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Volumn 28, Issue 19, 2008, Pages 5029-5039

Localized loss of Ca2+ homeostasis in neuronal dendrites is a downstream consequence of metabolic compromise during extended NMDA exposures

Author keywords

ATP; Brain slice; CA1; Excitotoxicity; Hippocampus; MK 801; Sodium ion

Indexed keywords

CALCIUM; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PYRUVIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; DIZOCILPINE MALEATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; SODIUM;

EID: 44949179393     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5069-07.2008     Document Type: Article
Times cited : (33)

References (52)
  • 1
    • 0042536473 scopus 로고    scopus 로고
    • Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
    • Arundine M, Tymianski M (2003) Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 34:325-337.
    • (2003) Cell Calcium , vol.34 , pp. 325-337
    • Arundine, M.1    Tymianski, M.2
  • 2
    • 0034784359 scopus 로고    scopus 로고
    • An energy budget for signaling in the grey matter of the brain
    • Attwell D, Laughlin SB (2001) An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab 21:1133-1145.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 1133-1145
    • Attwell, D.1    Laughlin, S.B.2
  • 3
    • 29344440424 scopus 로고    scopus 로고
    • Differential responses to NMDAreceptor activation in rat hippocampal interneurons and pyramidal cells may underlie enhanced pyramidal cell vulnerability
    • Avignone E, Frenguelli BG, Irving AJ (2005) Differential responses to NMDAreceptor activation in rat hippocampal interneurons and pyramidal cells may underlie enhanced pyramidal cell vulnerability. Eur J Neurosci 22:3077-3090.
    • (2005) Eur J Neurosci , vol.22 , pp. 3077-3090
    • Avignone, E.1    Frenguelli, B.G.2    Irving, A.J.3
  • 4
    • 0028838282 scopus 로고
    • Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons
    • Bindokas VP, Miller RJ (1995) Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons. J Neurosci 15:6999-7011.
    • (1995) J Neurosci , vol.15 , pp. 6999-7011
    • Bindokas, V.P.1    Miller, R.J.2
  • 5
    • 0035868972 scopus 로고    scopus 로고
    • Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus
    • Brocard JB, Tassetto M, Reynolds IJ (2001) Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus. J Physiol (Lond) 531:793-805.
    • (2001) J Physiol (Lond) , vol.531 , pp. 793-805
    • Brocard, J.B.1    Tassetto, M.2    Reynolds, I.J.3
  • 6
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Budd SL, Nicholls DG (1996) Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurochem 67:2282-2291.
    • (1996) J Neurochem , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 7
    • 0032535275 scopus 로고    scopus 로고
    • Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Castilho RF, Hansson O, Ward MW, Budd SL, Nicholls DG (1998) Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 18:10277-10286.
    • (1998) J Neurosci , vol.18 , pp. 10277-10286
    • Castilho, R.F.1    Hansson, O.2    Ward, M.W.3    Budd, S.L.4    Nicholls, D.G.5
  • 8
    • 0030987928 scopus 로고    scopus 로고
    • Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons
    • Chen QX, Perkins KL, Choi DW, Wong RK (1997) Secondary activation of a cation conductance is responsible for NMDA toxicity in acutely isolated hippocampal neurons. J Neurosci 17:4032-4036.
    • (1997) J Neurosci , vol.17 , pp. 4032-4036
    • Chen, Q.X.1    Perkins, K.L.2    Choi, D.W.3    Wong, R.K.4
  • 11
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi DW (1988a) Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 12
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi DW (1988b) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11:465-469.
    • (1988) Trends Neurosci , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 13
    • 0033988031 scopus 로고    scopus 로고
    • 2+ responses of CA1 hippocampal pyramidal neurons in slice
    • 2+ responses of CA1 hippocampal pyramidal neurons in slice. J Neurophysiol 83:90-98.
    • (2000) J Neurophysiol , vol.83 , pp. 90-98
    • Connor, J.A.1    Cormier, R.J.2
  • 15
    • 34547095250 scopus 로고    scopus 로고
    • Activation of a novel injury-induced calcium permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury
    • Deshpande LS, Limbrick DD, Sombati S, Delorenzo RJ (2007) Activation of a novel injury-induced calcium permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury. J Pharmacol Exp Ther 322:443-452.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 443-452
    • Deshpande, L.S.1    Limbrick, D.D.2    Sombati, S.3    Delorenzo, R.J.4
  • 17
    • 0031443289 scopus 로고    scopus 로고
    • Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro
    • Fischer G, Mutel V, Trube G, Malherbe P, Kew JN, Mohacsi E, Heitz MP, Kemp JA (1997) Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. J Pharmacol Exp Ther 283:1285-1292.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1285-1292
    • Fischer, G.1    Mutel, V.2    Trube, G.3    Malherbe, P.4    Kew, J.N.5    Mohacsi, E.6    Heitz, M.P.7    Kemp, J.A.8
  • 18
    • 0029610441 scopus 로고
    • The importance of sodium for anoxic transmission damage in rat hippocampal slices: Mechanisms of protection by lidocaine
    • Fried E, Amorim P, Chambers G, Cottrell JE, Kass IS (1995) The importance of sodium for anoxic transmission damage in rat hippocampal slices: mechanisms of protection by lidocaine. J Physiol (Lond) 489:557-565.
    • (1995) J Physiol (Lond) , vol.489 , pp. 557-565
    • Fried, E.1    Amorim, P.2    Chambers, G.3    Cottrell, J.E.4    Kass, I.S.5
  • 20
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 24
    • 3543030406 scopus 로고    scopus 로고
    • In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
    • Jekabsons MB, Nicholls DG (2004) In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem 279:32989-33000.
    • (2004) J Biol Chem , vol.279 , pp. 32989-33000
    • Jekabsons, M.B.1    Nicholls, D.G.2
  • 25
    • 34249781383 scopus 로고    scopus 로고
    • Mild Uncoupling does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress
    • Johnson-Cadwell LI, Jekabsons MB, Wang A, Polster BM, Nicholls DG (2007) "Mild Uncoupling" does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J Neurochem 101:1619-1631.
    • (2007) J Neurochem , vol.101 , pp. 1619-1631
    • Johnson-Cadwell, L.I.1    Jekabsons, M.B.2    Wang, A.3    Polster, B.M.4    Nicholls, D.G.5
  • 27
    • 33846783274 scopus 로고    scopus 로고
    • 2+] elevations in cultured hippocampal CA1 neurons during anoxic depolarization
    • 2+] elevations in cultured hippocampal CA1 neurons during anoxic depolarization. J Neurochem 100:915-923.
    • (2007) J Neurochem , vol.100 , pp. 915-923
    • Kiedrowski, L.1
  • 28
    • 0028340999 scopus 로고
    • Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate
    • Kiedrowski L, Wroblewski JT, Costa E (1994) Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate. Mol Pharmacol 45:1050-1054.
    • (1994) Mol Pharmacol , vol.45 , pp. 1050-1054
    • Kiedrowski, L.1    Wroblewski, J.T.2    Costa, E.3
  • 30
    • 35548982628 scopus 로고    scopus 로고
    • Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity
    • Nicholls DG, Johnson-Cadwell L, Vesce S, Jekabsons M, Yadava N (2007) Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity. J Neurosci Res 85:3206-3212.
    • (2007) J Neurosci Res , vol.85 , pp. 3206-3212
    • Nicholls, D.G.1    Johnson-Cadwell, L.2    Vesce, S.3    Jekabsons, M.4    Yadava, N.5
  • 31
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
    • Novelli A, Reilly JA, Lysko PG, Henneberry RC (1988) Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res 451:205-212.
    • (1988) Brain Res , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, J.A.2    Lysko, P.G.3    Henneberry, R.C.4
  • 32
    • 0001933595 scopus 로고
    • Neurotoxicity of excitatory amino acids
    • McGreer EG, Olney JW, McGreer PL, eds, pp, New York: Raven
    • Olney JW (1978) Neurotoxicity of excitatory amino acids. In: Kainic acid as a tool in neurobiology (McGreer EG, Olney JW, McGreer PL, eds), pp 95-121. New York: Raven.
    • (1978) Kainic acid as a tool in neurobiology , pp. 95-121
    • Olney, J.W.1
  • 34
    • 1642317185 scopus 로고    scopus 로고
    • Some precautions in using chelators to buffer metals in biological solutions
    • Patton C, Thompson S, Epel D (2004) Some precautions in using chelators to buffer metals in biological solutions. Cell Calcium 35:427-431.
    • (2004) Cell Calcium , vol.35 , pp. 427-431
    • Patton, C.1    Thompson, S.2    Epel, D.3
  • 35
    • 0028170654 scopus 로고
    • 2+ accumulations and metabotropic glutamate receptor activation associated with an N-methyl-D-aspartate receptor-independent long-term potentiation in hippocampal CA1 neurons
    • 2+ accumulations and metabotropic glutamate receptor activation associated with an N-methyl-D-aspartate receptor-independent long-term potentiation in hippocampal CA1 neurons. Hippocampus 4:546-558.
    • (1994) Hippocampus , vol.4 , pp. 546-558
    • Petrozzino, J.J.1    Connor, J.A.2
  • 36
    • 0028205221 scopus 로고
    • Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons
    • Pinelis VG, Segal M, Greenberger V, Khodorov BI (1994) Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons. Biochem Mol Biol Int 32:475-482.
    • (1994) Biochem Mol Biol Int , vol.32 , pp. 475-482
