-
1
-
-
0036094576
-
Where does Parkinson disease pathology begin in the brain?
-
Del Tredici K., Rub U., De Vos R.A.I., Bohl J.R.E., and Braak H. Where does Parkinson disease pathology begin in the brain?. J Neuropathol Exp Neurol 61 5 (2002) 413
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, Issue.5
, pp. 413
-
-
Del Tredici, K.1
Rub, U.2
De Vos, R.A.I.3
Bohl, J.R.E.4
Braak, H.5
-
2
-
-
34447289622
-
Pathogenic mutations in Parkinson disease
-
Tan E.K., and Skipper L.M. Pathogenic mutations in Parkinson disease. Hum Mutat 28 7 (2007) 641
-
(2007)
Hum Mutat
, vol.28
, Issue.7
, pp. 641
-
-
Tan, E.K.1
Skipper, L.M.2
-
3
-
-
33750459730
-
Parkinsonism genes: culprits and clues
-
Abeliovich A., and Beal M.F. Parkinsonism genes: culprits and clues. J Neurochem 99 4 (2006) 1062
-
(2006)
J Neurochem
, vol.99
, Issue.4
, pp. 1062
-
-
Abeliovich, A.1
Beal, M.F.2
-
4
-
-
0027952849
-
Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study
-
Dexter D.T., Holley A.E., Flitter W.D., Slater T.F., Wells F.R., Daniel S.E., et al. Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study. Mov Disord 9 (1994) 92
-
(1994)
Mov Disord
, vol.9
, pp. 92
-
-
Dexter, D.T.1
Holley, A.E.2
Flitter, W.D.3
Slater, T.F.4
Wells, F.R.5
Daniel, S.E.6
-
5
-
-
0030805622
-
A generalized increase in protein carbonyls in the brain in Parkinson's disease but not incidental Lewy body disease
-
Alam Z.I., Daniel S.E., Lees A.J., Marsden C.D., Jenner P., and Halliwell B. A generalized increase in protein carbonyls in the brain in Parkinson's disease but not incidental Lewy body disease. J Neurochem 69 (1997) 1326
-
(1997)
J Neurochem
, vol.69
, pp. 1326
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, C.D.4
Jenner, P.5
Halliwell, B.6
-
6
-
-
0036570159
-
Oxidatively modified proteins in aging and disease
-
Beal M.F. Oxidatively modified proteins in aging and disease. Free Radic Biol Med 32 9 (2002) 797
-
(2002)
Free Radic Biol Med
, vol.32
, Issue.9
, pp. 797
-
-
Beal, M.F.1
-
7
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: a selective increase in 8-hydroxy-guanine in substantia nigra?
-
Alam Z.I., Jenner A., Daniel S.E., Lees A.J., Cairns N., Marsden C.D., et al. Oxidative DNA damage in the parkinsonian brain: a selective increase in 8-hydroxy-guanine in substantia nigra?. J Neurochem 69 (1997) 1196
-
(1997)
J Neurochem
, vol.69
, pp. 1196
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
-
8
-
-
0000232034
-
A marker of oxyradical-mediated DNA damage [8-hydroxy-2′-deoxyguanosine] is increased in nigrostriatum of Parkinson's disease brain
-
Sanchez-Ramos J., Overvik E., and Ames B.N. A marker of oxyradical-mediated DNA damage [8-hydroxy-2′-deoxyguanosine] is increased in nigrostriatum of Parkinson's disease brain. Neurodegeneration 3 (1994) 197
-
(1994)
Neurodegeneration
, vol.3
, pp. 197
-
-
Sanchez-Ramos, J.1
Overvik, E.2
Ames, B.N.3
-
9
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
Parker W.D., Boyson S.J., and Parks J.K. Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 26 (1989) 719
-
(1989)
Ann Neurol
, vol.26
, pp. 719
-
-
Parker, W.D.1
Boyson, S.J.2
Parks, J.K.3
-
10
-
-
0025254401
-
Complex I deficiency in Parkinson's disease
-
Schapira A.H., Cooper J.M., Dexter D., Clark J.B., Jenner P., and Marsden C.D. Complex I deficiency in Parkinson's disease. J Neurochem 54 (1990) 823
-
(1990)
J Neurochem
