Specific genetic modifications of domestic animals by gene targeting and animal cloning

Reproductive Biology and Endocrinology

Volumn 1, Issue , 2003, Pages

  Wang, Bin ^a   Zhou, Jiangfeng ^b  

^a Nexia Biotechnologies Inc   (Canada)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGRICULTURE; BIOMEDICINE; CLONING; DNA MODIFICATION; DOMESTIC ANIMAL; GENE FUNCTION; GENE MUTATION; GENE TARGETING; GENE TECHNOLOGY; HOMOLOGOUS RECOMBINATION; NONHUMAN; REVIEW; SOMATIC CELL; ANIMAL; ANIMAL EMBRYO; CAT; CATTLE; CYTOLOGY; EMBRYO TRANSFER; GENETIC RECOMBINATION; GENETICS; HISTOCOMPATIBILITY; IMMUNOGLOBULIN GENE; METHODOLOGY; MOUSE; MOUSE MUTANT; PLURIPOTENT STEM CELL; PRION; RABBIT; SHEEP; SWINE; TRANSGENIC ANIMAL; XENOGRAFT;

AMYLOID; PRNP PROTEIN, MOUSE; PROTEIN PRECURSOR;

AMYLOID; ANIMALS; ANIMALS, DOMESTIC; ANIMALS, GENETICALLY MODIFIED; CATS; CATTLE; CLONING, ORGANISM; EMBRYO TRANSFER; EMBRYO, MAMMALIAN; GENE TARGETING; GENES, IMMUNOGLOBULIN; MICE; MICE, KNOCKOUT; PLURIPOTENT STEM CELLS; PRIONS; PROTEIN PRECURSORS; RABBITS; RECOMBINATION, GENETIC; SHEEP; SWINE; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HETEROLOGOUS;

EID: 4344657820     PISSN: 14777827     EISSN: None     Source Type: Journal    
DOI: 10.1186/1477-7827-1-103     Document Type: Review

References (66)

