메뉴 건너뛰기




Volumn 74, Issue 2, 2000, Pages 923-933

Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: Virus fate and activation of B- and T-cell immune responses in comparison with the western reserve strain and advantages as a vaccine

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 6; LUCIFERASE; TUMOR NECROSIS FACTOR ALPHA; VACCINIA VACCINE; VIRUS ANTIGEN; VIRUS VECTOR;

EID: 0342470981     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.2.923-933.2000     Document Type: Article
Times cited : (199)

References (59)
  • 1
    • 0024601044 scopus 로고
    • Partial deletion of the human host range in the attenuated vaccinia virus MVA
    • Altenburger, W., C.-P. Süter, and J. Altenburger. 1989. Partial deletion of the human host range in the attenuated vaccinia virus MVA. Arch. Virol. 105:15-27.
    • (1989) Arch. Virol. , vol.105 , pp. 15-27
    • Altenburger, W.1    Süter, C.-P.2    Altenburger, J.3
  • 2
    • 0032503233 scopus 로고    scopus 로고
    • The complete genomic sequence of the modified vaccinia Ankara strain: Comparison with other Orthopoxviruses
    • Antoine, G., F. Scheiflinger, F. Dorner, and F. G. Falkner. 1998. The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other Orthopoxviruses. Virology 244:365-396.
    • (1998) Virology , vol.244 , pp. 365-396
    • Antoine, G.1    Scheiflinger, F.2    Dorner, F.3    Falkner, F.G.4
  • 3
    • 0029936947 scopus 로고    scopus 로고
    • Induction of long-lived germinal centers associated with persisting antigen after viral infection
    • Bachmann, M. F., B. Odermatt, H. Hengartner, and R. M. Zinkernagel. 1996. Induction of long-lived germinal centers associated with persisting antigen after viral infection. J. Exp. Med. 183:2259-2269.
    • (1996) J. Exp. Med. , vol.183 , pp. 2259-2269
    • Bachmann, M.F.1    Odermatt, B.2    Hengartner, H.3    Zinkernagel, R.M.4
  • 4
    • 0031035465 scopus 로고    scopus 로고
    • Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?
    • Bachmann, M. F., T. M. Kündig, H. Hengartner, and R. M. Zinkernagel. 1997. Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"? Proc. Natl. Acad. Sci. USA 94:640-645.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 640-645
    • Bachmann, M.F.1    Kündig, T.M.2    Hengartner, H.3    Zinkernagel, R.M.4
  • 5
    • 0031660670 scopus 로고    scopus 로고
    • Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein
    • Belyakov, I. M., L. S. Wyatt, J. D. Ahlers, P. Earl, C. D. Pendleton, B. L. Kelsall, W. Strober, B. Moss, and J. A. Berzofsky. 1998. Induction of a mucosal cytotoxic T-lymphocyte response by intrarectal immunization with a replication-deficient recombinant vaccinia virus expressing human immunodeficiency virus 89.6 envelope protein. J. Virol. 72:8264-8272.
    • (1998) J. Virol. , vol.72 , pp. 8264-8272
    • Belyakov, I.M.1    Wyatt, L.S.2    Ahlers, J.D.3    Earl, P.4    Pendleton, C.D.5    Kelsall, B.L.6    Strober, W.7    Moss, B.8    Berzofsky, J.A.9
  • 6
    • 0033551132 scopus 로고    scopus 로고
    • Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity
    • Belyakov, I. M., B. Moss, W. Strober, and J. A. Berzofsky. 1999. Mucosal vaccination overcomes the barrier to recombinant vaccinia immunization caused by preexisting poxvirus immunity. Proc. Natl. Acad. Sci. USA 96: 4512-4517.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4512-4517
    • Belyakov, I.M.1    Moss, B.2    Strober, W.3    Berzofsky, J.A.4
  • 7
    • 0029836437 scopus 로고    scopus 로고
    • Oral immunization with a replication-deficient recombinant vaccinia virus protects mice against influenza
    • Bender, B. S., C. A. Rowe, S. F. Taylor, L. S. Wyatt, B. Moss, and P. A. Small, Jr. 1996. Oral immunization with a replication-deficient recombinant vaccinia virus protects mice against influenza. J. Virol. 70:6418-6424.
