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Volumn 3, Issue 4 SUPPL., 2004, Pages

MVA as a vector for vaccines against HIV-1

Author keywords

HIV 1 vaccines; MVA; Prime boost

Indexed keywords

CD4 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEF PROTEIN; VIRUS VECTOR;

EID: 4344714042     PISSN: 14760584     EISSN: None     Source Type: Journal    
DOI: 10.1586/14760584.3.4.S89     Document Type: Review
Times cited : (41)

References (81)
  • 1
    • 0038270791 scopus 로고    scopus 로고
    • Medicine. The need for a global HIV vaccine enterprise
    • Klausner RD, Fauci AS, Corey L et al. Medicine. The need for a global HIV vaccine enterprise. Science 300, 2036-2039 (2003). A paper describing a strategy for global co-ordination of HIV vaccine development.
    • (2003) Science , vol.300 , pp. 2036-2039
    • Klausner, R.D.1    Fauci, A.S.2    Corey, L.3
  • 2
    • 0032577442 scopus 로고    scopus 로고
    • T-cell responses and viral escape
    • McMichael A. T-cell responses and viral escape. Cell 93, 673-676 (1998).
    • (1998) Cell , vol.93 , pp. 673-676
    • McMichael, A.1
  • 3
    • 0037069682 scopus 로고    scopus 로고
    • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
    • Kwong PD, Doyle ML, Casper DJ et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature 420, 678-682 (2002).
    • (2002) Nature , vol.420 , pp. 678-682
    • Kwong, P.D.1    Doyle, M.L.2    Casper, D.J.3
  • 5
    • 0036397709 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte escape monitoring in simian immunodeficiency virus vaccine challenge studies
    • O'Connor DH, Allen TM, Watkins DI. Cytotoxic T-lymphocyte escape monitoring in simian immunodeficiency virus vaccine challenge studies. DNA Cell Biol. 21, 659-664 (2002).
    • (2002) DNA Cell Biol. , vol.21 , pp. 659-664
    • O'Connor, D.H.1    Allen, T.M.2    Watkins, D.I.3
  • 7
    • 0141761519 scopus 로고    scopus 로고
    • Vaccinia vectors as candidate vaccines: The development of modified vaccinia virus Ankara for antigen delivery
    • Sutter G, Staib C. Vaccinia vectors as candidate vaccines: the development of modified vaccinia virus Ankara for antigen delivery. Curr. Drug Targets Infect. Disord. 3, 263-271 (2003).
    • (2003) Curr. Drug Targets Infect. Disord. , vol.3 , pp. 263-271
    • Sutter, G.1    Staib, C.2
  • 8
    • 0016721708 scopus 로고
    • Abstammung, eigenschaften und verwendung des attenuierten vaccinia-stammes MVA
    • Mayr A, Hochstein-Mintzel V, Stickl H. Abstammung, Eigenschaften und Verwendung des attenuierten Vaccinia-Stammes MVA. Infection 105, 6-14 (1975).
    • (1975) Infection , vol.105 , pp. 6-14
    • Mayr, A.1    Hochstein-Mintzel, V.2    Stickl, H.3
  • 11
    • 0018246525 scopus 로고
    • Der pockenimpfstamm MVA marker genetische struktur, erfahrungen mit der parenteralen schutzimpfung und verhalten im. abwehrgeschwachten organismus
    • Mayr A, Stickl H, Muller HK, Danner K, Singer H. Der Pockenimpfstamm MVA: Marker, genetische Struktur, Erfahrungen mit der parenteralen Schutzimpfung und Verhalten im. abwehrgeschwachten Organismus. Zentralbl. Bakt. Hyg. I. (Abt. Orig. B) 167, 375-390 (1978).
    • (1978) Zentralbl. Bakt. Hyg. I. (Abt. Orig. B) , vol.167 , pp. 375-390
    • Mayr, A.1    Stickl, H.2    Muller, H.K.3    Danner, K.4    Singer, H.5
  • 12
    • 0011880157 scopus 로고
    • Vaccinia virus: A selectable eukaryotic cloning and expression vector
    • Mackett M, Smith GL, Moss B. Vaccinia virus: a selectable eukaryotic cloning and expression vector. Proc. Natl Acad. Sci. USA 79, 7415-7419 (1982). Demonstration that vaccinia viruses can be used as vectors, which can carry and express foreign genes.
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , pp. 7415-7419
    • Mackett, M.1    Smith, G.L.2    Moss, B.3
  • 13
    • 0025876805 scopus 로고
    • Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence
    • Meyer H, Sutter G, Mayr A. Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence. J. Gen. Virol. 72, 1031-1038 (1991).
