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Volumn 5, Issue 2, 2008, Pages 79-89

Interleukin-7 receptor signaling network: An integrated systems perspective

Author keywords

cytokine; IL 7 receptor; modeling; signaling network; systems biology

Indexed keywords

INTERLEUKIN 7 RECEPTOR; LIGAND;

EID: 44949223609     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2008.10     Document Type: Review
Times cited : (93)

References (55)
  • 1
    • 18944379196 scopus 로고    scopus 로고
    • The many faces of IL-7: From lymphopoiesis to peripheral T cell maintenance
    • Fry TJ, Mackall CL. The many faces of IL-7: from lymphopoiesis to peripheral T ce (Pubitemid 40705615)
    • (2005) Journal of Immunology , vol.174 , Issue.11 , pp. 6571-6576
    • Fry, T.J.1    Mackall, C.L.2
  • 3
    • 33846632842 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression: Intelligent design
    • DOI 10.1038/nri2023, PII NRI2023
    • Mazzucchelli R, Durum SK. Interleukin-7 receptor expression: intelligent design. Nat Rev Immunol. 2007;7:144-154. (Pubitemid 46178275)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.2 , pp. 144-154
    • Mazzucchelli, R.1    Durum, S.K.2
  • 6
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med. 1995;181:1519-1526.
    • (1995) J Exp Med , vol.181 , pp. 1519-1526
    • Von Freeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Burdach, S.E.5    Murray, R.6
  • 7
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, Morrissey PJ, Grabstein KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med. 1994;180:1955-1960.
    • (1994) J Exp Med , vol.180 , pp. 1955-1960
    • Peschon, J.J.1    Morrissey, P.J.2    Grabstein, K.H.3
  • 11
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • DOI 10.1016/j.immuni.2004.07.016, PII S1074761304002031
    • Park JH, Yu Q, Erman B, et al. Suppression of IL7Rα transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity. 2004;21:289-302. (Pubitemid 39094057)
    • (2004) Immunity , vol.21 , Issue.2 , pp. 289-302
    • Park, J.-H.1    Yu, Q.2    Erman, B.3    Appelbaum, J.S.4    Montoya-Durango, D.5    Grimes, H.L.6    Singer, A.7
  • 12
    • 27244450756 scopus 로고    scopus 로고
    • Systems biology approaches in cell signaling research
    • Chen RE, Thorner J. Systems biology approaches in cell signaling research. Genome Biol. 2005;6:235.
    • (2005) Genome Biol , vol.6 , pp. 235
    • Chen, R.E.1    Thorner, J.2
  • 13
    • 0037119351 scopus 로고    scopus 로고
    • Cytokine and cytokine receptor pleiotropy and redundancy
    • DOI 10.1074/jbc.R200003200
    • Ozaki K, Leonard WJ. Cytokine and cytokine receptor pleiotropy and redundancy. J Biol Chem. 2002;277:29355-29358. (Pubitemid 41079217)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.33 , pp. 29355-29358
    • Ozaki, K.1    Leonard, W.J.2
  • 15
    • 0034232353 scopus 로고    scopus 로고
    • Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin
    • Pandey A, Ozaki K, Baumann H, et al. Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin. Nat Immunol. 2000;1:59-64.
    • (2000) Nat Immunol , vol.1 , pp. 59-64
    • Pandey, A.1    Ozaki, K.2    Baumann, H.3
  • 16
    • 0031570470 scopus 로고    scopus 로고
    • Association of the Common γ-Chain with the Human IL-7 Receptor Is Modulated by T Cell Activation
    • Page TH, Lali FV, Groome N, Foxwell BM. Association of the common γ-chain with the human IL-7 receptor is modulated by T cell activation. J Immunol. 1997;158:5727-5735. (Pubitemid 127483977)
    • (1997) Journal of Immunology , vol.158 , Issue.12 , pp. 5727-5735
