Identification of drosophila mutants altering defense of and endurance to Listeria monocytogenes infection

Genetics

Volumn 178, Issue 3, 2008, Pages 1807-1815

  Ayres, Janelle S ^a   Freitag, Nancy ^b   Schneider, David S ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; CELL LINE; CELL STRAIN S2; DEFENSE MECHANISM; DISEASE PREDISPOSITION; DROSOPHILA; ENDURANCE; FLY; GENE IDENTIFICATION; IMMUNE RESPONSE; IN VITRO STUDY; LIFE CYCLE; LISTERIA MONOCYTOGENES; LISTERIOSIS; MUTANT; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL; ANIMAL; DROSOPHILA MELANOGASTER; GENE; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; MICROBIOLOGY; PHYSIOLOGY; RNA PROCESSING; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; UBIQUITINATION;

ANIMALIA; BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES;

ANIMALS; DROSOPHILA MELANOGASTER; GENES, INSECT; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MUTATION; PHENOTYPE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA-BINDING PROTEINS; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; SURVIVAL ANALYSIS; UBIQUITINATION;

EID: 45149096655     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.107.083782     Document Type: Article

References (46)

1. AGAISSE, H., L. S. BURRACK, J. PHILIPS, E. J. RUBIN, N. PERRIMON et al., 2005 Genome wide RNAi screen for host factors required for intracellular bacterial infection. Science 309: 1248-1251.
2. ALI, S., A. M. VOLLAARD, S. WIDJAJA, C. SURJADI, E. VAN DE VOSSE et al., 2006 PARK2/PACRG polymorphisms and susceptibility to typhoid and paratyphoid fever. Clin. Exp. Immunol. 144: 425-431.
3. AYRES, J. S., and D. S. SCHNEIDER, 2006 Genomic dissection of microbial pathogenesis in cultured Drosophila cells. Trends Microbiol. 14: 101-104.
4. BOUTROS, M., H. AGAISSE and N. PERRIMON, 2002 Sequential activation of signaling pathways during innate immune responses in Drosophila. Dev. Cell 3: 711-722.
5. CHENG, L. W., J. P. VIALA, N. STUURMAN, U. WIEDERMANN, R. D. VALE et al., 2005 Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen. Proc. Natl. Acad. Sci. USA 102: 13646-13651.
6. COSSART, P., and M. LECUIT, 1998 Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling. EMBO J. 17: 3797-3806.
7. COSSART, P., J. PIZARRO-CERDA and M. LECUIT, 2003 Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions. Trends Cell Biol. 13: 23-31.
8. DEGREGORIO, E., P. T. SPELLMAN, P. TZOU, G. M. RUBIN and B. LEMAITRE, 2002 The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J. 21: 2568-2579.
9. DOMANN, E., J. WEHLAND, M. ROHDE, S. PISTOR, M. HARTL et al., 1992 A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin. EMBO J. 11: 1981-1990.
10. FOLEY, E., and P. H. O'FARRELL, 2004 Functional dissection of an innate immune response by a genome-wide RNAi screen. PLoS Biol. 2: E203.
11. GEDDE, M. M., D. E. HIGGINS, T. G. TILNEY and D. A. PORTNOY, 2000 Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes. Infect. Immun. 68: 999-1003.
12. GESELLCHEN, V., D. KUTTENKEULER, M. STECKEL, N. PELTE and M. BOUTROS, 2005 An RNA interference screen identifies Inhibitor of Apoptosis Protein 2 as a regulator of innate immune signaling in Drosophila. EMBO Rep. 6: 979-984.
13. KAMBRIS, Z., S. BRUN, I. H. JANG, H. J. NAM, Y. ROMEO et al., 2006 Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for Toll activation. Curr. Biol. 16: 808-813.
14. KHUSH, R. S., F. LEULIER and B. LEMAITRE, 2001 Drosophila immunity: two paths to NF-kappaB. Trends Immunol. 22: 260-264.
15. KHUSH, R. S., W. D. CORNWELL, J. N. URAM and B. LEMAITRE, 2002 Ubiquitin-proteosome pathway represses the Drosophila immune deficiency signaling cascade. Curr. Biol. 12: 1728-1737.
16. KOCKS, C., E. GOUIN, M. TABOURET, P. BERCHE, H. OHAYON et al., 1992 Listeria monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 68: 521-531.
17. KOCKS, C., R. HELLIO, P. GOUNON, H. OHAYON and P. COSSART, 1993 Polarized distribution of Listeria monocytogenes surface protein ActA at the site of directional actin assembly. J. Cell Sci. 105: 699-710.
18. KOPP, E. B., and R. MEDZHITOV, 1999 The Toll-receptor family and control of innate immunity. Curr. Opin. Immunol. 11: 13-18.
19. KOPP, E. B., and R. MEDZHITOV, 2003 Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 15: 396-401.
20. KREFT, J., and J. A. VAZQUEZ-BOLAND, 2001 Regulation of virulence genes in Listeria. Int. J. Med. Microbiol. 291: 145-157.
