-
1
-
-
0029053716
-
Cooperative signaling of ErbB-3 and ErbB-2 in neoplastic transformation of human mammary carcinoma cells
-
Alimandi, M., Romano, A., Curia, M.C., Muraro, R., Fedi, P., Aaronson, S.A., Di Fiore, P.P. and Kraus, M.H. (1995) Cooperative signaling of ErbB-3 and ErbB-2 in neoplastic transformation of human mammary carcinoma cells. Oncogene, 15, 1813-1821.
-
(1995)
Oncogene
, vol.15
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
Muraro, R.4
Fedi, P.5
Aaronson, S.A.6
Di Fiore, P.P.7
Kraus, M.H.8
-
2
-
-
0030795612
-
The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
-
Alroy, I. and Yarden, Y. (1997) The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions. FEBS Lett., 410, 83-86.
-
(1997)
FEBS Lett.
, vol.410
, pp. 83-86
-
-
Alroy, I.1
Yarden, Y.2
-
3
-
-
0022485548
-
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
-
Bargmann, C.I., Hung, M.C. and Weinberg, R.A. (1986) Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell, 45, 649-657.
-
(1986)
Cell
, vol.45
, pp. 649-657
-
-
Bargmann, C.I.1
Hung, M.C.2
Weinberg, R.A.3
-
4
-
-
0023624729
-
Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor
-
Barrandon, Y. and Green, H. (1987) Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-α and epidermal growth factor. Cell, 50, 1131-1137.
-
(1987)
Cell
, vol.50
, pp. 1131-1137
-
-
Barrandon, Y.1
Green, H.2
-
5
-
-
0019427474
-
Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts
-
Basu, S.K., Goldstein, J.L., Anderson, R.G.W. and Brown, M.S. (1981) Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts. Cell, 24, 493-502.
-
(1981)
Cell
, vol.24
, pp. 493-502
-
-
Basu, S.K.1
Goldstein, J.L.2
Anderson, R.G.W.3
Brown, M.S.4
-
6
-
-
0029912203
-
All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired
-
Baulida, J., Kraus, M.H., Alimandi, M., Di Fiore, P.P. and Carpenter, G. (1996) All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem., 271, 5251-5257.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5251-5257
-
-
Baulida, J.1
Kraus, M.H.2
Alimandi, M.3
Di Fiore, P.P.4
Carpenter, G.5
-
7
-
-
0029965411
-
Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities
-
Beerli, R.R. and Hynes, N.E. (1996) Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities. J. Biol. Chem., 271, 6071-6076.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6071-6076
-
-
Beerli, R.R.1
Hynes, N.E.2
-
8
-
-
0028229715
-
A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP-kinase pathway
-
Ben-Levy, R., Paterson, H.E. Marshall, C.J. and Yarden, Y. (1994) A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP-kinase pathway. EMBO J., 13, 3302-3311.
-
(1994)
EMBO J.
, vol.13
, pp. 3302-3311
-
-
Ben-Levy, R.1
Paterson, H.E.2
Marshall, C.J.3
Yarden, Y.4
-
9
-
-
0030919509
-
Neuregulins and their receptors: A versatile signaling module in organogenesis and oncogenesis
-
Burden, S. and Yarden, Y. (1997) Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron, 18, 847-855.
-
(1997)
Neuron
, vol.18
, pp. 847-855
-
-
Burden, S.1
Yarden, Y.2
-
10
-
-
0024978029
-
Role of acidic intracellular compartment in the biosynthesis of dictiostelium lysosomal enzymes
-
Cardelli, J.A., Richardson, J. and Meiars, D. (1989) Role of acidic intracellular compartment in the biosynthesis of dictiostelium lysosomal enzymes. J. Biol. Chem., 264, 3454-3464.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 3454-3464
-
-
Cardelli, J.A.1
Richardson, J.2
Meiars, D.3
-
11
-
-
0028176477
-
A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling
-
Carraway, K.L. and Cantley, L.C. (1994) A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling. Cell, 78, 5-8.
-
(1994)
Cell
, vol.78
, pp. 5-8
-
-
Carraway, K.L.1
Cantley, L.C.2
-
12
-
-
0029884288
-
Insulin regulates heregulin binding and ErbB3 expression in rat hepatocytes
-
Carver, R.S., Sliwkowski, M.X., Sitaric, S. and Russell, W.E. (1996) Insulin regulates heregulin binding and ErbB3 expression in rat hepatocytes. J. Biol. Chem., 271, 13491-13496.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13491-13496
-
-
Carver, R.S.1
Sliwkowski, M.X.2
Sitaric, S.3
Russell, W.E.4
-
13
-
-
0029804204
-
The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH-3T3 cells
-
Cohen, B.D., Kiener, P.K., Green, J.M., Foy, L., Fell, H.P. and Zhang, K. (1996) The relationship between human epidermal growth-like factor receptor expression and cellular transformation in NIH-3T3 cells. J. Biol. Chem., 271, 30897-30903.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30897-30903
-
-
Cohen, B.D.1
Kiener, P.K.2
Green, J.M.3
Foy, L.4
Fell, H.P.5
Zhang, K.6
-
14
-
-
0023196582
-
ErbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells
-
Di Fiore, P.P., Pierce, J.H., Kraus, M.H., Segatto, O., King, C.R. and Aaronson, S.A. (1987) erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science, 237, 178-182.
