-
1
-
-
0035124607
-
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia
-
Barone F. C., Irving E. A., Ray A. M. et al. (2001) Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia. Med. Res. Rev. 21, 129 145.
-
(2001)
Med. Res. Rev.
, vol.21
, pp. 129-145
-
-
Barone, F.C.1
Irving, E.A.2
Ray, A.M.3
-
2
-
-
0037119464
-
P38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcription factor-2
-
Bhat N. R., Feinstein D. L., Shen Q. Bhat A. N. (2002) p38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcription factor-2. J. Biol. Chem. 277, 29584 29592.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29584-29592
-
-
Bhat, N.R.1
Feinstein, D.L.2
Shen, Q.3
Bhat, A.N.4
-
3
-
-
0027197996
-
Neuroprotective role of IL-4 against activated microglia
-
Chao C. C., Molitor T. W. Hu S. (1993) Neuroprotective role of IL-4 against activated microglia. J. Immunol. 151, 1473 1481.
-
(1993)
J. Immunol.
, vol.151
, pp. 1473-1481
-
-
Chao, C.C.1
Molitor, T.W.2
Hu, S.3
-
4
-
-
0035900675
-
P38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells
-
Cheng A., Chan S. L., Milhavet O., Wang S. Mattson M. P. (2001) p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells. J. Biol. Chem. 276, 43320 43327.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43320-43327
-
-
Cheng, A.1
Chan, S.L.2
Milhavet, O.3
Wang, S.4
Mattson, M.P.5
-
5
-
-
2442502511
-
Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons
-
Choi W. S., Eom D. S., Han B. S., Kim W. K., Han B. H., Choi E. J., Oh T. H., Markelonis G. J., Cho J. W. Oh Y. J. (2004) Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons. J. Biol. Chem. 279, 20451 20460.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20451-20460
-
-
Choi, W.S.1
Eom, D.S.2
Han, B.S.3
Kim, W.K.4
Han, B.H.5
Choi, E.J.6
Oh, T.H.7
Markelonis, G.J.8
Cho, J.W.9
Oh, Y.J.10
-
6
-
-
0038538477
-
Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38
-
Clark A. R., Dean J. L. Saklatvala J. (2003) Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38. FEBS Lett. 546, 37 44.
-
(2003)
FEBS Lett.
, vol.546
, pp. 37-44
-
-
Clark, A.R.1
Dean, J.L.2
Saklatvala, J.3
-
7
-
-
33747632142
-
MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease
-
Culbert A. A., Skaper S. D., Howlett D. R., Evans N. A., Facci L., Soden P. E., Seymour Z. M., Guillot F., Gaestel M. Richardson J. C. (2006) MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease. J. Biol. Chem. 281, 23658 23667.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23658-23667
-
-
Culbert, A.A.1
Skaper, S.D.2
Howlett, D.R.3
Evans, N.A.4
Facci, L.5
Soden, P.E.6
Seymour, Z.M.7
Guillot, F.8
Gaestel, M.9
Richardson, J.C.10
-
8
-
-
0030712362
-
Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes
-
Da Silva J., Pierrat B., Mary J. L. Lesslauer W. (1997) Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes. J. Biol. Chem. 272, 28373 28380.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28373-28380
-
-
Da Silva, J.1
Pierrat, B.2
Mary, J.L.3
Lesslauer, W.4
-
9
-
-
3142546235
-
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation
-
Dean J. L., Sully G., Clark A. R. Saklatvala J. (2004) The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. Cell. Signal. 16, 1113 1121.
-
(2004)
Cell. Signal.
