-
1
-
-
0035473994
-
Childhood acute lymphoblastic leukaemia - Current status and future perspectives
-
Pui CH, Campana D, Evans WE. Childhood acute lymphoblastic leukaemia - current status and future perspectives. Lancet Oncol. 2001;2:597-607.
-
(2001)
Lancet Oncol
, vol.2
, pp. 597-607
-
-
Pui, C.H.1
Campana, D.2
Evans, W.E.3
-
2
-
-
0036675211
-
What is the optimal therapy for childhood AML?
-
Loeb DM, Arceci RJ. What is the optimal therapy for childhood AML? Oncology. 2002;16:1057-1066.
-
(2002)
Oncology
, vol.16
, pp. 1057-1066
-
-
Loeb, D.M.1
Arceci, R.J.2
-
3
-
-
0036015001
-
Progress and controversies in the treatment of pediatric acute myelogenous leukemia
-
Arceci RJ. Progress and controversies in the treatment of pediatric acute myelogenous leukemia. Curr Opin Hematol. 2002;9:353-360.
-
(2002)
Curr Opin Hematol
, vol.9
, pp. 353-360
-
-
Arceci, R.J.1
-
4
-
-
1542269168
-
FLT3 Inhibitors: A paradigm for the development of targeted therapies for pediatric cancer
-
Brown P, Small D. FLT3 Inhibitors: a paradigm for the development of targeted therapies for pediatric cancer. Eur J Cancer. 2004;40:707-721.
-
(2004)
Eur J Cancer
, vol.40
, pp. 707-721
-
-
Brown, P.1
Small, D.2
-
5
-
-
0346258290
-
Novel FLT3 tyrosine kinase inhibitors
-
Levis M, Small D. Novel FLT3 tyrosine kinase inhibitors. Expert Opin Investig Drugs. 2003;12:1951-1962.
-
(2003)
Expert Opin Investig Drugs
, vol.12
, pp. 1951-1962
-
-
Levis, M.1
Small, D.2
-
6
-
-
0141836914
-
FLT3: ITDoes matter in leukemia
-
Levis M, Small D. FLT3: ITDoes matter in leukemia. Leukemia. 2003;17:1738-1752.
-
(2003)
Leukemia
, vol.17
, pp. 1738-1752
-
-
Levis, M.1
Small, D.2
-
7
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood. 2002;100:1532-1542.
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
8
-
-
0141465061
-
The role of FLT3 in haematopoietic malignancies
-
Stirewalt DL, Radich JP. The role of FLT3 in haematopoietic malignancies. Nat Rev Cancer. 2003;3:650-665.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 650-665
-
-
Stirewalt, D.L.1
Radich, J.P.2
-
9
-
-
13344282746
-
Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias
-
Carow CE, Levenstein M, Kaufmann SH, et al. Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias. Blood. 1996;87:1089-1096.
-
(1996)
Blood
, vol.87
, pp. 1089-1096
-
-
Carow, C.E.1
Levenstein, M.2
Kaufmann, S.H.3
-
10
-
-
9244260192
-
Human FLT3/FLK2 receptor tyrosine kinase is expressed at the surface of normal and malignant hematopoietic cells
-
Rosnet O, Buhring HJ, Marchetto S, et al. Human FLT3/FLK2 receptor tyrosine kinase is expressed at the surface of normal and malignant hematopoietic cells. Leukemia. 1996;10:238-248.
-
(1996)
Leukemia
, vol.10
, pp. 238-248
-
-
Rosnet, O.1
Buhring, H.J.2
Marchetto, S.3
-
11
-
-
0026457216
-
Expression of the FMS/KIT-like gene FLT3 in human acute leukemias of the myeloid and lymphoid lineages
-
Birg F, Courcoul M, Rosnet O, et al. Expression of the FMS/KIT-like gene FLT3 in human acute leukemias of the myeloid and lymphoid lineages. Blood. 1992;80:2584-2593.
-
(1992)
Blood
, vol.80
, pp. 2584-2593
-
-
Birg, F.1
Courcoul, M.2
Rosnet, O.3
-
12
-
-
9144269029
-
FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells
-
Zheng R, Levis M, Piloto O, et al. FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells. Blood. 2004;103:267-274.
