γ-Hydroxybutyrate binds to the synaptic site recognizing succinate monocarboxylate: A new hypothesis on astrocyte-neuron interaction via the protonation of succinate

Journal of Neuroscience Research

Volumn 86, Issue 7, 2008, Pages 1566-1576

  Molnár, Tünde ^a   Barabás, Péter ^a   Héja, László ^a   Fekete, Erzsébet Kútiné ^a   Lasztóczi, Bálint ^a   Szabó, Pál ^a   Nyitrai, Gabriella ^a   Simon Trompler, Edit ^a   Hajós, Ferenc ^b   Palkovits, Miklós ^c   Kardos, Julianna ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b SZENT ISTVÁN UNIVERSITY   (Hungary)

^c SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Citrate; Epileptiform activity; Gamma hydroxybutyrate; Succinate; Synaptic binding

Indexed keywords

4 HYDROXYBUTYRIC ACID; 6,7,8,9 TETRAHYDRO 5 HYDROXY 5H BENZOCYCLOHEPT 6 YLIDENEACETIC ACID; ACETIC ACID DERIVATIVE; ALPHA CYANOHYDROXYCINNAMIC ACID; CARBENOXOLONE; CINNAMIC ACID DERIVATIVE; FLUFENAMIC ACID; HEMIESTER ETHYLHEMISUCCINATE; LACTIC ACID; LIGAND; OUABAIN; SUCCINATE MONOCARBOXYLATE; SUCCINIC ACID; SUCCINIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING AFFINITY; BINDING KINETICS; BRAIN MITOCHONDRION; CELL INTERACTION; CHEMICAL BINDING; CONTROLLED STUDY; EPILEPTIC DISCHARGE; FOREBRAIN; GAP JUNCTION; HUMAN; HUMAN TISSUE; HYPOTHESIS; NERVE CELL; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTON TRANSPORT; RAT; SYNAPSE;

EID: 43149106951     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21608     Document Type: Article

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