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Kraus, M.H.3
Segatto, O.4
King, C.R.5
Aaronson, S.A.6
-
15
-
-
0027422247
-
The pathway to signal achievement
-
Eagan, S.E. and Weinberg, R.A. (1993) The pathway to signal achievement. Nature, 365, 781-783.
-
(1993)
Nature
, vol.365
, pp. 781-783
-
-
Eagan, S.E.1
Weinberg, R.A.2
-
16
-
-
14844349947
-
Epidermal growth factor and transforming growth factor-α: Differential intracellular routing and processing of ligand-receptor complexes
-
Ebner, R. and Derynck, R. (1991) Epidermal growth factor and transforming growth factor-α: differential intracellular routing and processing of ligand-receptor complexes. Cell Regul., 2, 599-612.
-
(1991)
Cell Regul.
, vol.2
, pp. 599-612
-
-
Ebner, R.1
Derynck, R.2
-
17
-
-
0025359062
-
Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body
-
Felder, S., Miller, K., Moehren, G., Ullrich, A., Schlessinger, J. and Hopkins, C.R. (1990) Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body. Cell, 61, 623-634.
-
(1990)
Cell
, vol.61
, pp. 623-634
-
-
Felder, S.1
Miller, K.2
Moehren, G.3
Ullrich, A.4
Schlessinger, J.5
Hopkins, C.R.6
-
18
-
-
0024230493
-
Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes
-
Gladhaug, I.P. and Christofferson, T. (1988) Rapid constitutive internalization and externalization of epidermal growth factor receptors in isolated rat hepatocytes. J. Biol. Chem., 263, 12199-12203.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 12199-12203
-
-
Gladhaug, I.P.1
Christofferson, T.2
-
19
-
-
0023840804
-
Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies
-
Glenney, J.R., Chen, W.S., Lazar, C.S., Walton, G.M., Zokas, L.M., Rosenfeld, M.G. and Gill, G.N. (1988) Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies. Cell, 52, 675-684.
-
(1988)
Cell
, vol.52
, pp. 675-684
-
-
Glenney, J.R.1
Chen, W.S.2
Lazar, C.S.3
Walton, G.M.4
Zokas, L.M.5
Rosenfeld, M.G.6
Gill, G.N.7
-
20
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta, D., Beerly, R., Daly, J.M. and Hynes, N.E. (1997) ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J., 16, 1647-1655.
-
(1997)
EMBO J.
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerly, R.2
Daly, J.M.3
Hynes, N.E.4
-
21
-
-
0020538097
-
Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines
-
Greenberger, J.S., Sakakeeny, M.A., Humphries, R.K., Eaves, C.J. and Eckner, R.J. (1983) Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines. Proc. Natl Acad. Sci. USA, 80, 2931-2935.
-
(1983)
Proc. Natl Acad. Sci. USA
, vol.80
, pp. 2931-2935
-
-
Greenberger, J.S.1
Sakakeeny, M.A.2
Humphries, R.K.3
Eaves, C.J.4
Eckner, R.J.5
-
22
-
-
0030783917
-
Reduced ability of transforming growth factor-α to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2
-
Gulliford, T.J., Huang, G.C., Ouyang, X. and Epstein, E.J. (1997) Reduced ability of transforming growth factor-α to induce EGF receptor heterodimerization and downregulation suggests a mechanism of oncogenic synergy with ErbB2. Oncogene, 15, 2219-2223.
-
(1997)
Oncogene
, vol.15
, pp. 2219-2223
-
-
Gulliford, T.J.1
Huang, G.C.2
Ouyang, X.3
Epstein, E.J.4
-
23
-
-
0029914718
-
Epidermal growth factor behaves as a partial agonist in hepatocytes: Effects on DNA synthesis in primary culture and competition with transforming growth factor α
-
Guren, T.K., Thoresen, G.H., Dajani, O.F., Taraldsrud, E., Moberg, E.R. and Christoffersen, T. (1996) Epidermal growth factor behaves as a partial agonist in hepatocytes: effects on DNA synthesis in primary culture and competition with transforming growth factor α. Growth Factors, 13, 171-179.