-
(2004)
Blood
, vol.103
, pp. 267-274
-
-
Zheng, R.1
Levis, M.2
Piloto, O.3
-
13
-
-
0030002950
-
Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells
-
Drexler HG. Expression of FLT3 receptor and response to FLT3 ligand by leukemic cells. Leukemia. 1996;10:588-599.
-
(1996)
Leukemia
, vol.10
, pp. 588-599
-
-
Drexler, H.G.1
-
14
-
-
0029145627
-
Expression of FLT3 receptor and FLT3-ligand in human leukemia-lymphoma cell lines
-
Meierhoff G, Dehmel U, Gruss HJ, et al. Expression of FLT3 receptor and FLT3-ligand in human leukemia-lymphoma cell lines. Leukemia. 1995;9:1368-1372.
-
(1995)
Leukemia
, vol.9
, pp. 1368-1372
-
-
Meierhoff, G.1
Dehmel, U.2
Gruss, H.J.3
-
15
-
-
0029100754
-
Expression of the flt3 receptor and its ligand on hematopoietic cells
-
Brasel K, Escobar S, Anderberg R, de Vries P, Gruss HJ, Lyman SD. Expression of the flt3 receptor and its ligand on hematopoietic cells. Leukemia. 1995;9:1212-1218.
-
(1995)
Leukemia
, vol.9
, pp. 1212-1218
-
-
Brasel, K.1
Escobar, S.2
Anderberg, R.3
De Vries, P.4
Gruss, H.J.5
Lyman, S.D.6
-
16
-
-
0038712179
-
Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: A functional characterization of Flt3-ligand effects in AML cell populations with and without genetic Flt3 abnormalities
-
Bruserud O, Hovland R, Wergeland L, Huang TS, Gjertsen BT. Flt3-mediated signaling in human acute myelogenous leukemia (AML) blasts: a functional characterization of Flt3-ligand effects in AML cell populations with and without genetic Flt3 abnormalities. Haematologica. 2003;88:416-428.
-
(2003)
Haematologica
, vol.88
, pp. 416-428
-
-
Bruserud, O.1
Hovland, R.2
Wergeland, L.3
Huang, T.S.4
Gjertsen, B.T.5
-
17
-
-
0030451722
-
Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
-
Nakao M, Yokota S, Iwai T, et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia. 1996;10:1911-1918.
-
(1996)
Leukemia
, vol.10
, pp. 1911-1918
-
-
Nakao, M.1
Yokota, S.2
Iwai, T.3
-
18
-
-
0035871889
-
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
-
Yamamoto Y, Kiyoi H, Nakano Y, et al. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood. 2001;97:2434-2439.
-
(2001)
Blood
, vol.97
, pp. 2434-2439
-
-
Yamamoto, Y.1
Kiyoi, H.2
Nakano, Y.3
-
19
-
-
0034936404
-
Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia
-
Abu-Duhier FM, Goodeve AC, Wilson GA, Care RS, Peake IR, Reilly JT. Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia. Br J Haematol. 2001;113:983-988.
-
(2001)
Br J Haematol
, vol.113
, pp. 983-988
-
-
Abu-Duhier, F.M.1
Goodeve, A.C.2
Wilson, G.A.3
Care, R.S.4
Peake, I.R.5
Reilly, J.T.6
-
20
-
-
0031883328
-
FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates
-
Lavagna-Sevenier C, Marchetto S, Birnbaum D, Rosnet O. FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates. Leukemia. 1998;12:301-310.
-
(1998)
Leukemia
, vol.12
, pp. 301-310
-
-
Lavagna-Sevenier, C.1
Marchetto, S.2
Birnbaum, D.3
Rosnet, O.4
-
21
-
-
0034649210
-
Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase
-
Zhang S, Broxmeyer HE. Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase. Biochem Biophys Res Commun. 2000;277:195-199.
