Insig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosis

International Journal of Cancer

Volumn 123, Issue 2, 2008, Pages 273-282

  Chang, Gong Li ^a   Gruidl, Mike ^a   Eschrich, Steven ^a   McCarthy, Susan ^a   Wang, Hong Gang ^a   Alexandrow, Mark G ^a   Yeatman, Timothy J ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Bax; Biomarker; Insig2; Mitochondria

Indexed keywords

BIOLOGICAL MARKER; PROTEIN BAX; COMPLEMENTARY DNA; CYTOCHROME C; INSIG2 PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL PEPTIDE; TUMOR MARKER;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; ARTICLE; CANCER SURVIVOR; CELL INVASION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLON CARCINOGENESIS; COLORECTAL CARCINOMA; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; INSULIN INDUCED GENE 2; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TUMOR GENE; UNIVARIATE ANALYSIS; COLON TUMOR; CONFOCAL MICROSCOPY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; IMMUNOPRECIPITATION; KAPLAN MEIER METHOD; METABOLISM; POLYMERASE CHAIN REACTION; PROTEIN MICROARRAY; RNA INTERFERENCE; SYNTHESIS; TUMOR CELL LINE; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYTOCHROMES C; DNA, COMPLEMENTARY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KAPLAN-MEIERS ESTIMATE; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; POLYMERASE CHAIN REACTION; PROTEIN ARRAY ANALYSIS; RNA INTERFERENCE; TUMOR MARKERS, BIOLOGICAL;

EID: 44949111329     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23510     Document Type: Article

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