    • (1996) J. Virol. , vol.70 , pp. 6418-6424
    • Bender, B.S.1    Rowe, C.A.2    Taylor, S.F.3    Wyatt, L.S.4    Moss, B.5    Small P.A., Jr.6
  • 8
    • 0031899907 scopus 로고    scopus 로고
    • Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: Implications for use as a human vaccine
    • Blanchard, T. J., A. Alcamí, P. Andrea, and G. L. Smith. 1998. Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine. J. Gen. Virol. 79:1159-1167.
    • (1998) J. Gen. Virol. , vol.79 , pp. 1159-1167
    • Blanchard, T.J.1    Alcamí, A.2    Andrea, P.3    Smith, G.L.4
  • 9
    • 0028979466 scopus 로고
    • New perspectives of CD28-B7-mediated T cell co-stimulation
    • Bluestone, J. A. 1995. New perspectives of CD28-B7-mediated T cell co-stimulation. Immunity 2:555-559.
    • (1995) Immunity , vol.2 , pp. 555-559
    • Bluestone, J.A.1
  • 11
    • 0031004055 scopus 로고    scopus 로고
    • Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: A murine tumor model
    • Carroll, M. W., W. Overwijk, R. S. Chamberlain, S. A. Rosenberg, B. Moss, and N. P. Restifo. 1997. Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a murine tumor model. Vaccine 15:387-394.
    • (1997) Vaccine , vol.15 , pp. 387-394
    • Carroll, M.W.1    Overwijk, W.2    Chamberlain, R.S.3    Rosenberg, S.A.4    Moss, B.5    Restifo, N.P.6
  • 13
    • 0031017252 scopus 로고    scopus 로고
    • Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endo-genously during viral infection
    • Cousens, L. P., J. S. Orange, H. C. Sue, and C. A. Biron. 1997. Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endo-genously during viral infection. Proc. Natl. Acad. Sci. USA 94:634-639.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 634-639
    • Cousens, L.P.1    Orange, J.S.2    Sue, H.C.3    Biron, C.A.4
  • 14
    • 0001636408 scopus 로고
    • Poxvirus recombinants as live vaccines
    • M. M. Binns and G. L. Smith (ed.). CRC Press, Boca Raton, Fla.
    • Cox, W. I., J. Tartaglia, and E. Paoletti. 1992. Poxvirus recombinants as live vaccines, p. 123-162. In M. M. Binns and G. L. Smith (ed.), Recombinant poxviruses. CRC Press, Boca Raton, Fla.
    • (1992) Recombinant Poxviruses , pp. 123-162
    • Cox, W.I.1    Tartaglia, J.2    Paoletti, E.3
  • 15
    • 0023395846 scopus 로고
    • Isolation and characterization of attenuated mutants of vaccinia virus
    • Dallo, S., and M. Esteban. 1987. Isolation and characterization of attenuated mutants of vaccinia virus. Virology 159:408-422.
    • (1987) Virology , vol.159 , pp. 408-422
    • Dallo, S.1    Esteban, M.2
  • 16
    • 0024443825 scopus 로고
    • Humoral immune response elicited by highly attenuated variants of vaccinia virus and by an attenuated recombinant expressing HIV-1 envelope protein
    • Dallo, S., J.-S. Maa, J. R. Rodriguez, D. Rodriguez, and M. Esteban. 1989. Humoral immune response elicited by highly attenuated variants of vaccinia virus and by an attenuated recombinant expressing HIV-1 envelope protein. Virology 173:323-329.
    • (1989) Virology , vol.173 , pp. 323-329
    • Dallo, S.1    Maa, J.-S.2    Rodriguez, J.R.3    Rodriguez, D.4    Esteban, M.5
  • 17
    • 0031974691 scopus 로고    scopus 로고
    • Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells
    • Drexler, I., K. Heller, B. Wahren, V. Erfle, and G. Sutter. 1998. Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells. J. Gen. Virol. 79:347-352.