    • (1991) J. Gen. Virol. , vol.72 , pp. 1031-1038
    • Meyer, H.1    Sutter, G.2    Mayr, A.3
  • 14
    • 0032503233 scopus 로고    scopus 로고
    • The complete genomic sequence of the modified vaccinia Ankara strain: Comparison with other orthopoxviruses
    • Antoine G, Scheiflinger F, Dorner F, Falkner FG. The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses. Virology 244, 365-396 (1998).
    • (1998) Virology , vol.244 , pp. 365-396
    • Antoine, G.1    Scheiflinger, F.2    Dorner, F.3    Falkner, F.G.4
  • 15
    • 0026442276 scopus 로고
    • Nonreplicating vaccinia vector efficiently expresses recombinant genes
    • Sutter G, Moss B. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc. Natl Acad Sci. USA 89, 10847-10851 (1992).
    • (1992) Proc. Natl Acad Sci. USA , vol.89 , pp. 10847-10851
    • Sutter, G.1    Moss, B.2
  • 16
    • 0031899907 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: Implications for use as a human vaccine
    • Blanchard TJ, Alcami A, Andrea P, Smith GL. Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine. J. Gen. Virol. 79, 1159-1167 (1998).
    • (1998) J. Gen. Virol. , vol.79 , pp. 1159-1167
    • Blanchard, T.J.1    Alcami, A.2    Andrea, P.3    Smith, G.L.4
  • 17
    • 0029176287 scopus 로고
    • Novel vaccinia vector derived from the host range restricted and highly attenuated MVA strain of vaccinia virus
    • Sutter G, Moss B. Novel vaccinia vector derived from the host range restricted and highly attenuated MVA strain of vaccinia virus. Dev. Biol. Stand. 84, 195-200 (1995). Paper pioneering the use of MVA as a vector for passenger genes.
    • (1995) Dev. Biol. Stand. , vol.84 , pp. 195-200
    • Sutter, G.1    Moss, B.2
  • 18
    • 0028285633 scopus 로고
    • Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant
    • Sutter G, Ramsey EA, Rosales R, Moss B. Stable expression of the vaccinia virus K1L gene in rabbit cells complements the host range defect of a vaccinia virus mutant. J. Virol. 68, 4109-4116 (1994). Paper pioneering the use of MVA as a vector for passenger genes.
    • (1994) J. Virol. , vol.68 , pp. 4109-4116
    • Sutter, G.1    Ramsey, E.A.2    Rosales, R.3    Moss, B.4
  • 19
    • 9044232149 scopus 로고    scopus 로고
    • Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates
    • Moss B, Carroll MW, Wyatt LS et al. Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates. Adv. Exp. Med. Biol. 397, 7-13 (1996).
    • (1996) Adv. Exp. Med. Biol. , vol.397 , pp. 7-13
    • Moss, B.1    Carroll, M.W.2    Wyatt, L.S.3
  • 20
    • 0029940996 scopus 로고    scopus 로고
    • Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: Effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara
    • Hirsch VM, Fuerst TR, Sutter G et al. Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: Effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara. J. Virol. 70, 3741-3752 (1996). The first use of rMVAs as vaccines in nonhuman primates.
    • (1996) J. Virol. , vol.70 , pp. 3741-3752
    • Hirsch, V.M.1    Fuerst, T.R.2    Sutter, G.3
  • 21
    • 15144345621 scopus 로고    scopus 로고
    • Immunogenicities of iv. and im. administrations of MVA-based multi-CTL epitope vaccine for HIV in mice
    • Hanke T, Blanchard TJ, Schneider J et al. Immunogenicities of iv. and im. administrations of MVA-based multi-CTL epitope vaccine for HIV in mice. J. Gen. Virol. 79, 83-90 (1998).
    • (1998) J. Gen. Virol. , vol.79 , pp. 83-90
    • Hanke, T.1    Blanchard, T.J.2    Schneider, J.3
  • 22
    • 0242384126 scopus 로고    scopus 로고
    • Therapeutic vaccination with MVA-HIV-1 nef elicits Nef-specific T-helper cell responses in chronically HIV-1 infected individuals
    • Cosma A, Nagaraj R, Buhler S et al. Therapeutic vaccination with MVA-HIV-1 nef elicits Nef-specific T-helper cell responses in chronically HIV-1 infected individuals. Vaccine 22, 21-29 (2003). The first trial report of rMVA as a therapeutic HIV vaccine in HIV-infected humans on antiretroviral drugs.