, vol.16
, pp. 1113-1121
-
-
Dean, J.L.1
Sully, G.2
Clark, A.R.3
Saklatvala, J.4
-
10
-
-
0035807904
-
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
-
Du Y., Ma Z., Lin S. et al. (2001) Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Proc. Natl Acad. Sci. USA 98, 14669 14674.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 14669-14674
-
-
Du, Y.1
Ma, Z.2
Lin, S.3
-
11
-
-
21744442278
-
Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene
-
Fechir M., Linker K., Pautz A., Hubrich T., Forstermann U., Rodriguez-Pascual F. Kleinert H. (2005) Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene. Mol. Pharmacol. 67, 2148 2161.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 2148-2161
-
-
Fechir, M.1
Linker, K.2
Pautz, A.3
Hubrich, T.4
Forstermann, U.5
Rodriguez-Pascual, F.6
Kleinert, H.7
-
12
-
-
2542475349
-
Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum
-
Ferger B., Leng A., Mura A., Hengerer B. Feldon J. (2004) Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. J. Neurochem. 89, 822 833.
-
(2004)
J. Neurochem.
, vol.89
, pp. 822-833
-
-
Ferger, B.1
Leng, A.2
Mura, A.3
Hengerer, B.4
Feldon, J.5
-
13
-
-
0029664477
-
CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells
-
Galea E., Reis D. J., Fox E. S., Xu H. Feinstein D. L. (1996) CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells. J. Neuroimmunol. 64, 19 28.
-
(1996)
J. Neuroimmunol.
, vol.64
, pp. 19-28
-
-
Galea, E.1
Reis, D.J.2
Fox, E.S.3
Xu, H.4
Feinstein, D.L.5
-
14
-
-
0038044029
-
Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons
-
Gao H. M., Liu B. Hong J. S. (2003) Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons. J. Neurosci. 23, 6181 6187.
-
(2003)
J. Neurosci.
, vol.23
, pp. 6181-6187
-
-
Gao, H.M.1
Liu, B.2
Hong, J.S.3
-
15
-
-
0034710303
-
P38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons
-
Ghatan S., Larner S., Kinoshita Y., Hetman M., Patel L., Xia Z., Youle R. J. Morrison R. S. (2000) p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J. Cell Biol. 150, 335 347.
-
(2000)
J. Cell Biol.
, vol.150
, pp. 335-347
-
-
Ghatan, S.1
Larner, S.2
Kinoshita, Y.3
Hetman, M.4
Patel, L.5
Xia, Z.6
Youle, R.J.7
Morrison, R.S.8
-
16
-
-
0032919249
-
An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons
-
Harada J. Sugimoto M. (1999) An inhibitor of p38 and JNK MAP kinases prevents activation of caspase and apoptosis of cultured cerebellar granule neurons. Jpn. J. Pharmacol. 79, 369 378.
-
(1999)
Jpn. J. Pharmacol.
, vol.79
, pp. 369-378
-
-
Harada, J.1
Sugimoto, M.2
-
17
-
-
0035895994
-
Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons
-
Harding T. C., Xue L., Bienemann A., Haywood D., Dickens M., Tolkovsky A. M. Uney J. B. (2001) Inhibition of JNK by overexpression of the JNL binding domain of JIP-1 prevents apoptosis in sympathetic neurons. J. Biol. Chem. 276, 4531 4534.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 4531-4534
-
-
Harding, T.C.1
Xue, L.2
Bienemann, A.3
Haywood, D.4
Dickens, M.5
Tolkovsky, A.M.6
Uney, J.B.7
-
18
-
-
33644753147
-
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element
-
Hitti E., Iakovleva T., Brook M., Deppenmeier S., Gruber A. D., Radzioch D., Clark A. R., Blackshear P. J., Kotlyarov A. Gaestel M. (2006) Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element. Mol. Cell. Biol. 26, 2399 2407.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2399-2407
-
-
Hitti, E.1
Iakovleva, T.2
Brook, M.3
Deppenmeier, S.4
Gruber, A.D.5
Radzioch, D.6
Clark, A.R.7
Blackshear, P.J.8
Kotlyarov, A.9
Gaestel, M.10
-
19
-
-
0036275058
-
P38 MAP kinase is involved in lipopolysaccharide-induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures
-
Jeohn G. H., Cooper C. L., Wilson B., Chang R. C., Jang K. J., Kim H. C., Liu B. Hong J. S. (2002) p38 MAP kinase is involved in lipopolysaccharide- induced dopaminergic neuronal cell death in rat mesencephalic neuron-glia cultures. Ann. NY Acad. Sci. 962, 332 346.