-
(1996)
Growth Factors
, vol.13
, pp. 171-179
-
-
Guren, T.K.1
Thoresen, G.H.2
Dajani, O.F.3
Taraldsrud, E.4
Moberg, E.R.5
Christoffersen, T.6
-
24
-
-
0028168569
-
Insect cell-expressed p180ErbB3 possesses an impaired tyrosine kinase activity
-
Guy, P.M. Platko, J.V., Cantley, L.C. Cerione, R.A. and Carraway, K.L. (1994) Insect cell-expressed p180ErbB3 possesses an impaired tyrosine kinase activity. Proc. Natl Acad. Sci. USA, 91, 8132-8136.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 8132-8136
-
-
Guy, P.M.1
Platko, J.V.2
Cantley, L.C.3
Cerione, R.A.4
Carraway, K.L.5
-
25
-
-
0031557112
-
Intraendosomal degradation of transforming growth factor α
-
Hamel, F.G., Siford, G.L., Jones, J. and Duckworth, W.C. (1997) Intraendosomal degradation of transforming growth factor α. Mol. Cell. Endocrinol., 126, 185-192.
-
(1997)
Mol. Cell. Endocrinol.
, vol.126
, pp. 185-192
-
-
Hamel, F.G.1
Siford, G.L.2
Jones, J.3
Duckworth, W.C.4
-
26
-
-
0024094325
-
Biological activities of EGF receptor mutants with individually altered autophosphorylation sites
-
Honegger, A.M., Dull, T.J., Bellot, F., Van Obbergghen, E., Szapary, D., Schmidt, A., Ullrich, A. and Schlessinger, J. (1988) Biological activities of EGF receptor mutants with individually altered autophosphorylation sites. EMBO J., 7, 3045-3052.
-
(1988)
EMBO J.
, vol.7
, pp. 3045-3052
-
-
Honegger, A.M.1
Dull, T.J.2
Bellot, F.3
Van Obbergghen, E.4
Szapary, D.5
Schmidt, A.6
Ullrich, A.7
Schlessinger, J.8
-
27
-
-
0023430930
-
Increased expression of the putative growth factor receptor p185HER-2 causes transformation and tumorigenesis of NIH-3T3
-
Hudziak, R.M. Schlessinger, J. and Ullrich, A. (1987) Increased expression of the putative growth factor receptor p185HER-2 causes transformation and tumorigenesis of NIH-3T3. Proc. Natl Acad. Sci. USA, 84, 7159-7163.
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 7159-7163
-
-
Hudziak, R.M.1
Schlessinger, J.2
Ullrich, A.3
-
28
-
-
0028670125
-
The biology of erbB-2/neu/HER-2 and its role in cancer
-
Hynes, N.E. and Stern, D.F. (1994) The biology of erbB-2/neu/HER-2 and its role in cancer. Biochem. Biophys. Acta, 1198, 165-184.
-
(1994)
Biochem. Biophys. Acta
, vol.1198
, pp. 165-184
-
-
Hynes, N.E.1
Stern, D.F.2
-
29
-
-
0023872192
-
Establishment of mouse cell lines that constitutively secrete large quantities of interleukins 2, 3, 4 or 5, using modified cDNA expression vectors
-
Karasuyama, H. and Melchers, F. (1988) Establishment of mouse cell lines that constitutively secrete large quantities of interleukins 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol., 18, 97-104.
-
(1988)
Eur. J. Immunol.
, vol.18
, pp. 97-104
-
-
Karasuyama, H.1
Melchers, F.2
-
30
-
-
0030030072
-
ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer
-
Karunagaran, D., Tzahar, E., Beerli, R.R., Chen, X., Graus-Porta, D., Ratzkin, B.J., Seger, R., Hynes, N.E. and Yarden, Y. (1996) ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. EMBO J., 15, 254-264.
-
(1996)
EMBO J.
, vol.15
, pp. 254-264
-
-
Karunagaran, D.1
Tzahar, E.2
Beerli, R.R.3
Chen, X.4
Graus-Porta, D.5
Ratzkin, B.J.6
Seger, R.7
Hynes, N.E.8
Yarden, Y.9
-
31
-
-
0028077047
-
Epidermal growth factor-dependent association of phosphatidylinositol 3′-kinase with the erbB-3 gene product
-
Kim, H.-H., Sierke, S.L. and Koland, J.G. (1994) Epidermal growth factor-dependent association of phosphatidylinositol 3′-kinase with the erbB-3 gene product. J. Biol. Chem., 269, 24747-24755.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24747-24755
-
-
Kim, H.-H.1
Sierke, S.L.2
Koland, J.G.3
-
32
-
-
0030959114
-
A subclass of tumor-inhibitory monoclonal antibodies to erbB-2/HER2 blocks crosstalk with growth factor receptors
-
Klapper, L.N., Vaisman, N., Hurwitz, E., Pinkas-Kramarski, R., Yarden, Y. and Sela, M. (1997) A subclass of tumor-inhibitory monoclonal antibodies to erbB-2/HER2 blocks crosstalk with growth factor receptors. Oncogene, 14, 2099-2109.
