Antibody humanization: A case of the 'Emperor's new clothes'?

Immunology Today

Volumn 21, Issue 8, 2000, Pages 397-402

  Clark, Mike ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CHIMERIC ANTIBODY; CYTOKINE; FC RECEPTOR; HUMAN IMMUNOGLOBULIN; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN ALLOTYPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G4; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; RECOMBINANT ANTIBODY;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY COMPLEX; ANTIGENICITY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; GLYCOSYLATION; HUMAN; IMMUNE STATUS; IMMUNOGENICITY; IMMUNOGLOBULIN VARIABLE REGION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; REVIEW; SCID MOUSE; SOMATIC MUTATION; TRANSGENIC MOUSE;

ANIMALS; ANTIBODIES, MONOCLONAL; DRUG DESIGN; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN VARIABLE REGION; MICE; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS;

EID: 0033866627     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(00)01680-7     Document Type: Review

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