-
1
-
-
0016492887
-
Symposium. Crohn's disease: Anal lesions
-
Lockhart-Mummery HE. Symposium. Crohn's disease: Anal lesions. Dis Colon Rectum 1975 18 : 200 2.
-
(1975)
Dis Colon Rectum
, vol.18
, pp. 200-2
-
-
Lockhart-Mummery, H.E.1
-
2
-
-
2442661318
-
Review article: The medical treatment of Crohn's perianal fistulas
-
Schwartz DA, Herdman CR. Review article: The medical treatment of Crohn's perianal fistulas. Aliment Pharmacol Ther 2004 19 : 953 67.
-
(2004)
Aliment Pharmacol Ther
, vol.19
, pp. 953-67
-
-
Schwartz, D.A.1
Herdman, C.R.2
-
3
-
-
0018903830
-
Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease
-
Hellers G, Bergstrand O, Ewerth S, et al. Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease. Gut 1980 21 : 525 7.
-
(1980)
Gut
, vol.21
, pp. 525-7
-
-
Hellers, G.1
Bergstrand, O.2
Ewerth, S.3
-
4
-
-
0036207249
-
The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota
-
Schwartz DA, Loftus EV Jr., Tremaine WJ, et al. The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota. Gastroenterology 2002 122 : 875 80.
-
(2002)
Gastroenterology
, vol.122
, pp. 875-80
-
-
Schwartz, D.A.1
Loftus Jr., E.V.2
Tremaine, W.J.3
-
6
-
-
33144463875
-
European Crohn's and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohn's disease: Special situations
-
Caprilli R, Gassull MA, Escher JC, et al. European Crohn's and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohn's disease: Special situations. Gut 2006 55 (Suppl 1 I36 58.
-
(2006)
Gut
, vol.55
, Issue.1
-
-
Caprilli, R.1
Gassull, M.A.2
Escher, J.C.3
-
7
-
-
0345802756
-
Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease
-
Dejaco C, Harrer M, Waldhoer T, et al. Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. Aliment Pharmacol Ther 2003 18 : 1113 20.
-
(2003)
Aliment Pharmacol Ther
, vol.18
, pp. 1113-20
-
-
Dejaco, C.1
Harrer, M.2
Waldhoer, T.3
-
8
-
-
0019977612
-
Metronidazole therapy for perineal Crohn's disease: A follow-up study
-
Brandt LJ, Bernstein LH, Boley SJ, et al. Metronidazole therapy for perineal Crohn's disease: A follow-up study. Gastroenterology 1982 83 : 383 7.
-
(1982)
Gastroenterology
, vol.83
, pp. 383-7
-
-
Brandt, L.J.1
Bernstein, L.H.2
Boley, S.J.3
-
9
-
-
0021264732
-
Metronidazole therapy for Crohn's disease and associated fistulae
-
Jakobovits J, Schuster MM. Metronidazole therapy for Crohn's disease and associated fistulae. Am J Gastroenterol 1984 79 : 533 40.
-
(1984)
Am J Gastroenterol
, vol.79
, pp. 533-40
-
-
Jakobovits, J.1
Schuster, M.M.2
-
10
-
-
0000950585
-
Long-term outcome of ciprofloxacine treatment in severe perianal or fistulous Crohn's disease [abstract]
-
Turunen U, Farkkila M, Valtonen V. Long-term outcome of ciprofloxacine treatment in severe perianal or fistulous Crohn's disease [abstract]. Gastroenterology 1993 104 : A793.
-
(1993)
Gastroenterology
, vol.104
-
-
Turunen, U.1
Farkkila, M.2
Valtonen, V.3
-
11
-
-
0035923424
-
Diagnosis and treatment of perianal fistulas in Crohn's disease
-
Schwartz DA, Pemberton JH, Sandborn WJ. Diagnosis and treatment of perianal fistulas in Crohn's disease. Ann Intern Med 2001 135 : 906 18.
-
(2001)
Ann Intern Med
, vol.135
, pp. 906-18
-
-
Schwartz, D.A.1
Pemberton, J.H.2
Sandborn, W.J.3
-
12
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001 411 : 599 603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
13
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001 411 : 603 6.
-
(2001)
Nature
, vol.411
, pp. 603-6
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
-
14
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a working party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a working party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005 19 (Suppl A 5 36.
-
(2005)
Can J Gastroenterol
, vol.19
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
15
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, et al. Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003 278 : 5509 12.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-12
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
-
16
-
-
0012722659
-
NOD2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, Boneca IG, Viala J, et al. NOD2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 2003 278 : 8869 72.