    • (1998) J. Gen. Virol. , vol.79 , pp. 347-352
    • Drexler, I.1    Heller, K.2    Wahren, B.3    Erfle, V.4    Sutter, G.5
  • 18
    • 0032145732 scopus 로고    scopus 로고
    • The immunogenicity and efficacy of intranasally or parenterally administered replication-deficient vaccinia-parainfluenza virus type 3 recombinants in rhesus monkeys
    • Durbin, A. P., L. S. Wyatt, J. Siew, B. Moss, and B. R. Murphy. 1998. The immunogenicity and efficacy of intranasally or parenterally administered replication-deficient vaccinia-parainfluenza virus type 3 recombinants in rhesus monkeys. Vaccine 16:1324-1330.
    • (1998) Vaccine , vol.16 , pp. 1324-1330
    • Durbin, A.P.1    Wyatt, L.S.2    Siew, J.3    Moss, B.4    Murphy, B.R.5
  • 19
    • 17144457249 scopus 로고
    • Risks and benefits of vaccinia vaccine use in the worldwide smallpox eradication campaign
    • Fenner, F. 1989. Risks and benefits of vaccinia vaccine use in the worldwide smallpox eradication campaign. Res. Virol. 140:465-466.
    • (1989) Res. Virol. , vol.140 , pp. 465-466
    • Fenner, F.1
  • 20
    • 0033151996 scopus 로고    scopus 로고
    • IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 env in a dose-dependent manner
    • Gherardi, M. M., J. C. Ramirez, D. Rodriguez, J. R. Rodriguez, G. Sano, F. Zavala, and M. Esteban. 1999. IL-12 delivery from recombinant vaccinia virus attenuates the vector and enhances the cellular immune response against HIV-1 env in a dose-dependent manner. J. lmmunol. 162:6724-6733.
    • (1999) J. Lmmunol. , vol.162 , pp. 6724-6733
    • Gherardi, M.M.1    Ramirez, J.C.2    Rodriguez, D.3    Rodriguez, J.R.4    Sano, G.5    Zavala, F.6    Esteban, M.7
  • 22
    • 15144345621 scopus 로고    scopus 로고
    • Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice
    • Hanke, T., T. J. Blanchard, J. Schneider, G. S. Ogg, R. Tan, M. Becker, S. C. Gilbert, A. V. S. Hill, G. L. Smith, and A. McMichael. 1998. Immunogenicities of intravenous and intramuscular administrations of modified vaccinia virus Ankara-based multi-CTL epitope vaccine for human immunodeficiency virus type 1 in mice. J. Gen. Virol. 79:83-90.
    • (1998) J. Gen. Virol. , vol.79 , pp. 83-90
    • Hanke, T.1    Blanchard, T.J.2    Schneider, J.3    Ogg, G.S.4    Tan, R.5    Becker, M.6    Gilbert, S.C.7    Hill, A.V.S.8    Smith, G.L.9    McMichael, A.10
  • 23
    • 0029940996 scopus 로고    scopus 로고
    • Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara
    • Hirsch, V., T. R. Fuerst, G. Sutter, M. W. Carroll, L. C. Yang, S. Golstein, M. Piatak, W. R. Elkins, W. G. Alvord, D. Montefiori, B. Moss, and J. D. Lifson. 1996. Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara. J. Virol. 70:3741-3752.
    • (1996) J. Virol. , vol.70 , pp. 3741-3752
    • Hirsch, V.1    Fuerst, T.R.2    Sutter, G.3    Carroll, M.W.4    Yang, L.C.5    Golstein, S.6    Piatak, M.7    Elkins, W.R.8    Alvord, W.G.9    Montefiori, D.10    Moss, B.11    Lifson, J.D.12
  • 27
    • 0027190418 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of production of multiple lymphokines by in vivo administration of dexamethasone
    • Kunicka, J. E., M. A. Talle, G. H. Denhart, M. Brown, C. A. Prince, and G. Goldstein. 1993. Immunosuppression by glucocorticoids: inhibition of production of multiple lymphokines by in vivo administration of dexamethasone. Cell. Immunol. 149:39-49.