-
(2000)
Biochem Biophys Res Commun
, vol.277
, pp. 195-199
-
-
Zhang, S.1
Broxmeyer, H.E.2
-
22
-
-
0033020705
-
Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells
-
Zhang S, Mantel C, Broxmeyer HE. Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells. J Leukoc Biol. 1999;65:372-380.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 372-380
-
-
Zhang, S.1
Mantel, C.2
Broxmeyer, H.E.3
-
23
-
-
0033582304
-
p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells
-
Zhang S, Broxmeyer HE. p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2, SHIP, and a tyrosine-phosphorylated 100-kDa protein in Flt3 ligand-stimulated hematopoietic cells. Biochem Biophys Res Commun. 1999;254:440-445.
-
(1999)
Biochem Biophys Res Commun
, vol.254
, pp. 440-445
-
-
Zhang, S.1
Broxmeyer, H.E.2
-
24
-
-
9044233643
-
Expression and signal transduction of the FLT3 tyrosine kinase receptor
-
Rosnet O, Buhring HJ, deLapeyriere O, et al. Expression and signal transduction of the FLT3 tyrosine kinase receptor. Acta Haematol. 1996;95:218-223.
-
(1996)
Acta Haematol
, vol.95
, pp. 218-223
-
-
Rosnet, O.1
Buhring, H.J.2
DeLapeyriere, O.3
-
25
-
-
0034605042
-
Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling
-
Zhang S, Fukuda S, Lee Y, et al. Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling. J Exp Med. 2000;192:719-728.
-
(2000)
J Exp Med
, vol.192
, pp. 719-728
-
-
Zhang, S.1
Fukuda, S.2
Lee, Y.3
-
26
-
-
0031686409
-
Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
-
Kiyoi H, Towatari M, Yokota S, et al. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia. 1998;12:1333-1337.
-
(1998)
Leukemia
, vol.12
, pp. 1333-1337
-
-
Kiyoi, H.1
Towatari, M.2
Yokota, S.3
-
27
-
-
0037061747
-
Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain
-
Kiyoi H, Ohno R, Ueda R, Saito H, Naoe T. Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain. Oncogene. 2002;21:2555-2563.
-
(2002)
Oncogene
, vol.21
, pp. 2555-2563
-
-
Kiyoi, H.1
Ohno, R.2
Ueda, R.3
Saito, H.4
Naoe, T.5
-
28
-
-
0035168677
-
Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia
-
Meshinchi S, Woods WG, Stirewalt DL, et al. Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia. Blood. 2001;97:89-94.
-
(2001)
Blood
, vol.97
, pp. 89-94
-
-
Meshinchi, S.1
Woods, W.G.2
Stirewalt, D.L.3
-
29
-
-
0037219507
-
FLT3 internal tandem duplication in childhood acute myeloid leukaemia: Association with hyperleucocytosis in acute promyelocytic leukaemia
-
Arrigoni P, Beretta C, Silvestri D, et al. FLT3 internal tandem duplication in childhood acute myeloid leukaemia: association with hyperleucocytosis in acute promyelocytic leukaemia. Br J Haematol. 2003;120:89-92.
-
(2003)
Br J Haematol
, vol.120
, pp. 89-92
-
-
Arrigoni, P.1
Beretta, C.2
Silvestri, D.3
-
30
-
-
0037096857
-
Clinical relevance of internal tandem duplication of the FLT3 gene in childhood acute myeloid leukemia
-
Liang DC, Shih LY, Hung IJ, et al. Clinical relevance of internal tandem duplication of the FLT3 gene in childhood acute myeloid leukemia. Cancer. 2002;94:3292-3298.
-
(2002)
Cancer
, vol.94
, pp. 3292-3298
-
-
Liang, D.C.1
Shih, L.Y.2
Hung, I.J.3
-
31
-
-
0001097136
-
Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children
-
Xu F, Taki T, Yang HW, et al. Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children. Br J Haematol. 1999;105:155-162.
-
(1999)
Br J Haematol
, vol.105
, pp. 155-162
-
-
Xu, F.1
Taki, T.2
Yang, H.W.3
-
32
-
-
0032757551
-
Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia
-
Kondo M, Horibe K, Takahashi Y, et al. Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia. Med Pediatr Oncol. 1999;33:525-529.
