Transcription factor C/EBPα: Novel sites of expression and cloning of the human gene

Biological Chemistry

Volumn 378, Issue 5, 1997, Pages 373-379

  Swart, Guido W M ^a   Van Groningen, Jan J M ^a   Van Ruissen, Fred ^b   Bergers, Mieke ^b   Schalkwijk, Joost ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Aorta; C EBP ; Epidermis; Human transcription factor; Keratinocytes

Indexed keywords

BINDING PROTEIN; LEUCINE ZIPPER PROTEIN; RECOMBINANT PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; AORTA; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL DIFFERENTIATION; COLON; CONTROLLED STUDY; EPIDERMIS CELL; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INTRON; KERATINOCYTE; KIDNEY CELL; LIVER CELL; LUNG; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT; SEQUENCE HOMOLOGY; SKIN BIOPSY; SKIN CELL; SMOOTH MUSCLE FIBER; TISSUE DISTRIBUTION; TRANSACTIVATION;

ANIMALIA;

EID: 0030906954     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/bchm.1997.378.5.373     Document Type: Article

References (32)

1. Akira, S., Isshiki, H., Sugita, T., Tanabe, O., Kinoshita, S., Nishio, Y., Nakajima, T., Hirano, T., and Kishimoto, T. (1990). A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J. 9, 1897-1906.
2. Alkemade, J.A.C., Molhuizen, H.O.F., Ponec, M., Kempenaar, J.A., Zeeuwen, P.L.J.M., de Jongh, G.J., van Vlijmen-Willems, I.M.J.J., van Erp, P.E.J., van de Kerkhof, P.C.M., and Schalkwijk, J. (1994). SKALP/Elafin is an inducible proteinase inhibitor in human epidermal keratinocytes. J. Cell Sci. 107, 2335-2342.
3. Antonson, P., and Xanthopoulos, K.G. (1995). Molecular cloning, sequence and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha). Biochem. Biophys. Res. Commun. 215, 106-113.
4. Auffray, C., and Rougeon, F. (1980). Purification of mouse immunoglobulin heavy chain mRNAs from total myeloma tumor RNA. Eur. J. Biochem. 107, 303-314.
5. Birkenmeier, E.H., Gwynn, B., Howard, S., Jerry, J., Gordon, J.I., Landschulz, W.H., and McKnight, S.L. (1989). Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes Dev. 3, 1146-1156.
6. Calkhoven, C.F., AB, G., and Wijnholds, J. (1992). cC/EBP, a chicken transcription factor of the leucine-zipper C/EBP family. Nucl. Acids Res. 20, 4093.
7. Calkhoven, C.F., Bouwman, P.R.J., Snippe, L., and AB, G. (1994). Translation start site multiplicity of the CCAAT/enhancer binding protein alpha mRNA is dictated by a small 5′ open reading frame. Nucl. Acids Res. 22, 5540-5547.
8. Cao, Z., Umek, R.M., and McKnight, S.L. (1991). Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5, 1538-1552.
9. Chen, Y., Hu, H., and Atkinson, B.G. (1994). Characterization and expression of C/EBP-like genes in the liver of Rana Catesbeiana tadpoles during spontaneous and thyroid hormone-induced metamorphosis. Dev. Genet. 15, 366-377.
10. Darlington, G.J., Wang, N., and Hanson, R.W. (1995). C/EBP alpha: a critical regulator of genes governing integrative metabolic processes. Curr. Opin. Genet. Dev. 5, 565-570.
11. Descombes, P., and Schibler, U. (1991). A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell 67, 569-579.
12. Devereux, J., Haeberli, P., and Smithies, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids. Res. 12, 387-395.
13. Feinberg, A.P., and Vogelstein, B. (1984). A technique for radio-labeling DNA restriction endonuclease fragments to high specific activity. Addendum. Anal. Biochem. 137, 266-267.