    • (1993) Cell. Immunol. , vol.149 , pp. 39-49
    • Kunicka, J.E.1    Talle, M.A.2    Denhart, G.H.3    Brown, M.4    Prince, C.A.5    Goldstein, G.6
  • 30
    • 0015976094 scopus 로고
    • Lack of correlation between cell-mediated immunity to the carrier and the carrier-hapten helper effect
    • Liew, F. Y., and C. R. Parish. 1974. Lack of correlation between cell-mediated immunity to the carrier and the carrier-hapten helper effect. J. Exp. Med. 139:779-784.
    • (1974) J. Exp. Med. , vol.139 , pp. 779-784
    • Liew, F.Y.1    Parish, C.R.2
  • 31
    • 0011880157 scopus 로고
    • Vaccinia virus: A selectable eukaryotic cloning and expression vector
    • Mackett, M., G. L. Smith, and B. Moss. 1982. Vaccinia virus: a selectable eukaryotic cloning and expression vector. Proc. Natl. Acad. Sci. USA 79: 7415-7419.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 7415-7419
    • Mackett, M.1    Smith, G.L.2    Moss, B.3
  • 32
    • 0016721708 scopus 로고
    • Abstammung, eigenschaftenund verwendung des attenuierten vaccinia-stammes MVA
    • Mayr, A., V. Hoschstein-Mintzel, and H. Stickl. 1975. Abstammung, eigenschaftenund Verwendung des attenuierten Vaccinia-Stammes MVA. Infection 3:6-16.
    • (1975) Infection , vol.3 , pp. 6-16
    • Mayr, A.1    Hoschstein-Mintzel, V.2    Stickl, H.3
  • 33
    • 0018246525 scopus 로고
    • The smallpox vaccination strain MVA: Marker, genetic structure, experience gained with the parenteral vaccination and behaviour in organisms with a debilitated defence mechanism
    • Mayr, A., H. Stickl, H. K. Muller, K. Denner, and H. Singer. 1978. The smallpox vaccination strain MVA: marker, genetic structure, experience gained with the parenteral vaccination and behaviour in organisms with a debilitated defence mechanism. Zentbl. Backteriol. Hyg. B 167:375-390.
    • (1978) Zentbl. Backteriol. Hyg. B , vol.167 , pp. 375-390
    • Mayr, A.1    Stickl, H.2    Muller, H.K.3    Denner, K.4    Singer, H.5
  • 34
    • 0025876805 scopus 로고
    • Mapping of deletions in the genome of highly attenuated vaccinia virus MVA and their influence on virulence
    • Meyer, H., G. Sutter, and A. Mayr. 1991. Mapping of deletions in the genome of highly attenuated vaccinia virus MVA and their influence on virulence. J. Gen. Virol. 72:1031-1038.
    • (1991) J. Gen. Virol. , vol.72 , pp. 1031-1038
    • Meyer, H.1    Sutter, G.2    Mayr, A.3
  • 36
    • 0033566953 scopus 로고    scopus 로고
    • Intracellular rate-limiting steps in MHC class I antigen processing
    • Montoya, M., and M. del Val. 1999. Intracellular rate-limiting steps in MHC class I antigen processing. J. Immunol. 163:1914-1922.
    • (1999) J. Immunol. , vol.163 , pp. 1914-1922
    • Montoya, M.1    Del Val, M.2
  • 38
    • 0031966005 scopus 로고    scopus 로고
    • How the MHC selects Th1/Th2 immunity?
    • Murray, J. S. 1998. How the MHC selects Th1/Th2 immunity? Immunol Today 19:157-163.
    • (1998) Immunol Today , vol.19 , pp. 157-163
    • Murray, J.S.1
  • 39
    • 0020170245 scopus 로고
    • Construction of poxvirus as cloning vectors: Insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus
    • Panicali, D., and E. Paoletti. 1982. Construction of poxvirus as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus. Proc. Natl. Acad. Sci. USA 79: 4927-4931.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 4927-4931
    • Panicali, D.1    Paoletti, E.2
  • 40
    • 0029850548 scopus 로고    scopus 로고
    • Immune deviation: A historical perspective
    • Parish, C. R. 1996. Immune deviation: a historical perspective. Immunol. Cell Biol. 74:449-456.
