메뉴 건너뛰기




Volumn 35, Issue 3, 2008, Pages 236-250

New Developments in Radiation Therapy for Head and Neck Cancer: Intensity-Modulated Radiation Therapy and Hypoxia Targeting

Author keywords

[No Author keywords available]

Indexed keywords

CARBOGEN; CARBOPLATIN; CISPLATIN; CYTOTOXIN; DINITROBENZAMIDE MUSTARD; ERYTHROPOIETIN; FLUOROURACIL; NICOTINAMIDE; NIMORAZOLE; NITROIMIDAZOLE DERIVATIVE; PR 104; TIRAPAZAMINE; TUMOR MARKER;

EID: 44649092578     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2008.03.003     Document Type: Article
Times cited : (43)

References (134)
  • 1
    • 0034985156 scopus 로고    scopus 로고
    • Inverse planning algorithms for external beam radiation therapy
    • Chui C.S., and Spirou S.V. Inverse planning algorithms for external beam radiation therapy. Med Dosimetry 26 (2001) 189-197
    • (2001) Med Dosimetry , vol.26 , pp. 189-197
    • Chui, C.S.1    Spirou, S.V.2
  • 2
    • 0035664146 scopus 로고    scopus 로고
    • Delivery of intensity-modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods
    • Chui C.S., Chan M.F., Yorke E., et al. Delivery of intensity-modulated radiation therapy with a conventional multileaf collimator: comparison of dynamic and segmental methods. Med Physics 28 (2001) 2441-2449
    • (2001) Med Physics , vol.28 , pp. 2441-2449
    • Chui, C.S.1    Chan, M.F.2    Yorke, E.3
  • 3
    • 0033828178 scopus 로고    scopus 로고
    • Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma
    • Xia P., Fu K.K., Wong G.W., et al. Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 48 (2000) 329-337
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 329-337
    • Xia, P.1    Fu, K.K.2    Wong, G.W.3
  • 4
    • 0037403119 scopus 로고    scopus 로고
    • Comparison of treatment plans using intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for paranasal sinus carcinoma
    • Huang D., Xia P., Akazawa P., et al. Comparison of treatment plans using intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for paranasal sinus carcinoma. Int J Radiat Oncol Biol Phys 56 (2003) 158-168
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 158-168
    • Huang, D.1    Xia, P.2    Akazawa, P.3
  • 5
    • 16644392902 scopus 로고    scopus 로고
    • Implementation of intensity-modulated radiation therapy in head and neck tumors: what are the important data for biological optimization?
    • Gregoire V. Implementation of intensity-modulated radiation therapy in head and neck tumors: what are the important data for biological optimization?. Rays 29 (2004) 271-274
    • (2004) Rays , vol.29 , pp. 271-274
    • Gregoire, V.1
  • 6
    • 0036868385 scopus 로고    scopus 로고
    • Dose conformation in IMRT for head and neck tumors: which solution to apply?
    • de Neve W., Duthoy W., Claus F., et al. Dose conformation in IMRT for head and neck tumors: which solution to apply?. Cancer Radiother 6 Suppl 1 (2002) 32s-36s
    • (2002) Cancer Radiother , vol.6 , Issue.SUPPL. 1
    • de Neve, W.1    Duthoy, W.2    Claus, F.3
  • 7
    • 0035400492 scopus 로고    scopus 로고
    • Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer
    • Eisbruch A., Kim H.M., Terrell J.E., et al. Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer. Int J Radiat Oncol Biol Phys 30 (2001) 695-704
    • (2001) Int J Radiat Oncol Biol Phys , vol.30 , pp. 695-704
    • Eisbruch, A.1    Kim, H.M.2    Terrell, J.E.3
  • 8
    • 0035869712 scopus 로고    scopus 로고
    • A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results
    • Chao K.S., Deasy J.O., Markman J., et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys 49 (2001) 907-916
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 907-916
    • Chao, K.S.1    Deasy, J.O.2    Markman, J.3
  • 9
    • 34548481328 scopus 로고    scopus 로고
    • Concurrent chemotherapy and intensity-modulated radiotherapy for locoregionally advanced laryngeal and hypopharyngeal cancers
    • Lee N.Y., O'Meara W., Chan K., et al. Concurrent chemotherapy and intensity-modulated radiotherapy for locoregionally advanced laryngeal and hypopharyngeal cancers. Int J Radiat Oncol Biol Phys (2007) 459-468
    • (2007) Int J Radiat Oncol Biol Phys , pp. 459-468
    • Lee, N.Y.1    O'Meara, W.2    Chan, K.3
  • 10
    • 0036569761 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience
    • Lee N., Xia P., Quivey J.M., et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience. Int J Radiat Oncol Biol Phys 53 (2002) 12-22
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 12-22
    • Lee, N.1    Xia, P.2    Quivey, J.M.3
  • 11
    • 0037297108 scopus 로고    scopus 로고
    • Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer
    • Chao K.S., Ozyigit G., Tran B.N., et al. Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 55 (2002) 312-321
    • (2002) Int J Radiat Oncol Biol Phys , vol.55 , pp. 312-321
    • Chao, K.S.1    Ozyigit, G.2    Tran, B.N.3
  • 12
    • 0041564120 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for head-and-neck cancer: the UCSF experience focusing on target volume delineation
    • Lee N., Xia P., Fischbein N.J., et al. Intensity-modulated radiation therapy for head-and-neck cancer: the UCSF experience focusing on target volume delineation. Int J Radiat Oncol Biol Phys 57 (2003) 49-60
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 49-60
    • Lee, N.1    Xia, P.2    Fischbein, N.J.3
  • 13
    • 0034653346 scopus 로고    scopus 로고
    • Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer
    • Dawson L.A., Anzai Y., Marsh L., et al. Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 46 (2000) 1117-1126
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 1117-1126
    • Dawson, L.A.1    Anzai, Y.2    Marsh, L.3
  • 14
    • 3242688903 scopus 로고    scopus 로고
    • CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines
    • Gregoire V., Levendag P., Ang K.K., et al. CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines. Radiother Oncol 69 (2003) 227-236
    • (2003) Radiother Oncol , vol.69 , pp. 227-236
    • Gregoire, V.1    Levendag, P.2    Ang, K.K.3
  • 15
    • 33646197680 scopus 로고    scopus 로고
    • Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck
    • Gregoire V., Eisbruch A., Hamoir M., et al. Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck. Radiother Oncol 79 (2006) 15-20
    • (2006) Radiother Oncol , vol.79 , pp. 15-20
    • Gregoire, V.1    Eisbruch, A.2    Hamoir, M.3
  • 16
    • 0035889335 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy: current status and issues of interest
    • Intensity Modulated Radiation Therapy Collaborative Working Group
    • Intensity Modulated Radiation Therapy Collaborative Working Group. Intensity-modulated radiotherapy: current status and issues of interest. Int J Radiat Oncol Biol Physics 51 (2001) 880-914
    • (2001) Int J Radiat Oncol Biol Physics , vol.51 , pp. 880-914
  • 17
    • 0035450631 scopus 로고    scopus 로고
    • Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90 Gy
    • Xia P., Pickett B., Vigneault E., et al. Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90 Gy. Int J Radiat Oncol Biol Phys 51 (2001) 244-254
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 244-254
    • Xia, P.1    Pickett, B.2    Vigneault, E.3
  • 18
    • 2442573854 scopus 로고    scopus 로고
    • Lee N, Akazawa C, Akazawa P, et al. A forward-planned treatment technique using multisegments in the treatment of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 59:584-94.
