Cutting Edge: Long-Term B Cell Memory in Humans after Smallpox Vaccination

Journal of Immunology

Volumn 171, Issue 10, 2003, Pages 4969-4973

  Crotty, Shane ^a,d   Felgner, Phil ^b   Davies, Huw ^b,c   Glidewell, John ^a   Villarreal, Luis ^b   Ahmed, Rafi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; IMMUNOGLOBULIN G; SMALLPOX VACCINE;

ADOLESCENT; ADULT; ANTIBODY RESPONSE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; LONGEVITY; MALE; MEMORY CELL; NORMAL HUMAN; PRIORITY JOURNAL; SMALLPOX; T LYMPHOCYTE;

EID: 0242495755     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.10.4969     Document Type: Article

References (25)

1. Crotty, S., and R. Ahmed. 2003. Immunological memory. In Topley and Wilson's Microbiology and Microbial Infections, Immunology Volume. S. H. E. Kaufmann and M. Steward, eds. Arnold, London. In press.
2. Plotkin, S. A., and W. A. Orenstein. 1999. Vaccines. W. B. Saunders Co., Philadelphia.
3. Crotry, S., E. N. Kersh, J. Cannons, P. L. Schwartzberg, and R. Ahmed. 2003. SAP is required for generating long-term humoral immunity. Nature 421:282.
4. Manz, R. A., S. Arce, G. Cassese, A. E. Hauser, F. Hiepe, and A. Radbruch. 2002. Humoral immunity and long-lived plasma cells. Curr. Opin. Immunol. 14:517.
5. Slifka, M. K., R. Antia, J. K. Whitmire, and R. Ahmed. 1998. Humoral immunity due to long-lived plasma cells. Immunity 8:363.
6. Bernasconi, N. L., E. Traggiai, and A. Lanzavecchia. 2002. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 298:2199.
7. Maruyama, M., K. P. Lam, and K. Rajewsky. 2000. Memory B-cell persistence is independent of persisting immunizing antigen. Nature 407:636.
8. Fenner, F., D. A. Henderson, I. Arita, Z. Jezek, and I. D. Ladnyi. 1988. Smallpox and Its Eradication. World Health Organization, Geneva.
9. Fauci, A. S. 2002. Smallpox vaccination policy-the need for dialogue. N. Engl. J. Med. 346:1319.
10. Harrington, L. E., R. Most Rv, J. L. Whitton, and R. Ahmed. 2002. Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J. Virol. 76:3329.
11. Tsung, K., J. H. Yim, W. Marti, R. M. Buller, and J. A. Norton. 1996. Gene expression and cytopathic effect of vaccinia virus inactivated by psoralen and long-wave UV light. J. Virol. 70:165.
12. Hartmann, G., R. D. Weeratna, Z. K. Ballas, P. Payette, S. Blackwell, I. Suparto, W. L. Rasmussen, M. Waldschmidt, D. Sajuthi, R. H. Purcell, et al. 2000. Delineation of a CpG phosphorothioate oligodeoxynuc]eotide for activating primate immune responses in vitro and in vivo. J. Immunol. 164:1617.
13. Frey, S. E., F. K. Newman, J. Cruz, W. B. Shelton, J. M. Tennant, T. Polach, A. L. Rothman, J. S. Kennedy, M. Wolff, R. B. Belshe, and F. A. Ennis. 2002. Dose-related effects of smallpox vaccine. N. Engl. J. Med. 346:1275.
14. el-Ad, B., Y. Roth, A. Winder, Z. Tochner, T. Lublin-Tennenbaum, E. Katz, and T. Schwartz. 1990. The persistence of neutralizing antibodies after revaccination against smallpox. J. Infect. Dis. 161:446.
15. Lin, C. L., C. S. Chung, H. G. Heine, and W. Chang. 2000. Vaccinia virus envelope H3L protein binds to cell surface heparan sulfate and is important for intracellular mature virion morphogenesis and virus infection in vitro and in vivo. J. Virol. 74:3353.
16. Demkowicz, W. E., Jr., R. A. Littaua, J. Wang, and F. A. Ennis. 1996. Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J. Virol. 70:2627.
17. Frelinger, J. A., and M. L. Garba. 2002. Responses to smallpox vaccine. N. Engl. J. Med. 347:689.
18. Rappuoli, R., H. I. Miller, and S. Falkow. 2002. Medicine: the intangible value of vaccination. Science 297:937.
19. Mandel, T. E., R. P. Phipps, A. Abbot, and J. G. Tew. 1980. The follicular dendritic cell: long term antigen retention during immunity. Immunol. Rev. 53:29.
20. Kempe, C. H., C. Bowles, G. Meiklejohn, T. O. Berge, L. St. Vincent, B. V. Sundara Babu, S. Govindarajan, N. R. Ratnakannan, A. W. Downie, and V. R. Murthy. 1961. The use of vaccinia hyperimmune γ-globulin in the prophylaxis of smallpox. Bull. W. H. O. 25:41.
21. + cytotoxic T lymphocytes and interferon-γ-producing T cells after smallpox vaccination. J. Infect. Dis. 185:1657.
22. Mack, T. M. 1972. Smallpox in Europe, 1950-1971. J. Infect. Dis. 125:161.
23. Arita, I. 2002. Duration of immunity after smallpox vaccination: a study on vaccination policy against smallpox bioterrorism in Japan. Jpn. J. Infect. Dis. 55:112.
24. Pedersen, K., E. J. Snijder, S. Schleich, N. Roos, G. Griffiths, and J. K. Locker. 2000. Characterization of vaccinia virus intracellular cores: implications for viral uncoating and core structure. J. Virol. 74:3525.
25. Hammarlund, E., M. W. Lewis, S. G. Hansen, L. I. Strelow, J. A. Nelson, G. J. Sexton, J. M. Hanifin, and M. K. Slifka. 2003. Duration of antiviral immunity after smallpox vaccination. Nat. Med. 9:1131.