The inhibitory effect of ErbB2 on epidermal growth factor-induced formation of clathrin-coated pits correlates with retention of epidermal growth factor receptor-ErbB2 oligomeric complexes at the plasma membrane

Molecular Biology of the Cell

Volumn 16, Issue 12, 2005, Pages 5832-5842

  Haslekås, Camilla ^a   Breen, Kamilla ^a   Pedersen, Ketil W ^a   Johannessen, Lene E ^a   Stang, Espen ^a   Madshus, Inger Helene ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CLATHRIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBIN; OLIGOMER; PDZ PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; GENETIC TRANSFECTION; INTERNALIZATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UBIQUITINATION;

ANIMALS; AORTA; CELL MEMBRANE; CLATHRIN-COATED VESICLES; ENDOTHELIUM, VASCULAR; EPIDERMAL GROWTH FACTOR; HUMANS; MICROSCOPY, CONFOCAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; SWINE;

ANIMALIA;

EID: 28644439423     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E05-05-0456     Document Type: Article

References (42)

1. Austin, C. D., De Maziere, A. M., Pisacane, P. I., van Dijk, S. M., Eigenbrot, C., Sliwkowski, M. X., Klumperman, J., and Scheller, R. H. (2004). Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. Mol. Biol. Cell 15, 5268-5282.
2. Babst, M., Odorizzi, G., Estepa, E. J., and Emr, S. D. (2000). Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic 1, 248-258.
3. Baulida, J., Kraus, M. H., Alimandi, M., Di Fiore, P. P., and Carpenter, G. (1996). All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired. J. Biol. Chem. 271, 5251-5257.
4. Benmerah, A., Bayrou, M., Cerf-Bensussan, N., and Dautry-Varsat, A. (1999). Inhibition of clathrin-coated pit assembly by an Eps15 mutant. J. Cell Scei. 112, 1303-1311.
5. Birrane, G., Chung, J., and Ladias, J. A. (2003). Novel mode of ligand recognition by the Erbin PDZ domain. J. Biol. Chem. 278, 1399-1402.
6. Borg, J. P., Marchetto, S., Le Bivic, A., Ollendorff, V., Jaulin-Bastard, F., Saito, H., Fournier, E., Adelaide, J., Margolis, B., and Birnbaum, D. (2000). ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor. Nat. Cell Biol. 2, 407-414.
7. Brandt, B. H., et al. (1999). c-erbB-2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells. FASEB J. 13, 1939-1949.
8. Chazin, V. R., Kaleko, M., Miller, A. D., and Slamon, D. J. (1992). Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor. Oncogene 7, 1859-1866.
9. Di Fiore, P. P., Pierce, J. H., Kraus, M. H., Segatto, O., King, C. R., and Aaronson, S. A. (1987). erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science 237, 178-182.
10. Garrett, T. P., et al. (2003). The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. Mol. Cell 11, 495-505.
11. Garrett, T. P., et al. (2002). Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 110, 763-773.
12. Griffiths, G. (1993). Fine Structure Immunocytochemistry, Berlin: Springer-Verlag.
13. Griffiths, G., McDowall, A., Back, R., and Dubochet, J. (1984). On the preparation of cryosections for immunocytochemistry. J. Ultrastruct. Res. 89, 65-78.
14. Griffiths, G., Simons, K., Warren, G., and Tokuyasu, K. T. (1983). Immunoelectron microscopy using thin, frozen sections: application to studies of the intracellular transport of Semliki Forest virus spike glycoproteins. Methods Enzymol. 96, 466-485.
15. Hendriks, B. S., Wiley, H. S., and Lauffenburger, D. (2003). HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanisms. Biophys. J. 85, 2732-2745.
16. Hommelgaard, A. M., Lerdrup, M., and van Deurs, B. (2004). Association with membrane protrusions makes ErbB2 an internalization-resistant receptor. Mol. Biol. Cell 15, 1557-1567.
17. Huang, F., Khvorova, A., Marshall, W., and Sorkin, A. (2004). Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J. Biol. Chem. 279, 16657-16661.
18. Ignatoski, K. M., Lapointe, A. J., Radany, E. H., and Ethier, S. P. (1999). erbB-2 overexpression in human mammary epithelial cells confers growth factor independence. Endocrinology 140, 3615-3622.