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-72
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
-
17
-
-
33745536739
-
Functional consequences of NOD2 (CARD15) mutations
-
Abraham C, Cho JH. Functional consequences of NOD2 (CARD15) mutations. Inflamm Bowel Dis 2006 12 : 641 50.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 641-50
-
-
Abraham, C.1
Cho, J.H.2
-
18
-
-
29144483937
-
Reduced Paneth cell alpha-defensins in ileal Crohn's disease
-
Wehkamp J, Salzman NH, Porter E, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proc Natl Acad Sci U S A 2005 102 : 18129 34.
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, pp. 18129-34
-
-
Wehkamp, J.1
Salzman, N.H.2
Porter, E.3
-
19
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha defensin expression
-
Wehkamp J, Harder J, Weichenthal M, et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha defensin expression. Gut 2004 53 : 1658 64.
-
(2004)
Gut
, vol.53
, pp. 1658-64
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
-
21
-
-
0036318272
-
Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease
-
Wehkamp J, Fellermann K, Herrlinger KR, et al. Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease. Eur J Gastroenterol Hepatol 2002 14 : 745 52.
-
(2002)
Eur J Gastroenterol Hepatol
, vol.14
, pp. 745-52
-
-
Wehkamp, J.1
Fellermann, K.2
Herrlinger, K.R.3
-
22
-
-
0042387792
-
Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster
-
Hollox EJ, Armour JA, Barber JC. Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster. Am J Hum Genet 2003 73 : 591 600.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 591-600
-
-
Hollox, E.J.1
Armour, J.A.2
Barber, J.C.3
-
23
-
-
33748558056
-
A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn's disease of the colon
-
Fellermann K, Stange DE, Schaeffeler E, et al. A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn's disease of the colon. Am J Hum Genet 2006 79 : 439 48.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 439-48
-
-
Fellermann, K.1
Stange, D.E.2
Schaeffeler, E.3
-
24
-
-
33144468326
-
European Crohn's and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
-
Stange EF, Travis SP, Vermeire S, et al. European Crohn's and Colitis Organisation. European evidence based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis. Gut 2006 55 (Suppl 1 I1 15.
-
(2006)
Gut
, vol.55
, Issue.1
-
-
Stange, E.F.1
Travis, S.P.2
Vermeire, S.3
-
25
-
-
0018888679
-
Treatment of Crohn's disease with 6-mercaptopurine: A long-term, randomized double-blind study
-
Present DH, Korelitz BI, Wisch N, et al. Treatment of Crohn's disease with 6-mercaptopurine: A long-term, randomized double-blind study. N Engl J Med 1980 302 : 981 7.
-
(1980)
N Engl J Med
, vol.302
, pp. 981-7
-
-
Present, D.H.1
Korelitz, B.I.2
Wisch, N.3
-
26
-
-
0021969487
-
Favorable effect of 6-MP on fistulae of Crohn's disease
-
Korelitz BI, Present DH. Favorable effect of 6-MP on fistulae of Crohn's disease. Dig Dis Sci 1985 30 : 58 64.
-
(1985)
Dig Dis Sci
, vol.30
, pp. 58-64
-
-
Korelitz, B.I.1
Present, D.H.2
-
27
-
-
0033529049
-
Infliximab for the treatment of fistulas in patients with Crohn's disease
-
Present DH, Rutgeerts P, Targan S, et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999 340 : 1398 405.
-
(1999)
N Engl J Med
, vol.340
, pp. 1398-405
-
-
Present, D.H.1
Rutgeerts, P.2
Targan, S.3
-
28
-
-
0037062228
-
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: A cohort study
-
Hampe J, Grebe J, Nikolaus S, et al. Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: A cohort study. Lancet 2002 359 : 1661 5.
-
(2002)
Lancet
, vol.359
, pp. 1661-5
-
-
Hampe, J.1
Grebe, J.2
Nikolaus, S.3
-
29
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
Zanger UM, Raimundo S, Eichelbaum M. Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry. Naunyn Schmiedebergs Arch Pharmakol 2004 369 : 23 37.
-
(2004)
Naunyn Schmiedebergs Arch Pharmakol
, vol.369
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
-
30
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
Kuehl P, Zhang J, Lin Y, et al. Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet 2001 27 : 383 91.
-
(2001)
Nat Genet
, vol.27
, pp. 383-91
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
-
31
-
-
0036277684
-
Point: Population stratification: A problem for case-control studies of candidate-gene associations?
-
Thomas DC, Witte JS. Point: Population stratification: A problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev 2002 11 : 505 12.
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 505-12
-
-
Thomas, D.C.1
Witte, J.S.2
-
32
-
-
0037342213
-
Candidate gene case-control studies
-
Daly AK. Candidate gene case-control studies. Pharmacogenomics 2003 4 : 127 39.