    • (1996) Immunol. Cell Biol. , vol.74 , pp. 449-456
    • Parish, C.R.1
  • 41
    • 0023114641 scopus 로고
    • Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease
    • Redfield, R. R., D. C. Wright, W. D. James, T. S. Jones, C. Brown, and D. S. Burke. 1987. Disseminated vaccinia in a military recruit with human immunodeficiency virus (HIV) disease. N, Engl. J. Med. 316:673-676.
    • (1987) N, Engl. J. Med. , vol.316 , pp. 673-676
    • Redfield, R.R.1    Wright, D.C.2    James, W.D.3    Jones, T.S.4    Brown, C.5    Burke, D.S.6
  • 43
    • 0023968084 scopus 로고
    • Expression of the firefly luciferase gene in vaccinia virus: A highly sensitive gene marker to follow virus dissemination in tissues of infected animals
    • Rodríguez, J. F., D. Rodríguez, J. R. Rodríguez, E. B. McGowan, and M. Esteban. 1988. Expression of the firefly luciferase gene in vaccinia virus: a highly sensitive gene marker to follow virus dissemination in tissues of infected animals. Proc. Natl. Acad. Sci. USA 85:1667-1671.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1667-1671
    • Rodríguez, J.F.1    Rodríguez, D.2    Rodríguez, J.R.3    McGowan, E.B.4    Esteban, M.5
  • 44
    • 0344489867 scopus 로고    scopus 로고
    • Characterization of early stages in vaccinia virus membrane biogenesis: Implications of the 21-kilodalton protein and a newly identified 15-kilodalton envelope protein
    • Rodríguez, J. R., C. Risco, J. L. Carrascosa, M. Esteban, and D. Rodríguez. 1997. Characterization of early stages in vaccinia virus membrane biogenesis: implications of the 21-kilodalton protein and a newly identified 15-kilodalton envelope protein. J. Virol. 71:1821-1833.
    • (1997) J. Virol. , vol.71 , pp. 1821-1833
    • Rodríguez, J.R.1    Risco, C.2    Carrascosa, J.L.3    Esteban, M.4    Rodríguez, D.5
  • 45
    • 0030843346 scopus 로고    scopus 로고
    • The role of cellular immunity in protection against HIV infection
    • Rowland-Jones, S., R. Tan, and A. J. McMichael. 1997. The role of cellular immunity in protection against HIV infection. Adv. Immunol. 65:277-346.
    • (1997) Adv. Immunol. , vol.65 , pp. 277-346
    • Rowland-Jones, S.1    Tan, R.2    McMichael, A.J.3
  • 46
    • 0030945995 scopus 로고    scopus 로고
    • Characterization of early cytokine responses and an interleukin (IL-6)-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection
    • Ruzek, M. C., A. H. Millert, S. M. Opal, B. D. Pearce, and C. A. Biron. 1997. Characterization of early cytokine responses and an interleukin (IL-6)-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J. Exp. Med. 185:1185-1192.
    • (1997) J. Exp. Med. , vol.185 , pp. 1185-1192
    • Ruzek, M.C.1    Millert, A.H.2    Opal, S.M.3    Pearce, B.D.4    Biron, C.A.5
  • 47
    • 0021357086 scopus 로고
    • Inhibition of T cell-mediated cytotoxicity by anti-inflammatory steroids
    • Scheleimer, R. P., A. Jacques, H. S. Shin, L. M. Lichstein, and M. Plaut, 1984. Inhibition of T cell-mediated cytotoxicity by anti-inflammatory steroids. J. Immunol. 132:266-271.