19. Jaulin-Bastard, F., Saito, H., Le Bivic, A., Ollendorff, V., Marchetto, S., Birnbaum, D., and Borg, J. P. (2001). The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins. J. Biol. Chem. 276, 15256-15263.
20. Jiang, X., Huang, F., Marusyk, A., and Sorkin, A. (2003). Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol. Biol. Cell 14, 858-870.
21. Johansen, F. E., Braathen, R., and Brandtzaeg, P. (2001). The J chain is essential for polymeric immunoglobulin receptor-mediated epithelial transport of IgA. J. Immunol. 167, 5185-5192.
22. Klapper, L. N., Kirschbaum, M. H., Sela, M., and Yarden, Y. (2000). Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv. Cancer Res. 77, 25-79.
23. Lenferink, A. E., Pinkas-Kramarski, R., van de Poll, M. L., van Vugt, M. J., Klapper, L. N., Tzahar, E., Waterman, H., Sela, M., van Zoelen, E. J., and Yarden, Y. (1998). Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers. EMBO J. 17, 3385-3397.
24. Longva, K. E., Pedersen, N. M., Haslekas, C., Stang, E., and Madshus, I. H. (2005). Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int. J. Cancer 116, 359-367.
25. Lund, K. A., Opresko, L. K., Starbuck, C., Walsh, B. J., and Wiley, H. S. (1990). Quantitative analysis of the endocytic system involved in hormone-induced receptor internalization. J. Biol. Chem. 265, 15713-15723.
26. Ogiso, H., et al. (2002). Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 110, 775-787.
27. Pinkas-Kramarski, R., et al. (1996). Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions. EMBO J. 15, 2452-2467.
28. Schlessinger, J. (2002). Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110, 669-672.
29. Shelly, M., Mosesson, Y., Citri, A., Lavi, S., Zwang, Y., Melamed-Book, N., Aroeti, B., and Yarden, Y. (2003). Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7. Dev. Cell 5, 475-486.
30. Skarpen, E., et al. (1998). Endocytosed epidermal growth factor (EGF) receptors contribute to the EGF-mediated growth arrest in A431 cells by inducing a sustained increase in p21/CIP1. Exp. Cell Res. 243, 161-172.
31. Slamon, D. J., Clark, G. M., Wong, S. G., Levin, W. J., Ullrich, A., and McCuire, W. L. (1987). Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235, 177-182.
32. Sliwkowski, M. X., Schaefer, G., Akita, R. W., Lofgren, J. A., Fitzpatrick, V. D., Nuijens, A., Fendly, B. M., Cerione, R. A., Vandlen, R. L., and Carraway, K. L., 3rd. (1994). Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin. J. Biol. Chem. 269, 14661-14665.
33. Sorkin, A., Di Fiore, P. P., and Carpenter, G. (1993). The carboxyl terminus of epidermal growth factor receptor/erbB-2 chimerae is internalization impaired. Oncogene 8, 3021-3028.
34. Sorkin, A., and Von Zastrow, M. (2002). Signal transduction and endocytosis: close encounters of many kinds. Nat. Rev. Mol. Cell. Biol. 3, 600-614.
35. Spencer, K. S., Graus-Porta, D., Leng, J., Hynes, N. E., and Klemke, R. L. (2000). ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases. J. Cell Biol. 148, 385-397.
36. Wallasch, C., Weiss, F. U., Niederfellner, G., Jallal, B., Issing, W., and Ullrich, A. (1995). Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3. EMBO J. 14, 4267-4275.
37. Wang, Z., Zhang, L., Yeung, T. K., and Chen, X. (1999). Endocytosis deficiency of epidermal growth factor (EGF) receptor-ErbB2 heterodimers in response to EGF stimulation. Mol. Biol. Cell 10, 1621-1636.
38. Waterman, H., and Yarden, Y. (2001), Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases. FEBS Lett. 490, 142-152.
39. Wiley, H. S., Woolf, M. F., Opresko, L. K., Burke, P. M., Will, B., Morgan, J. R., and Lauffenburger, D. A. (1998). Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization. J. Cell Biol. 143, 1317-1328.
40. Worthylake, R., Opresko, L. K., and Wiley, H. S. (1999). ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J. Biol. Chem. 274, 8865-8874.
41. Yarden, Y. (2001). Biology of HER2 and its importance in breast cancer. Oncology 61 (suppl 2), 1-13.
42. Yarden, Y., and Sliwkowski, M. X. (2001). Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2, 127-137.