-
(1997)
Oncogene
, vol.14
, pp. 2099-2109
-
-
Klapper, L.N.1
Vaisman, N.2
Hurwitz, E.3
Pinkas-Kramarski, R.4
Yarden, Y.5
Sela, M.6
-
33
-
-
0025765803
-
SH-2 and SH-3 domains: Elements that control interactions of cytoplasmic signaling proteins
-
Koch, A.C. Anderson, D., Moran, M.F., Ellis, C. and Pawson, T. (1991) SH-2 and SH-3 domains: Elements that control interactions of cytoplasmic signaling proteins. Science, 252, 668-674.
-
(1991)
Science
, vol.252
, pp. 668-674
-
-
Koch, A.C.1
Anderson, D.2
Moran, M.F.3
Ellis, C.4
Pawson, T.5
-
34
-
-
0024395587
-
Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts
-
Kokai, Y. Myers, J.N., Wada, T., Brown, V.I., LeVea, C.M., Davis, J.G., Dobashi, K. and Greene, M.I. (1989) Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts. Cell 58, 287-292.
-
(1989)
Cell
, vol.58
, pp. 287-292
-
-
Kokai, Y.1
Myers, J.N.2
Wada, T.3
Brown, V.I.4
LeVea, C.M.5
Davis, J.G.6
Dobashi, K.7
Greene, M.I.8
-
35
-
-
0024435665
-
Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor α
-
Korc, M. and Finman, J.E. (1989) Attenuated processing of epidermal growth factor in the face of marked degradation of transforming growth factor α. J. Biol. Chem., 264, 14990-14999.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 14990-14999
-
-
Korc, M.1
Finman, J.E.2
-
36
-
-
0031081140
-
Vulval development in Caenorhabditis elegans
-
Kornfeld, K. (1997) Vulval development in Caenorhabditis elegans. Trends Genet., 13, 55-61.
-
(1997)
Trends Genet.
, vol.13
, pp. 55-61
-
-
Kornfeld, K.1
-
37
-
-
0028245026
-
Identification of the high affinity binding site of transforming growth factor-α (TGF-α) for the chicken epidermal growth factor (EGF) receptor using EGF/TGF-α chimeras
-
Kramer, R.H., Leferink, A.E.G., van Buern-Koornneef, I.L., van der Meer, A., van de Poll, M.L.M. and van Zoelen, E.J.J. (1994) Identification of the high affinity binding site of transforming growth factor-α (TGF-α) for the chicken epidermal growth factor (EGF) receptor using EGF/TGF-α chimeras. J. Biol. Chem., 269, 8708-8711.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8708-8711
-
-
Kramer, R.H.1
Leferink, A.E.G.2
Van Buern-Koornneef, I.L.3
Van Der Meer, A.4
Van De Poll, M.L.M.5
Van Zoelen, E.J.J.6
-
38
-
-
0028884413
-
Requirement for neuregulin receptor erbB2 in neural and cardiac development
-
Lee, K.F., Simon, H., Chen, H., Bates, B., Hung, M.C. and Hauser, C. (1995) Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature, 378, 394-398.
-
(1995)
Nature
, vol.378
, pp. 394-398
-
-
Lee, K.F.1
Simon, H.2
Chen, H.3
Bates, B.4
Hung, M.C.5
Hauser, C.6
-
39
-
-
0030663020
-
Superagonistic behaviour of epidermal growth factor/transforming growth factor-α chimeras: Correlation with receptor routing after ligand-induced internalization
-
Lenferink, A.E.G., Kramer, R.H., van Vugt, M.J.H., Konigswieser, M., di-Fiore, P.P., van Zoelen, E.J.J. and van de Poll, L.M.L. (1997) Superagonistic behaviour of epidermal growth factor/transforming growth factor-α chimeras: correlation with receptor routing after ligand-induced internalization. Biochem. J., 327, 859-865.
-
(1997)
Biochem. J.
, vol.327
, pp. 859-865
-
-
Lenferink, A.E.G.1
Kramer, R.H.2
Van Vugt, M.J.H.3
Konigswieser, M.4
Di-Fiore, P.P.5
Van Zoelen, E.J.J.6
Van De Poll, L.M.L.7
-
40
-
-
0029917264
-
Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins
-
Levkowitz, G., Klapper, L.N., Tzahar, E., Freywald, A., Sela, M. and Yarden, Y. (1996) Coupling of the c-Cbl protooncogene product to ErbB-1/EGF-receptor but not to other ErbB proteins. Oncogene, 12, 1117-1125.
-
(1996)
Oncogene
, vol.12
, pp. 1117-1125
-
-
Levkowitz, G.1
Klapper, L.N.2
Tzahar, E.3
Freywald, A.4
Sela, M.5
Yarden, Y.6
-
41
-
-
0029740245
-
A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor α and epidermal growth factor in cultured fetal rat hepatocytes
-
Lipeski, L.E., Boylan, J.M. and Gruppuso, P.A. (1996) A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor α and epidermal growth factor in cultured fetal rat hepatocytes. Biochem. Mol. Biol. Int., 39, 975-983.
