Metabolic GHB precursor succinate binds to γ-hydroxybutyrate receptors: Characterization of human basal ganglia areas nucleus accumbens and globus pallidus

Journal of Neuroscience Research

Volumn 84, Issue 1, 2006, Pages 27-36

  Molnár, Tünde ^a   Fekete, Erzsébet Kútiné ^a   Kardos, Julianna ^a   Simon Trompler, Edit ^a   Palkovits, Miklós ^b   Emri, Zsuzsa ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Carbenoxolone hemisuccinate; Drug of abuse; Extrasynaptic binding site; GABAb receptor subtype; GHB receptor subtype; Succinate; Synaptic binding site

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 HYDROXYBUTYRIC ACID; ARECAIDINE; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; CARBENOXOLONE HEMISUCCINATE; ETHYL HEMISUCCINATE; GLUCOCORTICOID RECEPTOR ANTAGONIST; LIGAND; SUCCINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; FOREBRAIN; GAP JUNCTION; GLOBUS PALLIDUS; HUMAN; HUMAN TISSUE; NONHUMAN; NUCLEUS ACCUMBENS; PRECURSOR; PRIORITY JOURNAL; RAT; SYNAPTIC MEMBRANE;

ANIMALS; BACLOFEN; BENZOCYCLOHEPTENES; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA AGONISTS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; HUMANS; MALE; MODELS, BIOLOGICAL; NUCLEUS ACCUMBENS; POSTMORTEM CHANGES; PROTEIN BINDING; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, CELL SURFACE; SUCCINIC ACID; SYNAPTOSOMES; TRITIUM;

EID: 33745796333     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20867     Document Type: Article

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