The crucial role of IL-2/IL-2RA-mediated immune regulation in the pathogenesis of type 1 diabetes, an evidence coming from genetic and animal model studies

Immunology Letters

Volumn 118, Issue 1, 2008, Pages 1-5

  Chistiakov, Dimitry A ^a,b   Voronova, Natalia V ^b   Chistiakov, Pavel A ^c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b STATE RESEARCH INSTITUTE OF GENETICS AND SELECTION OF INDUSTRIAL MICROORGANISMS   (Russian Federation)

^c N N BLOKHIN NATIONAL MEDICAL RESEARCH CENTER OF ONCOLOGY   (Russian Federation)

Author keywords

Autoimmunity; Interleukin 2; Interleukin 2 receptor; Susceptibility; Type 1 diabetes

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ CD25+ T LYMPHOCYTE; CHROMOSOME 10P; CHROMOSOME 4Q; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; EVIDENCE BASED MEDICINE; GENE LOCUS; HUMAN; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-2; RECEPTORS, INTERLEUKIN-2; SIGNAL TRANSDUCTION;

EID: 43849113797     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2008.03.002     Document Type: Review

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