-
(2002)
Ann. NY Acad. Sci.
, vol.962
, pp. 332-346
-
-
Jeohn, G.H.1
Cooper, C.L.2
Wilson, B.3
Chang, R.C.4
Jang, K.J.5
Kim, H.C.6
Liu, B.7
Hong, J.S.8
-
20
-
-
3843051149
-
Regulatory roles of JNK in programmed cell death
-
Kanda H. Miura M. (2004) Regulatory roles of JNK in programmed cell death. J. Biochem. 136, 1 6.
-
(2004)
J. Biochem.
, vol.136
, pp. 1-6
-
-
Kanda, H.1
Miura, M.2
-
21
-
-
0037121941
-
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease
-
Kontoyiannis D., Boulougouris G., Manoloukos M. et al. (2002) Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease. J. Exp. Med. 196, 1563 1574.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1563-1574
-
-
Kontoyiannis, D.1
Boulougouris, G.2
Manoloukos, M.3
-
22
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A., Neininger A., Schubert C., Eckert R., Birchmeier C., Volk H. D. Gaestel M. (1999) MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1, 94 97.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
Gaestel, M.7
-
23
-
-
0036273201
-
Distinct cellular functions of MK2
-
Kotlyarov A., Yannoni Y., Fritz S., Laass K., Telliez J. B., Pitman D., Lin L. L. Gaestel M. (2002) Distinct cellular functions of MK2. Mol. Cell. Biol. 22, 4827 4835.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4827-4835
-
-
Kotlyarov, A.1
Yannoni, Y.2
Fritz, S.3
Laass, K.4
Telliez, J.B.5
Pitman, D.6
Lin, L.L.7
Gaestel, M.8
-
24
-
-
0027298505
-
Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
-
Lee S. C., Liu W., Dickson D. W., Brosnan C. F. Berman J. W. (1993) Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J. Immunol. 150, 2659 2667.
-
(1993)
J. Immunol.
, vol.150
, pp. 2659-2667
-
-
Lee, S.C.1
Liu, W.2
Dickson, D.W.3
Brosnan, C.F.4
Berman, J.W.5
-
25
-
-
7244242682
-
Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co-cultures
-
Lee S. M., Yune T. Y., Kim S. J., Kim Y. C., Oh Y. J., Markelonis G. J. Oh T. H. (2004) Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co-cultures. J. Neurochem. 91, 568 578.
-
(2004)
J. Neurochem.
, vol.91
, pp. 568-578
-
-
Lee, S.M.1
Yune, T.Y.2
Kim, S.J.3
Kim, Y.C.4
Oh, Y.J.5
Markelonis, G.J.6
Oh, T.H.7
-
26
-
-
0036569435
-
Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection
-
Lehner M. D., Schwoebel F., Kotlyarov A., Leist M., Gaestel M. Hartung T. (2002) Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection. J. Immunol. 168, 4667 4673.
-
(2002)
J. Immunol.
, vol.168
, pp. 4667-4673
-
-
Lehner, M.D.1
Schwoebel, F.2
Kotlyarov, A.3
Leist, M.4
Gaestel, M.5
Hartung, T.6
-
27
-
-
0032710609
-
Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease
-
Liberatore G. T., Jackson-Lewis V., Vukosavic S., Mandir A. S., Vila M., McAuliffe W. G., Dawson V. L., Dawson T. M. Przedborski S. (1999) Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nat. Med. 5, 1403 1409.
-
(1999)
Nat. Med.