1. Evans MJ, Kaufman MH: Establishment in culture of pluripotential cells from mouse embryos. Nature 1981, 292:154-156.
2. Martin GR: Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A 1981, 78:7634-7638.
3. Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O: Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 1987, 330:576-578.
4. Thomas KR, Capecchi MR: Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987, 51:503-512.
5. Houdebine LM: The methods to generate transgenic animals and to control transgene expression. J Biotechnol 2002, 98:145-160.
6. Wheeler MB: Development and validation of swine embryonic stem cells: a review. Reprod Fertil Dev 1994, 6:563-568.
7. Stice SL, Strelchenko NS, Keefer CL, Matthews L: Pluripotent bovine embryonic cell lines direct embryonic development following nuclear transfer. Biol Reprod 1996, 54:100-110.
8. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH: Viable offspring derived from fetal and adult mammalian cells. Nature 1997, 385:810-813.
9. DNA Replication, Repair, and Recombination In Molecular Cell Biology 3 Edition (Edited by: Harvey L, David B, Arnola B, Lawrence Z, Paul M, James D). New York: W.H. Freeman and Company 1997, 365-404.
10. Schiestl RH, Petes TD: Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1991, 88:7585-7589.
11. Bishop JO, Smith P: Mechanism of chromosomal integration of microinjected DNA. Mol Biol Med 1989, 6:283-298.
12. Hanson KD, Sedivy JM: Analysis of biological selections for high-efficiency gene targeting. Mol Cell Biol 1995, 15:45-51.
13. Capecchi MR: The new mouse genetics: altering the genome by gene targeting. Trends Genet 1989, 5:70-76.
14. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R: Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998, 394:369-374.
15. Kato Y, Tani T, Sotomaru Y, Kurokawa K, Kato J, Doguchi H, Yasue H, Tsunoda Y: Eight calves cloned from somatic cells of a single adult. Science 1998, 282:2095-2098.
16. Baguisi A, Behboodi E, Melican DT, Pollock JS, Destrempes MM, Cammuso C, Williams JL, Nims SD, Porter CA, Midura P, et al.: Production of goats by somatic cell nuclear transfer. Nat Biotechnol 1999, 17:456-461.
17. Keefer CL, Baldassarre H, Keyston R, Wang B, Bhatia B, Bilodeau AS, Zhou JF, Leduc M, Downey BR, Lazaris A, et al.: Generation of dwarf goat (Capra hircus) clones following nuclear transfer with transfected and nontransfected fetal fibroblasts and in vitro-matured oocytes. Biol Reprod 2001, 64:849-856.
18. Polejaeva IA, Chen SH, Vaught TD, Page RL, Mullins J, Ball S, Dai Y, Boone J, Walker S, Ayares DL, et al.: Cloned pigs produced by nuclear transfer from adult somatic cells. Nature 2000, 407:86-90.
19. Chesne P, Adenot PG, Viglietta C, Baratte M, Boulanger L, Renard JP: Cloned rabbits produced by nuclear transfer from adult somatic cells. Nat Biotechnol 2002, 20:366-369.
20. Shin T, Kraemer D, Pryor J, Liu L, Rugila J, Howe L, Buck S, Murphy K, Lyons L, Westhusin M: A cat cloned b y nuclear transplantation. Nature 2002, 415:859.
21. Schnieke AE, Kind AJ, Ritchie WA, Mycock K, Scott AR, Ritchie M, Wilmut I, Colman A, Campbell KH: Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts. Science 1997, 278:2130-2133.
22. Cibelli JB, Stice SL, Golueke PJ, Kane JJ, Jerry J, Blackwell C, Ponce de Leon FA, Robl JM: Cloned transgenic calves produced from nonquiescent fetal fibroblasts. Science 1998, 280:1256-1258.
23. McCreath KJ, Howcroft J, Campbell KH, Colman A, Schnieke AE, Kind AJ: Production of gene-targeted sheep by nuclear transfer from cultured somatic cells. Nature 2000, 405:1066-1069.
24. Lai L, Kolber-Simonds D, Park KW, Cheong HT, Greenstein JL, Im GS, Samuel M, Bonk A, Rieke A, Day BN, et al.: Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 2002, 295:1089-1092.
25. Deng C, Capecchi MR: Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol Cell Biol 1992, 12:3365-3371.
26. te Riele H, Maandag ER, Berns A: Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc Natl Acad Sci U S A 1992, 89:5128-5132.
27. Yanez RJ, Porter AC: A chromosomal position effect on gene targeting in human cells. Nucleic Acids Res 2002, 30:4892-4901.
28. Templeton NS, Roberts DD, Safer B: Efficient gene targeting in mouse embryonic stem cells. Gene Ther 1997, 4:700-709.
29. Sedivy JM, Dutriaux A: Gene targeting and somatic cell genetics - a rebirth or a coming of age? Trends Genet 1999, 15:88-90.
30. Denning C, Dickinson P, Burl S, Wylie D, Fletcher J, Clark AJ: Gene targeting in primary fetal fibroblasts from sheep and pig. Cloning Stem Cells 2001, 3:221-231.
31. Harrison SJ, Guidolin A, Faast R, Crocker LA, Giannakis C, D'Apice AJ, Nottle MB, Lyons I: Efficient generation of alpha(1,3) galactosyltransferase knockout porcine fetal fibroblasts for nuclear transfer. Transgenic Res 2002, 11:143-150.
32. Clark AJ, Burl S, Denning C, Dickinson P: Gene targeting in livestock: a preview. Transgenic Res 2000, 9:263-275.
33. Polejaeva IA, Campbell KH: New advances in somatic cell nuclear transfer: application in transgenesis. Theriogenology 2000, 53:117-126.
34. Kubota C, Yamakuchi H, Todoroki J, Mizoshita K, Tabara N, Barber M, Yang X: Six cloned calves produced from adult fibroblast cells after long-term culture. Proc Natl Acad Sci U S A 2000, 97:990-995.
35. Lanza RP, Cibelli JB, Blackwell C, Cristofalo VJ, Francis MK, Baerlocher GM, Mak J, Schertzer M, Chavez EA, Sawyer N, et al.: Extension of cell life-span and telomere length in animals cloned from senescent somatic cells. Science 2000, 288:665-669.
