Host range restricted, non-replicating vaccinia virus vectors as vaccine candidates

Advances in Experimental Medicine and Biology

Volumn 397, Issue , 1996, Pages 7-13

  Moss, Bernard ^a   Carroll, Miles W ^a   Wyatt, Linda S ^a   Bennink, Jack R ^a   Hirsch, Vanessa M ^a   Goldstein, Simoy ^a   Elkins, William R ^a   Fuerst, Thomas R ^b   Lifson, Jeffrey D ^b   Piatak, M ^b   Restifo, Nicholas P ^c   Overwijk, Willem ^c   Chamberlain, Ronald ^c   Rosenberg, Steven A ^c   Sutter, Gerd ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b Genelabs Incorporated   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VACCINE; VIRUS VECTOR;

CANCER CELL; CELL PROTECTION; CELLULAR IMMUNITY; CONFERENCE PAPER; DNA FLANKING REGION; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; PRIORITY JOURNAL; VACCINIA VIRUS; VIRUS REPLICATION;

EID: 9044232149     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-1382-1_2     Document Type: Conference Paper

References (35)

1. Andrew, M. E., Coupar, B. E. H., Ada, G. L. and Boyle, D. B., 1986, Cell-mediated immune response to influenza virus antigens expressed by vaccinia virus recombinants, Microb. Path. 1:443-452.
2. Bennink, J. R., Yewdell, J. W., Smith, J. W., Moller, C. and Moss, B., 1984, Recombinant vaccinia virus primes and stimulates influenza virus HA-specific CTL, Nature 311:578-579.
3. Bronte, V., Tsung, K., Rao, J. B., Chen, P. W., Wang, M., Rosenberg, S. A. and Restifo, N. P., 1995, IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases, J. Immunol. 154:5282-5292.
4. Buller, R. M., Chakrabarti, S., Cooper, J. A., Twardzik, D. R. and Moss, B., 1988, Deletion of the vaccinia virus growth factor gene reduces virus virulence, J. Virol. 62:866-877.
5. Buller, R. M. L., Smith, G. L., Cremer, K., Notkins, A. L. and Moss, B., 1985, Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative pheno-type, Nature 317:813-815.
6. Chakrabarti, S., Brechung, K. and Moss, B., 1985. Vaccinia virus expression vector: Coexpression of β-galactosidase provides visual screening of recombinant virus plaques, Mol. Cell. Biol. 5:3403-3409.
7. Cooney, E. L., Collier, A. C., Greenberg, P. D., Coombs, R. W., Zarling, J., Arditti, D. E., Hoffman, M. C., Hu, S. L. and Corey, L., 1991, Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein, Lancet 337: 567-572.
8. Cox, W. I., Tartaglia, J. and Paoletli, E., 1992, Poxvirus recombinants as live vaccines, Recombinant poxviruses. (Binns, M. M. and Smith, G. L., eds.), 123-162. CRC Press, Boca Raton.
9. Daniel, M. D., Kirchhoff, F., Czajak, S. C., Sehgal, P. K. and Desrosiers, R. C., 1992, Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene, Science 258:1938-1941.
10. Fenner, F., Henderson, D. A., Arita, I., Jezek, Z. and Ladnyi, I. D., 1988, Smallpox and its eradication, World Health Organization, Geneva.
11. Flexner, C., Hugin, A. and Moss, B., 1987, Prevention of vaccinia virus infection in immunodeficient nude mice by vector-directed IL-2 expression, Nature 330:259-262.
12. Giavedoni, L. D., Planelles, V., Haigwood, N. L., Ahmad, S., Kluge, J. D., Marthas, M. L., Gardner, M. B., Luciw, P. A. and Yilma, T. D., 1993, Immune response of rhesus macaques to recombinant simian immunodeficiency virus-gp130 does not protect from challenge infection, J. Virol. 67:577-583.
13. Goldstern, S., Elkins, W. R., London, W. T., Hahn, A., Goeken, R., Martin, J. E. and Hirsch, V. M., 1994, Immunization with whole inactivated vaccine protects from infection by SIV grown in human but not macaque cells, J. Med. Primatol. 23: 75-82.
14. Hirsch, V. M., Goldstein, S., Chanock, R., Elkins, W. R., Suiter, G., Moss, B., Sisler, J., Lifson, J. and Fuerst, T., 1995. Limited virus replication following SIV challenge of macaques immunized with attenuated MVA vaccinia expressing SIVsm env and gag-pol, Vaccines 95:195-200.
15. Hochstein-Mintzel, V., Huber, H. C. and Stickl, H., 1972, Virulenz und immunogenität eines modifizierten vaccinia-virus (Stamm MVA), Z. Immun.-Forsch. 144:140-145.