    • (2003) Vaccine , vol.22 , pp. 21-29
    • Cosma, A.1    Nagaraj, R.2    Buhler, S.3
  • 23
    • 11144355460 scopus 로고    scopus 로고
    • An HIV-1 clade A vaccine in clinical trials: Stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans
    • Mwau M Cebere I, Sutton J et al. An HIV-1 clade A vaccine in clinical trials: Stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. J. Gen. Virol. 85, 911-919 (2004). The first human trial report on a HIV vaccine using rMVA alone and in a prime-boost regimen.
    • (2004) J. Gen. Virol. , vol.85 , pp. 911-919
    • Mwau, M.1    Cebere, I.2    Sutton, J.3
  • 24
    • 0038714287 scopus 로고    scopus 로고
    • Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
    • McConkey SJ, Reece WH, Moorthy VS. et al. Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans. Nature Med. 9, 729-735 (2003). The first use of rMVA in a prime-boost regimen in humans.
    • (2003) Nature Med. , vol.9 , pp. 729-735
    • McConkey, S.J.1    Reece, W.H.2    Moorthy, V.S.3
  • 25
    • 0742324611 scopus 로고    scopus 로고
    • Phase I immunotherapy with a modified vaccinia virus (MVA) expressing human MUC1 as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer
    • Rochlitz C, Figlin R, Squiban P et al. Phase I immunotherapy with a modified vaccinia virus (MVA) expressing human MUC1 as antigen-specific immunotherapy in patients with MUC1-positive advanced cancer. J. Gene Med. 5, 690-699 (2003).
    • (2003) J. Gene Med. , vol.5 , pp. 690-699
    • Rochlitz, C.1    Figlin, R.2    Squiban, P.3
  • 26
    • 0031585552 scopus 로고    scopus 로고
    • Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: Propagation and generation of recombinant viruses in a nonhuman mammalian cell line
    • Carroll MW, Moss B. Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line. Virology 238, 198-211 (1997).
    • (1997) Virology , vol.238 , pp. 198-211
    • Carroll, M.W.1    Moss, B.2
  • 27
    • 0031974691 scopus 로고    scopus 로고
    • Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation but not in various human transformed and primary cells
    • Drexler I, Heller K, Wahren B, Erfle V, Sutter G. Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation but not in various human transformed and primary cells. J. Gen. Virol. 79, 347-352 (1998).
    • (1998) J. Gen. Virol. , vol.79 , pp. 347-352
    • Drexler, I.1    Heller, K.2    Wahren, B.3    Erfle, V.4    Sutter, G.5
  • 28
    • 0342470981 scopus 로고    scopus 로고
    • Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: Virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine
    • Ramirez JC, Gherardi MM, Esteban M. Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine. J. Virol. 74, 923-933 (2000).
    • (2000) J. Virol. , vol.74 , pp. 923-933
    • Ramirez, J.C.1    Gherardi, M.M.2    Esteban, M.3
  • 29
    • 0037159648 scopus 로고    scopus 로고
    • Lack of toxicity and persistence in the mouse associated with administration of candidate DNA- and modified vaccinia virus Ankara (MVA)-based HIV vaccines for Kenya
    • Hanke T, McMchael AJ, Samuel RS et al. Lack of toxicity and persistence in the mouse associated with administration of candidate DNA- and modified vaccinia virus Ankara (MVA)-based HIV vaccines for Kenya. Vaccine 21, 109-115 (2002).
    • (2002) Vaccine , vol.21 , pp. 109-115
    • Hanke, T.1    McMchael, A.J.2    Samuel, R.S.3
  • 30
    • 0037547065 scopus 로고    scopus 로고
    • Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration
    • Ramirez JC, Finke D, Esteban M, Kraehenbuhl JP, Acha-Orbea H. Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration. Arch. Virol. 148, 827-839 (2003).
    • (2003) Arch. Virol. , vol.148 , pp. 827-839
    • Ramirez, J.C.1    Finke, D.2    Esteban, M.3    Kraehenbuhl, J.P.4    Acha-Orbea, H.5
  • 31
    • 0019152303 scopus 로고
    • Studies on poxvirus infections in irradiated animals
    • Werner GT, Jentzsch U, Metzger E, Simon J. Studies on poxvirus infections in irradiated animals. Arch. Virol. 64, 247-256 (1980).
    • (1980) Arch. Virol. , vol.64 , pp. 247-256
    • Werner, G.T.1    Jentzsch, U.2    Metzger, E.3    Simon, J.4
  • 32
    • 12844283368 scopus 로고    scopus 로고
    • Safety, biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice
    • Submitted
    • Hanke T, McMichael AJ, Dennis MJ, Powell LAJ, McLoughlin L, Crome SJ. Safety, biodistribution and persistence of an MVA-vectored candidate HIV vaccine in SIV-infected rhesus macaques and SCID mice. Vaccine (Submitted).
