
Boyes, J.2
Bird, A.3
-
15
-
-
13144307115
-
Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MS1 cancers
-
Veigl, M. L., Kasturi, L., Olechnowicz, J., Ma, A. H., Lutterbaugh, J. D., Periyasamy, S., Li, G. M., Drummond, J., Modrich, P. L., Sedwick, W. D., and Markowitz, S. D. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MS1 cancers. Proc. Natl. Acad. Sci. USA, 95: 8698-8702, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8698-8702
-
-
Veigl, M.L.1
Kasturi, L.2
Olechnowicz, J.3
Ma, A.H.4
Lutterbaugh, J.D.5
Periyasamy, S.6
Li, G.M.7
Drummond, J.8
Modrich, P.L.9
Sedwick, W.D.10
Markowitz, S.D.11
-
16
-
-
0029843950
-
Methylation-specific PCR, a novel PCR assay for methylation status of CpG islands
-
Herman, J. G., Graff, J. R., Myohanen, S., Nelkin, B. D., and Baylin, S. B. Methylation-specific PCR, a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. USA, 93: 9821-9826, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
17
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Washington DC
-
Nakamura, T. M., Morin, G. B., Chapman, K. B., Weinrich, S. L., Andrews, W. H., Lingner, J., Harley, C. B., and Cech, T. R. Telomerase catalytic subunit homologs from fission yeast and human. Science (Washington DC), 77: 955-959, 1997.
-
(1997)
Science
, vol.77
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
Weinrich, S.L.4
Andrews, W.H.5
Lingner, J.6
Harley, C.B.7
Cech, T.R.8
-
18
-
-
0027141519
-
Number of CpG islands and genes in human and mouse
-
Antequera, F., and Bird, A. Number of CpG islands and genes in human and mouse. Proc. Natl. Acad. Sci. USA, 90: 11995-11999, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11995-11999
-
-
Antequera, F.1
Bird, A.2
-
19
-
-
0019332015
-
Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues
-
Wang, R. Y., Gehrke, C. W., and Ehrlich, M. Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues. Nucleic Acids Res., 8: 4777-4790, 1980.
-
(1980)
Nucleic Acids Res.
, vol.8
, pp. 4777-4790
-
-
Wang, R.Y.1
Gehrke, C.W.2
Ehrlich, M.3
-
20
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan, T. M., Englezou, A., Dalla-Pozza, L., Dunham, M. A., and Reddel, R. R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med., 3: 1271-1274, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 1271-1274
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
21
-
-
0018860957
-
Cellular differentiation, cytidine analogs and DNA methylation
-
Jones, P. A., and Taylor, S. M. Cellular differentiation, cytidine analogs and DNA methylation. Cell, 20: 85-93, 1980.
-
(1980)
Cell
, vol.20
, pp. 85-93
-
-
Jones, P.A.1
Taylor, S.M.2
-
22
-
-
0030743347
-
Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
-
Kim, N. W., and Wu, F. Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). Nucleic Acids Res., 25: 2595-2597, 1997.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2595-2597
-
-
Kim, N.W.1
Wu, F.2
-
23
-
-
0033558192
-
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers
-
Bachman, K. E., Herman, J. G., Corn, P. G., Merlo, A., Costello, J. F., Cavenee, W. K., Baylin, S. B., and Graff, J. R. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res., 59: 798-802, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 798-802
-
-
Bachman, K.E.1
Herman, J.G.2
Corn, P.G.3
Merlo, A.4
Costello, J.F.5
Cavenee, W.K.6
Baylin, S.B.7
Graff, J.R.8
-
24
-
-
0031869107
-
Telomere length dynamics in telomerase-positive immortal human cell populations
-
Bryan, T. M., Englezou, A., Dunham, M. A., and Reddel, R. R. Telomere length dynamics in telomerase-positive immortal human cell populations. Exp. Cell Res., 239: 370-378, 1998.
-
(1998)
Exp. Cell Res.
, vol.239
, pp. 370-378
-
-
Bryan, T.M.1
Englezou, A.2
Dunham, M.A.3
Reddel, R.R.4
|