메뉴 건너뛰기




Volumn 32, Issue 7, 2008, Pages 814-826

Cell type dependent endocytic internalization of ErbB2 with an artificial peptide ligand that binds to ErbB2

Author keywords

EC 1; Endocytosis; ErbB2; Internalization; SKBr3; SKOv3

Indexed keywords

CLATHRIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GREEN FLUORESCENT PROTEIN; LIGAND; PEPTIDE;

EID: 44549087930     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2008.03.012     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 9444252957 scopus 로고    scopus 로고
    • Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin
    • Austin C.D., De Maziere A.M., Pisacane P.I., van Dijk S.M., Eigenbrot C., Sliwkowski M.X., et al. Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. Mol Biol Cell 15 (2004) 5268-5282
    • (2004) Mol Biol Cell , vol.15 , pp. 5268-5282
    • Austin, C.D.1    De Maziere, A.M.2    Pisacane, P.I.3    van Dijk, S.M.4    Eigenbrot, C.5    Sliwkowski, M.X.6
  • 2
    • 0035169666 scopus 로고    scopus 로고
    • Mechanism of action of trastuzumab and scientific update
    • Baselga J., Albanell J., Molina M.A., and Arribas J. Mechanism of action of trastuzumab and scientific update. Semin Oncol 28 (2001) 4-11
    • (2001) Semin Oncol , vol.28 , pp. 4-11
    • Baselga, J.1    Albanell, J.2    Molina, M.A.3    Arribas, J.4
  • 3
    • 0029912203 scopus 로고    scopus 로고
    • All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
    • Baulida J., Kraus M.H., Alimandi M., Di Fiore P.P., and Carpenter G. All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J Biol Chem 1 271 (1996) 5251-5257
    • (1996) J Biol Chem , vol.1 , Issue.271 , pp. 5251-5257
    • Baulida, J.1    Kraus, M.H.2    Alimandi, M.3    Di Fiore, P.P.4    Carpenter, G.5
  • 4
    • 0025281906 scopus 로고
    • Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer
    • Berchuck A., Kamel A., Whitaker R., Kerns B., Olt G., Kinney R., et al. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. Cancer Res 50 (1990) 4087-4091
    • (1990) Cancer Res , vol.50 , pp. 4087-4091
    • Berchuck, A.1    Kamel, A.2    Whitaker, R.3    Kerns, B.4    Olt, G.5    Kinney, R.6
  • 6
    • 0037434791 scopus 로고    scopus 로고
    • Structure of the extracellular region of HER2 alone and in complex with the herceptin fab
    • Cho H.S., Mason K., Ramyar K.X., Stanley A.M., Gabelli S.B., Denney D.W., et al. Structure of the extracellular region of HER2 alone and in complex with the herceptin fab. Nature 421 (2003) 756-760
    • (2003) Nature , vol.421 , pp. 756-760
    • Cho, H.S.1    Mason, K.2    Ramyar, K.X.3    Stanley, A.M.4    Gabelli, S.B.5    Denney, D.W.6
  • 7
    • 0037429779 scopus 로고    scopus 로고
    • The deaf and the dumb: the biology of ErbB-2 and ErbB-3
    • Citri A., Skaria K.B., and Yarden Y. The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res 284 (2003) 54-65
    • (2003) Exp Cell Res , vol.284 , pp. 54-65
    • Citri, A.1    Skaria, K.B.2    Yarden, Y.3
  • 8
    • 0035874898 scopus 로고    scopus 로고
    • Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
    • Cuello M., Ettenberg S.A., Clark A.S., Keane M.M., Posner R.H., Nau M.M., et al. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res 61 (2001) 4892-4900
    • (2001) Cancer Res , vol.61 , pp. 4892-4900
    • Cuello, M.1    Ettenberg, S.A.2    Clark, A.S.3    Keane, M.M.4    Posner, R.H.5    Nau, M.M.6
  • 9
    • 0002534401 scopus 로고    scopus 로고
    • Measuring antibody affinity in solution
    • McCafferty J., Hoogenboom R., and Chiswell D.J. (Eds), IRL Press, Oxford
    • Djavadi-Ohaniance L., Goldberg M.E., and Friguet B. Measuring antibody affinity in solution. In: McCafferty J., Hoogenboom R., and Chiswell D.J. (Eds). Antibody engineering: A practical approach (1996), IRL Press, Oxford 77
    • (1996) Antibody engineering: A practical approach , pp. 77
    • Djavadi-Ohaniance, L.1    Goldberg, M.E.2    Friguet, B.3
  • 10
    • 13844306484 scopus 로고    scopus 로고
    • Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy
    • Friedman L.M., Rinon A., Schechter B., Lyass L., Lavi S., Bacus S.S., et al. Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy. Proc Natl Acad Sci USA 102 (2005) 1915-1920
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1915-1920