, vol.5
, pp. 1403-1409
-
-
Liberatore, G.T.1
Jackson-Lewis, V.2
Vukosavic, S.3
Mandir, A.S.4
Vila, M.5
McAuliffe, W.G.6
Dawson, V.L.7
Dawson, T.M.8
Przedborski, S.9
-
28
-
-
0034015558
-
Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation
-
Liu B., Du L. Hong J. S. (2000) Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation. J. Pharmacol. Exp. Ther. 293, 607 617.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 607-617
-
-
Liu, B.1
Du, L.2
Hong, J.S.3
-
29
-
-
0031874792
-
Inflammation in the CNS: Balance between immunological privilege and immune responses
-
Matyszak M. K. (1998) Inflammation in the CNS: balance between immunological privilege and immune responses. Prog. Neurobiol. 56, 19 35.
-
(1998)
Prog. Neurobiol.
, vol.56
, pp. 19-35
-
-
Matyszak, M.K.1
-
30
-
-
0034281386
-
Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase
-
Namgung U. Xia Z. (2000) Arsenite-induced apoptosis in cortical neurons is mediated by c-Jun N-terminal protein kinase 3 and p38 mitogen-activated protein kinase. J. Neurosci. 20, 6442 6451.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6442-6451
-
-
Namgung, U.1
Xia, Z.2
-
31
-
-
0036479125
-
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels
-
Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., Volk H. D., Holtmann H., Kollias G. Gaestel M. (2002) MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels. J. Biol. Chem. 277, 3065 3068.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3065-3068
-
-
Neininger, A.1
Kontoyiannis, D.2
Kotlyarov, A.3
Winzen, R.4
Eckert, R.5
Volk, H.D.6
Holtmann, H.7
Kollias, G.8
Gaestel, M.9
-
32
-
-
0032936755
-
Etiology and pathogenesis of Parkinson's disease
-
Olanow C. W. Tatton W. G. (1999) Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci. 22, 123 144.
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 123-144
-
-
Olanow, C.W.1
Tatton, W.G.2
-
33
-
-
14644446028
-
2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids
-
2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids. Mol. Cell. Neurosci. 28, 452 461.
-
(2005)
Mol. Cell. Neurosci.
, vol.28
, pp. 452-461
-
-
Onyango, I.G.1
Tuttle, J.B.2
Bennett Jr., J.P.3
-
34
-
-
0029942444
-
Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: A stereological study using the cavalieri and optical disector methods
-
Oorschot D. E. (1996) Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: a stereological study using the cavalieri and optical disector methods. J. Comp. Neurol. 366, 580 599.
-
(1996)
J. Comp. Neurol.
, vol.366
, pp. 580-599
-
-
Oorschot, D.E.1
-
35
-
-
33644958235
-
Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells
-
Ouyang M. Shen X. (2006) Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells. J. Neurochem. 97, 234 244.
-
(2006)
J. Neurochem.
, vol.97
, pp. 234-244
-
-
Ouyang, M.1
Shen, X.2
-
36
-
-
0025964041
-
The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method
-
Pakkenberg B., Moller A., Gundersen H. J., Mouritzen Dam A. Pakkenberg H. (1991) The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method. J. Neurol. Neurosurg. Psychiatr. 54, 30 33.
-
(1991)
J. Neurol. Neurosurg. Psychiatr.
, vol.54
, pp. 30-33
-
-
Pakkenberg, B.1
Moller, A.2
Gundersen, H.J.3
Mouritzen Dam, A.4
Pakkenberg, H.5
-
37
-
-
0033771987
-
Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: In vitro and in vivo studies
-
Possel H., Noack H., Putzke J., Wolf G. Sies H. (2000) Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies. Glia 32, 51 59.
