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Volumn 158, Issue 12, 1997, Pages 5860-5867

The IL-4 Receptor α-Chain Cytoplasmic Domain Is Sufficient for Activation of JAK-1 and STAT6 and the Induction of IL-4-Specific Gene Expression

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN RECEPTOR; JAK1 PROTEIN, HUMAN; JAK3 PROTEIN, HUMAN; JANUS KINASE 1; JANUS KINASE 3; LEUKOCYTE ANTIGEN; PROTEIN TYROSINE KINASE; STAT6 PROTEIN; STAT6 PROTEIN, HUMAN; STEM CELL FACTOR RECEPTOR; TRANSACTIVATOR PROTEIN; TYROSINE;

EID: 0031570471     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (63)

References (49)
  • 1
    • 0026598960 scopus 로고
    • Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex
    • de Vos, A., M. Ultsch, and A. A. Kossiakoff. 1992. Human growth hormone and extracellular domain of its receptor: crystal structure of the complex. Science 255:306.
    • (1992) Science , vol.255 , pp. 306
    • De Vos, A.1    Ultsch, M.2    Kossiakoff, A.A.3
  • 8
  • 9
    • 0029001660 scopus 로고
    • Components of a Stat recognition code: Evidence for two layers of molecular selectivity
    • Schindler, U., P. Wu, M. Rothe, M. Brasseur, and S. L. McKnight. 1995. Components of a Stat recognition code: evidence for two layers of molecular selectivity. Immunity 2:689.
    • (1995) Immunity , vol.2 , pp. 689
    • Schindler, U.1    Wu, P.2    Rothe, M.3    Brasseur, M.4    McKnight, S.L.5
  • 10
    • 0027731604 scopus 로고
    • Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4
    • Kondo, M., T. Takeshita, N. Ishii, M. Nakamura, S. Watanabe, K.-I. Arai, and K. Sugamura. 1993. Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 262:1874.
    • (1993) Science , vol.262 , pp. 1874
    • Kondo, M.1    Takeshita, T.2    Ishii, N.3    Nakamura, M.4    Watanabe, S.5    Arai, K.-I.6    Sugamura, K.7
  • 14
    • 0028244396 scopus 로고
    • Involvement of the JAK-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
    • Witthuhn, B. A., O. Silvennoinen, O. Miura, K. S. Lai, C. Cwik, E. T. Liu, and J. N. Ihle. 1994. Involvement of the JAK-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 370:153.
    • (1994) Nature , vol.370 , pp. 153
    • Witthuhn, B.A.1    Silvennoinen, O.2    Miura, O.3    Lai, K.S.4    Cwik, C.5    Liu, E.T.6    Ihle, J.N.7
  • 15
    • 0028149328 scopus 로고
    • JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes
    • Yin, T., M. L. Tsang, and T. C. Yang. 1994. JAK1 kinase forms complexes with interleukin-4 receptor and 4PS/insulin receptor substrate-1-like protein and is activated by interleukin-4 and interleukin-9 in T lymphocytes. J. Biol. Chem. 269:26614.
    • (1994) J. Biol. Chem. , vol.269 , pp. 26614
    • Yin, T.1    Tsang, M.L.2    Yang, T.C.3
  • 16
    • 0029069145 scopus 로고
    • Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
    • Schindler, C., and J. E. Darnell. 1995. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu. Rev. Biochem. 64:621.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 621
    • Schindler, C.1    Darnell, J.E.2
  • 17
    • 0028225367 scopus 로고
    • Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor
    • Izuhara, K., R. A. Feldman, P. Greer, and N. Harada. 1994. Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor. J. Biol. Chem. 269: 18623.
    • (1994) J. Biol. Chem. , vol.269 , pp. 18623
    • Izuhara, K.1    Feldman, R.A.2    Greer, P.3    Harada, N.4
  • 19
    • 0026526768 scopus 로고
    • Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: Analysis of the promoter/enhancer
    • Xu, M. Z., and J. Stavnezer. 1992. Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer. EMBO J. 11:145.
    • (1992) EMBO J. , vol.11 , pp. 145
    • Xu, M.Z.1    Stavnezer, J.2
  • 20
    • 0027688778 scopus 로고
    • Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
    • Kotanides, H., and N. C. Reich. 1993. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4. Science 262:1265.
