Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: Implications for cancer immunotherapy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 6, 2005, Pages 1915-1920

  Friedman, Lilach M ^a   Rinon, Ariel ^a   Schechter, Bilha ^a   Lyass, Ljuba ^b   Lavi, Sara ^a   Bacus, Sarah S ^b   Sela, Michael ^a   Yarden, Yosef ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b Targeted Molecular Diagnostics   (United States)

Author keywords

Antibody; ErbB; Growth factor; Oncogene; Signal transduction

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITOPE; MONOCLONAL ANTIBODY; PROTEIN TYROSINE KINASE; TRASTUZUMAB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER IMMUNOTHERAPY; CELL SURFACE; CONTROLLED STUDY; DEGRADATION; DOWN REGULATION; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; DOWN-REGULATION; DYNAMINS; ENDOCYTOSIS; EPITOPES; FEMALE; GENES, REPORTER; HUMANS; IMMUNOTHERAPY; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 13844306484     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409610102     Document Type: Article

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