, vol.54
, pp. 823
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
11
-
-
0029050583
-
Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's Disease
-
Haas R.H., Nasirian F., Nakano K., Ward D., Pay R.N., Hill R., et al. Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's Disease. Ann Neurol 37 (1995) 714
-
(1995)
Ann Neurol
, vol.37
, pp. 714
-
-
Haas, R.H.1
Nasirian, F.2
Nakano, K.3
Ward, D.4
Pay, R.N.5
Hill, R.6
-
12
-
-
0028176592
-
An immunohistochemical study on αketoglutarate dehydrogenase complex in Parkinson's disease
-
Mizuno Y., Matsuda S., Yoshino H., Mori H., Hattori N., and Ikebe S.I. An immunohistochemical study on αketoglutarate dehydrogenase complex in Parkinson's disease. Ann Neurol 35 (1994) 204
-
(1994)
Ann Neurol
, vol.35
, pp. 204
-
-
Mizuno, Y.1
Matsuda, S.2
Yoshino, H.3
Mori, H.4
Hattori, N.5
Ikebe, S.I.6
-
13
-
-
0027750939
-
Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes
-
Benecke R., Strumper P., and Weiss H. Electron transfer complexes I and IV of platelets are abnormal in Parkinson's disease but normal in Parkinson-plus syndromes. Brain 116 (1993) 1451
-
(1993)
Brain
, vol.116
, pp. 1451
-
-
Benecke, R.1
Strumper, P.2
Weiss, H.3
-
14
-
-
33744984830
-
Proteasomal dysfunction in sporadic Parkinson's disease
-
McNaught K.S., Jackson T., JnoBaptiste R., Kapustin A., and Olanow C.W. Proteasomal dysfunction in sporadic Parkinson's disease. Neurology 66 10 (2006) S37
-
(2006)
Neurology
, vol.66
, Issue.10
-
-
McNaught, K.S.1
Jackson, T.2
JnoBaptiste, R.3
Kapustin, A.4
Olanow, C.W.5
-
15
-
-
0020308323
-
Parkinson's disease: a disorder due to nigral glutathione deficiency?
-
Perry T., Godin D.V., and Hansen S. Parkinson's disease: a disorder due to nigral glutathione deficiency?. Neurosci Lett 33 (1982) 305
-
(1982)
Neurosci Lett
, vol.33
, pp. 305
-
-
Perry, T.1
Godin, D.V.2
Hansen, S.3
-
16
-
-
0026635461
-
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
-
Jenner P., Dexter D.T., Sian J., Schapira A.H.V., and Marsden C.D. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. Ann Neurol 32 (1992) S82
-
(1992)
Ann Neurol
, vol.32
-
-
Jenner, P.1
Dexter, D.T.2
Sian, J.3
Schapira, A.H.V.4
Marsden, C.D.5
-
17
-
-
0024557734
-
Transition metals, ferritin, glutathione and ascorbic acid in Parkinsonian brains
-
Riederer P., Sofic E., Rausch W.D., Schmidt B., Reynolds G.P., Jellinger K., et al. Transition metals, ferritin, glutathione and ascorbic acid in Parkinsonian brains. J Neurochem 52 (1989) 515
-
(1989)
J Neurochem
, vol.52
, pp. 515
-
-
Riederer, P.1
Sofic, E.2
Rausch, W.D.3
Schmidt, B.4
Reynolds, G.P.5
Jellinger, K.6
-
18
-
-
0030724621
-
Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
-
Pearce R.K.B., Owen A., Daniel S., Jenner P., and Marsden C.D. Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease. J Neural Transm 104 (1997) 661
-
(1997)
J Neural Transm
, vol.104
, pp. 661
-
-
Pearce, R.K.B.1
Owen, A.2
Daniel, S.3
Jenner, P.4
Marsden, C.D.5
-
19
-
-
0030792637
-
Multiple roles of glutathione in the central nervous system
-
Cooper A.J.L., and Kristal B.S. Multiple roles of glutathione in the central nervous system. Biol Chem 378 (2007) 793
-
(2007)
Biol Chem
, vol.378
, pp. 793
-
-
Cooper, A.J.L.1
Kristal, B.S.2
-
20
-
-
0343131929
-
Differential compartmentalization of brain ascorbate and glutathione between neurons and glia
-