    • (1984) J. Immunol. , vol.132 , pp. 266-271
    • Scheleimer, R.P.1    Jacques, A.2    Shin, H.S.3    Lichstein, L.M.4    Plaut, M.5
  • 49
  • 50
    • 0032544063 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer
    • Seth, A., I. Ourmanov, M. J. Kuroda, J. E. Schmitz, M. W. Carroll, L. S. Wyatt, B. Moss, M. A. Forman, V. M. Hirsch, and N. L. Letvin. 1998. Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer. Proc. Natl. Acad. Sci. USA 95:10112-10116.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10112-10116
    • Seth, A.1    Ourmanov, I.2    Kuroda, M.J.3    Schmitz, J.E.4    Carroll, M.W.5    Wyatt, L.S.6    Moss, B.7    Forman, M.A.8    Hirsch, V.M.9    Letvin, N.L.10
  • 53
    • 0026442276 scopus 로고
    • Nonreplicating vaccinia vector efficiently expresses recombinant genes
    • Sutter, G., and B. Moss. 1992. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc. Natl. Acad. Sci. USA 89:10847-10851.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10847-10851
    • Sutter, G.1    Moss, B.2
  • 54
    • 0028074787 scopus 로고
    • A recombinant vector derived from the host-range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus
    • Sutter, G., L. S. Wyatt, P. L. Foley, J. R. Bennink, and B. Moss. 1994. A recombinant vector derived from the host-range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus. Vaccine 12:1032-1040.
    • (1994) Vaccine , vol.12 , pp. 1032-1040
    • Sutter, G.1    Wyatt, L.S.2    Foley, P.L.3    Bennink, J.R.4    Moss, B.5
  • 55
    • 0026528306 scopus 로고
    • Nonreplicating viral vectors as potential vaccines: Recombinant canarypox virus expressing measles virus fusion (F) and hemagglutinin (HA) glycoproteins
    • Taylor, J., R. Weinberg, J. Tartaglia, C. Richardson, G. Alkhatib, D. Breidis, M. Appel, E. Norton, and E. Paoletti. 1992. Nonreplicating viral vectors as potential vaccines: recombinant canarypox virus expressing measles virus fusion (F) and hemagglutinin (HA) glycoproteins. Virology 187:321-328.
    • (1992) Virology , vol.187 , pp. 321-328
    • Taylor, J.1    Weinberg, R.2    Tartaglia, J.3    Richardson, C.4    Alkhatib, G.5    Breidis, D.6    Appel, M.7    Norton, E.8    Paoletti, E.9
  • 56
    • 0019152303 scopus 로고
    • Studies on poxvirus infection in irradiated animals
    • Werner, G. T., U. Jentsch, E. Metzger, and J. Simon. 1980. Studies on poxvirus infection in irradiated animals. Arch, Virol. 64:247-256.
    • (1980) Arch, Virol. , vol.64 , pp. 247-256
    • Werner, G.T.1    Jentsch, U.2    Metzger, E.3    Simon, J.4
  • 57
    • 84909844561 scopus 로고
    • The global eradication of smallpox. Final report of the global commission for the certification of smallpox eradication
    • World Health Organization, Geneva, Switzerland
    • World Health Organization. 1980. The global eradication of smallpox. Final report of the global commission for the certification of smallpox eradication. History of international public health, no. 4. World Health Organization, Geneva, Switzerland.
    • (1980) History of International Public Health , vol.4
  • 58
    • 0029033825 scopus 로고
    • Replication-deficient vaccinia virus encoding bacteriophage T7 RNA polymerase for transient gene expression in mammalian cells
    • Wyatt, L., B. Moss, and S. Rozenblatt. 1995. Replication-deficient vaccinia virus encoding bacteriophage T7 RNA polymerase for transient gene expression in mammalian cells. Virology 210:202-205.
    • (1995) Virology , vol.210 , pp. 202-205
    • Wyatt, L.1    Moss, B.2    Rozenblatt, S.3
  • 59
    • 0030446387 scopus 로고    scopus 로고
    • Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model
    • Wyatt, L., S. T. Shors, B. R. Murphy, and B. Moss. 1996. Development of a replication-deficient recombinant vaccinia virus vaccine effective against parainfluenza virus 3 infection in an animal model. Vaccine 14:1451-1458.
    • (1996) Vaccine , vol.14 , pp. 1451-1458
    • Wyatt, L.1    Shors, S.T.2    Murphy, B.R.3    Moss, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.