    • Lee N, Akazawa C, Akazawa P, et al. A forward-planned treatment technique using multisegments in the treatment of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 59:584-94.
  • 19
    • 2942553914 scopus 로고    scopus 로고
    • A study of planning dose constraints for treatment of nasopharyngeal carcinoma using a commercial inverse treatment planning system
    • Xia P., Lee N., Liu Y.M., et al. A study of planning dose constraints for treatment of nasopharyngeal carcinoma using a commercial inverse treatment planning system. Int J Radiat Oncol Biol Phys 59 (2004) 886-896
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 886-896
    • Xia, P.1    Lee, N.2    Liu, Y.M.3
  • 20
    • 0032972221 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy with dynamic multileaf collimators
    • Boyer A.L., and Yu C.X. Intensity-modulated radiation therapy with dynamic multileaf collimators. Semin Radiat Oncol 9 (1999) 48-59
    • (1999) Semin Radiat Oncol , vol.9 , pp. 48-59
    • Boyer, A.L.1    Yu, C.X.2
  • 21
    • 0035231532 scopus 로고    scopus 로고
    • Research Plan. 2002-2006. Image-Guided Radiation Therapy Committee
    • Radiation Therapy Oncology Group
    • Michalski J., Purdy J.A., Gaspar L., et al., Radiation Therapy Oncology Group. Research Plan. 2002-2006. Image-Guided Radiation Therapy Committee. Int J Radiat Oncol Biol Phys 51 (2001) 60-65
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 60-65
    • Michalski, J.1    Purdy, J.A.2    Gaspar, L.3
  • 22
    • 0035011160 scopus 로고    scopus 로고
    • Delivery systems of intensity-modulated radiotherapy using conventional multileaf collimators
    • Xia P., and Verhey L.J. Delivery systems of intensity-modulated radiotherapy using conventional multileaf collimators. Med Dosimetry 26 (2001) 169-177
    • (2001) Med Dosimetry , vol.26 , pp. 169-177
    • Xia, P.1    Verhey, L.J.2
  • 23
    • 34247211556 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy in head and neck cancers: an update
    • Lee N., Puri D.R., Blanco A.I., et al. Intensity-modulated radiation therapy in head and neck cancers: an update. Head Neck 29 (2007) 387-400
    • (2007) Head Neck , vol.29 , pp. 387-400
    • Lee, N.1    Puri, D.R.2    Blanco, A.I.3
  • 24
    • 0036570270 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy of head-and-neck cancer: encouraging early results
    • Eisbruch A. Intensity-modulated radiotherapy of head-and-neck cancer: encouraging early results. Int J Radiat Oncol Biol Phys 53 (2002) 1-3
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 1-3
    • Eisbruch, A.1
  • 25
    • 33847337952 scopus 로고    scopus 로고
    • Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
    • Daly M.E., Lieskovsky Y., Pawlicki T., et al. Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. Head Neck 29 (2007) 211-220
    • (2007) Head Neck , vol.29 , pp. 211-220
    • Daly, M.E.1    Lieskovsky, Y.2    Pawlicki, T.3
  • 26
    • 10044289431 scopus 로고    scopus 로고
    • Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?
    • Eisbruch A., Schwartz M., Rasch C., et al. Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?. Int J Radiat Oncol Biol Phys 60 (2004) 1425-1439
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 1425-1439
    • Eisbruch, A.1    Schwartz, M.2    Rasch, C.3
  • 27
    • 33750296383 scopus 로고    scopus 로고
    • A comparison of intensity-modulated radiation therapy and concomitant boost radiotherapy in the setting of concurrent chemotherapy for locally advanced oropharyngeal carcinoma
    • Lee N.Y., de Arruda F.F., Puri D.R., et al. A comparison of intensity-modulated radiation therapy and concomitant boost radiotherapy in the setting of concurrent chemotherapy for locally advanced oropharyngeal carcinoma. Int J Radiat Oncol Biol Phys 66 (2006) 966-974
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 966-974
    • Lee, N.Y.1    de Arruda, F.F.2    Puri, D.R.3
  • 28
    • 24944461129 scopus 로고    scopus 로고
    • Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma-the University of Iowa experience
    • Yao M., Dornfeld K.J., Buatti J.M., et al. Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma-the University of Iowa experience. Int J Radiat Oncol Biol Phys 63 (2005) 410-421
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 410-421
    • Yao, M.1    Dornfeld, K.J.2    Buatti, J.M.3
  • 29
    • 0037403225 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy in nasopharyngeal carcinoma: dosimetric advantage over conventional plans and feasibility of dose escalation
    • Kam M.K., Chau R.M., Suen J., et al. Intensity-modulated radiotherapy in nasopharyngeal carcinoma: dosimetric advantage over conventional plans and feasibility of dose escalation. Int J Radiat Oncol Biol Phys 56 (2003) 145-157
    • (2003) Int J Radiat Oncol Biol Phys , vol.56 , pp. 145-157
    • Kam, M.K.1    Chau, R.M.2    Suen, J.3
  • 30
    • 20244364349 scopus 로고    scopus 로고
    • Treatment planning and delivery of intensity-modulated radiation therapy for primary nasopharynx cancer
    • Hunt M.A., Zelefsky M.J., Wolden S., et al. Treatment planning and delivery of intensity-modulated radiation therapy for primary nasopharynx cancer. Int J Radiat Oncol Biol Phys 49 (2001) 623-632
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 623-632
    • Hunt, M.A.1    Zelefsky, M.J.2    Wolden, S.3
  • 31
    • 4844223514 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: a prospective study on disease control and preservation of salivary function
    • Kwong D.L., Pow E.H., Sham J.S., et al. Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: a prospective study on disease control and preservation of salivary function. Cancer 101 (2004) 1584-1593
    • (2004) Cancer , vol.101 , pp. 1584-1593
    • Kwong, D.L.1    Pow, E.H.2    Sham, J.S.3
  • 32
    • 10044257645 scopus 로고    scopus 로고
    • Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience
    • Kam M.K., Teo P.M., Chau R.M., et al. Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience. Int J Radiat Oncol Biol Phys 60 (2004) 1440-1450
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 1440-1450
    • Kam, M.K.1    Teo, P.M.2    Chau, R.M.3
  • 33
    • 29244459121 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: update of the Memorial Sloan-Kettering experience
    • Wolden S.L., Chen W.C., Pfister D.G., et al. Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: update of the Memorial Sloan-Kettering experience. Int J Radiat Oncol Biol Phys 64 (2006) 57-62
