A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 1, 2004, Pages 290-295

  Prieur, Eric ^a,b,d   Gilbert, Sarah C ^b   Schneider, Joerg ^c   Moore, Anne C ^a   Sheu, Eric G ^a   Goonetilleke, Nilu ^a   Robson, Kathryn J H ^d   Hill, Adrian V S ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Oxxon Pharmaccines Ltd   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBOSPONDIN RELATED ADHESIVE PROTEIN; CD8 ANTIGEN; DEOXYRIBONUCLEOPROTEIN; DNA VACCINE; GAMMA INTERFERON; LIVER STAGE ANTIGEN 1 ANTIBODY; MALARIA VACCINE; PLASMID DNA; POLYPROTEIN; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EXPRESSION VECTOR; FOWLPOX VIRUS; IMMUNOGENETICS; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; POXVIRUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPOROZOITE; T LYMPHOCYTE; VACCINIA VIRUS; VIRUS RECOMBINANT; VIRUS STRAIN;

ANIMALS; ANTIGENS, PROTOZOAN; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; FOWLPOX VIRUS; GENETIC VECTORS; INTERFERON TYPE II; MALARIA VACCINES; MALARIA, FALCIPARUM; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; VACCINES, DNA; VACCINIA VIRUS;

ANIMALIA; DNA VIRUSES; FOWLPOX VIRUS; PLASMODIUM FALCIPARUM; POXVIRIDAE; PROTOZOA; VACCINIA VIRUS; VECTORS;

EID: 0347088996     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307158101     Document Type: Article

References (43)