-
(1996)
Biochem. Mol. Biol. Int.
, vol.39
, pp. 975-983
-
-
Lipeski, L.E.1
Boylan, J.M.2
Gruppuso, P.A.3
-
42
-
-
0025687686
-
The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand
-
Lonardo, F., Di Marco, E., King, C.R., Pierce, J.H., Segatto, O., Aaronson, S.A. and Di Fiore, P.P. (1990) The normal erbB-2 product is an atypical receptor-like tyrosine kinase with constitutive activity in the absence of ligand. New Biol., 2, 992-1003.
-
(1990)
New Biol.
, vol.2
, pp. 992-1003
-
-
Lonardo, F.1
Di Marco, E.2
King, C.R.3
Pierce, J.H.4
Segatto, O.5
Aaronson, S.A.6
Di Fiore, P.P.7
-
43
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C.J. (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell, 80, 179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
44
-
-
0021399556
-
Biosynthesis of the epidermal growth factor receptor in A431 cels
-
Mayes, E.L.V. and Waterfield, M.D. (1984) Biosynthesis of the epidermal growth factor receptor in A431 cels. EMBO J., 3, 531-537.
-
(1984)
EMBO J.
, vol.3
, pp. 531-537
-
-
Mayes, E.L.V.1
Waterfield, M.D.2
-
45
-
-
0028168073
-
Activation of the p70/p85 S6-kinase by a pathway independent of p21ras
-
Ming, X.-F., Buegering, B.M.T., Wensrom, S., Cleasson-Welsh, L., Heldin, C.-H., Bos, J.L., Kozma, S.C. and Thomas, G. (1994) Activation of the p70/p85 S6-kinase by a pathway independent of p21ras. Nature, 371, 426-429.
-
(1994)
Nature
, vol.371
, pp. 426-429
-
-
Ming, X.-F.1
Buegering, B.M.T.2
Wensrom, S.3
Cleasson-Welsh, L.4
Heldin, C.-H.5
Bos, J.L.6
Kozma, S.C.7
Thomas, G.8
-
46
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosman, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65, 55-63.
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosman, T.1
-
47
-
-
0025362617
-
Fusions of Staphylococal protein A
-
Nilson, B. and Abrahmsen, L. (1990) Fusions of Staphylococal protein A. Methods Enymol., 185, 144-161.
-
(1990)
Methods Enymol.
, vol.185
, pp. 144-161
-
-
Nilson, B.1
Abrahmsen, L.2
-
48
-
-
0027465159
-
Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships
-
Peles, E., Ben-Levy, R., Tzahar, E., Liu, N., Wen, D. and Yarden, Y. (1993) Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships. EMBO J., 12, 961-971.
-
(1993)
EMBO J.
, vol.12
, pp. 961-971
-
-
Peles, E.1
Ben-Levy, R.2
Tzahar, E.3
Liu, N.4
Wen, D.5
Yarden, Y.6
-
49
-
-
2142843806
-
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions
-
Pinkas-Kramarski, R., Soussan, L., Waterman, H., Levkowitz, G., Alroy, I., Klapper, L., Lavi, S., Seger, R., Ratzkin, B., Sela, M. and Yarden, Y. (1996a) Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J., 15, 2452-2467.
-
(1996)
EMBO J.
, vol.15
, pp. 2452-2467
-
-
Pinkas-Kramarski, R.1
Soussan, L.2
Waterman, H.3
Levkowitz, G.4
Alroy, I.5
Klapper, L.6
Lavi, S.7
Seger, R.8
Ratzkin, B.9
Sela, M.10
Yarden, Y.11
-
50
-
-
0029783549
-
Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations
-
Pinkas-Kramarski, R., Shelly, M., Glathe, S., Ratzkin, B.J. and Yarden, Y. (1996b) Neu differentiation factor/neuregulin isoforms activate distinct receptor combinations. J. Biol. Chem., 271, 19029-19032.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19029-19032
-
-
Pinkas-Kramarski, R.1
Shelly, M.2
Glathe, S.3
Ratzkin, B.J.4
Yarden, Y.5
-
51
-
-
0029850715
-
The interaction of an epidermal growth factor/transforming growth factor α tail chimera with the human epidermal growth factor receptor reveals unexpected complexities
-
Puddicombe, S.M., Wood, L., Chamberlin, S.G. and Davies, D. (1996) The interaction of an epidermal growth factor/transforming growth factor α tail chimera with the human epidermal growth factor receptor reveals unexpected complexities. J. Biol. Chem., 271, 30392-30397.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30392-30397
-
-
Puddicombe, S.M.1
Wood, L.2
Chamberlin, S.G.3
Davies, D.4
-
52
-
-
0029852598
-
Engineering epidermal growth factor for enhanced mitogenic potency
-
Reddy, C.C., Niyogi, S.K., Wells, A., Wiley, H.S. and Lauffenburger, D.A. (1996a) Engineering epidermal growth factor for enhanced mitogenic potency. Nature Biotech., 14, 1696-1699.