16. Hu, S.-L., Abrams, K., Barber, G. N., Moran, P. Zarling, J. M., Langlois, A. J., Kuller, L., Morton, W. R. and Beneviste, R. E., 1992, Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science 255:456-459.
17. Israel, Z. R., Edmonson, P. F., Maul, D. H., O'Neill, S. P., Mossman, S. P., Thiriart, C., Fabry, L., Van Opstal, O., Bruck, C., Bex, F., Burny, A., Fultz, P. N., Mullins, J. I. and Hoover, E. A., 1994, Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines, J. Virol. 68:1843-1853.
18. Johnson, P. R., Montefiori, D. C., Goldstein, S., Hamm, T. E., Zhou, J. Y., Kitov, S., Haigwood, N. L., Misher, L., London, W. T., Gerin, J. L., Allison, A., Purcell, R. H., Chanock, R. M. and Hirsch, V. M., 1992, Inactivated whole SIV vaccine in Macaques - evaluation of protective efficacy against challenge with cell-free virus or infected cells, AIDS Res. Human Retroviruses, 8:1501-1505.
19. Mackett, M., Smith, G. L. and Moss, B., 1982, Vaccinia virus: a selectable eukaryotic cloning and expression vector, Proc. Natl. Acad. Sci. USA, 79:7415-7419.
20. Mackett, M., Smith, G. L. and Moss, B., 1984, General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes, J. Virol. 49:857-864.
21. Mayr, A. and Danner, K., 1979, Bedeutung von tierpocken für den menschen nach aufhebung der pflichtimpfung gegen pocken, Berl. Münch. Tierärztl. Wochenschr. 92:251-256.
22. Mayr, A., Hochstein-Mintzel, V. and Stickl, H., 1975, Abstammung, eigenschaften und verwendung des attenuierten vaccinia-stammes MVA, Infection 3:6-14.
23. Mayr, A., Stickl, H., Müller, H. K., Danner, K. and Singer, H., 1978, Pockenimpfstamm MVA: marker, genetische Struktur, erfahrungen mit der parenteralen Schutzimpfung und verhalten im abwehrgeschwächten Organismus, Zbl. Bukt. Hyg. I.Abt. Ong. B 167:375-390.
24. Meyer, H., Sutter, G. and Mayr, A., 1991, Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence, J. Gen. Virol. 72:1031-1038.
25. Moss, B., 1991, Vaccinia virus: a tool for research and vaccine development. Science 252:1662-1667.
26. Panicali, D. and Paoletti, E., 1982, Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus, Proc. Natl. Acad. Sci. USA 79:4927-4931.
27. Ramshaw, A., Andrew, M. E., Phillips, S. M., Boyle, D. B. and Coupar, B. E. H., 1987, Recovery of immunodeficient mice from a vaccinia virus/IL-2 recombinant infection, Nature 329:545-546.
28. Stickl, H., Hochstein-Mintzel, V., Mayr, A., Huber, H. C., Schäfer, H. and Holzner, A., 1974, MVA-stufenimpfimg gegen pocken. Kleinische erprobung des attenuierten pocken-lebendimpfstoffes, stamm MVA. Dtsch. Med. Wschr. 99:2386-2392.
29. Sutter, G. and Moss, B., 1992, Nonreplicating vaccinia vector efficiently expresses recombinant genes, Proc. Natl. Acad. Sci. USA 89:10847-10851.
30. Sutter, G., Wyatt, L. S., Foley, P. L., Bennink, J. R. and Moss, B., 1994, A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus, Vaccine 12:1032-1040.
31. Tartaglia, J., Perkus, M. E., Taylor, J., Norton, E. K., Audonnet, J. C., Cox, W. I., Davis, S. W., Vanderhoeven, J., Meignier, B., Riviere, M., Languet, B. and Paoletti, E., 1992, NYVAC - A highly attenuated strain of vaccinia virus, Virology 188:217-232.
32. Taylor, J., Weinberg, R., Tartaglia, J., Richardson, C., Alkhatib, G., Breidis, D., Appel, M., Norton, E. and Paoletti, E., 1992, Nonreplicating viral vectors as potential vaccines: recombinant canarypox virus expressing measles virus fusion (F) and hemagglutinin (HA) glycoproteins, Virology 187:321-328.
33. Wang, M., Bronte, V., Chen, P. W., Gritz, L., Panicali, D., Rosenberg, S. A. and Restifo, N. P., 1995, Active immunotherapy of cancer with a non-replicating recombinant fowlpox virus encoding a model tumor-associated antigen. J. Immunol. 154:4685-4692.
34. Werner, G. T., Jentsch, U., Metzger, E. and Simon, J., 1980, Studies on poxvirus infection in irradiated animals, Arch. Virol. 64:247-256.
35. Yewdell, J. W., Bennink, J. R., Smith, G. L. and Moss, B., 1985, Influenza A virus nucleoprotein is a major target for cross-reactive anti-influenza virus cytotoxic T lymphocytes, Proc. Natl. Acad. Sci. USA 82:1785-1789.