36. Denning C, Burl S, Ainslie A, Bracken J, Dinnyes A, Fletcher J, King T, Ritchie M, Ritchie WA, Rollo M, et al.: Deletion of the alpha(1,3) galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheet. Nat Biotechnol 2001, 19:559-562.
37. Dai Y, Vaught TD, Boone J, Chen SH, Phelps CJ, Ball S, Monahan JA, Jobst PM, McCreath KJ, Lamborn AE, et al.: Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs. Nat Biotechnol 2002, 20:251-255.
38. Shiels PG, Kind AJ, Campbell KH, Waddington D, Wilmut I, Colman A, Schnieke AE: Analysis of telomere lengths in cloned sheep. Nature 1999, 399:316-317.
39. Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE: Extension of life-span by introduction of telomerase into normal human cells. Science 1998, 279:349-352.
40. Szabo S, Folkman J, Vattay P, Morales RE, Pinkus GS, Kato K: Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats. Gastroenterology 1994, 106:1106-1111.
41. Jiang XR, Jimenez G, Chang E, Frolkis M, Kusler B, Sage M, Beeche M, Bodnar AG, Wahl GM, Tlsty TD, et al.: Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 1999, 21:111-114.
42. Ye Y, Niekrasz M, Kosanke S, Welsh R, Jordan HE, Fox JC, Edwards WC, Maxwell C, Cooper DK: The pig as a potential organ donor for man. A study of potentially transferable disease from donor pig to recipient man. Transplantation 1994, 57:694-703.
43. Yang X, Tian XC, Dai Y, Wang B: Transgenic farm animals: applications in agriculture and biomedicine. Biotechnology annual review 2000, 5:269-292.
44. Tearle RG, Tange MJ, Zannettino ZL, Katerelos M, Shinkel TA, Van Denderen BJ, Lonie AJ, Lyons I, Nottle MB, Cox T, et al.: The alpha-1,3-galactosyltransferase knockout mouse. Implications for xenotransplantation. Transplantation 1996, 61:13-19.
45. Ramsoondar JJ, Machaty Z, Costa C, Williams BL, Fodor WL, Bondioli KR: Production of {alpha}1,3-Galactosyltransferase-Knockout Cloned Pigs Expressing Human {alpha}1,2-Fucosylosyltransferase. Biol Reprod 2003, 2:2.
46. Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, Chen SH, Ball S, Specht SM, Polejaeva IA, Monahan JA, et al.: Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 2003, 299:411-414.
47. Scott MR, Will R, Ironside J, Nguyen HO, Tremblay P, DeArmond SJ, Prusiner SB: Compelling transgenic evidence for transmission of bovine spongiform encephalopathy prions to humans. Proc Natl Acad Sci U S A 1999, 96:15137-15142.
48. Prusiner SB: Novel proteinaceous infectious particles cause scrapie. Science 1982, 216:136-144.
49. DeArmond SJ, Bouzamondo E: Fundamentals of prion biology and diseases. Toxicology 2002, 181-182:9-16.
50. Collinge J, Whittington MA, Sidle KC, Smith CJ, Palmer MS, Clarke AR, Jefferys JG: Prion protein is necessary for normal synaptic function. Nature 1994, 370:295-297.
51. Brown DR, Qin K, Herms JW, Madlung A, Manson J, Strome R, Fraser PE, Kruck T, von Bohlen A, Schulz-Schaeffer W, et al.: The cellular prion protein binds copper in vivo. Nature 1997, 390:684-687.
52. Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ: Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies. Proc Natl Acad Sci U S A 1993, 90:10608-10612.
53. Bueler H, Raeber A, Sailer A, Fischer M, Aguzzi A, Weissmann C: High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med 1994, 1:19-30.
54. Robl JM, Kasinathan P, Sullivan E, Kuroiwa Y, Tomizuka K, Ishida I: Artificial chromosome vectors and expression of complex proteins in transgenic animals. Theriogenology 2003, 59:107-113.
55. Clark M: Antibody humanization: a case of the 'Emperor's new clothes'? Immunol Today 2000, 21:397-402.
56. Boulianne GL, Hozumi N, Shulman MJ: Production of functional chimaeric mouse/human antibody. Nature 1984, 312:643-646.
57. Aya J: Production of fully human antibodies by transgenic mice. Current Opinion in Biotechnology 1995, 6:561-566.
58. Lonberg N, Huszar D: Human antibodies from transgenic mice. Int Rev Immunol 1995, 13:65-93.
59. Mendez MJ, Green LL, Corvalan JR, Jia XC, Maynard-Currie CE, Yang XD, Gallo ML, Louie DM, Lee DV, Erickson KL, et al.: Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice. Nat Genet 1997, 15:146-156.
60. Green LL, Hardy MC, Maynard-Currie CE, Tsuda H, Louie DM, Mendez MJ, Abderrahim H, Noguchi M, Smith DH, Zeng Y, et al.: Antigen-specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs. Nat Genet 1994, 7:13-21.
61. Kuroiwa Y, Kasinathan P, Choi YJ, Naeem R, Tomizuka K, Sullivan EJ, Knott JG, Duteau A, Goldsby RA, Osborne BA, et al.: Cloned transchromosomic calves producing human immunoglobulin. Nat Biotechnol 2002, 20:889-894.
62. Grobet L, Martin LJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J, et al.: A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat Genet 1997, 17:71-74.
63. Elsea SH, Lucas RE: The mousetrap: what we can learn when the mouse model does not mimic the human disease. Ilar J 2002, 43:66-79.
64. Kent G, Iles R, Bear CE, Huan LJ, Griesenbach U, McKerlie C, Frndova H, Ackerley C, Gosselin D, Radzioch D, et al.: Lung disease in mice with cystic fibrosis. J Clin Invest 1997, 100:3060-3069.
65. Snouwaert JN, Brigman KK, Latour AM, Iraj E, Schwab U, Gilmour MI, Koller BH: A murine model of cystic fibrosis. Am J Respir Crit Care Med 1995, 151:S59-64.
66. Harris A: Towards an ovine model of cystic fibrosis. Hum Mol Genet 1997, 6:2191-2194.