Regulation of virulence genes in Listeria

International journal of medical microbiology : IJMM

Volumn 291, Issue 2, 2001, Pages 145-157

  Kreft, Jürgen ^a   Vázquez Boland, José A ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHAPERONE; PEPTIDE CHAIN TERMINATION RELEASE FACTOR 1; PEPTIDE CHAIN-TERMINATION RELEASE FACTOR 1; TRANSACTIVATOR PROTEIN; TRANSLATION TERMINATION FACTOR;

GENE EXPRESSION REGULATION; GENETICS; LISTERIA MONOCYTOGENES; PATHOGENICITY; REVIEW; VIRULENCE;

BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; LISTERIA MONOCYTOGENES; MOLECULAR CHAPERONES; PEPTIDE TERMINATION FACTORS; TRANS-ACTIVATORS; VIRULENCE;

EID: 0035351102     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1078/1438-4221-00111     Document Type: Article

References (74)

1. K.E. Beauregard K.D. Lee R.J. Collier J.A. Swanson pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes J. Exp. Med. 186 1997 1159 1163
2. J. Behari P. Youngman A homolog of CcpA mediates catabolite control in Listeria monocytogenes but not carbon source regulation of virulence genes J. Bacteriol. 180 1998 6316 6324
3. J. Behari P. Youngman Regulation of hly expression in Listeria monocytogenes by carbon sources and pH occurs through separate mechanisms mediated by PrfA Infect. Immun. 66 1998 3635 3642
4. R. Böckmann C. Dickneite W. Goebel Z. Sokolovic PrfA mediates specific binding of RNA polymerase to PrfA-dependent virulence gene promoters resulting in a transcriptionally active complex Mol. Microbiol. 36 2000 487 497
5. R. Böckmann C. Dickneite B. Middendorf W. Goebel Z. Sokolovic Specific binding of the Listeria monocytogenes transcriptional regulator protein c to target sequences requires additional factor(s) and is influenced by iron Mol. Microbiol. 22 1996 643 653
6. J. Bohne H. Kestler C. Uebele Z. Sokolovic W. Goebel Differential regulation of the virulence genes of Listeria monocytogenes Mol. Microbiol. 20 1996 1189 1198
7. J. Bohne Z. Sokolovic W. Goebel Transcriptional regulation of PrfA and PrfA-regulated virulence genes in L. monocytogenes Mol. Microbiol. 11 1994 1141 1150
8. K. Brehm J. Kreft M.T. Ripio J.A. Vazquez-Boland Regulation of virulence gene expression in pathogenic Listeria Microbiologia 12 1996 219 236
9. K. Brehm M.T. Ripio J. Kreft J.A. Vazquez-Boland The bvr locus of Listeria monocytogenes mediates virulence gene repression by β-glucosides J. Bacteriol. 181 1999 5024 5032
10. A. Bubert H. Kestler M. Götz R. Böckmann W. Goebel The Listeria monocytogenes iap gene as an indicator gene for the study of PrfA-dependent regulation Mol. Gen. Genet. 256 1997 54 62
11. A. Bubert Z. Sokolovic S.K. Chun L. Papatheodorou A. Simm W. Goebel Differential expression of Listeria monocytogenes virulence genes in mammalian host cells Mol. Gen. Genet. 261 1999 323 336
12. S. Busby R.H. Ebright Transcription activation at class II CAP-dependent promoters Mol. Microbiol. 23 1997 853 859
13. T. Chakraborty M. Leimeister-Wächter E. Domann M. Hartl W. Goebel T. Nichterlein S. Notermans Coordinate regulation of virulence genes in Listeria monocytogenes requires the product of the PrfA gene J. Bacteriol. 174 1992 568 574
14. J. Chen K.S. Mattews Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation J. Biol. Chem. 267 1992 13843 13850
15. M.P. Conte C. Longhi G. Petrone M. Polidoro P. Valenti L. Seganti Modulation of actA gene expression in Listeria monocytogenes by iron J. Med. Microbiol. 49 2000 681 683
16. M.P. Conte C. Longhi M. Polidoro G. Petrone V. Buonfiglio S. Di Santo E. Papi L. Seganti P. Visca P. Valenti Iron availability affects entry of Listeria monocytogenes into the enterocyte-like cell line Caco-2 Infect. Immun. 64 1996 3925 3929