    • Vaccine
    • Hanke, T.1    McMichael, A.J.2    Dennis, M.J.3    Powell, L.A.J.4    McLoughlin, L.5    Crome, S.J.6
  • 33
    • 0037178303 scopus 로고    scopus 로고
    • Comparison of the efficacy of early versus late viral proteins in vaccination against SIV
    • Stittelaar KJ, Gruters RA, Schutten M et al. Comparison of the efficacy of early versus late viral proteins in vaccination against SIV. Vaccine 20, 2921-2927 (2002).
    • (2002) Vaccine , vol.20 , pp. 2921-2927
    • Stittelaar, K.J.1    Gruters, R.A.2    Schutten, M.3
  • 34
    • 0037449091 scopus 로고    scopus 로고
    • Safety of DNA and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers
    • Moorthy VS, McConkey S, Roberts M et al. Safety of DNA and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers. Vaccine 21, 2004-2011 (2003).
    • (2003) Vaccine , vol.21 , pp. 2004-2011
    • Moorthy, V.S.1    McConkey, S.2    Roberts, M.3
  • 35
    • 0242364645 scopus 로고    scopus 로고
    • Safety and immunogenicity of DNA/modified vaccinia virus Ankara malaria vaccination in African adults
    • Moorthy VS, Pinder M, Reece WH et al. Safety and immunogenicity of DNA/modified vaccinia virus Ankara malaria vaccination in African adults. J. Infect. Dis. 188, 1239-1244 (2003).
    • (2003) J. Infect. Dis. , vol.188 , pp. 1239-1244
    • Moorthy, V.S.1    Pinder, M.2    Reece, W.H.3
  • 36
    • 0038447170 scopus 로고    scopus 로고
    • Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L
    • Homemann S, Harlin O, Staib C et al. Replication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L. J. Virol. 77, 8394-8407 (2003).
    • (2003) J. Virol. , vol.77 , pp. 8394-8407
    • Homemann, S.1    Harlin, O.2    Staib, C.3
  • 37
    • 0036319711 scopus 로고    scopus 로고
    • Molecular epidemiology of HIV-1 genetic forms and its significance for vaccine development and therapy
    • Thomson MM, Perez-Alvarez L, Najera R. Molecular epidemiology of HIV-1 genetic forms and its significance for vaccine development and therapy. Lancet Infect. Dis. 2, 461-471 (2002).
    • (2002) Lancet Infect. Dis. , vol.2 , pp. 461-471
    • Thomson, M.M.1    Perez-Alvarez, L.2    Najera, R.3
  • 38
    • 0030846020 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus Type 1 clades: Implications for vaccine development
    • Cao H, Kanki P, Sankale JL et al. Cytotoxic T-lymphocyte cross-reactivity among different human immunodeficiency virus Type 1 clades: implications for vaccine development. J. Virol. 71, 8615-8623 (1997).
    • (1997) J. Virol. , vol.71 , pp. 8615-8623
    • Cao, H.1    Kanki, P.2    Sankale, J.L.3
  • 39
    • 0030829060 scopus 로고    scopus 로고
    • Replication-defective canarypox (ALVAC) vectors effectively activate antihuman immunodeficiency virus-1 cytotoxic T-lymphocytes present in infected patients: Implications for antigen-specific immunotherapy
    • Ferrari G, Berend C, Ottinger J et al. Replication-defective canarypox (ALVAC) vectors effectively activate antihuman immunodeficiency virus-1 cytotoxic T-lymphocytes present in infected patients: implications for antigen-specific immunotherapy. Blood 90, 2406-2416 (1997).
    • (1997) Blood , vol.90 , pp. 2406-2416
    • Ferrari, G.1    Berend, C.2    Ottinger, J.3
  • 40
    • 0035377540 scopus 로고    scopus 로고
    • Immune control of HIV: The obstacles of HLA and viral diversity
    • Walker BD, Korber BT. Immune control of HIV: the obstacles of HLA and viral diversity. Nature Immunol. 2, 473-475. (2001).
    • (2001) Nature Immunol. , vol.2 , pp. 473-475
    • Walker, B.D.1    Korber, B.T.2
  • 42
    • 0036547156 scopus 로고    scopus 로고
    • The quest for an AIDS vaccine: Is the CD8+ T-cell approach feasible?
    • McMichael AJ, Hanke T. The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible? Nature Rev. Immunol. 2, 283-291 (2002).
    • (2002) Nature Rev. Immunol. , vol.2 , pp. 283-291
    • McMichael, A.J.1    Hanke, T.2
  • 43
    • 0033046472 scopus 로고    scopus 로고
    • Immunodominance in major histocompatibility complex class I-restricted T-lymphocyte responses
    • Yewdell JW, Bennink JR. Immunodominance in major histocompatibility complex class I-restricted T-lymphocyte responses. Ann. Rev. Immunol. 17, 51-88 (1999).
