The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 36, 2004, Pages 13312-13317

  Helbling, Daniel ^a   Mueller, Beatrice U ^a   Timchenko, Nikolai A ^b   Hagemeijer, Anne ^c   Jotterand, Martine ^d   Meyer Monard, Sandrine ^e   Lister, Andrew ^f   Rowley, Janet D ^g   Huegli, Barbara ^a   Fey, Martin F ^a   Pabst, Thomas ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e UNIVERSITY HOSPITAL BASEL   (Switzerland)

^f ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^g UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AML1 MDS1 EVI1 FUSION PROTEIN; CALRETICULIN; GENE PRODUCT; HYBRID PROTEIN; MESSENGER RNA; PROTEIN CEBPA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; AME GENE; ARTICLE; BINDING AFFINITY; BLAST CELL; BLAST CELL CRISIS; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DNA BINDING; FUSION GENE; GENE ACTIVATION; GENE FUNCTION; GENE REPRESSION; GENETIC CODE; GRANULOPOIESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN TARGETING;

ADULT; AGED; CALRETICULIN; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CORE BINDING FACTOR ALPHA 2 SUBUNIT; FEMALE; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MALE; MIDDLE AGED; ONCOGENE PROTEINS, FUSION; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TRANSLOCATION, GENETIC; U937 CELLS;

EID: 4444254797     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404731101     Document Type: Article

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