17. P.D. Cotter N. Emerson C.G.M. Gahan C. Hill Identification and disruption of lisRK , a genetic locus encoding a two-component signal transduction system involved in stress tolerance and virulence in Listeria monocytogenes J. Bacteriol. 181 1999 6840 6843
18. C. Dickneite R. Böckmann A. Spory W. Goebel Z. Sokolovic Differential interaction of the transcription factor PrfA and the PrfA-activating factor (Paf) of Listeria monocytogenes with target sequences Mol. Microbiol. 27 1998 915 928
19. E. Domann J. Wehland K. Niebuhr C. Haffner M. Leimeister-Wächter T. Chakraborty Detection of a PrfA -independent promoter responsible for listeriolysin gene expression in mutant Listeria monocytogenes strains lacking the PrfA regulator Infect. Immun. 61 1993 3073 3075
20. S. Dramsi C. Kocks C. Forestier P. Cossart Internalin-mediated invasion of epithelial cells by Listeria monocytogenes is regulated by the bacterial growth state, temperature and the pleiotropic activator PrfA Mol. Microbiol. 9 1993 931 941
21. I. Dubail P. Berche A. Charbit Listeriolysin O as a reporter to identify constitutive and in vivo-inducible promoters in the pathogen Listeria monocytogenes Infect. Immun. 68 2000 3242 3250
22. F. Engelbrecht S.K. Chun C. Ochs J. Hess F. Lottspeich W. Goebel Z. Sokolovic A new PrfA-regulated gene of Listeria monocytogenes encoding a small, secreted protein which belongs to the family of internalins Mol. Microbiol. 21 1996 823 837
23. J.M. Farber P.I. Peterkin Listeria monocytogenes , a food-borne pathogen Microbiol. Rev. 55 1991 476 511
24. N.E. Freitag D.A. Portnoy Dual promoters of the Listeria monocytogenes PrfA transcriptional activator appear essential in vitro but are redundant in vivo Mol. Microbiol. 12 1994 845 853
25. N.E. Freitag K.E. Jacobs Examination of Listeria monocytogenes intracellular gene expression by using the green fluorescent protein of Aquorea victoria Infect. Immun. 67 1999 1844 1852
26. N.E. Freitag L. Rong D.A. Portnoy Regulation of the PrfA transcriptional activator of Listeria monocytogenes : multiple promoter elements contribute to intracellular growth and cell-to-cell spread Infect. Immun. 61 1993 2537 2544
27. N.E. Freitag P. Youngman D.A. Portnoy Transcriptional activation of the Listeria monocytogenes hemolysin gene in Bacillus subtilis J. Bacteriol. 174 1992 1293 1298
28. C.G. Gahan C. Hill The use of listeriolysin to identify in vivo induced genes in the gram-positive intracellular pathogen Listeria monocytogenes Mol. Microbiol. 36 2000 498 507
29. J.L. Gaillard P. Berche C. Frehel E. Gouin P. Cossart Entry of Listeria monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci Cell 65 1991 1127 1141
30. O. Gaillot E. Pellegrini S. Bregenholt S. Nair P. Berche The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes Mol. Microbiol. 35 2000 1286 1294
31. W. Goebel J. Kreft R. Böckmann Regulation of virulence genes in pathogenic Listeria V.A. Fischetti R.P. Novick J.J. Ferretti D.A. Portnoy J.I. Rood Gram-positive pathogens 2000 American Society for Microbiology Washington D. C. 499 506
32. E. Huillet S. Larpin P. Pardon P. Berche Identification of a new locus in Listeria monocytogenes involved in cellobiose-dependent repression of hly expression FEMS Microbiol. Lett. 174 1999 265 272
33. I. Karunasagar R. Lampidis W. Goebel J. Kreft Complementation of Listeria seeligeri with the plcA-PrfA genes from L. monocytogenes activates transcription of seeligerolysin and leads to bacterial escape from the phagosome of infected mammalian cells FEMS Microbiol. Lett. 146 1997 303 310
34. M.J. Kennedy R.J. Yancey M.S. Sanchez R.A. Rzepkowski S.M. Kely R. Curtiss Attenuation and immunogenicity of Deltacya Deltacrp derivatives of Salmonella cholerasuis in pigs Infect. Immun. 67 1999 4628 4636
35. A.D. Klarsfeld P.L. Goossens P. Cossart Five Listeria monocytogenes genes preferentially expressed in infected mammalian cells: plcA, purH, purD, pyrE and an arginine ABC transporter gene, arpJ Mol. Microbiol. 13 1994 585 597