-
(2000)
Glia
, vol.32
, pp. 51-59
-
-
Possel, H.1
Noack, H.2
Putzke, J.3
Wolf, G.4
Sies, H.5
-
38
-
-
0029984860
-
Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
-
Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V. L. Dawson T. M. (1996) Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proc. Natl Acad. Sci. USA 93, 4565 4571.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4565-4571
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Yokoyama, R.3
Shibata, T.4
Dawson, V.L.5
Dawson, T.M.6
-
39
-
-
0346463000
-
NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
-
Qin L., Liu Y., Wang T., Wei S. J., Block M. L., Wilson B., Liu B. Hong J. S. (2004) NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J. Biol. Chem. 279, 1415 1421.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 1415-1421
-
-
Qin, L.1
Liu, Y.2
Wang, T.3
Wei, S.J.4
Block, M.L.5
Wilson, B.6
Liu, B.7
Hong, J.S.8
-
40
-
-
0034714259
-
Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR
-
Rodriguez-Pascual F., Hausding M., Ihrig-Biedert I., Furneaux H., Levy A. P., Forstermann U. Kleinert H. (2000) Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR. J. Biol. Chem. 275, 26040 26049.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26040-26049
-
-
Rodriguez-Pascual, F.1
Hausding, M.2
Ihrig-Biedert, I.3
Furneaux, H.4
Levy, A.P.5
Forstermann, U.6
Kleinert, H.7
-
41
-
-
0030972777
-
Astrogliosis in the neonatal and adult murine brain post-trauma: Elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma
-
Rostworowski M., Balasingam V., Chabot S., Owens T. Yong V. W. (1997) Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma. J. Neurosci. 17, 3664 3674.
-
(1997)
J. Neurosci.
, vol.17
, pp. 3664-3674
-
-
Rostworowski, M.1
Balasingam, V.2
Chabot, S.3
Owens, T.4
Yong, V.W.5
-
42
-
-
0028022750
-
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
-
Rouse J., Cohen P., Trigon S., Morange M., Alonso-Llamazares A., Zamanillo D., Hunt T. Nebreda A. R. (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78, 1027 1037.
-
(1994)
Cell
, vol.78
, pp. 1027-1037
-
-
Rouse, J.1
Cohen, P.2
Trigon, S.3
Morange, M.4
Alonso-Llamazares, A.5
Zamanillo, D.6
Hunt, T.7
Nebreda, A.R.8
-
43
-
-
33745269269
-
Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection
-
Ruano D., Revilla E., Gavilan M. P., Vizuete M. L., Pintado C., Vitorica J. Castano A. (2006) Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection. Neuroscience 140, 1157 1168.
-
(2006)
Neuroscience
, vol.140
, pp. 1157-1168
-
-
Ruano, D.1
Revilla, E.2
Gavilan, M.P.3
Vizuete, M.L.4
Pintado, C.5
Vitorica, J.6
Castano, A.7
-
44
-
-
0028364659
-
Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue
-
Shohami E., Novikov M., Bass R., Yamin A. Gallily R. (1994) Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue. J. Cereb. Blood Flow Metab. 14, 615 619.
-
(1994)
J. Cereb. Blood Flow Metab.
, vol.14
, pp. 615-619
-
-
Shohami, E.1
Novikov, M.2
Bass, R.3
Yamin, A.4
Gallily, R.5
-
45
-
-
0141672049
-
P38 MAP kinase is activated at early stages in Alzheimer's disease brain
-
Sun A., Liu M., Nguyen X. V. Bing G. (2003) P38 MAP kinase is activated at early stages in Alzheimer's disease brain. Exp. Neurol. 183, 394 405.
-
(2003)
Exp. Neurol.
, vol.183
, pp. 394-405
-
-
Sun, A.1
Liu, M.2
Nguyen, X.V.3
Bing, G.4
-
46
-
-
0038641723
-
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration
-
Teismann P., Tieu K., Choi D. K., Wu D. C., Naini A., Hunot S., Vila M., Jackson-Lewis V. Przedborski S. (2003) Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc. Natl Acad. Sci. USA 100, 5473 5478.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 5473-5478
-
-
Teismann, P.1
Tieu, K.2
Choi, D.K.3
Wu, D.C.4
Naini, A.5
Hunot, S.6
Vila, M.7
Jackson-Lewis, V.8
Przedborski, S.9
-
47
-
-
33846436077
-
Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion
-
Timmer M., Cesnulevicius K., Winkler C., Kolb J., Lipokatic-Takacs E., Jungnickel J. Grothe C. (2007) Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion. J. Neurosci. 27, 459 471.