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 57-62
    • Wolden, S.L.1    Chen, W.C.2    Pfister, D.G.3
  • 34
    • 36849010786 scopus 로고    scopus 로고
    • Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients
    • Kam M.K.M., Leung S.-F., Zee B., et al. Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients. J Clin Oncol 25 (2007) 4873-4879
    • (2007) J Clin Oncol , vol.25 , pp. 4873-4879
    • Kam, M.K.M.1    Leung, S.-F.2    Zee, B.3
  • 35
    • 14944364187 scopus 로고    scopus 로고
    • Intensity modulated radiation therapy for carcinoma of the nasopharynx: an update of the UCSF experience
    • Bucci M., Xia P., Lee N., et al. Intensity modulated radiation therapy for carcinoma of the nasopharynx: an update of the UCSF experience. Int J Radiat Oncol Biol Phys 60 (2004) 317-318
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 317-318
    • Bucci, M.1    Xia, P.2    Lee, N.3
  • 36
    • 14644411058 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial growth factor immunohistochemical expression in head and neck squamous cell carcinoma: a meta-analysis
    • Kyzas P.A., Cunha I.W., and Ioannidis J.P. Prognostic significance of vascular endothelial growth factor immunohistochemical expression in head and neck squamous cell carcinoma: a meta-analysis. Clin Cancer Res 11 (2005) 1434-1440
    • (2005) Clin Cancer Res , vol.11 , pp. 1434-1440
    • Kyzas, P.A.1    Cunha, I.W.2    Ioannidis, J.P.3
  • 37
    • 0034650190 scopus 로고    scopus 로고
    • Elevation of serum vascular endothelial growth factor in male patients with metastatic nasopharyngeal carcinoma
    • Qian C.N., Zhang C.Q., Guo X., et al. Elevation of serum vascular endothelial growth factor in male patients with metastatic nasopharyngeal carcinoma. Cancer 88 (2000) 255-261
    • (2000) Cancer , vol.88 , pp. 255-261
    • Qian, C.N.1    Zhang, C.Q.2    Guo, X.3
  • 38
    • 28844480928 scopus 로고    scopus 로고
    • Expression of VEGF as prognosticator in primary nasopharyngeal cancer and its relation to EBV status
    • Krishna S.M., James S., and Balaram P. Expression of VEGF as prognosticator in primary nasopharyngeal cancer and its relation to EBV status. Virus Res 115 (2006) 85-90
    • (2006) Virus Res , vol.115 , pp. 85-90
    • Krishna, S.M.1    James, S.2    Balaram, P.3
  • 39
    • 0042566199 scopus 로고    scopus 로고
    • Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study
    • Lin A., Kim H.M., Terrell J.E., et al. Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study. Int J Radiat Oncol Biol Phys 57 (2003) 61-70
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , pp. 61-70
    • Lin, A.1    Kim, H.M.2    Terrell, J.E.3
  • 40
    • 10044286277 scopus 로고    scopus 로고
    • Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing
    • Eisbruch A., Marsh L.H., Dawson L.A., et al. Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing. Int J Radiat Oncol Biol Phys 59 (2004) 28-42
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 28-42
    • Eisbruch, A.1    Marsh, L.H.2    Dawson, L.A.3
  • 41
    • 13244269447 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for oropharyngeal carcinoma: impact of tumor volume
    • Chao K.S., Ozyigit G., Blanco A.I., et al. Intensity-modulated radiation therapy for oropharyngeal carcinoma: impact of tumor volume. Int J Radiat Oncol Biol Phys 59 (2004) 43-50
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , pp. 43-50
    • Chao, K.S.1    Ozyigit, G.2    Blanco, A.I.3
  • 42
    • 30544450734 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for the treatment of oropharyngeal carcinoma: the Memorial Sloan-Kettering Cancer Center experience
    • de Arruda F.F., Puri D.R., Zhung J., et al. Intensity-modulated radiation therapy for the treatment of oropharyngeal carcinoma: the Memorial Sloan-Kettering Cancer Center experience. Int J Radiat Oncol Biol Phys 64 (2006) 363-373
    • (2006) Int J Radiat Oncol Biol Phys , vol.64 , pp. 363-373
    • de Arruda, F.F.1    Puri, D.R.2    Zhung, J.3
  • 44
    • 0345714860 scopus 로고    scopus 로고
    • Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer
    • Forastiere A.A., Goepfert H., Maor M., et al. Concurrent chemotherapy and radiotherapy for organ preservation in advanced laryngeal cancer. N Engl J Med 349 (2003) 2091-2098
    • (2003) N Engl J Med , vol.349 , pp. 2091-2098
    • Forastiere, A.A.1    Goepfert, H.2    Maor, M.3
  • 45
    • 34248334126 scopus 로고    scopus 로고
    • Intensity modulated radiotherapy (IMRT) in patients with carcinomas of the paranasal sinuses: clinical benefit for complex shaped target volumes
    • Combs S.E., Konkel S., Schulz-Ertner D., et al. Intensity modulated radiotherapy (IMRT) in patients with carcinomas of the paranasal sinuses: clinical benefit for complex shaped target volumes. Radiat Oncol 1 (2006) 23
    • (2006) Radiat Oncol , vol.1 , pp. 23
    • Combs, S.E.1    Konkel, S.2    Schulz-Ertner, D.3
  • 46
    • 0036792451 scopus 로고    scopus 로고
    • Report of a study on IMRT planning strategies for ethmoid sinus cancer
    • Claus F., Mijnheer B., Rasch C., et al. Report of a study on IMRT planning strategies for ethmoid sinus cancer. Strahlenther Onkol 178 (2002) 572-576
    • (2002) Strahlenther Onkol , vol.178 , pp. 572-576
    • Claus, F.1    Mijnheer, B.2    Rasch, C.3
  • 47
    • 33846794458 scopus 로고    scopus 로고
    • Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting-the MSKCC experience
    • Hoppe B.S., Stegman L.D., Zelefsky M.J., et al. Treatment of nasal cavity and paranasal sinus cancer with modern radiotherapy techniques in the postoperative setting-the MSKCC experience. Int J Radiat Oncol Biol Phys 67 (2007) 691-702
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 691-702
    • Hoppe, B.S.1    Stegman, L.D.2    Zelefsky, M.J.3
  • 48
    • 33845609622 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses
    • Daly M.E., Chen A.M., Bucci M.K., et al. Intensity-modulated radiation therapy for malignancies of the nasal cavity and paranasal sinuses. Int J Radiat Oncol Biol Phys 67 (2007) 151-157
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 151-157
    • Daly, M.E.1    Chen, A.M.2    Bucci, M.K.3
  • 49
    • 0036669633 scopus 로고    scopus 로고
    • Short term toxicity profile for 32 sinonasal cancer patients treated with IMRT. Can we avoid dry eye syndrome?