-
(2003)
Pharmacogenomics
, vol.4
, pp. 127-39
-
-
Daly, A.K.1
-
33
-
-
4143049054
-
Lipid-lowering response to statins is affected by CYP3A5 polymorphism
-
Kivisto KT, Niemi M, Schaeffeler E, et al. Lipid-lowering response to statins is affected by CYP3A5 polymorphism. Pharmacogenetics 2004 14 : 523 5.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 523-5
-
-
Kivisto, K.T.1
Niemi, M.2
Schaeffeler, E.3
-
34
-
-
0036161216
-
A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease
-
Sandborn WJ, Feagan BG, Hanauer SB, et al. A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease. Gastroenterology 2002 122 : 512 30.
-
(2002)
Gastroenterology
, vol.122
, pp. 512-30
-
-
Sandborn, W.J.1
Feagan, B.G.2
Hanauer, S.B.3
-
35
-
-
0031990995
-
The role of the fecal stream in Crohn's disease: A historical and analytic review
-
Janowitz HD, Croen EC, Sachar DB. The role of the fecal stream in Crohn's disease: A historical and analytic review. Inflamm Bowel Dis 1998 4 : 29 39.
-
(1998)
Inflamm Bowel Dis
, vol.4
, pp. 29-39
-
-
Janowitz, H.D.1
Croen, E.C.2
Sachar, D.B.3
-
36
-
-
0033736428
-
Effect of fecal diversion alone on perianal Crohn's disease
-
discussion 1262-3.
-
Yamamoto T, Allan RN, Keighley MR. Effect of fecal diversion alone on perianal Crohn's disease. World J Surg 2000 24 : 1258 62 discussion 1262-3.
-
(2000)
World J Surg
, vol.24
, pp. 1258-62
-
-
Yamamoto, T.1
Allan, R.N.2
Keighley, M.R.3
-
38
-
-
0041665068
-
Tacrolimus for the treatment of fistulas in patients with Crohn's disease: A randomized, placebo-controlled trial
-
Sandborn WJ, Present HD, Isaacs KL, et al. Tacrolimus for the treatment of fistulas in patients with Crohn's disease: A randomized, placebo-controlled trial. Gastroenterology 2003 125 : 380 8.
-
(2003)
Gastroenterology
, vol.125
, pp. 380-8
-
-
Sandborn, W.J.1
Present, H.D.2
Isaacs, K.L.3
-
39
-
-
13244292161
-
NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, et al. NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005 307 : 731 4.
-
(2005)
Science
, vol.307
, pp. 731-4
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
-
40
-
-
0033214433
-
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense
-
Wilson CL, Ouellette AJ, Satchell DP, et al. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense. Science 1999 286 : 113 7.
-
(1999)
Science
, vol.286
, pp. 113-7
-
-
Wilson, C.L.1
Ouellette, A.J.2
Satchell, D.P.3
-
41
-
-
0037417311
-
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
-
Salzman NH, Ghosh D, Huttner KM, et al. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin. Nature 2003 422 : 522 6.
-
(2003)
Nature
, vol.422
, pp. 522-6
-
-
Salzman, N.H.1
Ghosh, D.2
Huttner, K.M.3
-
42
-
-
0031758230
-
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
-
Darfeuille-Michaud A, Neut C, Barnich N, et al. Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease. Gastroenterology 1998 115 : 1405 13.
-
(1998)
Gastroenterology
, vol.115
, pp. 1405-13
-
-
Darfeuille-Michaud, A.1
Neut, C.2
Barnich, N.3
-
44
-
-
4143069158
-
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
-
Darfeuille-Michaud A, Boudeau J, Bulois P, et al. High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology 2004 127 : 412 21.
-
(2004)
Gastroenterology
, vol.127
, pp. 412-21
-
-
Darfeuille-Michaud, A.1
Boudeau, J.2
Bulois, P.3
-
45
-
-
0345830652
-
Dysbiosis in inflammatory bowel disease
-
Guarantor of the article: Walter Reinisch, M.D. Specific author contributions: S. Angelberger was involved in the data collection, data analysis, and manuscript writing; Walter Reinisch was involved in the study design and manuscript writing; S. Angelberger, Walter Reinisch, C. Dejaco, W. Miehsler, and H. Vogelsang were the clinical investigators; T. Waldhoer was involved in the statistical analysis; J. Wehkamp was involved in the genetic analysis; C. Lichtenberger was involved in the lab analysis; E. Schaeffeler was involved in the genetic/statistical analysis; M. Schwab was involved in the study design, financial support, and manuscript writing; and A. Teml was involved in the study design, statistical analysis, and manuscript writing. Financial support: This study was supported by the grant "Jubilä umsfonds der Österreichischen Nationalbank, Nr. 9358."
-
Tamboli CP, Neut C, Desreumaux P, et al. Dysbiosis in inflammatory bowel disease. Gut 2004 53 : 1 4.
-
(2004)
Gut
, vol.53
, pp. 1-4
-
-
Tamboli, C.P.1
Neut, C.2
Desreumaux, P.3
|