36. A. Kolb S. Busby H. Buc S. Garges S. Adhya Transcriptional regulation by cAMP and its receptor protein Annu. Rev. Biochem. 62 1993 749 795
37. J. Kreft J. Bohne R. Gross H. Kestler Z. Sokolovic W. Goebel Control of Listeria monocytogenes virulence by the transcriptional regulator PrfA R. Rappuoli V. Scarlato B. Arico Signal transduction and bacterial virulence 1995 R. G. Landes Company Austin 129 142
38. J. Kreft J.A. Vazquez-Boland E. Ng W. Goebel Virulence gene clusters and putative pathogenicity islands in Listeria J. Kaper J. Hacker Pathogenicity islands and other mobile virulence elements 1999 American Society for Microbiology Washington, D. C. 219 232
39. M. Kuhn W. Goebel Internalization of Listeria monocytogenes by non-professional and professional phagocytes Subcell. Biochem. 33 2000 411 436
40. R. Lampidis R. Gross Z. Sokolovic W. Goebel J. Kreft The virulence regulator protein of Listeria ivanovii is highly homologous to PrfA from Listeria monocytogenes and both belong to the Crp-Fnr family of transcription regulators Mol. Microbiol. 13 1994 141 151
41. M. Leimeister-Wächter E. Domann T. Chakraborty The expression of virulence genes in Listeria monocytogenes is thermoregulated J. Bacteriol. 174 1992 947 951
42. M. Leimeister-Wächter C. Haffner E. Domann W. Goebel T. Chakraborty Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of Listeria monocytogenes Proc. Natl. Acad. Sci. USA 87 1990 8336 8340
43. A. Lingnau E. Domann M. Hudel M. Bock T. Nichterlein J. Wehland T. Chakraborty Expression of Listeria monocytogenes EGD inlA and inlB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and -independent mechanisms Infect. Immun. 64 1995 1002 1007
44. J. Mengaud S. Dramsi E. Gouin J.A. Vazquez-Boland G. Milon P. Cossart Pleiotropic control of Listeria monocytogenes virulence factors by a gene that is auto-regulated Mol. Microbiol. 5 1991 2273 2283
45. A.A. Milenbachs D.P. Brown M.A. Moors P. Youngman Carbon source regulation of virulence gene expression in Listeria monocytogenes Mol. Microbiol. 23 1997 1075 1085
46. E.R. Myers A.W. Dallmier S.E. Martin Sodium chloride, potassium chloride, and virulence in Listeria monocytogenes Appl. Environ. Microbiol. 59 1993 2082 2086
47. S. Nair I. Derré T. Msadek O. Gaillot P. Berche CtsR is a repressor of the class III heat shock genes in the human pathogen Listeria monocytogenes Mol. Microbiol. 35 2000 800 811
48. S. Nair C. Frehel L. Nguyen V. Escuyer P. Berche ClpE, a novel member of the HSP100 family, is involved in cell division and virulence of Listeria monocytogenes Mol. Microbiol. 31 1999 185 196
49. S. Nair E. Milohanic P. Berche ClpC ATPase is required for cell adhesion and invasion of Listeria monocytogenes Infect. Immun. 68 2000 7061 7068
50. S.F. Park R.G. Kroll Expression of listeriolysin and phosphatidylinositol-specific phospholipase C is repressed by the plant-derived molecule cellobiose in Listeria monocytogenes Mol. Microbiol. 8 1993 653 661
51. D.A. Portnoy T. Chakraborty W. Goebel P. Cossart Molecular determinants of Listeria monocytogenes pathogenesis Infect. Immun. 60 1992 1263 1267
52. D. Raffelsbauer A. Bubert F. Engelbrecht J. Scheinpflug A. Simm J. Hess S.H.E. Kaufmann W. Goebel The gene cluster inl C2DE of Listeria monocytogenes contains additional new internalin genes and is important for virulence in mice Mol. Gen. Genet. 260 1998 144 158
53. A. Renzoni P. Cossart S. Dramsi PrfA, the transcriptional activator of virulence genes, is upregulated during interaction of Listeria monocytogenes with mammalian cells and in eukaryotic cell extracts Mol. Microbiol. 34 1999 552 561
54. A. Renzoni A. Klarsfeld S. Dramsi P. Cossart Evidence that PrfA, the pleiotropic activator of virulence genes in Listeria monocytogenes , can be present but inactive Infect. Immun. 65 1997 1515 1518