    • Claus F., Boterberg T., Ost P., et al. Short term toxicity profile for 32 sinonasal cancer patients treated with IMRT. Can we avoid dry eye syndrome?. Radiother Oncol 64 (2002) 205-208
    • (2002) Radiother Oncol , vol.64 , pp. 205-208
    • Claus, F.1    Boterberg, T.2    Ost, P.3
  • 50
    • 33845609622 scopus 로고    scopus 로고
    • Carcinomas of the paranasal sinuses and nasal cavity treated with radiotherapy at a single institution over five decades: are we making improvement?
    • Chen A.M., Daly M.E., Bucci M.K., et al. Carcinomas of the paranasal sinuses and nasal cavity treated with radiotherapy at a single institution over five decades: are we making improvement?. Int J Radiat Oncol Biol Phys 67 (2007) 151-157
    • (2007) Int J Radiat Oncol Biol Phys , vol.67 , pp. 151-157
    • Chen, A.M.1    Daly, M.E.2    Bucci, M.K.3
  • 51
    • 0034962347 scopus 로고    scopus 로고
    • Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid gland
    • Nutting C.M., Convery D.J., Cosgrove V.P., et al. Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid gland. Radiother Oncol 60 (2001) 173-180
    • (2001) Radiother Oncol , vol.60 , pp. 173-180
    • Nutting, C.M.1    Convery, D.J.2    Cosgrove, V.P.3
  • 52
    • 0034264595 scopus 로고    scopus 로고
    • Dose optimization for the treatment of anaplastic thyroid carcinoma: a comparison of treatment planning techniques
    • Posner M.D., Quivey J.M., Akazawa P.F., et al. Dose optimization for the treatment of anaplastic thyroid carcinoma: a comparison of treatment planning techniques. Int J Radiat Oncol Biol Phys 48 (2000) 475-483
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 475-483
    • Posner, M.D.1    Quivey, J.M.2    Akazawa, P.F.3
  • 53
    • 27744562123 scopus 로고    scopus 로고
    • Intensity-modulated radiation therapy for the treatment of non-anaplastic thyroid cancer
    • Rosenbluth B.D., Serrano V., Hunt M.A., et al. Intensity-modulated radiation therapy for the treatment of non-anaplastic thyroid cancer. Int J Radiat Oncol Biol Phys 63 (2005) 1419-1426
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 1419-1426
    • Rosenbluth, B.D.1    Serrano, V.2    Hunt, M.A.3
  • 54
    • 0035987855 scopus 로고    scopus 로고
    • Intensity-modulated radiotherapy for previously irradiated, recurrent head-and-neck cancer
    • Chen Y.J., Kuo J.V., Ramsinghani N.S., et al. Intensity-modulated radiotherapy for previously irradiated, recurrent head-and-neck cancer. Med Dosimetry 27 (2002) 171-176
    • (2002) Med Dosimetry , vol.27 , pp. 171-176
    • Chen, Y.J.1    Kuo, J.V.2    Ramsinghani, N.S.3
  • 55
    • 10744224743 scopus 로고    scopus 로고
    • Initial experience using intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma
    • Lu T.X., Mai W.Y., Teh B.S., et al. Initial experience using intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 58 (2004) 682-687
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 682-687
    • Lu, T.X.1    Mai, W.Y.2    Teh, B.S.3
  • 56
    • 34249340144 scopus 로고    scopus 로고
    • Salvage re-irradiation for recurrent head and neck cancer
    • Lee N., Chan K., Bekelman J.E., et al. Salvage re-irradiation for recurrent head and neck cancer. Int J Radiat Oncol Biol Phys 68 (2007) 731-740
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 731-740
    • Lee, N.1    Chan, K.2    Bekelman, J.E.3
  • 57
    • 33751543273 scopus 로고    scopus 로고
    • Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy
    • Tatum J.L., Kelloff G.J., Gillies R.J., et al. Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy. Int J Radiat Biol 82 (2006) 699-757
    • (2006) Int J Radiat Biol , vol.82 , pp. 699-757
    • Tatum, J.L.1    Kelloff, G.J.2    Gillies, R.J.3
  • 58
    • 0023932431 scopus 로고
    • Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy
    • Gatenby R.A., Kessler H.B., Rosenblum J.S., et al. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 14 (1988) 831-838
    • (1988) Int J Radiat Oncol Biol Phys , vol.14 , pp. 831-838
    • Gatenby, R.A.1    Kessler, H.B.2    Rosenblum, J.S.3
  • 59
    • 0021701786 scopus 로고
    • Heterogeneous oxygenation of rectal carcinomas in humans: a critical parameter for preoperative irradiation?
    • Wendling P., Manz R., Thews G., et al. Heterogeneous oxygenation of rectal carcinomas in humans: a critical parameter for preoperative irradiation?. Adv Exp Med Biol 180 (1984) 293-300
    • (1984) Adv Exp Med Biol , vol.180 , pp. 293-300
    • Wendling, P.1    Manz, R.2    Thews, G.3
  • 60
    • 0032708195 scopus 로고    scopus 로고
    • Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome
    • Brizel D.M., Dodge R.K., Clough R.W., et al. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome. Radiother Oncol 53 (1999) 113-117
    • (1999) Radiother Oncol , vol.53 , pp. 113-117
    • Brizel, D.M.1    Dodge, R.K.2    Clough, R.W.3
  • 61
    • 0034307112 scopus 로고    scopus 로고
    • A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy
    • Nordsmark M., and Overgaard J. A confirmatory prognostic study on oxygenation status and loco-regional control in advanced head and neck squamous cell carcinoma treated by radiation therapy. Radiother Oncol 57 (2000) 39-43
    • (2000) Radiother Oncol , vol.57 , pp. 39-43
    • Nordsmark, M.1    Overgaard, J.2
  • 62
    • 0034819345 scopus 로고    scopus 로고
    • Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer
    • Rudat V., Stadler P., Becker A., et al. Predictive value of the tumor oxygenation by means of pO2 histography in patients with advanced head and neck cancer. Strahlenther Onkol 177 (2001) 462-468
    • (2001) Strahlenther Onkol , vol.177 , pp. 462-468
    • Rudat, V.1    Stadler, P.2    Becker, A.3
  • 63
    • 1842476892 scopus 로고    scopus 로고
    • Necessity for adjuvant neck dissection in setting of concurrent chemoradiation for advanced head-and-neck cancer
    • Brizel D.M., Prosnitz R.G., Hunter S., et al. Necessity for adjuvant neck dissection in setting of concurrent chemoradiation for advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 58 (2004) 1418-1423
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 1418-1423
    • Brizel, D.M.1    Prosnitz, R.G.2    Hunter, S.3
  • 64
    • 26444466467 scopus 로고    scopus 로고
    • Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study
    • Nordsmark M., Bentzen S.M., Rudat V., et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother Oncol 77 (2005) 18-24
    • (2005) Radiother Oncol , vol.77 , pp. 18-24
    • Nordsmark, M.1    Bentzen, S.M.2    Rudat, V.3
  • 65
    • 0027141149 scopus 로고