14. Fuchs, E. (1990). Epidermal differentiation: the bare essentials. J. Cell Biol 111, 2807-2814.
15. Hendricks-Taylor, L.R., Bachinski, L.L., Siciliano, M.J., Fertitta, A., Trask, B., de Jong, P.J., Ledbetter, D.H., and Darlington, G.J. (1992). The CCAAT/Enhancer binding protein (C/EBP alpha) gene (CEBPA) maps to human chromosome 19q13.1 and the related nuclear factor NF-IL6 (C/EBP beta) gene (CEBPB) maps to human chromosome 20q13.1 Genomics 14, 12-17.
16. Landschulz, W.H., Johnson, P.F., Adashi, E.Y., Graves, B.J., and McKnight, S.L. (1988a). Isolation of a recombinant copy of the gene encoding C/EBP. Genes Dev. 2, 786-800.
17. Landschulz, W.H., Johnson, P.F., and McKnight, S.L. (1988b). The Leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240, 1759-1764.
18. Lin, F.-T., MacDougald, O.A., Diehl, A.M., and Lane, M.D. (1996). A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. Proc. Natl. Acad. Sci. USA 90, 9606-9610.
19. Lincoln, A.J., Williams, S.C., and Johnson, P.F. (1994). A revised sequence of the rat c/ebp gene. Genes Dev. 8, 1131-1132.
20. McMaster, G.K., and Carmichael, G.G. (1977). Analysis of single and double-stranded nucleic acids on polyacrylamide and agarose gels using glyoxal and acridine orange. Proc. Natl. Acad. Sci. USA 74, 4835-4838.
21. Molhuizen, H.O.F., Alkemade, H.A.C., Zeeuwen, P.L.J.M., de Jongh, G.J., Wieringa, B., and Schalkwijk, J. (1993). SKALP/ Elafin: an elastase inhibitorfrom cultured human keratinocytes. Purification, cDNA sequence and evidence for transglutaminase crosslinking. J. Biol. Chem. 268, 12028-12032.
22. Ossipow, V., Descombes, P., and Schibler, U. (1993). CCAAT/enhancer binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc. Natl. Acad. Sci. USA 90, 8219-8223.
23. Pearson, W.R., and Lipman, D.J. (1988). Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA 85, 2444-2448.
24. Rheinwald, J.G., and Green, H. (1975). Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 6, 331-344.
25. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989). Molecular cloning - a Laboratory Manual (Cold Spring Harbor, NY, USA: Cold Spring Harbor Laboratory Press).
26. Sanger, F., Coulson, A.R., Barrell, B.G., Smith, A.J.H., and Roe, B.A. (1980). Cloning in single-stranded bacteriophage as an aid to rapid sequencing. J. Mol. Biol. 143, 161-178.
27. Siegenthaler, G., Hotz, R., Chatellard-Gruaz, D., Didierjean, L., Hellman, U., and Saurat, J.H. (1996). Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro. Biochem. J. 302, 363-371.
28. Umek, R.M., Friedman, A.D., and McKnight, S.L. (1991). CCAAT-Enhancer binding protein: a component of a differentiation switch. Science 251, 288-292.
29. van Ruissen, F., van Erp, P.E.J., de Jongh, G.J., Boezeman, J.B.M., van de Kerkhof, P.C.M., and Schalkwijk, J. (1994). Cell kinetic characterization of growth arrest in cultured human keratinocytes. J. Cell Sci. 107, 2219-2228.
30. Wang, N., Finegold, M.J., Bradley, A., Ou, C.N., Abdelsayed, S.V., Wilde, M.D., Taylor, L.R., Wilson, D.R., and Darlington, G.J. (1995). Impaired energy homeostasis in C/EBP-alpha knockout mice. Science 269, 1108-1112.
31. Williams, S.C., Cantwell, C.A., and Johnson, P.F. (1991). A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro. Genes Dev. 5, 1553-1567.
32. Xu, Q., and Tata, J.R. (1992). Characterization and developmental expression of Xenopus C/EBP gene. Mech. Dev. 38, 69-81.