21. KUHN, M., S. KATHARIOU and W. GOEBEL, 1988 Hemolysin Supports survival but not entry of the intracellular bacterium Listeria monocytogenes. Infect. Immun. 56: 79-82.
22. LECUIT, M., S. DRAMSI, C. GOTTARDI, M. FEDOR-CHAIKEN, B. GUMBINER et al., 1999 A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes. EMBO J. 18: 3956-3963.
23. LECUIT, M., S. VANDORMAEL-POURNIN, J. LEFORT, M. HUERRE, P. GOUNON et al., 2001 A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 292: 1722-1725.
24. LEMAITRE, B., M. MEISTER, S. GOVIND, P. GEORGEL, R. STEWARD et al., 1995 Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J. 14: 536-545.
25. LEMAITRE, B., E. NICOLAS, L. MICHAUT, J. M. REICHART and J. A. HOFFMANN, 1996 The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983.
26. LEMAITRE, B., J. M. REICHART and J. A. HOFFMANN, 1997 Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc. Natl. Acad. Sci. USA 94: 14614-14619.
27. LEULIER, F., A. RODRIGUEZ, R. S. KHUSH, J. M. ABRAMS and B. LEMAITRE, 2000 The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. EMBO Rep. 1: 353-358.
28. LORENZETTI, D., B. ANTALFFY, H. VOGEL, J. NOVEROSKE, D. ARMSTRONG et al., 2004 The neurological mutant quaking(viable) is parkin deficient. Mamm. Genome 15: 210-217.
29. MANSFIELD, B. E., M. S. DIONNE, D. S. SCHNEIDER and N. E. FREITAG, 2003 Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cell Microbiol. 5: 901-911.
30. MENG, X., B. S. KHANUJA and Y. T. IP, 1999 Toll receptor-mediated Drosophila immune response required Dif, an NF-kappaB factor. Genes Dev. 13: 792-797.
31. MICHEL, T., J. M. REICHART, J. A. HOFFMANN and J. ROYET, 2001 Drosophila Toll is activated by gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 414: 756-759.
32. MILCHANOWSKI, A. B., A. L. HENKENIUS, M. NARAYANAN, V. HARTENSTEIN and U. BANERJEE, 2004 Identification and characterization of genes involved in embryonic crystal cell formation during Drosophila hematopoiesis. Genetics 168: 325-339.
33. O'RIORDAN, M., and D. A. PORTNOY, 2002 The host cytosol: frontline or home front. Trends Microbiol. 10: 361-364.
34. PARK, J. M., H. BRADY, M. G. RUOCCO, H. SUN, D. WILLIAMS et al., 2004 Targeting of TAK1 by the NF-kappa B protein Relish regulates the JNK-mediated immune response in Drsophila. Genes Dev. 18: 584-594.
35. PORTNOY, D. A., P. S. JACKS and D. J. HINRICHS, 1988 Role of haemolysin for the intracellular growth of Listeria monocytogenes. J. Exp. Med. 167: 1459-1471.
36. RAMET, M., P. MANFRUELLI, A. PEARSON, B. MATHEY-PREVOT and R. A. EZEKOWITZ, 2002 Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416: 644-648.
37. RUTSCHMANN, S., A. C. JUNG, R. ZHOU, N. SILVERMANN, J. A. HOFFMANN et al., 2000 Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nat. Immunol. 1: 342-347.
38. RUTSCHMANN, S., A. KILINC and D. FERRANDON, 2002 Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila. J. Immunol. 168: 1542-1546.
39. SCHURR, E., A. ALCAIS, L. DE LESELEUC and L. ABEL, 2006 Genetic predisposition to leprosy: a major gene reveals novel pathways of immunity to Mycobacterium leprae. Semin. Immunol. 6: 404-410.
40. TAUSZIG-DELAMASURE, S., H. BILAK, M. CAPOVILLA, J. A HOFFMANN and J. IMLER, 2002 Drosophila MyD88 is required for the response to fungal and gram-positive bacterial infections. Nat. Immunol. 3: 91-97.
41. TILNEY, L. G., and D. A. PORTNOY, 1989 Actin filaments and the growth, movement and spread of the intracellular bacterial parasite, Listeria monocytogenes. J. Cell Biol. 109: 1597-1608.
42. TILNEY, L. G., P. S. CONNELLY and D. A. PORTNOY, 1990 Actin filament nucleation by the bacterial pathogen, Listeria monocytogenes. J. Cell Biol. 111: 2979-2988.
43. VAZQUEZ-BOLAND, J. A., M. KUHN, P. BERCHE, T. CHAKRABORTY, G. DOMINGUEZ-BERNAL et al., 2001 Listeria pathogenesis and molecular virulence determinants. Clin. Microbiol. Rev. 14: 584-640.
44. WU, L. P., K. M. CHOE, Y. LU and K. V. ANDERSON, 2001 Drosophila immunity: genes on the third chromosome required for the response to bacterial infection. Genetics 159: 189-199.
45. YAGI, Y., and Y. T. IP, 2005 Helicase89B is a Mot1/BTAF1 homologue that mediates an antimicrobial response in Drosophila. EMBO Rep. 6: 1088-1094.
46. ZHOU, R., N. SILVERMANN, M. HONG, D. S. LIAO, Y. CHUNG et al., 2005 The role of ubiquitination in Drosophila innate immunity. J. Biol. Chem. 40: 34048-34055.