    • Friedman, L.M.1    Rinon, A.2    Schechter, B.3    Lyass, L.4    Lavi, S.5    Bacus, S.S.6
  • 11
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus Porta D., Beerli R.R., Daly J.M., and Hynes N.E. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16 (1997) 1647-1655
    • (1997) EMBO J , vol.16 , pp. 1647-1655
    • Graus Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 12
    • 28644439423 scopus 로고    scopus 로고
    • The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane
    • Haslekas C., Breen K., Pedersen K.W., Johannessen L.E., Stang E., and Madshus I.H. The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane. Mol Biol Cell 16 (2005) 5832-5842
    • (2005) Mol Biol Cell , vol.16 , pp. 5832-5842
    • Haslekas, C.1    Breen, K.2    Pedersen, K.W.3    Johannessen, L.E.4    Stang, E.5    Madshus, I.H.6
  • 13
    • 0037931402 scopus 로고    scopus 로고
    • Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels
    • Hendriks B.S., Opresko L.K., Wiley H.S., and Lauffenburger D. Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels. J Biol Chem 278 (2003) 23343-23351
    • (2003) J Biol Chem , vol.278 , pp. 23343-23351
    • Hendriks, B.S.1    Opresko, L.K.2    Wiley, H.S.3    Lauffenburger, D.4
  • 14
    • 1642422374 scopus 로고    scopus 로고
    • Association with membrane protrusions makes ErbB2 an internalization-resistant receptor
    • Hommelgaard A.M., Lerdrup M., and van Deurs B. Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol Biol Cell 15 (2004) 1557-1567
    • (2004) Mol Biol Cell , vol.15 , pp. 1557-1567
    • Hommelgaard, A.M.1    Lerdrup, M.2    van Deurs, B.3
  • 15
    • 0035371932 scopus 로고    scopus 로고
    • Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor
    • Houimel M., Schneider P., Terskikh A., and Mach J.P. Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor. Int J Cancer 92 (2001) 748-755
    • (2001) Int J Cancer , vol.92 , pp. 748-755
    • Houimel, M.1    Schneider, P.2    Terskikh, A.3    Mach, J.P.4
  • 16
    • 0024478054 scopus 로고
    • p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
    • Hudziak R.M., Lewis G.D., Winget M., Fendly B.M., Shepard H.M., and Ullrich A. p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol Cell Biol 9 (1989) 1165-1172
    • (1989) Mol Cell Biol , vol.9 , pp. 1165-1172
    • Hudziak, R.M.1    Lewis, G.D.2    Winget, M.3    Fendly, B.M.4    Shepard, H.M.5    Ullrich, A.6
  • 17
    • 0028912598 scopus 로고
    • Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
    • Hurwitz E., Stancovski I., Sela M., and Yarden Y. Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc Natl Acad Sci USA 92 (1995) 3353-3357
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3353-3357
    • Hurwitz, E.1    Stancovski, I.2    Sela, M.3    Yarden, Y.4
  • 18
    • 0035805585 scopus 로고    scopus 로고
    • The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins
    • Jaulin-Bastard F., Saito H., Le B.A., Ollendorff V., Marchetto S., Birnbaum D., et al. The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins. J Biol Chem 276 (2001) 15256-15263
    • (2001) J Biol Chem , vol.276 , pp. 15256-15263
    • Jaulin-Bastard, F.1    Saito, H.2    Le, B.A.3    Ollendorff, V.4    Marchetto, S.5    Birnbaum, D.6
  • 19
    • 0036323958 scopus 로고    scopus 로고
    • Identification and characterization of peptides that bind human ErbB-2 selected from a bacteriophage display library
    • Karasseva N.G., Glinsky V.V., Chen N.X., Komatireddy R., and Quinn T.P. Identification and characterization of peptides that bind human ErbB-2 selected from a bacteriophage display library. J Protein Chem 21 (2002) 287-296
    • (2002) J Protein Chem , vol.21 , pp. 287-296
    • Karasseva, N.G.1    Glinsky, V.V.2    Chen, N.X.3    Komatireddy, R.4    Quinn, T.P.5
  • 20
    • 0034234854 scopus 로고    scopus 로고
    • Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
    • Klapper L.N., Waterman H., Sela M., and Yarden Y. Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res 60 (2000) 3384-3388
    • (2000) Cancer Res , vol.60 , pp. 3384-3388
    • Klapper, L.N.1    Waterman, H.2    Sela, M.3    Yarden, Y.4
  • 21
    • 0032526729 scopus 로고    scopus 로고
    • Differential endocytic routing of homo-and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