-
(1996)
Nature Biotech.
, vol.14
, pp. 1696-1699
-
-
Reddy, C.C.1
Niyogi, S.K.2
Wells, A.3
Wiley, H.S.4
Lauffenburger, D.A.5
-
53
-
-
0029976245
-
Receptor-mediated effects of ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor α
-
Reddy, C.C., Wells, A. and Laffenburger, D.A. (1996b) Receptor-mediated effects of ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor α. J. Cell. Physiol., 166, 512-522.
-
(1996)
J. Cell. Physiol.
, vol.166
, pp. 512-522
-
-
Reddy, C.C.1
Wells, A.2
Laffenburger, D.A.3
-
54
-
-
0025797051
-
Sequential processing of epidermal growth factor in early and late endosomes of rat liver
-
Renfrew, C.A. and Hubbard, A.L. (1991) Sequential processing of epidermal growth factor in early and late endosomes of rat liver. J. Biol. Chem., 266, 4348-4356.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 4348-4356
-
-
Renfrew, C.A.1
Hubbard, A.L.2
-
55
-
-
0029118223
-
The cellular response to neuregulins is governed by complex interactions of the ErbB receptor family
-
Riese, D.J., van Raaij, T.M. Plowman, G.D., Andrews, G.C. and Stern, D.F. (1995) The cellular response to neuregulins is governed by complex interactions of the ErbB receptor family. Mol. Cell Biol., 15, 5770-5776.
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 5770-5776
-
-
Riese, D.J.1
Van Raaij, T.M.2
Plowman, G.D.3
Andrews, G.C.4
Stern, D.F.5
-
56
-
-
0029829040
-
The epidermal growth factor receptor couples transforming growth factor-α, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4
-
Riese, D.J., Kim, E.D., Elenius, K., Buckley, S., Klagsbrun, M., Plowman, G.D. and Stern, D.F. (1996) The epidermal growth factor receptor couples transforming growth factor-α, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4. J. Biol. Chem., 271, 20047-20052.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20047-20052
-
-
Riese, D.J.1
Kim, E.D.2
Elenius, K.3
Buckley, S.4
Klagsbrun, M.5
Plowman, G.D.6
Stern, D.F.7
-
57
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon, D.S., Brandt, R., Ciardiello, F. and Normanno, N. (1995) Epidermal growth factor-related peptides and their receptors in human malignancies. Crit. Rev. Oncol. Hematol., 19, 183-232.
-
(1995)
Crit. Rev. Oncol. Hematol.
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
58
-
-
0022501030
-
Transforming growth factor α: More potent angiogenic mediator than epidermal growth factor
-
Schreiber, A.B., Winkler, M.E. and Derynck, R. (1986) Transforming growth factor α: more potent angiogenic mediator than epidermal growth factor. Science, 232, 1250-1253.
-
(1986)
Science
, vol.232
, pp. 1250-1253
-
-
Schreiber, A.B.1
Winkler, M.E.2
Derynck, R.3
-
59
-
-
0029011218
-
The MAP kinase signaling cascade
-
Seger, R. and Krebs, E.G. (1995) The MAP kinase signaling cascade. FASEB J., 9, 726-735.
-
(1995)
FASEB J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
60
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon, D.J., Clark, G.M., Wong, S.G., Levin, W.J., Ullrich, A. and McGuire, W.L. (1987) Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science, 235, 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
61
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon, D.J., Godolphin, W., Jones, L.A., Holt, J.A., Wong, S.G., Keith, D.E., Levin, W.J., Stuart, S.G., Udove, J., Ullrich, A. and Press, M.F. (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science, 244, 707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.F.11
-
62
-
-
0028302018
-
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor
-
Soltoff, S.P., Carraway, K.L., Prigent, S.A., Gullick, W.G. and Cantley, L.C. (1994) ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factor. Mol. Cell Biol., 14, 3550-3558.
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 3550-3558
-
-
Soltoff, S.P.1
Carraway, K.L.2
Prigent, S.A.3
Gullick, W.G.4
Cantley, L.C.5
-
63
-
-
0027620152
-
Endocytosis of growth factor receptors
-
Sorkin, A. and Waters, C.M. (1993) Endocytosis of growth factor receptors. BioEssays, 15, 375-382.
-
(1993)
BioEssays
, vol.15
, pp. 375-382
-
-
Sorkin, A.1
Waters, C.M.2
-
64
-
-
0027382449
-
The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimera is internalization impaired
-
Sorkin, A., Di Fiore, P.P. and Carpenter, G. (1993) The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimera is internalization impaired. Oncogene, 8, 3021-3028.