    • Page, T.H.1    Lali, F.V.2    Groome, N.3    Foxwell, B.M.J.4
  • 17
    • 34347392492 scopus 로고    scopus 로고
    • Limiting γc expression differentially affects signaling via the interleukin (IL)-7 and IL-15 receptors
    • DOI 10.1182/blood-2006-11-055442
    • Smyth CM, Ginn SL, Deakin CT, Logan GJ, Alexander IE. Limiting γc expression differentially affects signaling via the interleukin (IL)-7 and IL-15 receptors. Blood. 2007;110:91-98. (Pubitemid 47026823)
    • (2007) Blood , vol.110 , Issue.1 , pp. 91-98
    • Smyth, C.M.1    Ginn, S.L.2    Deakin, C.T.3    Logan, G.J.4    Alexander, I.E.5
  • 18
    • 34547097277 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation
    • quiz 245-246
    • Liu YJ. Thymic stromal lymphopoietin and OX40 ligand pathway in the initiation of dendritic cell-mediated allergic inflammation. J Allergy Clin Immunol. 2007;120:238-244; quiz 245-246.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 238-244
    • Liu, Y.J.1
  • 19
    • 33745207614 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin in normal and pathogenic T cell development and function
    • DOI 10.1038/ni1360, PII N1360
    • Ziegler SF, Liu YJ. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol. 2006;7:709-714. (Pubitemid 43905869)
    • (2006) Nature Immunology , vol.7 , Issue.7 , pp. 709-714
    • Ziegler, S.F.1    Liu, Y.-J.2
  • 21
    • 0035081770 scopus 로고    scopus 로고
    • Cutaneous interleukin-7 transgenic mice display a propitious environment to Schistosoma mansoni infection
    • DOI 10.1046/j.1365-3024.2001.00365.x
    • Roye O, Delacre M, Williams IR, Auriault C, Wolowczuk I. Cutaneous interleukin-7 transgenic mice display a propitious environment to Schistosoma mansoni infection. Parasite Immunol. 2001;23:133-140. (Pubitemid 32231915)
    • (2001) Parasite Immunology , vol.23 , Issue.3 , pp. 133-140
    • Roye, O.1    Delacre, M.2    Williams, I.R.3    Auriault, C.4    Wolowczuk, I.5
  • 22
    • 33344455022 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin: Master switch for allergic inflammation
    • Liu YJ. Thymic stromal lymphopoietin: master switch for allergic inflammation. J Exp Med. 2006;203:269-273.
    • (2006) J Exp Med , vol.203 , pp. 269-273
    • Liu, Y.J.1
  • 23
    • 34547108380 scopus 로고    scopus 로고
    • JAK-STAT signaling: From interferons to cytokines
    • DOI 10.1074/jbc.R700016200
    • Schindler C, Levy DE, Decker T. JAK-STAT signaling: from interferons to cytokines. J Biol Chem. 2007;282:20059-20063. (Pubitemid 47099977)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20059-20063
    • Schindler, C.1    Levy, D.E.2    Decker, T.3
  • 24
    • 0031570471 scopus 로고    scopus 로고
    • The IL-4 Receptor α-Chain Cytoplasmic Domain Is Sufficient for Activation of JAK-1 and STAT6 and the Induction of IL-4-Specific Gene Expression
    • Reichel M, Nelson BH, Greenberg PD, Rothman PB. The IL-4 receptor α-chain cytoplasmic domain is sufficient for activation of JAK-1 and STAT6 and the induction of IL-4-specific gene expression. J Immunol. 1997;158:5860-5867. (Pubitemid 127483993)
    • (1997) Journal of Immunology , vol.158 , Issue.12 , pp. 5860-5867
    • Reichel, M.1    Nelson, B.H.2    Greenberg, P.D.3    Rothman, P.B.4
  • 25
    • 0028114542 scopus 로고
    • Prevention of T cell anergy by signaling through the γc chain of the IL-2 receptor
    • Boussiotis VA, Barber DL, Nakarai T, et al. Prevention of T cell anergy by signaling through the γc chain of the IL-2 receptor. Science. 1994;266:1039-1042.
    • (1994) Science , vol.266 , pp. 1039-1042
    • Boussiotis, V.A.1    Barber, D.L.2    Nakarai, T.3
  • 26