    • Lenferink A.E., Pinkas-Kramarski R., van de Poll M.L., van Vugt M.J., Klapper L.N., Tzahar E., et al. Differential endocytic routing of homo-and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers. EMBO J 17 (1998) 3385-3397
    • (1998) EMBO J , vol.17 , pp. 3385-3397
    • Lenferink, A.E.1    Pinkas-Kramarski, R.2    van de Poll, M.L.3    van Vugt, M.J.4    Klapper, L.N.5    Tzahar, E.6
  • 22
    • 31644439697 scopus 로고    scopus 로고
    • Geldanamycin stimulates internalization of EbB2 in a proteasome-dependent way
    • Lerdrup L.N., Hommelgaard M.H., Grandal M., and Van D.B. Geldanamycin stimulates internalization of EbB2 in a proteasome-dependent way. J Cell Sci 119 (2006) 85-95
    • (2006) J Cell Sci , vol.119 , pp. 85-95
    • Lerdrup, L.N.1    Hommelgaard, M.H.2    Grandal, M.3    Van, D.B.4
  • 24
    • 0029879442 scopus 로고    scopus 로고
    • Growth regulation of human breast and ovarian tumor cells by heregulin: evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness
    • Lewis G.D., Lofgren J.A., McMurtrey A.E., Nuijens A., Fendly B.M., Bauer K.D., et al. Growth regulation of human breast and ovarian tumor cells by heregulin: evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness. Cancer Res 56 (1996) 1457-1465
    • (1996) Cancer Res , vol.56 , pp. 1457-1465
    • Lewis, G.D.1    Lofgren, J.A.2    McMurtrey, A.E.3    Nuijens, A.4    Fendly, B.M.5    Bauer, K.D.6
  • 25
    • 0025993767 scopus 로고
    • Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2
    • Maier L.A., Xu F.J., Hester S., Boyer C.M., McKenzie S., Bruskin A.M., et al. Requirements for the internalization of a murine monoclonal antibody directed against the HER-2/neu gene product c-erbB-2. Cancer Res 51 (1991) 5361-5369
    • (1991) Cancer Res , vol.51 , pp. 5361-5369
    • Maier, L.A.1    Xu, F.J.2    Hester, S.3    Boyer, C.M.4    McKenzie, S.5    Bruskin, A.M.6
  • 27
    • 0034854417 scopus 로고    scopus 로고
    • ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
    • Muthuswamy S.K., Li D., Lelievre S., Bissell M.J., and Brugge J.S. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nat Cell Biol 3 (2001) 785-792
    • (2001) Nat Cell Biol , vol.3 , pp. 785-792
    • Muthuswamy, S.K.1    Li, D.2    Lelievre, S.3    Bissell, M.J.4    Brugge, J.S.5
  • 28
    • 44549086602 scopus 로고    scopus 로고
    • Nagaoka T, Fukuda T, Hashizume T, Nishiyama T, Tada H, Yamada H, et al. A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin producing cells with low affinity of binding to ErbB1. J Mol Biol, in press.
    • Nagaoka T, Fukuda T, Hashizume T, Nishiyama T, Tada H, Yamada H, et al. A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin producing cells with low affinity of binding to ErbB1. J Mol Biol, in press.
  • 29
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: receptor heterodimerization in development and cancer
    • Olayioye M.A., Neve R.M., Lane H.A., and Hynes N.E. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 19 (2000) 3159-3167
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3    Hynes, N.E.4
  • 31
    • 4143068213 scopus 로고    scopus 로고
    • Identification of a small peptide that inhibits the phosphorylation of ErbB2 and proliferation of ErbB2 overexpressing breast cancer cells
    • Pero S.C., Shukla G.S., Armstrong A.L., Peterson D., Fuller S.P., Godin K., et al. Identification of a small peptide that inhibits the phosphorylation of ErbB2 and proliferation of ErbB2 overexpressing breast cancer cells. Int J Cancer 111 (2004) 951-960
    • (2004) Int J Cancer , vol.111 , pp. 951-960
    • Pero, S.C.1    Shukla, G.S.2    Armstrong, A.L.3    Peterson, D.4    Fuller, S.P.5    Godin, K.6
  • 32
    • 0031759864 scopus 로고    scopus 로고
    • The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy
    • Ross J.S., and Fletcher J.A. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Stem Cells 16 (1998) 413-428
    • (1998) Stem Cells , vol.16 , pp. 413-428
    • Ross, J.S.1    Fletcher, J.A.2
  • 33
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon D.S., Brandt R., Ciardiello F., and Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19 (1995) 183-232
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 34
    • 0024337144 scopus 로고
    • Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