Rice M.E., and Russo-Menna I. Differential compartmentalization of brain ascorbate and glutathione between neurons and glia. Neuroscience 82 4 (1998) 1213
-
(1998)
Neuroscience
, vol.82
, Issue.4
, pp. 1213
-
-
Rice, M.E.1
Russo-Menna, I.2
-
21
-
-
0026030924
-
Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-pthaldialdehyde-induced histofluorescence
-
Philbert M.A., Beiswanger C.M., Waters D.K., Reuhl K.R., and Lowndes H.E. Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-pthaldialdehyde-induced histofluorescence. Toxicol Appl Pharmacol 107 (1991) 215
-
(1991)
Toxicol Appl Pharmacol
, vol.107
, pp. 215
-
-
Philbert, M.A.1
Beiswanger, C.M.2
Waters, D.K.3
Reuhl, K.R.4
Lowndes, H.E.5
-
22
-
-
33746423234
-
Free radicals and thiol compounds - the role of glutathione against free radical toxicity
-
Vina J. (Ed), CRC Press, Boca Raton, FL, USA
-
Saez G.T., Bannister W.H., and Bannister J.V. Free radicals and thiol compounds - the role of glutathione against free radical toxicity. In: Vina J. (Ed). Glutathione: metabolism and physiological functions (1990), CRC Press, Boca Raton, FL, USA 237
-
(1990)
Glutathione: metabolism and physiological functions
, pp. 237
-
-
Saez, G.T.1
Bannister, W.H.2
Bannister, J.V.3
-
23
-
-
0028287096
-
Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediate
-
Clancy R.M., Lavartovsky D., Leszcynska-Piziak J., Yegudin J., and Abramson S.B. Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediate. Proc Natl Acad Sci U S A 91 (1994) 3680
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 3680
-
-
Clancy, R.M.1
Lavartovsky, D.2
Leszcynska-Piziak, J.3
Yegudin, J.4
Abramson, S.B.5
-
24
-
-
0028114890
-
The reactions of superoxide with reduced glutathione
-
Winterbourn C.C., and Metodiewa D. The reactions of superoxide with reduced glutathione. Arch Biochem Biophys 314 (1994) 284
-
(1994)
Arch Biochem Biophys
, vol.314
, pp. 284
-
-
Winterbourn, C.C.1
Metodiewa, D.2
-
25
-
-
0031418498
-
Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death
-
Bains J.S., and Shaw C.A. Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Rev 25 (1997) 335
-
(1997)
Brain Res Rev
, vol.25
, pp. 335
-
-
Bains, J.S.1
Shaw, C.A.2
-
26
-
-
0029949789
-
Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones
-
Wullner U., Loschmann P.A., Schulz J.B., Schmid A., Dringen R., Eblen F., et al. Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones. NeuroReport 7 (1996) 921
-
(1996)
NeuroReport
, vol.7
, pp. 921
-
-
Wullner, U.1
Loschmann, P.A.2
Schulz, J.B.3
Schmid, A.4
Dringen, R.5
Eblen, F.6
-
27
-
-
0031025395
-
Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures
-
Zeevalk G.D., Bernard L.P., Albers D.S., Mirochnitchenko O., Nicklas W.J., and Sonsalla P.K. Energy stress-induced dopamine loss in glutathione peroxidase-overexpressing transgenic mice and in glutathione-depleted mesencephalic cultures. J Neurochem 68 (1997) 426
-
(1997)
J Neurochem
, vol.68
, pp. 426
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Albers, D.S.3
Mirochnitchenko, O.4
Nicklas, W.J.5
Sonsalla, P.K.6
-
28
-
-
0031929586
-
Role of oxidative stress and the glutathione system in loss of dopamine neurons due to impairment of energy metabolism
-
Zeevalk G.D., Bernard L.P., and Nicklas W.J. Role of oxidative stress and the glutathione system in loss of dopamine neurons due to impairment of energy metabolism. J Neurochem 70 (1998) 1421