-
(1999)
Med Pediatr Oncol
, vol.33
, pp. 525-529
-
-
Kondo, M.1
Horibe, K.2
Takahashi, Y.3
-
33
-
-
0032931560
-
Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia
-
The Children's Cancer and Leukemia Study Group, Japan
-
Iwai T, Yokota S, Nakao M, et al. Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan. Leukemia. 1999;13:38-43.
-
(1999)
Leukemia
, vol.13
, pp. 38-43
-
-
Iwai, T.1
Yokota, S.2
Nakao, M.3
-
34
-
-
0141482006
-
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: Prognostic significance and relation to cellular drug resistance
-
Zwaan CM, Meshinchi S, Radich JP, et al. FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance. Blood. 2003;102:2387-2394.
-
(2003)
Blood
, vol.102
, pp. 2387-2394
-
-
Zwaan, C.M.1
Meshinchi, S.2
Radich, J.P.3
-
35
-
-
0041737454
-
Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia
-
Meshinchi S, Stirewalt DL, Alonzo TA, et al. Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia. Blood. 2003;102:1474-1479.
-
(2003)
Blood
, vol.102
, pp. 1474-1479
-
-
Meshinchi, S.1
Stirewalt, D.L.2
Alonzo, T.A.3
-
36
-
-
0035437140
-
A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations
-
Levis M, Tse KF, Smith BD, Garrett E, Small D. A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations. Blood. 2001;98:885-887.
-
(2001)
Blood
, vol.98
, pp. 885-887
-
-
Levis, M.1
Tse, K.F.2
Smith, B.D.3
Garrett, E.4
Small, D.5
-
37
-
-
0036624916
-
A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo
-
Levis M, Allebach J, Tse KF, et al. A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo. Blood. 2002;99:3885-3891.
-
(2002)
Blood
, vol.99
, pp. 3885-3891
-
-
Levis, M.1
Allebach, J.2
Tse, K.F.3
-
38
-
-
0036595143
-
Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412
-
Weisberg E, Boulton C, Kelly LM, et al. Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. Cancer Cell. 2002;1:433-443.
-
(2002)
Cancer Cell
, vol.1
, pp. 433-443
-
-
Weisberg, E.1
Boulton, C.2
Kelly, L.M.3
-
39
-
-
0037441745
-
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3
-
Spiekermann K, Dirschinger RJ, Schwab R, et al. The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3. Blood. 2003;101:1494-1504.
-
(2003)
Blood
, vol.101
, pp. 1494-1504
-
-
Spiekermann, K.1
Dirschinger, R.J.2
Schwab, R.3
-
40
-
-
0037108298
-
SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase
-
Yee KW, O'Farrell AM, Smolich BD, et al. SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase. Blood. 2002;100:2941-2949.
-
(2002)
Blood
, vol.100
, pp. 2941-2949
-
-
Yee, K.W.1
O'Farrell, A.M.2
Smolich, B.D.3
-
41
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
O'Farrell AM, Abrams TJ, Yuen HA, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood. 2003;101:3597-3605.
-
(2003)
Blood
, vol.101
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
-
42
-
-
0013102301
-
CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)
-
Kelly LM, Yu JC, Boulton CL, et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML). Cancer Cell. 2002;1:421-432.
-
(2002)
Cancer Cell
, vol.1
, pp. 421-432
-
-
Kelly, L.M.1
Yu, J.C.2
Boulton, C.L.3
-
43
-
-
1842420032
-
Single agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
-
Smith BD, Levis M, Beran M, et al. Single agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood. 2004;103:3669-3676.
-
(2004)
Blood
, vol.103
, pp. 3669-3676
-
-
Smith, B.D.1
Levis, M.2
Beran, M.3
-
44
-
-
1842463109
-
A randomized phase II trial of the tyrosine kinase inhibitor PKC412 in patients with acute myeloid leukemia (AML)/high-risk myelodysplastic syndromes (MDS) characterized by wild-type (WT) or mutated FLT3
-
Estey E, Fisher T, Giles F, et al. A randomized phase II trial of the tyrosine kinase inhibitor PKC412 in patients with acute myeloid leukemia (AML)/high-risk myelodysplastic syndromes (MDS) characterized by wild-type (WT) or mutated FLT3 [abstract]. Blood. 2003;102:2270a.