    • Slamon D.J., Godolphin W., Jones L.A., Holt J.A., Wong S.G., Keith D.E., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244 (1989) 707-712
    • (1989) Science , vol.244 , pp. 707-712
    • Slamon, D.J.1    Godolphin, W.2    Jones, L.A.3    Holt, J.A.4    Wong, S.G.5    Keith, D.E.6
  • 35
    • 0027382449 scopus 로고
    • The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired
    • Sorkin A., Di Fiore P.P., and Carpenter G. The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired. Oncogene 8 (1993) 3021-3028
    • (1993) Oncogene , vol.8 , pp. 3021-3028
    • Sorkin, A.1    Di Fiore, P.P.2    Carpenter, G.3
  • 36
    • 0027620152 scopus 로고
    • Endocytosis of growth factor receptors
    • Sorkin A., and Waters C.M. Endocytosis of growth factor receptors. Bioessays 15 (1993) 375-382
    • (1993) Bioessays , vol.15 , pp. 375-382
    • Sorkin, A.1    Waters, C.M.2
  • 37
    • 0034714283 scopus 로고    scopus 로고
    • Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation
    • Tikhomirov O., and Carpenter G. Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation. J Biol Chem 275 (2000) 26625-26631
    • (2000) J Biol Chem , vol.275 , pp. 26625-26631
    • Tikhomirov, O.1    Carpenter, G.2
  • 38
    • 22144471936 scopus 로고    scopus 로고
    • Identification of cell surface marker candidates on SV-T2 cells using DNA microarray on DLC-coated glass
    • Tuoya, Hirayama K., Nagaoka T., Yu D., Fukuda T., Tada H., et al. Identification of cell surface marker candidates on SV-T2 cells using DNA microarray on DLC-coated glass. Biochem Biophys Res Commun 334 (2005) 263-268
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 263-268
    • Tuoya1    Hirayama, K.2    Nagaoka, T.3    Yu, D.4    Fukuda, T.5    Tada, H.6
  • 39
    • 0029814271 scopus 로고    scopus 로고
    • A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
    • Tzahar E., Waterman H., Chen X., Levkowitz G., Karunagaran D., Lavi S., et al. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 16 (1996) 5276-5287
    • (1996) Mol Cell Biol , vol.16 , pp. 5276-5287
    • Tzahar, E.1    Waterman, H.2    Chen, X.3    Levkowitz, G.4    Karunagaran, D.5    Lavi, S.6
  • 40
    • 0035834461 scopus 로고    scopus 로고
    • Targeted gene transduction of mammalian cells expressing the HER2/neu receptor by filamentous phage
    • Urbanelli L., Ronchini C., Fontana L., Menard S., Orlandi R., and Monaci P. Targeted gene transduction of mammalian cells expressing the HER2/neu receptor by filamentous phage. J Mol Biol 313 (2001) 965-976
    • (2001) J Mol Biol , vol.313 , pp. 965-976
    • Urbanelli, L.1    Ronchini, C.2    Fontana, L.3    Menard, S.4    Orlandi, R.5    Monaci, P.6
  • 41
    • 0032948524 scopus 로고    scopus 로고
    • Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation
    • Wang Z., Zhang L., Yeung T.K., and Chen X. Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol Biol Cell 10 (1999) 1621-1636
    • (1999) Mol Biol Cell , vol.10 , pp. 1621-1636
    • Wang, Z.1    Zhang, L.2    Yeung, T.K.3    Chen, X.4
  • 42
    • 0025155546 scopus 로고
    • Molecular characterization of recombinant human acidic fibroblast growth factor produced in E. coli: comparative studies with human basic fibroblast growth factor
    • Watanabe T., Seno M., Sasada R., and Igarashi K. Molecular characterization of recombinant human acidic fibroblast growth factor produced in E. coli: comparative studies with human basic fibroblast growth factor. Mol Endocrinol 4 (1990) 869-879
    • (1990) Mol Endocrinol , vol.4 , pp. 869-879
    • Watanabe, T.1    Seno, M.2    Sasada, R.3    Igarashi, K.4
  • 43
    • 0034766736 scopus 로고    scopus 로고
    • Biology of HER2 and its importance in breast cancer
    • Yarden Y. Biology of HER2 and its importance in breast cancer. Oncology 61 (2001) 1-13
    • (2001) Oncology , vol.61 , pp. 1-13
    • Yarden, Y.1
  • 45
    • 0024385586 scopus 로고
    • Amplification and rearrangement of c-erb B proto-oncogenes in cancer of human female genital tract
    • Zhang X., Silva E., Gershenson D., and Hung M.C. Amplification and rearrangement of c-erb B proto-oncogenes in cancer of human female genital tract. Oncogene 4 (1989) 985-989
    • (1989) Oncogene , vol.4 , pp. 985-989
    • Zhang, X.1    Silva, E.2    Gershenson, D.3    Hung, M.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.