1. Miller, L. H. & Hoffman, S. L. (1998) Nat. Med. 4, 520-524.
2. Nussenzweig, R. S., Vanderberg, J., Most, H. & Orton, C. (1967) Nature 216, 160-162.
3. Edelman, R., Hoffman, S. L., Davis, J. R., Beier, M., Sztein, M. B., Losonsky, G., Herrington, D. A., Eddy, H. A., Hollingdale, M. R., Gordon, D. M., et al. (1993) J. Infect. Dis. 168, 1066-1070.
4. Miller, L.-H., Baruch, D.-I., Marsh, K. & Doumbo, O.-K. (2002) Nature 415, 673-679.
5. Plebanski, M. & Hill, A. V. (2000) Curr. Opin. Immunol. 12, 437-441.
6. Renggli, J., Hahne, M., Matile, H., Betschart, B., Tschopp, J. & Corradin, G. (1997) Parasite Immunol. 19, 145-148.
7. Weiss, W. R., Sedegah, M., Beaudoin, R. L., Miller, L. H. & Good, M. F. (1988) Proc. Natl. Acad. Sci. USA 85, 573-576.
8. Ferreira, A., Schofield, L., Enea, V., Schellekens, H., van-der-Meide, P., Collins, W. E., Nussenzweig, R. S. & Nussenzweig, V. (1986) Science 232, 881-884.
9. Seguin, M. C., Klotz, F. W., Schneider, I., Weir, J. P., Goodbary, M., Slayter, M., Raney, J. J., Aniagolu, J. U. & Green, S. J. (1994) J. Exp. Med. 180, 353-358.
10. Doolan, D. L. & Hoffman, S. L. (1999) J. Immunol. 163, 884-892.
11. Hill, A. V., Allsopp, C. E., Kwiatkowski, D., Anstey, N. M., Twumasi, P., Rowe, P. A., Bennett, S., Brewster, D., McMichael, A. J. & Greenwood, B. M. (1991) Nature 352, 595-600.
12. Seder, R. A. & Hill, A. V. (2000) Nature 406, 793-798.
13. Schneider, J., Gilbert, S. C., Hannan, C. M., Degano, P., Prieur, E., Sheu, E. G., Plebanski, M. & Hill, A. V. (1999) Immunol. Rev. 170, 29-38.
14. Schneider, J., Gilbert, S. C., Blanchard, T. J., Hanke, T., Robson, K. J., Hannan, C. M., Becker, M., Sinden, R., Smith, G. L. & Hill, A. V. (1998) Nat. Med. 4, 397-402.
15. Sedegah, M., Jones, T. R., Kaur, M., Hedstrom, R., Hobart, P., Tine, J. A. & Hoffman, S. L. (1998) Proc. Natl. Acad. Sci. USA 95, 7648-7653.
16. Gilbert, S.-C., Schneider, J., Hannan, C.-M., Hu, J.-T., Plebanski, M., Sinden, R. & Hill, A.-V. S. (2002) Vaccine 20, 1039-1045.
17. Barouch, D.-H., Kunstman, J., Kuroda, M.-J., Schmitz, J.-E., Santra, S., Peyerl, F.-W., Krivulka, G.-R., Beaudry, K., Lifton, M.-A., Gorgone, D.-A., et al. (2002) Nature 415, 335-339.
18. Vogel, T. U., Friedrich, T. C., O'Connor, D. H., Rehrauer, W., Dodds, E. J., Hickman, H., Hildebrand, W., Sidney, J., Sette, A., Hughes, A., et al. (2002) J. Virol. 76, 11623-11636.
19. Doolan, D. L., Sedegah, M., Hedstrom, R. C., Hobart, P., Charoenvit, Y. & Hoffman, S. L. (1996) J. Exp. Med. 183, 1739-1746.
20. Doolan, D. L., Hoffman, S. L., Southwood, S., Wentworth, P. A., Sidney, J., Chesnut, R. W., Keogh, E., Appella, E., Nutman, T. B., Lai, A. A., et al. (1997) Immunity 7, 97-112.
21. Plebanski, M., Aidoo, M., Whittle, H. C. & Hill, A. V. (1997) J. Immunol. 158, 2849-2855.
22. Aidoo, M., Lalvani, A., Gilbert, S. C., Hu, J. T., Daubersies, P., Hurt, N., Whittle, H. C., Druihle, P. & Hill, A. V. (2000) Infect. Immun. 68, 227-232.
23. Daubersies, P., Thomas, A. W., Millet, P., Brahimi, K., Langermans, J. A., Ollomo, B., BenMohamed, L., Slierendregt, B., Eling, W., Van-Belkum, A., et al. (2000) Nat. Med. 6, 1258-1263.
24. Fidock, D. A., Bottius, E., Brahimi, K., Moelans, I. I., Aikawa, M., Konings, R. N., Certa, U., Olafsson, P., Kaidoh, T., Asavanich, A., et al. (1994) Mol. Biochem. Parasitol. 64, 219-232.
25. Hope, I. A., Hall, R., Simmons, D. L., Hyde, J. E. & Scaife, J. G. (1984) Nature 308, 191-194.
26. Moelans, I. I., Meis, J. F., Kocken, C., Konings, R. N. & Schoenmakers, J. G. (1991) Mol. Biochem. Parasitol. 45, 193-204.
27. Robson, K. J., Hall, J. R., Jennings, M. W., Harris, T. J., Marsh, K., Newbold, C. I., Tate, V. E. & Weatherall, D. J. (1988) Nature 335, 79-82.
28. Guerin-Marchand, C., Druilhe, P., Galey, B., Londono, A., Patarapotikul, J., Beaudoin, R. L., Dubeaux, C., Tartar, A., Mercereau-Puijalon, O. & Langsley, G. (1987) Nature 329, 164-167.
29. Fidock, D. A., Gras-Masse, H., Lepers, J. P., Brahimi, K., Benmohamed, L., Mellouk, S., Guerin-Marchand, C., Londono, A., Raharimalala, L., Meis, J. F., et al. (1994) J. Immunol. 153, 190-204.
30. Barnes, D. A., Wollish, W., Nelson, R. G., Leech, J. H. & Petersen, C. (1995) Exp. Parasitol. 81, 79-89.
31. Moelans, I. I., Cohen, J., Marchand, M., Molitor, C., de-Wilde, P., van-Pelt, J. F., Hollingdale, M. R., Roeffen, W. F., Eling, W. M., Atkinson, C. T., et al. (1995) Mol. Biochem. Parasitol. 72, 179-192.
32. Sultan, A. A., Thathy, V., Frevert, U., Robson, K. J., Crisanti, A., Nussenzweig, V., Nussenzweig, R. S. & Menard, R. (1997) Cell 90, 511-522.
33. Wizel, B., Houghten, R. A., Parker, K. C., Coligan, J. E., Church, P., Gordon, D. M., Ballou, W. R. & Hoffman, S. L. (1995) J. Exp. Med. 182, 1435-1445.
34. Good, M. F., & Doolan, D. L. (1999) Curr. Opin. Immunol. 11, 412-419.
35. Rammensee, H. G., Friede, T. & Stevanoviic, S. (1995) Immunogenetics 41, 178-228.
36. Mackett, M. & Smith, G. L. (1986) J. Gen. Virol. 67, 2067-2082.
37. Dunbar, P. R., Ogg, G. S., Chen, J., Rust, N., van-der-Bruggen, P. & Cerundolo, V. (1998) Curr. Biol. 8, 413-416.
38. Lauer, G. M., Ouchi, K., Chung, R. T., Nguyen, T. N., Day, C. L., Purkis, D. R., Reiser, M., Kim, A. Y., Lucas, M., Klenerman, P., et al. (2002) J. Virol. 76, 6104-6113.
39. Irvine, K. R., Chamberlain, R. S., Shulman, E. P., Surman, D. R., Rosenberg, S. A. & Restifo, N. P. (1997) J. Natl. Cancer Inst. 89, 1595-1601.
40. Robinson, H. L., Montefiori, D. C., Johnson, R. P., Manson, K. H., Kalish, M. L., Lifson, J. D., Rizvi, T. A., Lu, S., Hu, S. L., Mazzara, G. P., et al. (1999) Nat. Med. 5, 526-534.
41. Hoffman, S. L., Rogers, W. O., Carucci, D. J. & Venter, J. C. (1998) Nat. Med. 4, 1351-1353.
42. Gardner, M. J., Hall, N., Fung, E., White, O., Berriman, M., Hyman, R. W., Carlton, J. M., Pain, A., Nelson, K. E., Bowman, S., et al. (2002) Nature 419, 498-511.
43. Florens, L., Washburn, M. P., Raine, J. D., Anthony, R. M., Grainger, M., Haynes, J. D., Moch, J. K., Muster, N., Sacci, J. B., Tabb, D. L., et al. (2002) Nature 419, 520-526.