    • (1999) Ann. Rev. Immunol. , vol.17 , pp. 51-88
    • Yewdell, J.W.1    Bennink, J.R.2
  • 44
    • 10744230389 scopus 로고    scopus 로고
    • Development of a DNA vaccine designed to induce cytotoxic T-lymphocyte responses to Multiple conserved epitopes in HIV-1
    • Wilson CC, McKinney D, Anders M et al. Development of a DNA vaccine designed to induce cytotoxic T-lymphocyte responses to Multiple conserved epitopes in HIV-1. J. Immunol. 171, 5611-5623 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 5611-5623
    • Wilson, C.C.1    McKinney, D.2    Anders, M.3
  • 45
    • 0032543212 scopus 로고    scopus 로고
    • Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T-cell responses to naturally processed peptides
    • Gallimore A, Dumrese T, Hengartner H, Zinkernagel RM, Rammensee HG. Protective immunity does not correlate with the hierarchy of virus-specific cytotoxic T-cell responses to naturally processed peptides. J. Exp. Med. 187, 1647-1657 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1647-1657
    • Gallimore, A.1    Dumrese, T.2    Hengartner, H.3    Zinkernagel, R.M.4    Rammensee, H.G.5
  • 47
    • 3242793450 scopus 로고    scopus 로고
    • Engineering RENTA, a DNA prime-MVA boost HIV vaccine tailored for Eastern and Central Africa
    • In Press
    • Nkolola JP, Wee EG-T, Im E-J et al. Engineering RENTA, a DNA prime-MVA boost HIV vaccine tailored for Eastern and Central Africa. Gene Ther. (In Press) (2004).
    • (2004) Gene Ther.
    • Nkolola, J.P.1    Wee, E.G.-T.2    Im, E.-J.3
  • 48
    • 0025765276 scopus 로고
    • Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus
    • Gotch FM, Hovell R, Delchambre M, Silvera P, McMichael AJ. Cytotoxic T-cell response to simian immunodeficiency virus by cynomolgus macaque monkeys immunized with recombinant vaccinia virus. AIDS 5, 317-320 (1991).
    • (1991) AIDS , vol.5 , pp. 317-320
    • Gotch, F.M.1    Hovell, R.2    Delchambre, M.3    Silvera, P.4    McMichael, A.J.5
  • 49
    • 0035690939 scopus 로고    scopus 로고
    • Virus infections: Escape, resistance and counterattack
    • Xu XN, Screaton GR, McMichael AJ. Virus infections: escape, resistance and counterattack. Immunity 15, 867-870 (2001).
    • (2001) Immunity , vol.15 , pp. 867-870
    • Xu, X.N.1    Screaton, G.R.2    McMichael, A.J.3
  • 51
    • 0141796316 scopus 로고    scopus 로고
    • Duration of antiviral immunity after smallpox vaccination
    • Hammarlund E, Lewis MW, Hansen SG et al. Duration of antiviral immunity after smallpox vaccination. Nature Med. 9, 1131-1137 (2003). Dectection of vaccina virus-specific memory T-cells in individuals vaccinated against smallpox many years ago.
    • (2003) Nature Med. , vol.9 , pp. 1131-1137
    • Hammarlund, E.1    Lewis, M.W.2    Hansen, S.G.3
  • 52
    • 0242495755 scopus 로고    scopus 로고
    • Cutting edge: Long-term B-cell memory in humans after smallpox vaccination
    • Crotty S, Felgner P, Davies H, Glidewell J, Villarreal L, Ahmed R. Cutting edge: long-term B-cell memory in humans after smallpox vaccination. J. Immunol. 171, 4969-4973 (2003). Dectection of vaccinia virus-specific memory T-cells in individuals vaccinated against smallpox many years ago.
    • (2003) J. Immunol. , vol.171 , pp. 4969-4973
    • Crotty, S.1    Felgner, P.2    Davies, H.3    Glidewell, J.4    Villarreal, L.5    Ahmed, R.6
  • 53
    • 0037422549 scopus 로고    scopus 로고
    • Identification of vaccinia virus epitope-specific HLA-A*0201- restricted T-cells and comparative analysis of smallpox vaccines
    • Drexler I, Staib C, Kastenmuller W et al. Identification of vaccinia virus epitope-specific HLA-A*0201-restricted T-cells and comparative analysis of smallpox vaccines. Proc. Natl Acad. Sci. USA 100, 217-222 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 217-222
    • Drexler, I.1    Staib, C.2    Kastenmuller, W.3
  • 54
    • 0034088113 scopus 로고    scopus 로고
    • Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge
    • Seth A, Ourmanov I, Schmitz JE et al. Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge. J. Virol. 74, 2502-2509 (2000).