    • 0028962572 scopus 로고
    • The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
    • Lin JX, Migone TS, Tsang M, et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity. 1995;2:331-339.
    • (1995) Immunity , vol.2 , pp. 331-339
    • Lin, J.X.1    Migone, T.S.2    Tsang, M.3
  • 27
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • DOI 10.1038/nri2093, PII NRI2093
    • Yoshimura A, Naka T, Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat Rev Immunol. 2007;7: 454-465. (Pubitemid 46834848)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 28
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • DOI 10.1126/science.296.5573.1655
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science. 2002;296:1655-1657. (Pubitemid 34579158)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1655-1657
    • Cantley, L.C.1
  • 29
    • 9144241114 scopus 로고    scopus 로고
    • Cutting edge: Transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15Rα by the same cells
    • Sandau MM, Schluns KS, Lefrancois L, Jameson SC. Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15Rα by the same cells. J Immunol. 2004;173:6537-6541. (Pubitemid 39541036)
    • (2004) Journal of Immunology , vol.173 , Issue.11 , pp. 6537-6541
    • Sandau, M.M.1    Schluns, K.S.2    Lefrancois, L.3    Jameson, S.C.4
  • 30
    • 0029791838 scopus 로고    scopus 로고
    • Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase
    • DOI 10.1038/nm0996-1022
    • Kuhl PR, Griffith-Cima LG. Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase. Nat Med. 1996;2:1022-1027. (Pubitemid 26306842)
    • (1996) Nature Medicine , vol.2 , Issue.9 , pp. 1022-1027
    • Kuhl, P.R.1    Griffith-Cima, L.G.2
  • 32
    • 9644295710 scopus 로고    scopus 로고
    • c-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
    • DOI 10.1111/j.0105-2896.2004.00203.x
    • Kovanen PE, Leonard WJ. Cytokines and immunodeficiency diseases: critical roles of the γc-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways. Immunol Rev. 2004;202:67-83. (Pubitemid 39576905)
    • (2004) Immunological Reviews , vol.202 , pp. 67-83
    • Kovanen, P.E.1    Leonard, W.J.2
  • 33
    • 0028025041 scopus 로고
    • Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the α chain of the interleukin-7 receptor
    • Venkitaraman AR, Cowling RJ. Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the α chain of the interleukin-7 receptor. Eur J Immunol. 1994;24:2168-2174. (Pubitemid 24276551)
    • (1994) European Journal of Immunology , vol.24 , Issue.9 , pp. 2168-2174
    • Venkitaraman, A.R.1    Cowling, R.J.2
  • 34
    • 31344480910 scopus 로고    scopus 로고
    • Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
    • DOI 10.1084/jem.20051836
    • Yu Q, Park JH, Doan LL, Erman B, Feigenbaum L, Singer A. Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection. J Exp Med. 2006;203:165-175. (Pubitemid 43139655)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.1 , pp. 165-175
    • Yu, Q.1    Park, J.-H.2    Doan, L.L.3    Erman, B.4    Feigenbaum, L.5    Singer, A.6
  • 36
    • 0036217915 scopus 로고    scopus 로고
    • E protein function in lymphocyte development
    • DOI 10.1146/annurev.immunol.20.092501.162048
    • Quong MW, Romanow WJ, Murre C. E protein function in lymphocyte development. Annu Rev Immunol. 2002;20:301-322. (Pubitemid 34293427)
    • (2002) Annual Review of Immunology , vol.20 , pp. 301-322
    • Quong, M.W.1    Romanow, W.J.2    Murre, C.3
  • 37
    • 18744404228 scopus 로고    scopus 로고
    • Genetic networks that regulate B lymphopoiesis
    • DOI 10.1097/01.moh.0000160735.67596.a0