-
(1998)
J Neurochem
, vol.70
, pp. 1421
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Nicklas, W.J.3
-
29
-
-
0033993641
-
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitopropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Klivenyi P., Andreassen O.A., Ferrante R.J., Dedeoglu A., Mueller G., Lancelot E., et al. Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitopropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. J Neurosci 20 (2000) 1
-
(2000)
J Neurosci
, vol.20
, pp. 1
-
-
Klivenyi, P.1
Andreassen, O.A.2
Ferrante, R.J.3
Dedeoglu, A.4
Mueller, G.5
Lancelot, E.6
-
30
-
-
0032564134
-
Parkinson's disease, pesticides, and glutathione transferase polymorphisms
-
Menegon A., Board P.G., Blackburn A.C., Mellick G.D., and LeCouteur D.G. Parkinson's disease, pesticides, and glutathione transferase polymorphisms. Lancet 352 9137 (1998) 1344
-
(1998)
Lancet
, vol.352
, Issue.9137
, pp. 1344
-
-
Menegon, A.1
Board, P.G.2
Blackburn, A.C.3
Mellick, G.D.4
LeCouteur, D.G.5
-
31
-
-
0030744876
-
Mutation in alpha synuclein identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., et al. Mutation in alpha synuclein identified in families with Parkinson's disease. Science 276 (1997) 2045
-
(1997)
Science
, vol.276
, pp. 2045
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
-
32
-
-
34047274072
-
Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease
-
Golbe L.I., Di Iorio G., Markopoulou K., Athanassiadou A., Papapetropoulos S., Watts R.L., et al. Glutathione S-transferase polymorphisms and onset age in alpha-synuclein A53T mutant Parkinson's disease. Am J Med Gen 144 (2007) 254
-
(2007)
Am J Med Gen
, vol.144
, pp. 254
-
-
Golbe, L.I.1
Di Iorio, G.2
Markopoulou, K.3
Athanassiadou, A.4
Papapetropoulos, S.5
Watts, R.L.6
-
33
-
-
34547666858
-
S-glutathionylation in protein redox regulation
-
Dalla-Donne I., Rossi R., Giustarini D., Colombo R., and Milzani A. S-glutathionylation in protein redox regulation. Free Radic Biol Med 43 (2007) 883
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 883
-
-
Dalla-Donne, I.1
Rossi, R.2
Giustarini, D.3
Colombo, R.4
Milzani, A.5
-
34
-
-
18844400905
-
Peroxiredoxin 6, a 1-cysperoxidredoxin, functions in antioxidant defense and lung phospholipid metabolism
-
Manevich Y., and Fisher A.B. Peroxiredoxin 6, a 1-cysperoxidredoxin, functions in antioxidant defense and lung phospholipid metabolism. Free Radic Biol Med 38 (2005) 1422
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 1422
-
-
Manevich, Y.1
Fisher, A.B.2
-
36
-
-
0000326249
-
Glutathionyl specificity of thioltransferases: mechanistic and physiological implication
-
Packer L.C.E. (Ed), Marcel Decker, New York
-
Mieyal J.J., Srinivasan U., Starke D.W., Gravina S.A., and Mieyal P. Glutathionyl specificity of thioltransferases: mechanistic and physiological implication. In: Packer L.C.E. (Ed). Biothiols in health and disease (1995), Marcel Decker, New York 305
-
(1995)
Biothiols in health and disease
, pp. 305
-
-
Mieyal, J.J.1
Srinivasan, U.2
Starke, D.W.3
Gravina, S.A.4
Mieyal, P.5
-
37
-
-
0030296409
-
S-glutathiolated hepatocyte proteins and insulin disulfides as substrates for reduction by glutaredoxin, thioredoxin, protein disulfide isomerase and glutathione
-