    • (1993) Science , vol.262 , pp. 1265
    • Kotanides, H.1    Reich, N.C.2
  • 21
    • 0028917885 scopus 로고
    • Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline ∈ promoter: Regulation by NF-IL4, a C/EBP family member and NF-kB/p50
    • Delphin, S., and J. Stavnezer. 1995. Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline ∈ promoter: regulation by NF-IL4, a C/EBP family member and NF-kB/p50. J. Exp. Med. 181: 181.
    • (1995) J. Exp. Med. , vol.181 , pp. 181
    • Delphin, S.1    Stavnezer, J.2
  • 22
    • 0027331547 scopus 로고
    • Allergy-associated I∈ and Fc∈ receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element
    • Kohler, I., and E. Rieber. 1993. Allergy-associated I∈ AND Fc∈ receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element. Eur. J. Immunol. 23:3066.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3066
    • Kohler, I.1    Rieber, E.2
  • 23
    • 0029876629 scopus 로고    scopus 로고
    • Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells
    • Kaplan, M. H., U. Schindler, S. T. Smiley, and M. J. Grusby. 1996. Stat6 is required for mediating responses to IL-4 and for the development of Th2 cells. Immunity 4:313.
    • (1996) Immunity , vol.4 , pp. 313
    • Kaplan, M.H.1    Schindler, U.2    Smiley, S.T.3    Grusby, M.J.4
  • 26
    • 0029974563 scopus 로고    scopus 로고
    • IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor α chain
    • Wang, H. Y., W. E. Paul, and A. D. Keegan. 1996. IL-4 function can be transferred to the IL-2 receptor by tyrosine containing sequences found in the IL-4 receptor α chain. Immunity 4:113.
    • (1996) Immunity , vol.4 , pp. 113
    • Wang, H.Y.1    Paul, W.E.2    Keegan, A.D.3
  • 30
    • 0028233154 scopus 로고
    • Interleukin-4 receptor regulation in human monocytic cell lines
    • de Wit, H., D. W. Hendriks, M. R. Halie, and E. Bellenga. 1994. Interleukin-4 receptor regulation in human monocytic cell lines. Blood 84:608.
    • (1994) Blood , vol.84 , pp. 608
    • De Wit, H.1    Hendriks, D.W.2    Halie, M.R.3    Bellenga, E.4
  • 31
    • 0029032061 scopus 로고
    • c chain does not function as a subunit shared by the IL-4 and IL-13 receptors
    • c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. J. Immunol. 155:9.
    • (1995) J. Immunol. , vol.155 , pp. 9
    • He, Y.-W.1    Malek, T.R.2
  • 32
    • 0028797453 scopus 로고
    • Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15
    • Matthews, D. J., P. A. Clark, J. Herbert, G. Morgan, R. J. Armitage, C. Kinnon, A. Minty, K. H. Grabstein, D. Caput, P. Ferrara, and R. Callard. 1995. Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood 85:38.
    • (1995) Blood , vol.85 , pp. 38
    • Matthews, D.J.1    Clark, P.A.2    Herbert, J.3    Morgan, G.4    Armitage, R.J.5    Kinnon, C.6    Minty, A.7    Grabstein, K.H.8    Caput, D.9    Ferrara, P.10    Callard, R.11
  • 34
    • 0028286628 scopus 로고
    • Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
    • Nelson, B. H., J. D. Lord, and P. D. Greenberg. 1994. Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 369:333.
    • (1994) Nature , vol.369 , pp. 333
    • Nelson, B.H.1    Lord, J.D.2    Greenberg, P.D.3
  • 35
    • 0028350868 scopus 로고
    • Mutants cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3α components
    • Loh, J. E., C. Schindler, A. Ziemiecki, A. G. Harpur, A. F. Wilks, and R. A. Flavell. 1994. Mutants cell lines unresponsive to alpha/beta and gamma interferon are defective in tyrosine phosphorylation of ISGF-3α components. Mol. Cell. Biol. 14:2170.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2170
    • Loh, J.E.1    Schindler, C.2    Ziemiecki, A.3    Harpur, A.G.4    Wilks, A.F.5    Flavell, R.A.6
  • 36
    • 0024520745 scopus 로고
    • Site-directed mutagenesis by overlap extension using the polymerase chain reaction
    • Ho, S. N., H. D. Hunt, R. M. Horton, J. K. Pullen, and L. R. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51.