-
(1993)
Oncogene
, vol.8
, pp. 3021-3028
-
-
Sorkin, A.1
Di Fiore, P.P.2
Carpenter, G.3
-
65
-
-
0028248951
-
Molecular and clinical aspects of the Neu/ErbB-2 receptor tyrosine kinase
-
Stancovski, I., Sela, M. and Yarden, Y. (1994) Molecular and clinical aspects of the Neu/ErbB-2 receptor tyrosine kinase. Cancer Treat. Res., 71, 161-191.
-
(1994)
Cancer Treat. Res.
, vol.71
, pp. 161-191
-
-
Stancovski, I.1
Sela, M.2
Yarden, Y.3
-
66
-
-
0024673026
-
Characterization of degP, a gene required for proteolysis in the cell envelope and for growth of Escherichia coli at high temperature
-
Strauch, K.L., Johnson, K. and Beckwith, J. (1989) Characterization of degP, a gene required for proteolysis in the cell envelope and for growth of Escherichia coli at high temperature. J. Bacteriol., 171, 2689-2696.
-
(1989)
J. Bacteriol.
, vol.171
, pp. 2689-2696
-
-
Strauch, K.L.1
Johnson, K.2
Beckwith, J.3
-
67
-
-
0032549036
-
The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: From orphanhood to multiple stromal ligands
-
Tzahar, E. and Yarden, Y. (1998) The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands. BBA Rev. Cancer, 1377, M25-M37.
-
(1998)
BBA Rev. Cancer
, vol.1377
-
-
Tzahar, E.1
Yarden, Y.2
-
68
-
-
0027971393
-
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms
-
Tzahar, E., Levkowitz, G., Karunagaran, D., Yi, L., Peles, E., Lavi, S., Chang, D., Liu, N., Yayon, A., Wen, D. and Yarden, Y. (1994) ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms. J. Biol. Chem., 269, 25226-25233.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25226-25233
-
-
Tzahar, E.1
Levkowitz, G.2
Karunagaran, D.3
Yi, L.4
Peles, E.5
Lavi, S.6
Chang, D.7
Liu, N.8
Yayon, A.9
Wen, D.10
Yarden, Y.11
-
69
-
-
0029814271
-
A hierarchical network of inter-receptor interactions determines signal transduction by NDF/neuregulin and EGF
-
Tzahar, E., Waterman, H., Chen, X., Levkowitz, G., Karunagaran, D., Lavi, S., Ratzkin, B.J. and Yarden, Y. (1996) A hierarchical network of inter-receptor interactions determines signal transduction by NDF/neuregulin and EGF. Mol. Cell Biol., 16, 5276-5287.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
Levkowitz, G.4
Karunagaran, D.5
Lavi, S.6
Ratzkin, B.J.7
Yarden, Y.8
-
70
-
-
20244367576
-
Bivalency of EGF-like ligands drives the ErbB signaling network
-
Tzahar, E., Pinkas-Kramarski, R., Moyer, J., Klapper, L.N., Alroy, I., Levkowitz, G., Shelly, M., Henis, S., Eisenstein, M., Ratzkin, B.J., Sela, M., Andrews, G.C. and Yarden, Y. (1997) Bivalency of EGF-like ligands drives the ErbB signaling network. EMBO J., 16, 4938-1950.
-
(1997)
EMBO J.
, vol.16
, pp. 4938-11950
-
-
Tzahar, E.1
Pinkas-Kramarski, R.2
Moyer, J.3
Klapper, L.N.4
Alroy, I.5
Levkowitz, G.6
Shelly, M.7
Henis, S.8
Eisenstein, M.9
Ratzkin, B.J.10
Sela, M.11
Andrews, G.C.12
Yarden, Y.13
-
71
-
-
0029114837
-
A single amino acid exchange. Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with hjgh affinity for the chicken EGF receptor
-
van de Poll, M.L.M., Lenferink, A.E.G., van Vugt, M.J.H., Jacobs, J.J.L., Janssen, J.W.H., Joldersma, M. and van Zoelen, E.J.J. (1995) A single amino acid exchange. Arg-45 to Ala, generates an epidermal growth factor (EGF) mutant with hjgh affinity for the chicken EGF receptor. J. Biol. Chem., 270, 22337-22343.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22337-22343
-
-
Van De Poll, M.L.M.1
Lenferink, A.E.G.2
Van Vugt, M.J.H.3
Jacobs, J.J.L.4
Janssen, J.W.H.5
Joldersma, M.6
Van Zoelen, E.J.J.7
-
72
-
-
0028170817
-
Receptor protein-tyrosine kinases and their signal transduction pathways
-
van der Geer, P., Hunter, T. and Lindberg, R.A. (1994) Receptor protein-tyrosine kinases and their signal transduction pathways. Ann. Rev. Cell Biol., 10, 251-337.
-
(1994)
Ann. Rev. Cell Biol.
