In Drosophila melanogaster the COM locus directs the somatic silencing of two retrotransposons through both Piwi-dependent and -independent pathways

PLoS ONE

Volumn 3, Issue 2, 2008, Pages

  Desset, Sophie ^a   Buchon, Nicolas ^b   Meignin, Carine ^c   Coiffet, Michael ^a   Vaury, Chantal ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b EPFL   (Switzerland)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; PIWI PROTEIN; SMALL INTERFERING RNA; DROSOPHILA PROTEIN; PIWI PROTEIN, DROSOPHILA; PROTEIN;

5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA MELANOGASTER; GENE LOCUS; GENE REPRESSION; GENE SILENCING; GENE TARGETING; INSECT DEVELOPMENT; LONG TERMINAL REPEAT; MOLECULAR RECOGNITION; NONHUMAN; OOCYTE; OVARY FOLLICLE CELL; RETROPOSON; SOMATIC CELL GENETICS; ANIMAL; FEMALE; GENETICS; METABOLISM; OVARY; PHYSIOLOGY; SIGNAL TRANSDUCTION; X CHROMOSOME;

DROSOPHILA MELANOGASTER;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE SILENCING; OVARY; PROTEINS; RETROELEMENTS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; X CHROMOSOME;

EID: 45249113294     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001526     Document Type: Article

References (32)

1. Kalmykova AI, Klenov MS, Gvozdev VA (2005) Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline. Nucleic Acids Res 33: 2052-2059.
2. Ketting RF, Haverkamp TH, van Luenen HG, Plasterk RH (1999) Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD. Cell 99: 133-141.
3. Sarot E, Payen-Groschene G, Bucheton A, Pelisson A (2004) Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene. Genetics 166: 1313-1321.
4. Bernstein E, Denli AM, Hannon GJ (2001) The rest is silence Rna 7:1509-1521.
5. Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, et al. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elcgans. Genes Dev 15: 2654-2659.
6. Lee YS, Nakahara Y, Pham JW, Kim K, He Z, et al. (2004) Distinct roles for Drosophila, Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117: 69-81.
7. Ambros V (2004) The functions of animal microRNAs. Nature 431: 350-355.
8. Du T, Zamore PD (2005) microPrimer: the biogenesis and function of microRNA. Development 132: 4645-4652.
9. Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, et al. (2007) Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila. Cell 128: 1089-1103.
10. Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, et al. (2007) A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science 315: 1587-1590.
11. Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, et al. (2006) A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442: 203-207.
12. Girard A, Sachidanandam R, Hannon GJ, Cannell MA (2006) A germline-specific class of small RNAs binds mammalian Piwi Proteins. Nature 442: 199-202.
13. Pélisson A, Sarot E, Payen-Groschene G, Bucheton A (2007) A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. J Virol 81: 1951-1960.
14. Saito K, Nishida KM, Mori T, Kawamura Y, Miyoshi K, et al. (2006) Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20: 2214-2222.
15. Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, et al. (2006) A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313: 320-324.
16. Desset S, Meignin C, Dastugue B, Vaury C (2003) COM, a heterochromatic locus governing the control of independent endogenous retroviruses from Drosophila melanogaster. Genetics 164: 501-509.
17. Desset S, Conte C, Dimitri P, Calco V, Dastugue B, et al. (1999) Mobilization of two retroelements, ZAM and Idefix, in a novel unstable line of Drosophila melanogaster. Mol Biol Evol 16: 54-66.
18. Leblanc P, Desset S, Giorgi F, Taddei AR, Fausto AM, et al. (2000) Life cycle of an endogenous retrovirus, ZAM, in Drosophila melanogaster. J Virol 74: 10658-10669.
19. Meignin C, Dastugue B, Vaury C (2004) Intercellular communication between germ line and somatic line is utilized to control the transcription of ZAM, an endogenous retrovirus from Drosophila melanogaster. Nucleic Acids Res 32: 3799-3806.
20. Ahmad K, Golic KG (1996) Somatic reversion of chromosomal position effects in Drosophila melanogaster. Genetics 144: 657-670.
21. Aravin AA, Naumova NM, Tulin AV, Vagin VV, Rozovsky YM, et al. (2001) Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline. Curr Biol 11: 1017-1027.
22. Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
23. Grimaud C, Bantignies F, Pal-Bhadra M, Ghana P, Bhadra U, et al. (2006) RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124: 957-971.
24. Pal-Bhadra M, Bhadra U, Birchler JA (2002) RNAi related mechanisms affect both transcriptional and postranscriptional transgene silencing in Drosophila. Mol Cell 9: 315-327.
25. Pal-Bhadra M, Leibovitch BA, Gandhi SG, Rao M, Bhadra U, et al. (2004) Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303: 669-672.
26. Yin H, Lin H (2007) An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature 450: 304-308.
27. Aravin AA, Klenov MS, Vagin VV, Bantignies F, Cavalli G, et. al. (2004) Dissection of a natural RNA silencing process in the Drosophila melanogaster germ line. Mol Cell Biol 24: 6742-6750.
28. Biemont C, Vieira C (2006) Genetics: junk DNA as an evolutionary force. Nature 443: 521-524.
29. Williams RW, Rubin GM (2002) ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc Natl Acad Sci U S A 99: 6889-6894.
30. Pal-Bhadra M, Bhadra U, Birchler JA (2004) Interrelationship of RNA interference and transcriptional gene silencing in Drosophila. Cold Spring Harb Symp Quant Biol 69: 433-438.
31. Robert V, Prud'homme N, Kim A, Bucheton A, Pelisson A (2001) Characterization of the flamenco region of the Drosophila melanogaster genome. Genetics 158: 701-713.
32. Leblanc P, Desset S, Dastugue B, Vaury C (1997) Invertebrate retroviruses: ZAM a new candidate in D.melanogaster. Embo J 16: 7521-7531.