-
(2007)
J. Neurosci.
, vol.27
, pp. 459-471
-
-
Timmer, M.1
Cesnulevicius, K.2
Winkler, C.3
Kolb, J.4
Lipokatic-Takacs, E.5
Jungnickel, J.6
Grothe, C.7
-
48
-
-
0027504297
-
Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
-
Tipton K. F. Singer T. P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem. 61, 1191 1206.
-
(1993)
J. Neurochem.
, vol.61
, pp. 1191-1206
-
-
Tipton, K.F.1
Singer, T.P.2
-
49
-
-
33748743781
-
Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress
-
Vertii A., Hakim C., Kotlyarov A. Gaestel M. (2006) Analysis of properties of small heat shock protein Hsp25 in MAPK-activated protein kinase 2 (MK2)-deficient cells: MK2-dependent insolubilization of Hsp25 oligomers correlates with susceptibility to stress. J. Biol. Chem. 281, 26966 26975.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26966-26975
-
-
Vertii, A.1
Hakim, C.2
Kotlyarov, A.3
Gaestel, M.4
-
50
-
-
33644625777
-
Brain inflammation in epilepsy: Experimental and clinical evidence
-
Vezzani A. Granata T. (2005) Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 46, 1724 1743.
-
(2005)
Epilepsia
, vol.46
, pp. 1724-1743
-
-
Vezzani, A.1
Granata, T.2
-
51
-
-
0035956874
-
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
-
Vila M., Jackson-Lewis V., Vukosavic S., Djaldetti R., Liberatore G., Offen D., Korsmeyer S. J. Przedborski S. (2001) Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease. Proc. Natl Acad. Sci. USA 98, 2837 2842.
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 2837-2842
-
-
Vila, M.1
Jackson-Lewis, V.2
Vukosavic, S.3
Djaldetti, R.4
Liberatore, G.5
Offen, D.6
Korsmeyer, S.J.7
Przedborski, S.8
-
52
-
-
16244367423
-
Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables
-
Volk H., Potschka H. Loscher W. (2005) Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables. J. Histochem. Cytochem. 53, 517 531.
-
(2005)
J. Histochem. Cytochem.
, vol.53
, pp. 517-531
-
-
Volk, H.1
Potschka, H.2
Loscher, W.3
-
53
-
-
0037113928
-
Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice
-
Wang X., Xu L., Wang H., Young P. R., Gaestel M. Feuerstein G. Z. (2002) Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice. J. Biol. Chem. 277, 43968 43972.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43968-43972
-
-
Wang, X.1
Xu, L.2
Wang, H.3
Young, P.R.4
Gaestel, M.5
Feuerstein, G.Z.6
-
54
-
-
0025327731
-
Unbiased stereological estimation of the number of neurons in the human hippocampus
-
West M. J. Gundersen H. J. (1990) Unbiased stereological estimation of the number of neurons in the human hippocampus. J. Comp. Neurol. 296, 1 22.
-
(1990)
J. Comp. Neurol.
, vol.296
, pp. 1-22
-
-
West, M.J.1
Gundersen, H.J.2
-
55
-
-
0037366093
-
Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: Implications for Parkinson's disease
-
Wilms H., Rosenstiel P., Sievers J., Deuschl G., Zecca L. Lucius R. (2003) Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease. FASEB J. 17, 500 502.
-
(2003)
FASEB J.
, vol.17
, pp. 500-502
-
-
Wilms, H.1
Rosenstiel, P.2
Sievers, J.3
Deuschl, G.4
Zecca, L.5
Lucius, R.6
-
56
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
Wu D. C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D. K., Ischiropoulos H. Przedborski S. (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 22, 1763 1771.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
57
-
-
0035895961
-
P38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons
-
Yamagishi S., Yamada M., Ishikawa Y., Matsumoto T., Ikeuchi T. Hatanaka H. (2001) p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons. J. Biol. Chem. 276, 5129 5133.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5129-5133
-
-
Yamagishi, S.1
Yamada, M.2
Ishikawa, Y.3
Matsumoto, T.4
Ikeuchi, T.5
Hatanaka, H.6
|