, vol.10
, pp. 251-337
-
-
Van Der Geer, P.1
Hunter, T.2
Lindberg, R.A.3
-
73
-
-
0022967006
-
Transforming growth factor-β and retinoic aid modulate phenotypic transformation of normal rat kidney cells by epidermal growth factor and platelet-derived growth factor
-
van Zoelen, E.J.J., van Oostwaard, T.M.J. and de Laat, S.W. (1986) Transforming growth factor-β and retinoic aid modulate phenotypic transformation of normal rat kidney cells by epidermal growth factor and platelet-derived growth factor. J. Biol. Chem., 261, 5003-5009.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5003-5009
-
-
Van Zoelen, E.J.J.1
Van Oostwaard, T.M.J.2
De Laat, S.W.3
-
74
-
-
0027157829
-
An exact analysis of ligand displacement and saturation curves
-
van Zoelen, E.J.J., Kramer, R.H., van Reen, M.M.M., Veerkamp, J.A. and Ross, H.A. (1993) An exact analysis of ligand displacement and saturation curves. Biochemistry, 32, 6275-6280.
-
(1993)
Biochemistry
, vol.32
, pp. 6275-6280
-
-
Van Zoelen, E.J.J.1
Kramer, R.H.2
Van Reen, M.M.M.3
Veerkamp, J.A.4
Ross, H.A.5
-
75
-
-
0025647921
-
Resistance to receptor-mediated degradation of a murine epidermal growth factor analogue (EGF-Val-47) potentiates its mitogenic activity
-
Walker, F., Nice, E., Fabri, L., Moy, F.J., Liu, J.-F., Wu, R., Scheraga, H.A. and Burgess, A.W. (1990) Resistance to receptor-mediated degradation of a murine epidermal growth factor analogue (EGF-Val-47) potentiates its mitogenic activity. Biochemistry, 29, 10635-10640.
-
(1990)
Biochemistry
, vol.29
, pp. 10635-10640
-
-
Walker, F.1
Nice, E.2
Fabri, L.3
Moy, F.J.4
Liu, J.-F.5
Wu, R.6
Scheraga, H.A.7
Burgess, A.W.8
-
76
-
-
0029162564
-
Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3
-
Wallasch, C. Weiss, F.U., Niederfellner, G., Jallal, B., Issing, W. and Ullrich, A. (1995) Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. EMBO J., 14, 4267-4275.
-
(1995)
EMBO J.
, vol.14
, pp. 4267-4275
-
-
Wallasch, C.1
Weiss, F.U.2
Niederfellner, G.3
Jallal, B.4
Issing, W.5
Ullrich, A.6
-
77
-
-
0032577487
-
Alternative intracellular routing of ErbB receptors may determine signaling potency
-
Waterman, H., Sabanai, I., Geiger, B. and Yarden, Y. (1998) Alternative intracellular routing of ErbB receptors may determine signaling potency. J. Biol. Chem., 273, 13819-13827.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13819-13827
-
-
Waterman, H.1
Sabanai, I.2
Geiger, B.3
Yarden, Y.4
-
78
-
-
0024505028
-
A point mutation in the neu oncogene mimics ligand induction of receptor aggregation
-
Weiner, D.B., Liu, J., Cohen, J.A., Williams, W.V. and Greene, M.I. (1989) A point mutation in the neu oncogene mimics ligand induction of receptor aggregation. Nature, 339, 230-231.
-
(1989)
Nature
, vol.339
, pp. 230-231
-
-
Weiner, D.B.1
Liu, J.2
Cohen, J.A.3
Williams, W.V.4
Greene, M.I.5
-
79
-
-
0025139326
-
Ligand-induced transformation by a non-internalizing epidermal growth factor receptor
-
Wells, A., Welsh, J.B., Lazar, C.S., Wiley, H.S., Gill, G.N. and Rosenfeld, M.G. (1990) Ligand-induced transformation by a non-internalizing epidermal growth factor receptor. Science, 247, 962-964.
-
(1990)
Science
, vol.247
, pp. 962-964
-
-
Wells, A.1
Welsh, J.B.2
Lazar, C.S.3
Wiley, H.S.4
Gill, G.N.5
Rosenfeld, M.G.6
-
80
-
-
0030968648
-
Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB-2/neu
-
Worthylake, R. and Wiley, H.S. (1997) Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB-2/neu. J. Biol. Chem., 272, 8594-8601.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8594-8601
-
-
Worthylake, R.1
Wiley, H.S.2
-
81
-
-
0030064531
-
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2
-
Zhang, K., Sun, J., Liu, N., Wen, D., Chang, D., Thomason, A. and Yoshinaga, S.K. (1996) Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J. Biol. Chem., 271, 3884-3890.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3884-3890
-
-
Zhang, K.1
Sun, J.2
Liu, N.3
Wen, D.4
Chang, D.5
Thomason, A.6
Yoshinaga, S.K.7
|