    • (2000) J. Virol. , vol.74 , pp. 2502-2509
    • Seth, A.1    Ourmanov, I.2    Schmitz, J.E.3
  • 55
    • 0027973079 scopus 로고
    • The relationship between class I binding affinity and immunogenicity of potential cytotoxic T-cell epitopes
    • Sette A, Vitiello A, Reherman B et al. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T-cell epitopes. J. Immunol. 153, 5586-5592 (1995).
    • (1995) J. Immunol. , vol.153 , pp. 5586-5592
    • Sette, A.1    Vitiello, A.2    Reherman, B.3
  • 56
    • 0033547972 scopus 로고    scopus 로고
    • Effective induction of HIV-specific CTL by multi-epitope DNA using a gene gun in a combined vaccination regime
    • Hanke T, Neumann VC, Blanchard TJ et al. Effective induction of HIV-specific CTL by multi-epitope DNA using a gene gun in a combined vaccination regime. Vaccine 17, 589-596 (1999).
    • (1999) Vaccine , vol.17 , pp. 589-596
    • Hanke, T.1    Neumann, V.C.2    Blanchard, T.J.3
  • 57
    • 0033995525 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus ankara expressing the surface gp120 of simian immunodeficiency virus (SIV) primes for a rapid neutralizing antibody response to SIV infection in macaques
    • Ourmanov I, Bilska M, Hirsch VM, Montefiori DC. Recombinant modified vaccinia virus ankara expressing the surface gp120 of simian immunodeficiency virus (SIV) primes for a rapid neutralizing antibody response to SIV infection in macaques. J. Virol. 74, 2960-2965 (2000).
    • (2000) J. Virol. , vol.74 , pp. 2960-2965
    • Ourmanov, I.1    Bilska, M.2    Hirsch, V.M.3    Montefiori, D.C.4
  • 58
    • 0034093217 scopus 로고    scopus 로고
    • Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV
    • Ourmanov I, Brown CR, Moss B et al. Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV. J. Virol. 74, 2740-2751 (2000).
    • (2000) J. Virol. , vol.74 , pp. 2740-2751
    • Ourmanov, I.1    Brown, C.R.2    Moss, B.3
  • 59
    • 0034857126 scopus 로고    scopus 로고
    • Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: Influence of pre-existing antivector immunity
    • Sharpe S, Polyanskaya N, Dennis M et al. Induction of simian immunodeficiency virus (SIV)-specific CTL in rhesus macaques by vaccination with modified vaccinia virus Ankara expressing SIV transgenes: influence of pre-existing antivector immunity. J. Gen. Virol. 82, 2215-2223 (2001).
    • (2001) J. Gen. Virol. , vol.82 , pp. 2215-2223
    • Sharpe, S.1    Polyanskaya, N.2    Dennis, M.3
  • 60
    • 0028074787 scopus 로고
    • A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus
    • Sutter G, Wyatt LS, Foley PL, Bennink JR, Moss B. A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus. Vaccine 12, 1032-1040 (1994).
    • (1994) Vaccine , vol.12 , pp. 1032-1040
    • Sutter, G.1    Wyatt, L.S.2    Foley, P.L.3    Bennink, J.R.4    Moss, B.5
  • 61
    • 0029836437 scopus 로고    scopus 로고
    • Oral immunization with a replication-deficient recombinant vaccinia virus protects mice against influenza
    • Bender BS, Rowe CA, Taylor SF, Wyatt LS, Moss B, Small PAJ. Oral immunization with a replication-deficient recombinant vaccinia virus protects mice against influenza. J. Virol. 70, 6418-6424 (1996).
    • (1996) J. Virol. , vol.70 , pp. 6418-6424
    • Bender, B.S.1    Rowe, C.A.2    Taylor, S.F.3    Wyatt, L.S.4    Moss, B.5    Small, P.A.J.6
  • 62
    • 0032145732 scopus 로고    scopus 로고
    • The immunogenicity and efficacy of intranasally or parenterally administered replication-deficient vaccinia-parainfluenza virus Type 3 recombinants in rhesus monkeys
    • Durbin AP, Wyatt LS, Siew J, Moss B, Murphy BR. The immunogenicity and efficacy of intranasally or parenterally administered replication-deficient vaccinia-parainfluenza virus Type 3 recombinants in rhesus monkeys. Vaccine 16, 1324-1330 (1998).