    • Oxygen in human tumors: correlations between methods of measurement and response to therapy
    • Stone H.B., Brown J.M., Phillips T.L., et al. Oxygen in human tumors: correlations between methods of measurement and response to therapy. Radiat Res 136 (1993) 422-434
    • (1993) Radiat Res , vol.136 , pp. 422-434
    • Stone, H.B.1    Brown, J.M.2    Phillips, T.L.3
  • 66
    • 0032170012 scopus 로고    scopus 로고
    • Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker
    • Raleigh J.A., Calkins-Adams D.P., Rinker L.H., et al. Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res 58 (1998) 3765-3768
    • (1998) Cancer Res , vol.58 , pp. 3765-3768
    • Raleigh, J.A.1    Calkins-Adams, D.P.2    Rinker, L.H.3
  • 67
    • 0034029848 scopus 로고    scopus 로고
    • Detection of hypoxia in human squamous cell carcinoma by EF5 binding
    • Evans S.M., Hahn S., Pook D.R., et al. Detection of hypoxia in human squamous cell carcinoma by EF5 binding. Cancer Res 60 (2000) 2018-2024
    • (2000) Cancer Res , vol.60 , pp. 2018-2024
    • Evans, S.M.1    Hahn, S.2    Pook, D.R.3
  • 68
    • 0017089008 scopus 로고
    • Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo
    • Varghese A.J., Gulyas S., and Mohindra J.K. Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo. Cancer Res 36 (1976) 3761-3765
    • (1976) Cancer Res , vol.36 , pp. 3761-3765
    • Varghese, A.J.1    Gulyas, S.2    Mohindra, J.K.3
  • 69
    • 33846850493 scopus 로고    scopus 로고
    • Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers
    • Ljungkvist A.S., Bussink J., Kaanders J.H., et al. Dynamics of tumor hypoxia measured with bioreductive hypoxic cell markers. Radiat Res 167 (2007) 127-145
    • (2007) Radiat Res , vol.167 , pp. 127-145
    • Ljungkvist, A.S.1    Bussink, J.2    Kaanders, J.H.3
  • 70
    • 0038293080 scopus 로고    scopus 로고
    • Prognostic significance of tumor oxygenation in humans
    • Evans S.M., and Koch C.J. Prognostic significance of tumor oxygenation in humans. Cancer Lett 195 (2003) 1-16
    • (2003) Cancer Lett , vol.195 , pp. 1-16
    • Evans, S.M.1    Koch, C.J.2
  • 71
    • 0032801526 scopus 로고    scopus 로고
    • Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors
    • Raleigh J.A., Chou S.C., Arteel G.E., et al. Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. Radiat Res 151 (1999) 580-589
    • (1999) Radiat Res , vol.151 , pp. 580-589
    • Raleigh, J.A.1    Chou, S.C.2    Arteel, G.E.3
  • 72
    • 0036896722 scopus 로고    scopus 로고
    • Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer
    • Kaanders J.H., Wijffels K.I., Marres H.A., et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res 62 (2002) 7066-7074
    • (2002) Cancer Res , vol.62 , pp. 7066-7074
    • Kaanders, J.H.1    Wijffels, K.I.2    Marres, H.A.3
  • 73
    • 0035159670 scopus 로고    scopus 로고
    • HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
    • Stroka D.M., Burkhardt T., Desbaillets I., et al. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 15 (2001) 2445-2453
    • (2001) FASEB J , vol.15 , pp. 2445-2453
    • Stroka, D.M.1    Burkhardt, T.2    Desbaillets, I.3
  • 74
    • 0034050050 scopus 로고    scopus 로고
    • Loss of PTEN facilitates HIF-1-mediated gene expression
    • Zundel W., Schindler C., Haas-Kogan D., et al. Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev 14 (2000) 391-396
    • (2000) Genes Dev , vol.14 , pp. 391-396
    • Zundel, W.1    Schindler, C.2    Haas-Kogan, D.3
  • 75
    • 0032169214 scopus 로고    scopus 로고
    • Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT
    • Zelzer E., Levy Y., Kahana C., et al. Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT. EMBO J 17 (1998) 5085-5094
    • (1998) EMBO J , vol.17 , pp. 5085-5094
    • Zelzer, E.1    Levy, Y.2    Kahana, C.3
  • 76
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics
    • Zhong H., Chiles K., Feldser D., et al. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60 (2000) 1541-1545
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3
  • 77
    • 0036883983 scopus 로고    scopus 로고
    • HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors
    • Janssen H.L., Haustermans K.M., Sprong D., et al. HIF-1A, pimonidazole, and iododeoxyuridine to estimate hypoxia and perfusion in human head-and-neck tumors. Int J Radiat Oncol Biol Phys 54 (2002) 1537-1549
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 1537-1549
    • Janssen, H.L.1    Haustermans, K.M.2    Sprong, D.3
  • 78
    • 33644551073 scopus 로고    scopus 로고
    • Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    • Chi J.T., Wang Z., Nuyten D.S., et al. Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. PLoS Med 3 (2006) e47
    • (2006) PLoS Med , vol.3
    • Chi, J.T.1    Wang, Z.2    Nuyten, D.S.3
  • 79
    • 34248172298 scopus 로고    scopus 로고
    • Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers
    • Winter S.C., Buffa F.M., Silva P., et al. Relation of a hypoxia metagene derived from head and neck cancer to prognosis of multiple cancers. Cancer Res 67 (2007) 3441-3449
    • (2007) Cancer Res , vol.67 , pp. 3441-3449
    • Winter, S.C.1    Buffa, F.M.2    Silva, P.3
  • 80
    • 34547842084 scopus 로고    scopus 로고
    • Expression and prognostic significance of a panel of tissue hypoxia markers in head and neck squamous cell carcinomas
    • Le Q.T., Kong C., Lavori P.W., et al. Expression and prognostic significance of a panel of tissue hypoxia markers in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 69 (2007) 167-175
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 167-175
    • Le, Q.T.1    Kong, C.2    Lavori, P.W.3
  • 81
    • 0033865941 scopus 로고    scopus 로고
    • Serum levels of vascular endothelial growth factor in patients with head and neck cancer
    • Riedel F., Gotte K., Schwalb J., et al. Serum levels of vascular endothelial growth factor in patients with head and neck cancer. Eur Arch Otorhinolaryngol 257 (2000) 332-336
    • (2000) Eur Arch Otorhinolaryngol , vol.257 , pp. 332-336
    • Riedel, F.1    Gotte, K.2    Schwalb, J.3
  • 82
    • 1842409593 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor is often elevated in disseminated cancer
    • Salven P., Manpaa H., Orpana A., et al. Serum vascular endothelial growth factor is often elevated in disseminated cancer. Clin Cancer Res 3 (1997) 647-651
    • (1997) Clin Cancer Res , vol.3 , pp. 647-651
    • Salven, P.1    Manpaa, H.2    Orpana, A.3
  • 83
    • 0035883079 scopus 로고    scopus 로고
    • Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea-hypopnea syndrome