Jung C.-H., and Thomas J.A. S-glutathiolated hepatocyte proteins and insulin disulfides as substrates for reduction by glutaredoxin, thioredoxin, protein disulfide isomerase and glutathione. Arch Biochem Biophys 335 1 (1996) 61
-
(1996)
Arch Biochem Biophys
, vol.335
, Issue.1
, pp. 61
-
-
Jung, C.-H.1
Thomas, J.A.2
-
38
-
-
0032972685
-
Rat brain thioltransferase: regional distribution, immunological characterization, and localization by fluorescent in situ hybridization
-
Balijepalli S., Tirumalai P.S., Swamy K.V., Boyd M.R., Mieyal J.J., and Ravindranath V. Rat brain thioltransferase: regional distribution, immunological characterization, and localization by fluorescent in situ hybridization. J Neurochem 72 (1999) 1170
-
(1999)
J Neurochem
, vol.72
, pp. 1170
-
-
Balijepalli, S.1
Tirumalai, P.S.2
Swamy, K.V.3
Boyd, M.R.4
Mieyal, J.J.5
Ravindranath, V.6
-
39
-
-
0036768195
-
Functional glutaredoxin [thioltransferase] activity in rat brain and liver mitochondria
-
Ehrhart J., Gluck M., Mieyal J., and Zeevalk G.D. Functional glutaredoxin [thioltransferase] activity in rat brain and liver mitochondria. Parkinsonism Relat Disord 8 6 (2002) 395
-
(2002)
Parkinsonism Relat Disord
, vol.8
, Issue.6
, pp. 395
-
-
Ehrhart, J.1
Gluck, M.2
Mieyal, J.3
Zeevalk, G.D.4
-
40
-
-
0034727890
-
Human brain thioltransferase: constitutive expression and localization by fluorescence in situ hybridization
-
Balijepalli S., Boyd M.R., and Ravindranath V. Human brain thioltransferase: constitutive expression and localization by fluorescence in situ hybridization. Brain Res 85 1-2 (2000) 123
-
(2000)
Brain Res
, vol.85
, Issue.1-2
, pp. 123
-
-
Balijepalli, S.1
Boyd, M.R.2
Ravindranath, V.3
-
41
-
-
0025082330
-
Mammalian thioltransferase [glutaredoxin] and protein disulfide isomerase have dehydroascorbate reductase activity
-
Wells W.W., Xu D.P., Yang Y., and Rocque P.A. Mammalian thioltransferase [glutaredoxin] and protein disulfide isomerase have dehydroascorbate reductase activity. J Biol Chem 265 26 (1990) 15361
-
(1990)
J Biol Chem
, vol.265
, Issue.26
, pp. 15361
-
-
Wells, W.W.1
Xu, D.P.2
Yang, Y.3
Rocque, P.A.4
-
42
-
-
0347358043
-
Thioltransferase mediated ascorbate recycling in human lens epithelial cells
-
Fernando M.R., Satake M., Monnier V.M., and Lou M.F. Thioltransferase mediated ascorbate recycling in human lens epithelial cells. Invest Ophthalmol Vis Sci 45 1 (2004) 230
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, Issue.1
, pp. 230
-
-
Fernando, M.R.1
Satake, M.2
Monnier, V.M.3
Lou, M.F.4
-
43
-
-
0034975804
-
Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures
-
Ehrhart J., and Zeevalk G.D. Hydrogen peroxide removal and glutathione mixed disulfide formation during metabolic inhibition in mesencephalic cultures. J Neurochem 77 (2001) 1496
-
(2001)
J Neurochem
, vol.77
, pp. 1496
-
-
Ehrhart, J.1
Zeevalk, G.D.2
-
44
-
-
0141767061
-
Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures
-
Ehrhart J., and Zeevalk G.D. Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures. J Neurochem 86 (2003) 1487
-
(2003)
J Neurochem
, vol.86
, pp. 1487
-
-
Ehrhart, J.1
Zeevalk, G.D.2
-
45
-
-
0037713388
-
Glutathione and ascorbate: role in protein-glutathione-mixed disulfide formation during oxidative stress and potential relevance to Parkinson's disease
-
Zeevalk G.D., Bernard L.P., and Ehrhart J. Glutathione and ascorbate: role in protein-glutathione-mixed disulfide formation during oxidative stress and potential relevance to Parkinson's disease. Ann N Y Acad Sci 991 (2003) 342