    • Medina KL, Singh H. Genetic networks that regulate B lymphopoiesis. Curr Opin Hematol. 2005;12:203-209. (Pubitemid 40676827)
    • (2005) Current Opinion in Hematology , vol.12 , Issue.3 , pp. 203-209
    • Medina, K.L.1    Singh, H.2
  • 38
    • 2542442633 scopus 로고    scopus 로고
    • Transcriptional control of early B cell development
    • DOI 10.1146/annurev.immunol.22.012703.104807
    • Busslinger M. Transcriptional control of early B cell development. Annu Rev Immunol. 2004;22:55-79. (Pubitemid 38680418)
    • (2004) Annual Review of Immunology , vol.22 , pp. 55-79
    • Busslinger, M.1
  • 40
    • 33750561716 scopus 로고    scopus 로고
    • Interleukin-7 receptor expression on CD8 T-cells is downregulated by the HIV Tat protein
    • DOI 10.1097/01.qai.0000230319.78288.f4, PII 0012633420061101000002
    • Faller EM, McVey MJ, Kakal JA, MacPherson PA. Interleukin-7 receptor expression on CD8 T-cells is downregulated by the HIV Tat protein. J Acquir Immune Defic Syndr. 2006;43:257-269. (Pubitemid 44674005)
    • (2006) Journal of Acquired Immune Deficiency Syndromes , vol.43 , Issue.3 , pp. 257-269
    • Faller, E.M.1    McVey, M.J.2    Kakal, J.A.3    MacPherson, P.A.4
  • 41
    • 0038813748 scopus 로고    scopus 로고
    • c-family cytokine target genes: Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling
    • DOI 10.1074/jbc.M209015200
    • Kovanen PE, Rosenwald A, Fu J, et al. Analysis of γc-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling. J Biol Chem. 2003;278:5205-5213. (Pubitemid 36801033)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.7 , pp. 5205-5213
    • Kovanen, P.E.1    Rosenwald, A.2    Fu, J.3    Hurt, E.M.4    Lam, L.T.5    Giltnane, J.M.6    Wright, G.7    Staudt, L.M.8    Leonard, W.J.9
  • 45
    • 17844391857 scopus 로고    scopus 로고
    • Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
    • DOI 10.1080/10428190400027852
    • Barata JT, Cardoso AA, Boussiotis VA. Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis? Leuk Lymphoma. 2005;46:483-495. (Pubitemid 40584864)
    • (2005) Leukemia and Lymphoma , vol.46 , Issue.4 , pp. 483-495
    • Barata, J.T.1    Cardoso, A.A.2    Boussiotis, V.A.3
  • 46
    • 0033988447 scopus 로고    scopus 로고
    • DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites
    • Soldaini E, John S, Moro S, Bollenbacher J, Schindler U, Leonard WJ. DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites. Mol Cell Biol. 2000;20:389-401. (Pubitemid 30002580)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.1 , pp. 389-401
    • Soldaini, E.1    John, S.2    Moro, S.3    Bollenbacher, J.4    Schindler, U.5    Leonard, W.J.6
  • 48
    • 16844386089 scopus 로고    scopus 로고
    • Regulation of mature T cell homeostasis
    • DOI 10.1016/j.smim.2005.02.007, Counting on Hemeostasis: Governing the Size and Composition of Lymphocyte Pools
    • Surh CD, Sprent J. Regulation of mature T cell homeostasis. Semin Immunol. 2005;17:183-191. (Pubitemid 40488977)
    • (2005) Seminars in Immunology , vol.17 , Issue.3 , pp. 183-191
    • Surh, C.D.1    Sprent, J.2
  • 54
    • 24144480562 scopus 로고    scopus 로고
    • + regulatory T cells in human thymus
    • DOI 10.1038/nature03886
    • Watanabe N, Wang YH, Lee HK, Ito T, Cao W, Liu YJ. Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature. 2005;436:1181-1185. (Pubitemid 41232298)
    • (2005) Nature , vol.436 , Issue.7054 , pp. 1181-1185
    • Watanabe, N.1    Wang, Y.-H.2    Lee, H.K.3    Ito, T.4    Wang, Y.-H.5    Cao, W.6    Liu, Y.-J.7


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