    • Imagawa S., Yamaguchi Y., Higuchi M., et al. Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea-hypopnea syndrome. Blood 98 (2001) 1255-1257
    • (2001) Blood , vol.98 , pp. 1255-1257
    • Imagawa, S.1    Yamaguchi, Y.2    Higuchi, M.3
  • 84
    • 0034832179 scopus 로고    scopus 로고
    • Tumor hypoxia and systemic levels of vascular endothelial growth factor (VEGF) in head and neck cancers
    • Dunst J., Stadler P., Becker A., et al. Tumor hypoxia and systemic levels of vascular endothelial growth factor (VEGF) in head and neck cancers. Strahlenther Onkol 177 (2001) 469-473
    • (2001) Strahlenther Onkol , vol.177 , pp. 469-473
    • Dunst, J.1    Stadler, P.2    Becker, A.3
  • 85
    • 12244267969 scopus 로고    scopus 로고
    • Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
    • Le Q.T., Sutphin P.D., Raychaudhuri S., et al. Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clin Cancer Res 9 (2003) 59-67
    • (2003) Clin Cancer Res , vol.9 , pp. 59-67
    • Le, Q.T.1    Sutphin, P.D.2    Raychaudhuri, S.3
  • 86
    • 34250166555 scopus 로고    scopus 로고
    • Differential risk assessments from five hypoxia specific assays: the basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients
    • Nordsmark M., Eriksen J.G., Gebski V., et al. Differential risk assessments from five hypoxia specific assays: the basis for biologically adapted individualized radiotherapy in advanced head and neck cancer patients. Radiother Oncol (2007)
    • (2007) Radiother Oncol
    • Nordsmark, M.1    Eriksen, J.G.2    Gebski, V.3
  • 87
    • 34247346481 scopus 로고    scopus 로고
    • Plasma osteopontin is an independent prognostic marker for head and neck cancers
    • Petrik D., Lavori P.W., Cao H., et al. Plasma osteopontin is an independent prognostic marker for head and neck cancers. J Clin Oncol 24 (2006) 5291-5297
    • (2006) J Clin Oncol , vol.24 , pp. 5291-5297
    • Petrik, D.1    Lavori, P.W.2    Cao, H.3
  • 88
    • 26444467146 scopus 로고    scopus 로고
    • Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial
    • Overgaard J., Eriksen J.G., Nordsmark M., et al. Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 6 (2005) 757-764
    • (2005) Lancet Oncol , vol.6 , pp. 757-764
    • Overgaard, J.1    Eriksen, J.G.2    Nordsmark, M.3
  • 89
    • 0030069889 scopus 로고    scopus 로고
    • Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers
    • Overgaard J., and Horsman M.R. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol 6 (1996) 10-21
    • (1996) Semin Radiat Oncol , vol.6 , pp. 10-21
    • Overgaard, J.1    Horsman, M.R.2
  • 90
    • 0018123111 scopus 로고
    • Hyperbaric oxygen and radiotherapy: a Medical Research Council trial in carcinoma of the cervix
    • Watson E.R., Halnan K.E., Dische S., et al. Hyperbaric oxygen and radiotherapy: a Medical Research Council trial in carcinoma of the cervix. Br J Radiol 51 (1978) 879-887
    • (1978) Br J Radiol , vol.51 , pp. 879-887
    • Watson, E.R.1    Halnan, K.E.2    Dische, S.3
  • 91
    • 0020608102 scopus 로고
    • Carcinoma of the cervix-anaemia, radiotherapy and hyperbaric oxygen
    • Dische S., Anderson P.J., Sealy R., et al. Carcinoma of the cervix-anaemia, radiotherapy and hyperbaric oxygen. Br J Radiol 56 (1983) 251-255
    • (1983) Br J Radiol , vol.56 , pp. 251-255
    • Dische, S.1    Anderson, P.J.2    Sealy, R.3
  • 92
    • 0016353701 scopus 로고
    • Radiosensitization of C3H mouse mammary tumours by a 2-nitroimidazole drug
    • Sheldon P.W., Foster J.L., and Fowler J.F. Radiosensitization of C3H mouse mammary tumours by a 2-nitroimidazole drug. Br J Cancer 30 (1974) 560-565
    • (1974) Br J Cancer , vol.30 , pp. 560-565
    • Sheldon, P.W.1    Foster, J.L.2    Fowler, J.F.3
  • 93
    • 0016587704 scopus 로고
    • Selective radiosensitization of the hypoxic cells of mouse tumors with the nitroimidazoles metronidazole and Ro 7-0582
    • Brown J.M. Selective radiosensitization of the hypoxic cells of mouse tumors with the nitroimidazoles metronidazole and Ro 7-0582. Radiat Res 64 (1975) 633-647
    • (1975) Radiat Res , vol.64 , pp. 633-647
    • Brown, J.M.1
  • 94
    • 0024504773 scopus 로고
    • A phase I/II study of the hypoxic cell sensitizer misonidazole as an adjunct to high fractional dose radiotherapy in patients with unresectable squamous cell carcinoma of the head and neck: a RTOG randomized study (#79-04)
    • Lee D.J., Pajak T.F., Stetz J., et al. A phase I/II study of the hypoxic cell sensitizer misonidazole as an adjunct to high fractional dose radiotherapy in patients with unresectable squamous cell carcinoma of the head and neck: a RTOG randomized study (#79-04). Int J Radiat Oncol Biol Phys 16 (1989) 465-470
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 465-470
    • Lee, D.J.1    Pajak, T.F.2    Stetz, J.3
  • 95
    • 0029066473 scopus 로고
    • Results of an RTOG phase III trial (RTOG 85-27) comparing radiotherapy plus etanidazole with radiotherapy alone for locally advanced head and neck carcinomas
    • Lee D.J., Cosmatos D., Marcial V.A., et al. Results of an RTOG phase III trial (RTOG 85-27) comparing radiotherapy plus etanidazole with radiotherapy alone for locally advanced head and neck carcinomas. Int J Radiat Oncol Biol Phys 32 (1995) 567-576
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 567-576
    • Lee, D.J.1    Cosmatos, D.2    Marcial, V.A.3
  • 96
    • 0024384825 scopus 로고
    • Misonidazole combined with split course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA study
    • Overgaard J., Hansen H.S., Anderson A.P., et al. Misonidazole combined with split course radiotherapy in the treatment of invasive carcinoma of larynx and pharynx: report from the DAHANCA study. Int J Radiat Oncol Biol Phys 16 (1989) 1065-1068
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1065-1068
    • Overgaard, J.1    Hansen, H.S.2    Anderson, A.P.3
  • 97
    • 0031909654 scopus 로고    scopus 로고
    • A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85
    • Overgaard J., Hansen H.S., Overgaard M., et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85. Radiother Oncol 46 (1998) 135-146
    • (1998) Radiother Oncol , vol.46 , pp. 135-146
    • Overgaard, J.1    Hansen, H.S.2    Overgaard, M.3
  • 98
    • 0026077993 scopus 로고
    • Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG)
    • Wasserman T.H., Lee D.J., Cosmatos D., et al. Clinical trials with etanidazole (SR-2508) by the Radiation Therapy Oncology Group (RTOG). Radiother Oncol 20 Suppl 1 (1991) 129-135
    • (1991) Radiother Oncol , vol.20 , Issue.SUPPL. 1 , pp. 129-135