-
(2003)
Blood
, vol.102
-
-
Estey, E.1
Fisher, T.2
Giles, F.3
-
45
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
46
-
-
0000957062
-
Asymptotically efficient rank in variant test procedures
-
Peto R, Peto J. Asymptotically efficient rank in variant test procedures. J R Stat Soc A. 1972;135:185-206.
-
(1972)
J R Stat Soc A
, vol.135
, pp. 185-206
-
-
Peto, R.1
Peto, J.2
-
47
-
-
0031884911
-
Feasibility, toxicity, and biologic response of interleukin-2 after consolidation chemotherapy for acute myelogenous leukemia: A report from the Children's Cancer Group
-
Sievers EL, Lange BJ, Sondel PM, et al. Feasibility, toxicity, and biologic response of interleukin-2 after consolidation chemotherapy for acute myelogenous leukemia: a report from the Children's Cancer Group. J Clin Oncol. 1998;16:914-919.
-
(1998)
J Clin Oncol
, vol.16
, pp. 914-919
-
-
Sievers, E.L.1
Lange, B.J.2
Sondel, P.M.3
-
48
-
-
4444245178
-
Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941
-
Lange BJ, Dinndorf P, Smith FO, et al. Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941. J Clin Oncol. 2004;22:150-156.
-
(2004)
J Clin Oncol
, vol.22
, pp. 150-156
-
-
Lange, B.J.1
Dinndorf, P.2
Smith, F.O.3
-
49
-
-
4444369400
-
FLT3 internal tandem duplication is a prognostic factor for poor outcome in pediatric AML; a CCG-1961 study
-
Meshinchi S, Alonzo TA, Gerbing R, Lange B, Radich JP. FLT3 internal tandem duplication is a prognostic factor for poor outcome in pediatric AML; a CCG-1961 study [abstract]. Blood. 2003;102:335a.
-
(2003)
Blood
, vol.102
-
-
Meshinchi, S.1
Alonzo, T.A.2
Gerbing, R.3
Lange, B.4
Radich, J.P.5
-
50
-
-
0035476264
-
Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: A cancer and leukemia group B study
-
Whitman SP, Archer KJ, Feng L, et al. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study. Cancer Res. 2001;61:7233-7239.
-
(2001)
Cancer Res
, vol.61
, pp. 7233-7239
-
-
Whitman, S.P.1
Archer, K.J.2
Feng, L.3
-
51
-
-
0035885955
-
The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: Analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
-
Kottaridis PD, Gale RE, Frew ME, et al. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood. 2001;98:1752-1759.
-
(2001)
Blood
, vol.98
, pp. 1752-1759
-
-
Kottaridis, P.D.1
Gale, R.E.2
Frew, M.E.3
-
52
-
-
0037097716
-
Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: Association with FAB subtypes and identification of subgroups with poor prognosis
-
Thiede C, Steudel C, Mohr B, et al. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood. 2002;99:4326-4335.
-
(2002)
Blood
, vol.99
, pp. 4326-4335
-
-
Thiede, C.1
Steudel, C.2
Mohr, B.3
-
53
-
-
0023019005
-
Use of MTT colorimetric assay to measure cell activation
-
Gerlier D, Thomasset N. Use of MTT colorimetric assay to measure cell activation. J Immunol Methods. 1986;94:57-63.
-
(1986)
J Immunol Methods
, vol.94
, pp. 57-63
-
-
Gerlier, D.1
Thomasset, N.2
-
54
-
-
0030054904
-
Flt3-ligand production by human bone marrow stromal cells
-
Lisovsky M, Braun SE, Ge Y, et al. Flt3-ligand production by human bone marrow stromal cells. Leukemia. 1996;10:1012-1018.
-
(1996)
Leukemia
, vol.10
, pp. 1012-1018
-
-
Lisovsky, M.1
Braun, S.E.2
Ge, Y.3
-
55
-
-
0034598830
-
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines
-
Hayakawa F, Towatari M, Kiyoi H, et al. Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. Oncogene. 2000;19:624-631.
-
(2000)
Oncogene
, vol.19
, pp. 624-631
-
-
Hayakawa, F.1
Towatari, M.2
Kiyoi, H.3
|