    • (1989) Gene , vol.77 , pp. 51
    • Ho, S.N.1    Hunt, H.D.2    Horton, R.M.3    Pullen, J.K.4    Pease, L.R.5
  • 37
    • 0026770248 scopus 로고
    • Interferon dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler, C., K. Shuai, V. R. Prezioso, and J. E. Darnell. Jr. 1992. Interferon dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257:809.
    • (1992) Science , vol.257 , pp. 809
    • Schindler, C.1    Shuai, K.2    Prezioso, V.R.3    Darnell Jr., J.E.4
  • 38
    • 0028817880 scopus 로고
    • Jak-Stat signaling induced by the v-abl oncogene
    • Danial, N. N., A. Penis, and P. B. Rothman. 1995. Jak-Stat signaling induced by the v-abl oncogene. Science 269:1875.
    • (1995) Science , vol.269 , pp. 1875
    • Danial, N.N.1    Penis, A.2    Rothman, P.B.3
  • 39
    • 0028177788 scopus 로고
    • IFN-γ represses ∈ germline transcription and subsequently down-regulates switch recombination to ∈
    • Xu, L., and P. Rothman. 1994. IFN-γ represses ∈ germline transcription and subsequently down-regulates switch recombination to ∈. Int. Immunol. 6:515.
    • (1994) Int. Immunol. , vol.6 , pp. 515
    • Xu, L.1    Rothman, P.2
  • 40
    • 0026720074 scopus 로고
    • Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor
    • Lev, S., Y. Yarden, and D. Givol. 1992. Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor. J. Biol. Chem. 267:15970.
    • (1992) J. Biol. Chem. , vol.267 , pp. 15970
    • Lev, S.1    Yarden, Y.2    Givol, D.3
  • 42
    • 0028219966 scopus 로고
    • An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth
    • Keegan, A. D., K. Nelms, M. White, L. M. Wang, J. H. Pierce, and W. E. Paul. 1994. An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. Cell 76:811.
    • (1994) Cell , vol.76 , pp. 811
    • Keegan, A.D.1    Nelms, K.2    White, M.3    Wang, L.M.4    Pierce, J.H.5    Paul, W.E.6
  • 43
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin 4 deficient mice
    • Kuhn, R., K. Rajewsky, and W. Muller. 1991. Generation and analysis of interleukin 4 deficient mice. Science 254:707.
    • (1991) Science , vol.254 , pp. 707
    • Kuhn, R.1    Rajewsky, K.2    Muller, W.3
  • 44
    • 0027372064 scopus 로고
    • Mechanism and regulation of immunoglobulin isotype switching
    • Coffman, R. L., D. A. Lebman, and P. Rothman. 1993. Mechanism and regulation of immunoglobulin isotype switching. Adv. Immunol. 54:229.
    • (1993) Adv. Immunol. , vol.54 , pp. 229
    • Coffman, R.L.1    Lebman, D.A.2    Rothman, P.3
  • 45
    • 0027968558 scopus 로고
    • Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signalling
    • Kawahara, A., Y. Minami, and T. Taniguchi. 1994. Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor γ chain in IL-2, IL-4, and IL-7 signalling. Mol. Cell. Biol. 14:5433.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5433
    • Kawahara, A.1    Minami, Y.2    Taniguchi, T.3
  • 47
    • 0030068217 scopus 로고    scopus 로고
    • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
    • Hilton, D. J., J.-G. Zhang, D. Metcalf, W. S. Alexander, N. A. Nicola, and T. A. Willson. 1996. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. USA 93:497.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 497
    • Hilton, D.J.1    Zhang, J.-G.2    Metcalf, D.3    Alexander, W.S.4    Nicola, N.A.5    Willson, T.A.6
  • 49
    • 0029834119 scopus 로고    scopus 로고
    • Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor α subunit
    • Lai, S. Y., J. Molden, K. D. Liu, J. M. Puck, M. D. White, and M. A. Goldsmith. 1996. Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor α subunit. EMBO J. 15:4506.
    • (1996) EMBO J. , vol.15 , pp. 4506
    • Lai, S.Y.1    Molden, J.2    Liu, K.D.3    Puck, J.M.4    White, M.D.5    Goldsmith, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.