    • (1998) Vaccine , vol.16 , pp. 1324-1330
    • Durbin, A.P.1    Wyatt, L.S.2    Siew, J.3    Moss, B.4    Murphy, B.R.5
  • 63
    • 0031660670 scopus 로고    scopus 로고
    • Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein
    • Belyakov IM, Wyatt LS, Ahlers JD et al. Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein. J. Virol. 71, 8264-8272 (1998).
    • (1998) J. Virol. , vol.71 , pp. 8264-8272
    • Belyakov, I.M.1    Wyatt, L.S.2    Ahlers, J.D.3
  • 64
    • 0033551132 scopus 로고    scopus 로고
    • Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by pre-existing poxvirus immunity
    • Belyakov IM, Moss B, Strober W, Berzofsky JA. Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by pre-existing poxvirus immunity. Proc. Natl Acad. Sci. USA 96, 4512-4517 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.96 , pp. 4512-4517
    • Belyakov, I.M.1    Moss, B.2    Strober, W.3    Berzofsky, J.A.4
  • 65
    • 0034766337 scopus 로고    scopus 로고
    • Transduction of human dendritic cells with a recombinant modified vaccinia Ankara virus encoding MUC1 and IL-2
    • Trevor KT, Hersh EM, Brailey J, Balloul JM, Acres B. Transduction of human dendritic cells with a recombinant modified vaccinia Ankara virus encoding MUC1 and IL-2. Cancer Immunol. Immunother. 50, 397-407 (2001).
    • (2001) Cancer Immunol. Immunother. , vol.50 , pp. 397-407
    • Trevor, K.T.1    Hersh, E.M.2    Brailey, J.3    Balloul, J.M.4    Acres, B.5
  • 66
    • 0033571120 scopus 로고    scopus 로고
    • A triad of costimulatory molecules synergize to amplify T-cell activation
    • Hodge JW, Sabzevari H, Yafal AG, Gritz L, Lorenz MG, Schlom J. A triad of costimulatory molecules synergize to amplify T-cell activation. Cancer Res. 59, 5800-5807 (1999). Synergistic enhancement of MVA immunogenicity by coinsertion of costimulatory and adhesion surface molecules.
    • (1999) Cancer Res. , vol.59 , pp. 5800-5807
    • Hodge, J.W.1    Sabzevari, H.2    Yafal, A.G.3    Gritz, L.4    Lorenz, M.G.5    Schlom, J.6
  • 67
    • 85047699277 scopus 로고    scopus 로고
    • Tumor gene therapy by MVA-mediated expression of T-cell-stimulating antibodies
    • Paul S, Regulier E, Rooke R et al. Tumor gene therapy by MVA-mediated expression of T-cell-stimulating antibodies. Cancer Gene Ther. 9, 470-477 (2002).
    • (2002) Cancer Gene Ther. , vol.9 , pp. 470-477
    • Paul, S.1    Regulier, E.2    Rooke, R.3
  • 68
    • 0032033577 scopus 로고    scopus 로고
    • Enhancement of MHC class I-restricted peptide-specific T-cell induction by a DNA prime/MVA boost vaccination regime
    • Hanke T, Blanchard TJ, Schneider J et al. Enhancement of MHC class I-restricted peptide-specific T-cell induction by a DNA prime/MVA boost vaccination regime. Vaccine 16, 439-445 (1998). The first demonstration of effective induction of CTLs by DNA prime-MVA boost regimen.
    • (1998) Vaccine , vol.16 , pp. 439-445
    • Hanke, T.1    Blanchard, T.J.2    Schneider, J.3
  • 69
    • 0031924077 scopus 로고    scopus 로고
    • + T-cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara
    • + T-cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nature Med. 4, 397-402 (1998). The first demonstration of effective induction of protective T-cell responses by DNA prime-MVA boost regimen, which were superior to those induced by each vector alone.
    • (1998) Nature Med. , vol.4 , pp. 397-402
    • Schneider, J.1    Gilbert, S.C.2    Blanchard, T.J.3
  • 70
    • 0032815843 scopus 로고    scopus 로고
    • Effective induction of simian immunodeficiency virus-specific cytotoxic T-lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen
    • Hanke T, Samuel RV, Blanchard TJ et al. Effective induction of simian immunodeficiency virus-specific cytotoxic T-lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen. J. Virol. 73, 7524-7532 (1999). The first demonstration of effective induction of CTLs by DNA prime-MVA boost regimen in nonhuman primates.