55. M.T. Ripio K. Brehm M. Lara M. Suárez J.A. Vázquez-Boland Glucose-1-phosphate utilization by Listeria monocytogenes is PrfA dependent and coordinately expressed with virulence factors J. Bacteriol. 197 1997 7174 7180
56. M.T. Ripio G. Dominguez-Bernal M. Suárez K. Brehm P. Berche J.A. Vázquez-Boland Transcriptional activation of virulence genes in wild-type strains of Listeria monocytogenes in response to a change in the extracellular medium composition Res. Microbiol. 147 1996 311 384
57. M.T. Ripio G. Dominguez-Bernal M. Lara M. Suárez J.A. Vázquez-Boland A Gly145Ser substitution in the transcriptional activator PrfA causes constitutive overexpression of virulence factors in Listeria monocytogenes J. Bacteriol. 179 1997 1533 1540
58. M.T. Ripio K. Brehm M. Lara M. Suárez J.A. Vázquez-Boland Glucose-1-phosphate utilization by Listeria monocytogenes is PrfA dependent and coordinately expressed with virulence factors J. Bacteriol. 197 1997 7174 7180
59. M.T. Ripio J.A. Vazquez-Boland Y. Vega S. Nair P. Berche Evidence for expressional crosstalk between the central virulence regulator PrfA and the stress response mediator ClpC in Listeria monocytogenes FEMS Microbiol. Lett. 158 1998 45 50
60. 54) gene from Listeria monocytogenes is involved in resistance to mesentericin Y105, an antibacterial peptide from Leuconostoc mesenteroides J. Bacteriol. 179 1997 7591 7594
61. nd edition 1999 Marcel Dekker Inc. New York 1 20
62. C. Rouquette C. de Chastellier S. Nair P. Berche The ClpC ATPase of Listeria monocytogenes is a general stress protein required for virulence and promoting early bacterial escape from the phagosome of macrophages Mol. Microbiol. 27 1998 1235 1245
63. C. Rouquette M.T. Ripio E. Pellegrini J.M. Bolla R.I. Tascon J.A. Vazquez-Boland P. Berche Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes Mol. Microbiol. 21 1996 977 987
64. B. Sheehan A. Klarsfeld R. Ebright P. Cossart A single substitution in the putative helix-turn-helix motiv of the pleiotropic activator PrfA attenuates Listeria monocytogenes virulence Mol. Microbiol. 20 1996 785 797
65. B. Sheehan A. Klarsfeld T. Msadek P. Cossart Differential activation of virulence gene expression by PrfA, the Listeria monocytogenes virulence regulator J. Bacteriol. 177 1995 6469 6476
66. Z. Sokolovic A. Fuchs M. Wuenscher W. Goebel Synthesis of species-specific stress proteins by virulent strains of Listeria monocytogenes Infect. Immun. 58 1990 3582 3587
67. Z. Sokolovic J. Riedel M. Wuenscher W. Goebel Surface-associated, PrfA-regulated proteins of Listeria monocytogenes synthesized under stress conditions Mol. Microbiol. 8 1993 219 227
68. S. Spiro J.R. Guest FNR and its role in oxygen-regulated gene expression in Escherichia coli FEMS Microbiol. Rev. 75 1990 399 482
69. R.I. Tascon J.A. Vazquez-Boland C.B. Gutierrez-Martin J.I. Rodriguez-Barbosa E.F. Rodriguez-Ferri Virulence factors of the swine pathogen Actinobacillus pleuropneumoniae Microbiologia 12 1996 171 184
70. J.A. Vazquez-Boland G. Dominguez-Bernal J. Kreft W. Goebel Pathogenicity islands and virulence evolution in Listeria Microb. Infect. 2001 in press
71. J.A. Vázquez-Boland M. Kuhn P. Berche T. Chakraborty G. Domínguez-Bernal W. Goebel J. Wehland J. Kreft Listeria pathogenesis and molecular virulence determinants Clin. Microbiol. Rev. 2001 in press
72. * (Gly145Ser) mutation increases binding affinity for target DNA J. Bacteriol. 180 1998 6655 6660
73. B and its role in acid tolerance and virulence of Listeria monocytogenes J. Bacteriol. 180 1998 3650 3656
74. J.R. Williams C. Thayyullathil N.E. Freitag Sequence variations within PrfA DNA binding sites and effects on Listeria monocytogenes virulence gene expression J. Bacteriol. 182 2000 837 841