    • Pinelis, V.G.1    Segal, M.2    Greenberger, V.3    Khodorov, B.I.4
  • 37
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall RD, Thayer SA (1992) Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J Neurosci 12:1882-1895.
    • (1992) J Neurosci , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 38
    • 0035869336 scopus 로고    scopus 로고
    • Mitochondria control AMPA/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells
    • Rego AC, Ward MW, Nicholls DG (2001) Mitochondria control AMPA/kainate receptor-induced cytoplasmic calcium deregulation in rat cerebellar granule cells. J Neurosci 21:1893-1901.
    • (2001) J Neurosci , vol.21 , pp. 1893-1901
    • Rego, A.C.1    Ward, M.W.2    Nicholls, D.G.3
  • 39
    • 0032567695 scopus 로고    scopus 로고
    • Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage
    • Reyes M, Reyes A, Opitz T, Kapin MA, Stanton PK (1998) Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage. Brain Res 782:212-218.
    • (1998) Brain Res , vol.782 , pp. 212-218
    • Reyes, M.1    Reyes, A.2    Opitz, T.3    Kapin, M.A.4    Stanton, P.K.5
  • 40
    • 0021880922 scopus 로고
    • The neurotoxicity of excitatory amino acids is produced by passive chloride influx
    • Rothman SM (1985) The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J Neurosci 5:1483-1489.
    • (1985) J Neurosci , vol.5 , pp. 1483-1489
    • Rothman, S.M.1
  • 42
    • 0035875995 scopus 로고    scopus 로고
    • Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons
    • Shuttleworth CW, Connor JA (2001) Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons. J Neurosci 21:4225-4236.
    • (2001) J Neurosci , vol.21 , pp. 4225-4236
    • Shuttleworth, C.W.1    Connor, J.A.2
  • 43
    • 0021743001 scopus 로고
    • Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain
    • Simon RP, Swan JH, Griffiths T, Meldrum BS (1984) Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science 226:850-852.
    • (1984) Science , vol.226 , pp. 850-852
    • Simon, R.P.1    Swan, J.H.2    Griffiths, T.3    Meldrum, B.S.4
  • 45
    • 33644688266 scopus 로고    scopus 로고
    • Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons
    • Vesce S, Jekabsons MB, Johnson-Cadwell LI, Nicholls DG (2005) Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J Biol Chem 280:38720-38728.
    • (2005) J Biol Chem , vol.280 , pp. 38720-38728
    • Vesce, S.1    Jekabsons, M.B.2    Johnson-Cadwell, L.I.3    Nicholls, D.G.4
  • 46
    • 0026522769 scopus 로고
    • Persisting modification of dendritic calcium influx by excitatory amino acid stimulation in isolated Ca1 neurons
    • Wadman WJ, Connor JA (1992) Persisting modification of dendritic calcium influx by excitatory amino acid stimulation in isolated Ca1 neurons. Neuroscience 48:293-305.
    • (1992) Neuroscience , vol.48 , pp. 293-305
    • Wadman, W.J.1    Connor, J.A.2
  • 47
    • 0027207494 scopus 로고
    • Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
    • Wahlestedt C, Golanov E, Yamamoto S, Yee F, Ericson H, Yoo H, Inturrisi CE, Reis DJ (1993) Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 363:260-263.
    • (1993) Nature , vol.363 , pp. 260-263
    • Wahlestedt, C.1    Golanov, E.2    Yamamoto, S.3    Yee, F.4    Ericson, H.5    Yoo, H.6    Inturrisi, C.E.7    Reis, D.J.8
  • 48
    • 0028988215 scopus 로고
    • Differential antagonism of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines
    • Wilding TJ, Huettner JE (1995) Differential antagonism of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines. Mol Pharmacol 47:582-587.
    • (1995) Mol Pharmacol , vol.47 , pp. 582-587
    • Wilding, T.J.1    Huettner, J.E.2
  • 49
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • Williams K (1993) Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44:851-859.
    • (1993) Mol Pharmacol , vol.44 , pp. 851-859
    • Williams, K.1
  • 50
    • 0025166425 scopus 로고
    • Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick
    • Yamaguchi K, Ohmori H (1990) Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick. J Physiol (Lond) 420:185-206.
    • (1990) J Physiol (Lond) , vol.420 , pp. 185-206
    • Yamaguchi, K.1    Ohmori, H.2
  • 51
    • 0033121301 scopus 로고    scopus 로고
    • 2+ release from mitochondria
    • 2+ release from mitochondria. J Neurosci 19:3307-3315.
    • (1999) J Neurosci , vol.19 , pp. 3307-3315
    • Zhang, Y.1    Lipton, P.2
  • 52
    • 33645010267 scopus 로고    scopus 로고
    • Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors
    • Zhou M, Baudry M (2006) Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J Neurosci 26:2956-2963.
    • (2006) J Neurosci , vol.26 , pp. 2956-2963
    • Zhou, M.1    Baudry, M.2


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