    • (1999) J. Virol. , vol.73 , pp. 7524-7532
    • Hanke, T.1    Samuel, R.V.2    Blanchard, T.J.3
  • 71
    • 18144441678 scopus 로고    scopus 로고
    • Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen
    • Allen TM, Vogel TU, Fuller DH et al. Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen. J. Immunol. 164, 4968-4978 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 4968-4978
    • Allen, T.M.1    Vogel, T.U.2    Fuller, D.H.3
  • 72
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multi-protein DNA/MVA vaccine
    • Amara RR, Villinger F, Altman JD et al. Control of a mucosal challenge and prevention of AIDS by a multi-protein DNA/MVA vaccine. Science 292, 69-74 (2001). Demonstration of a partial protective efficacy of DNA prime-MVA boost protocol against SHIV challenge in macaques.
    • (2001) Science , vol.292 , pp. 69-74
    • Amara, R.R.1    Villinger, F.2    Altman, J.D.3
  • 73
    • 0037122719 scopus 로고    scopus 로고
    • Replication-incompetent adenoviral vaccine vector elicits effective antiimmunodeficiency-virus immunity
    • Shiver JW, Fu TM, Chen L et al. Replication-incompetent adenoviral vaccine vector elicits effective antiimmunodeficiency-virus immunity. Nature 415, 331-335 (2002).
    • (2002) Nature , vol.415 , pp. 331-335
    • Shiver, J.W.1    Fu, T.M.2    Chen, L.3
  • 74
    • 0037081381 scopus 로고    scopus 로고
    • Enhanced CD8 T-cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes
    • Gilbert SC, Schneider J, Hannan CM et al. Enhanced CD8 T-cell immunogenicity and protective efficacy in a mouse malaria model using a recombinant adenoviral vaccine in heterologous prime-boost immunisation regimes. Vaccine 20, 1039-1045 (2002).
    • (2002) Vaccine , vol.20 , pp. 1039-1045
    • Gilbert, S.C.1    Schneider, J.2    Hannan, C.M.3
  • 76
    • 0347088996 scopus 로고    scopus 로고
    • A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses
    • Prieur E, Gilbert SC, Schneider J et al. A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses. Proc. Natl Acad. Sci. USA 101, 290-295 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 290-295
    • Prieur, E.1    Gilbert, S.C.2    Schneider, J.3
  • 77
    • 0037311644 scopus 로고    scopus 로고
    • Construction and immunogenicity in a prime-boost regimen of a Semliki Forest virus-vectored experimental HIV clade A vaccine
    • Hanke T, Barnfield C, Wee EG-T et al. Construction and immunogenicity in a prime-boost regimen of a Semliki Forest virus-vectored experimental HIV clade A vaccine. J. Gen. Virol. 84, 361-368 (2003).
    • (2003) J. Gen. Virol. , vol.84 , pp. 361-368
    • Hanke, T.1    Barnfield, C.2    Wee, E.G.-T.3
  • 78
    • 0035858105 scopus 로고    scopus 로고
    • Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara
    • Nilsson C, Makitalo B, Berglund P et al. Enhanced simian immunodeficiency virus-specific immune responses in macaques induced by priming with recombinant Semliki Forest virus and boosting with modified vaccinia virus Ankara. Vaccine 19, 3526-3536 (2001).
    • (2001) Vaccine , vol.19 , pp. 3526-3536
    • Nilsson, C.1    Makitalo, B.2    Berglund, P.3
  • 79
    • 0038279752 scopus 로고    scopus 로고
    • Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes
    • Gherardi MM, Najera JL, Perez-Jimenez E, Guerra S, Garcia-Sastre A, Esteban M. Prime-boost immunization schedules based on influenza virus and vaccinia virus vectors potentiate cellular immune responses against human immunodeficiency virus Env protein systemically and in the genitorectal draining lymph nodes. J. Virol. 77, 7048-7057 (2003).
    • (2003) J. Virol. , vol.77 , pp. 7048-7057
    • Gherardi, M.M.1    Najera, J.L.2    Perez-Jimenez, E.3    Guerra, S.4    Garcia-Sastre, A.5    Esteban, M.6
  • 80
    • 0033826855 scopus 로고    scopus 로고
    • Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya
    • Hanke T, McMichael AJ. Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya. Nature Med. 6, 951-955 (2000).
    • (2000) Nature Med. , vol.6 , pp. 951-955
    • Hanke, T.1    McMichael, A.J.2
  • 81
    • 0036109159 scopus 로고    scopus 로고
    • Memory CD8+ T-cells vary in differentiation phenotype in different persistent virus infections
    • Appay V, Dunbar PR, Callan M et al. Memory CD8+ T-cells vary in differentiation phenotype in different persistent virus infections. Nature Med. 8, 379-385 (2002).
    • (2002) Nature Med. , vol.8 , pp. 379-385
    • Appay, V.1    Dunbar, P.R.2    Callan, M.3


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