    • Wasserman, T.H.1    Lee, D.J.2    Cosmatos, D.3
  • 99
    • 0017388874 scopus 로고
    • Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses
    • Dische S., Saunders M.I., Lee M.E., et al. Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses. Br J Cancer 35 (1977) 567-579
    • (1977) Br J Cancer , vol.35 , pp. 567-579
    • Dische, S.1    Saunders, M.I.2    Lee, M.E.3
  • 100
    • 0022490339 scopus 로고
    • Phase I trial of the hypoxic cell radiosensitizer SR-2508: the results of the five to six week drug schedule
    • Coleman C.N., Wasserman T.H., Urtasun R.C., et al. Phase I trial of the hypoxic cell radiosensitizer SR-2508: the results of the five to six week drug schedule. Int J Radiat Oncol Biol Phys 12 (1986) 1105-1108
    • (1986) Int J Radiat Oncol Biol Phys , vol.12 , pp. 1105-1108
    • Coleman, C.N.1    Wasserman, T.H.2    Urtasun, R.C.3
  • 101
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial
    • Henke M., Laszig R., Rube C., et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet 362 (2003) 1255-1260
    • (2003) Lancet , vol.362 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3
  • 102
    • 33750588816 scopus 로고    scopus 로고
    • Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    • Henke M., Mattern D., Pepe M., et al. Do erythropoietin receptors on cancer cells explain unexpected clinical findings?. J Clin Oncol 24 (2006) 4708-4713
    • (2006) J Clin Oncol , vol.24 , pp. 4708-4713
    • Henke, M.1    Mattern, D.2    Pepe, M.3
  • 103
    • 11844254414 scopus 로고    scopus 로고
    • Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
    • Jain R.K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307 (2005) 58-62
    • (2005) Science , vol.307 , pp. 58-62
    • Jain, R.K.1
  • 104
    • 11144354392 scopus 로고    scopus 로고
    • Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
    • Willett C.G., Boucher Y., di Tomaso E., et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 10 (2004) 145-147
    • (2004) Nat Med , vol.10 , pp. 145-147
    • Willett, C.G.1    Boucher, Y.2    di Tomaso, E.3
  • 105
    • 20144373280 scopus 로고    scopus 로고
    • Paclitaxel decreases the interstitial fluid pressure and improves oxygenation in breast cancers in patients treated with neoadjuvant chemotherapy: clinical implications
    • Taghian A.G., Abi-Raad R., Assaad S.I., et al. Paclitaxel decreases the interstitial fluid pressure and improves oxygenation in breast cancers in patients treated with neoadjuvant chemotherapy: clinical implications. J Clin Oncol 23 (2005) 1951-1961
    • (2005) J Clin Oncol , vol.23 , pp. 1951-1961
    • Taghian, A.G.1    Abi-Raad, R.2    Assaad, S.I.3
  • 106
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor T.T., Sorensen A.G., di Tomaso E., et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11 (2007) 83-95
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    di Tomaso, E.3
  • 107
    • 0036498885 scopus 로고    scopus 로고
    • ARCON: experience in 215 patients with advanced head-and-neck cancer
    • Kaanders J.H., Pop L.A., Marres H.A., et al. ARCON: experience in 215 patients with advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 52 (2002) 769-778
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 769-778
    • Kaanders, J.H.1    Pop, L.A.2    Marres, H.A.3
  • 108
    • 0031032568 scopus 로고    scopus 로고
    • Chemotherapy as an adjunct to radiation in the treatment of squamous cell carcinoma of the head and neck: results of the Yale Mitomycin Randomized Trials
    • Haffty B.G., Son Y.H., Papac R., et al. Chemotherapy as an adjunct to radiation in the treatment of squamous cell carcinoma of the head and neck: results of the Yale Mitomycin Randomized Trials. J Clin Oncol 15 (1997) 268-276
    • (1997) J Clin Oncol , vol.15 , pp. 268-276
    • Haffty, B.G.1    Son, Y.H.2    Papac, R.3
  • 109
    • 0031597441 scopus 로고    scopus 로고
    • Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancer
    • Dobrowsky W., Naude J., Widder J., et al. Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancer. Int J Radiat Oncol Biol Phys 42 (1998) 803-806
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , pp. 803-806
    • Dobrowsky, W.1    Naude, J.2    Widder, J.3
  • 110
    • 0034332792 scopus 로고    scopus 로고
    • Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers
    • Dobrowsky W., and Naude J. Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers. Radiother Oncol 57 (2000) 119-124
    • (2000) Radiother Oncol , vol.57 , pp. 119-124
    • Dobrowsky, W.1    Naude, J.2
  • 111
    • 16644377045 scopus 로고    scopus 로고
    • Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: a randomized phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02)
    • Rischin D., Peters L., Fisher R., et al. Tirapazamine, cisplatin, and radiation versus fluorouracil, cisplatin, and radiation in patients with locally advanced head and neck cancer: a randomized phase II trial of the Trans-Tasman Radiation Oncology Group (TROG 98.02). J Clin Oncol 23 (2005) 79-87
    • (2005) J Clin Oncol , vol.23 , pp. 79-87
    • Rischin, D.1    Peters, L.2    Fisher, R.3
  • 112
    • 33646353445 scopus 로고    scopus 로고
    • Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas
    • Le Q.T., Taira A., Budenz S., et al. Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas. Cancer 106 (2006) 1940-1949
    • (2006) Cancer , vol.106 , pp. 1940-1949
    • Le, Q.T.1    Taira, A.2    Budenz, S.3
  • 113
    • 33947621321 scopus 로고    scopus 로고
    • Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards
    • Wilson W.R., Hicks K.O., Pullen S.M., et al. Bystander effects of bioreductive drugs: potential for exploiting pathological tumor hypoxia with dinitrobenzamide mustards. Radiat Res 167 (2007) 625-636
    • (2007) Radiat Res , vol.167 , pp. 625-636
    • Wilson, W.R.1    Hicks, K.O.2    Pullen, S.M.3
  • 114
    • 34447122556 scopus 로고    scopus 로고
    • Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA crosslinking agent PR-104
    • Patterson A.V., Ferry D.M., Edmunds S.J., et al. Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA crosslinking agent PR-104. Clin Cancer Res 13 (2007) 3922-3932
    • (2007) Clin Cancer Res , vol.13 , pp. 3922-3932
    • Patterson, A.V.1    Ferry, D.M.2    Edmunds, S.J.3
  • 116
    • 34547098129 scopus 로고    scopus 로고
    • Targeting hypoxia cell signaling for cancer therapy
    • Melillo G. Targeting hypoxia cell signaling for cancer therapy. Cancer Metastasis Rev 26 (2007) 341-352
    • (2007) Cancer Metastasis Rev , vol.26 , pp. 341-352
    • Melillo, G.1
  • 117
