Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: A prospective study on disease control and preservation of salivary function

Cancer

Volumn 101, Issue 7, 2004, Pages 1584-1593

  Kwong, Dora L W ^a,c   Pow, Edmond H N ^b   Sham, Jonathan S T ^a   McMillan, Anne S ^b   Leung, Lucullus H T ^a   Leung, W Keung ^b   Chua, Daniel T T ^a   Cheng, Ashley C K ^a   Wu, Po M ^a   Au, Gordon K H ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Intensity modulated radiotherapy; Nasopharyngeal carcinoma; Parotid sparing; Salivary flow

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER SURVIVAL; CERVICAL LYMPH NODE; CLINICAL ARTICLE; CLINICAL TRIAL; EARLY CANCER; FEMALE; FOLLOW UP; FUNCTION TEST; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MALE; NASOPHARYNX CARCINOMA; PAROTID GLAND; PH; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE; RADIATION INJURY; RADIATION PROTECTION; SALIVA ANALYSIS; SALIVA BUFFERING CAPACITY; SALIVA PH; SALIVARY GLAND FUNCTION; STIMULATED PAROTID SALIVARY FLOW; STIMULATED WHOLE SALIVARY FLOW; TREATMENT FAILURE; TUMOR VOLUME; XEROSTOMIA;

ADULT; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PAROTID GLAND; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; SURVIVAL RATE;

EID: 4844223514     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20552     Document Type: Article

References (23)

1. Hong Kong Cancer Registry. Cancer incidence and mortality in Hong Kong. Hong Kong: Hong Kong Cancer Registry, Hospital Authority, 2000:38-39.
2. Geara FB, Sanguineti G, Tucker SL, et al. Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of distant metastasis and survival. Radiother Oncol. 1997;43: 53-61.
3. Sanguineti G, Geara F, Garden A, et al. Carcinoma of the nasopharynx treated by radiotherapy alone: determinants of local and regional control. Int J Radiat Oncol Biol Phys. 1997;37:985-996.
4. Ho JHC. Nasopharynx. In: Halnan KE, editor. Treatment of cancer, 1st ed. London: Chapman and Hall, 1982:249-267.
5. Cooper JS, Fu K, Marks J, et al. Late effects of radiation therapy in the head and neck region. Int J Radiat Oncol Biol Phys. 1995;31:1141-1164.
6. Pow EH, McMillan AS, Leung WK, et al. Salivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma. Clin Oral Invest. 2003;7:230-234.
7. Schwarz E, Chiu GK, Leung WK. Oral health status of southern Chinese following head and neck irradiation therapy for nasopharyngeal carcinoma. J Dentistry. 1999;27:21-28.
8. Pow E, McMillan AS, Leung WK, et al. Oral health condition in southern Chinese after radiotherapy for nasopharyngeal carcinoma: extent and nature of the problem. Oral Dis. 2003;9:196-202.
9. Hughes PJ, Scott PM, Kew J, et al. Dysphagia in treated nasopharyngeal cancer. Head Neck. 2000;22:393-397.
10. Wu QW, Mohan R, Morris M, et al. Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas. 1: dosimetric results. Int J Radiat Oncol Biol Phys. 2003;56:573-585.
11. Kam MK, Chau RM, Suen J, et al. Intensity-modulated radiotherapy in nasopharyngeal carcinoma: dosimetric advantage over conventional plans and feasibility of dose escalation. Int J Radiat Oncol Biol Phys. 2003;56:145-157.
12. Eisbruch A, Kim HM, Terrell JE, et al. Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2001;50:695-704.
13. Eisbruch A, Ship JA, Dawson LA, et al. Salivary gland sparing and improved target irradiation by conformal and intensity modulated irradiation of head and neck cancer. World J Surg. 2003;27:832-837.
14. Fleming ID, Cooper JS, Hensen DE, et al., editors. AJCC cancer staging manual, 5th ed. Chapter 4: pharynx (including base of tongue, soft palate, and uvula). Philadelphia: Lippincott-Raven, 1998:33-38.
15. Som PM, Curtin HD, Mancuso AA. An imaging-based classification for the cervical nodes designed as an adjunct to recent clinically based nodal classifications. Arch Otolaryngol Head Neck Surg. 1999;125:388-396.
16. Chao KSC, Ozyigit G, editors. Intensity modulated radiation therapy for head and neck cancer. Chapter 4: dose prescription and target delineation for nodal volume. Philadelphia: Lippincott, 2003:38-49.
17. Webb S. Inverse planning for IMRT: the role of simulated annealing. In: Sternick ES, editor. The theory and practice of intensity modulated radiation therapy. Proceedings of the first NOMOS IMRT workshop, Durango, Colorado. Madison: Advanced Medical Publishing, 1997:51-73.
18. Curran B. Conformal radiation therapy using a multileaf intensity modulating collimator. In: Sternick ES, editor. The theory and practice of intensity modulated radiation therapy. Proceedings of the first NOMOS IMRT workshop, Durango, Colorado. Madison: Advanced Medical Publishing, 1997:75-90.
19. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) [editorial]. Int J Radiat Oncol Biol Phys. 1995;31:1341-1346.
20. Baum BJ. Evaluation of stimulated parotid saliva flow rate in different age groups. J Dent Res. 1981;60:1292-1296.
21. Eisbruch A, Ten-Haken RK, Kim HM, et al. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer. Int J Radiat Oncol Biol Phys. 1999;45:577-587.
22. Lee N, Xia P, Quivey JM, et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: an update of the UCSF experience. Int J Radiat Oncol Biol Phys. 2002;53:12-22.
23. Chao KS, Deasy JO, Markman J, et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys. 2001;49:907-916.