    • 0036682284 scopus 로고    scopus 로고
    • Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway
    • Rapisarda A., Uranchimeg B., Scudiero D.A., et al. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res 62 (2002) 4316-4324
    • (2002) Cancer Res , vol.62 , pp. 4316-4324
    • Rapisarda, A.1    Uranchimeg, B.2    Scudiero, D.A.3
  • 118
    • 10744231706 scopus 로고    scopus 로고
    • 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
    • Mabjeesh N.J., Escuin D., LaVallee T.M., et al. 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 3 (2003) 363-375
    • (2003) Cancer Cell , vol.3 , pp. 363-375
    • Mabjeesh, N.J.1    Escuin, D.2    LaVallee, T.M.3
  • 119
    • 0036569704 scopus 로고    scopus 로고
    • Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells
    • Mabjeesh N.J., Post D.E., Willard M.T., et al. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res 62 (2002) 2478-2482
    • (2002) Cancer Res , vol.62 , pp. 2478-2482
    • Mabjeesh, N.J.1    Post, D.E.2    Willard, M.T.3
  • 120
    • 33644780111 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha
    • Kong X., Lin Z., Liang D., et al. Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha. Mol Cell Biol 26 (2006) 2019-2028
    • (2006) Mol Cell Biol , vol.26 , pp. 2019-2028
    • Kong, X.1    Lin, Z.2    Liang, D.3
  • 121
    • 0037414180 scopus 로고    scopus 로고
    • YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1
    • Yeo E.J., Chun Y.S., Cho Y.S., et al. YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst 95 (2003) 516-525
    • (2003) J Natl Cancer Inst , vol.95 , pp. 516-525
    • Yeo, E.J.1    Chun, Y.S.2    Cho, Y.S.3
  • 122
    • 4444369682 scopus 로고    scopus 로고
    • Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha
    • Welsh S., Williams R., Kirkpatrick L., et al. Antitumor activity and pharmacodynamic properties of PX-478, an inhibitor of hypoxia-inducible factor-1alpha. Mol Cancer Ther 3 (2004) 233-244
    • (2004) Mol Cancer Ther , vol.3 , pp. 233-244
    • Welsh, S.1    Williams, R.2    Kirkpatrick, L.3
  • 123
    • 0142144338 scopus 로고    scopus 로고
    • The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1α and vascular endothelial growth factor formation
    • Welsh S., Williams R., Birmingham A., et al. The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1α and vascular endothelial growth factor formation. Mol Cancer Ther 2 (2003) 235-243
    • (2003) Mol Cancer Ther , vol.2 , pp. 235-243
    • Welsh, S.1    Williams, R.2    Birmingham, A.3
  • 124
    • 0033231301 scopus 로고    scopus 로고
    • Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes
    • Melillo G., Sausville E.A., Cloud K., et al. Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes. Cancer Res 59 (1999) 5433-5437
    • (1999) Cancer Res , vol.59 , pp. 5433-5437
    • Melillo, G.1    Sausville, E.A.2    Cloud, K.3
  • 125
    • 34547225129 scopus 로고    scopus 로고
    • Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy
    • Cairns R.A., Papandreou I., Sutphin P.D., et al. Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy. Proc Natl Acad Sci U S A 104 (2007) 9445-9450
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 9445-9450
    • Cairns, R.A.1    Papandreou, I.2    Sutphin, P.D.3
  • 126
    • 2342611976 scopus 로고    scopus 로고
    • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules
    • Moeller B.J., Cao Y., Li C.Y., et al. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. Cancer Cell 5 (2004) 429-441
    • (2004) Cancer Cell , vol.5 , pp. 429-441
    • Moeller, B.J.1    Cao, Y.2    Li, C.Y.3
  • 127
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold D.M., Burri P., Beer K.T., et al. Expression of hypoxia-inducible factor-1alpha: a novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res 61 (2001) 2911-2916
    • (2001) Cancer Res , vol.61 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3
  • 128
    • 0036680153 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer
    • Koukourakis M.I., Giatromanolaki A., Sivridis E., et al. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. Int J Radiat Oncol Biol Phys 53 (2002) 1192-1202
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 1192-1202
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3
  • 129
    • 0036569941 scopus 로고    scopus 로고
    • Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients
    • Beasley N.J., Leek R., Alam M., et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res 62 (2002) 2493-2497
    • (2002) Cancer Res , vol.62 , pp. 2493-2497
    • Beasley, N.J.1    Leek, R.2    Alam, M.3
  • 130
    • 0036023422 scopus 로고    scopus 로고
    • Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
    • Hui E.P., Chan A.T., Pezzella F., et al. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res 8 (2002) 2595-2604
    • (2002) Clin Cancer Res , vol.8 , pp. 2595-2604
    • Hui, E.P.1    Chan, A.T.2    Pezzella, F.3
  • 131
    • 0035392959 scopus 로고    scopus 로고
    • Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density
    • Beasley N.J., Wykoff C.C., Watson P.H., et al. Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density. Cancer Res 61 (2001) 5262-5267
    • (2001) Cancer Res , vol.61 , pp. 5262-5267
    • Beasley, N.J.1    Wykoff, C.C.2    Watson, P.H.3
  • 132
    • 0035181306 scopus 로고    scopus 로고
    • Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy
    • Koukourakis M.I., Giatromanolaki A., Sivridis E., et al. Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy. Clin Cancer Res 7 (2001) 3399-3403
    • (2001) Clin Cancer Res , vol.7 , pp. 3399-3403
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3
  • 133
    • 33747176556 scopus 로고    scopus 로고
    • The relation between hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression with anemia and outcome in surgically treated head and neck cancer
    • Winter S.C., Shah K.A., Han C., et al. The relation between hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression with anemia and outcome in surgically treated head and neck cancer. Cancer 107 (2006) 757-766
    • (2006) Cancer , vol.107 , pp. 757-766
    • Winter, S.C.1    Shah, K.A.2    Han, C.3
  • 134
    • 33644849887 scopus 로고    scopus 로고
    • Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial
    • Koukourakis M.I., Bentzen S.M., Giatromanolaki A., et al. Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial. J Clin Oncol 24 (2006) 727-735
    • (2006) J Clin Oncol , vol.24 , pp. 727-735
    • Koukourakis, M.I.1    Bentzen, S.M.2    Giatromanolaki, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.