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 342
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Ehrhart, J.3
-
46
-
-
0035930608
-
Reversible glutathionylation regulates actin polymerization in A431 cells
-
Wang J., Boja E.S., Tan W.H., Tekle E., Fales H.M., English S., et al. Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem 276 (2001) 47763
-
(2001)
J Biol Chem
, vol.276
, pp. 47763
-
-
Wang, J.1
Boja, E.S.2
Tan, W.H.3
Tekle, E.4
Fales, H.M.5
English, S.6
-
47
-
-
0038015010
-
Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin [thioltransferase] - potential role in redox signal transduction
-
Starke D.W., Chock P.B., and Mieyal J.J. Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin [thioltransferase] - potential role in redox signal transduction. J Biol Chem 278 17 (2003) 14607
-
(2003)
J Biol Chem
, vol.278
, Issue.17
, pp. 14607
-
-
Starke, D.W.1
Chock, P.B.2
Mieyal, J.J.3
-
48
-
-
0345329603
-
Glutathione and signal transduction in the mammalian CNS
-
Janaky R., Ogita K., Pasqualotto B.A., Bains J.S., Oja S.S., Yondea Y., et al. Glutathione and signal transduction in the mammalian CNS. J Neurochem 73 (1999) 889
-
(1999)
J Neurochem
, vol.73
, pp. 889
-
-
Janaky, R.1
Ogita, K.2
Pasqualotto, B.A.3
Bains, J.S.4
Oja, S.S.5
Yondea, Y.6
-
49
-
-
0034672943
-
Metabolism and functions of glutathione in brain
-
Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol 62 (2000) 649
-
(2000)
Prog Neurobiol
, vol.62
, pp. 649
-
-
Dringen, R.1
-
50
-
-
0027976087
-
Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain
-
Makar T.K., Nedergaard M., Preuss A., Gelbard A.S., Perumal A.S., and Cooper A.J.L. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J Neurochem 62 (1994) 45
-
(1994)
J Neurochem
, vol.62
, pp. 45
-
-
Makar, T.K.1
Nedergaard, M.2
Preuss, A.3
Gelbard, A.S.4
Perumal, A.S.5
Cooper, A.J.L.6
-
51
-
-
0032126145
-
Expression and purification of human gamma-glutamylcysteine synthetase
-
Misra I., and Griffith O.W. Expression and purification of human gamma-glutamylcysteine synthetase. Protein Expr Purif 13 (1998) 268
-
(1998)
Protein Expr Purif
, vol.13
, pp. 268
-
-
Misra, I.1
Griffith, O.W.2
-
52
-
-
0019506537
-
Immunocytochemical localization of gamma-glutamyl transpeptidase in the rat CNS
-
Shine H.D., and Haber B. Immunocytochemical localization of gamma-glutamyl transpeptidase in the rat CNS. Brain Res 217 (1981) 339
-
(1981)
Brain Res
, vol.217
, pp. 339
-
-
Shine, H.D.1
Haber, B.2
-
53
-
-
0028982312
-
Glutathione-S-transferases and gamma-glutamyl transpeptidase in the rat nervous system: a basis for differential susceptibility to neurotoxicants
-
Philbert M.A., Beiswanger C.M., Manson M.M., Green J.A., Novak R.F., Primiano T., et al. Glutathione-S-transferases and gamma-glutamyl transpeptidase in the rat nervous system: a basis for differential susceptibility to neurotoxicants. Neurotoxicology 16 (1995) 349
-
(1995)
Neurotoxicology
, vol.16
, pp. 349
-
-
Philbert, M.A.1
Beiswanger, C.M.2
Manson, M.M.3
Green, J.A.4
Novak, R.F.5
Primiano, T.6
-
55
-
-
0033555806
-
Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione
-
Dringen R., Pfeiffer B., and Hamprecht B. Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci 19 (1999) 562
-
(1999)
J Neurosci
, vol.19
, pp. 562
-
-
Dringen, R.1
Pfeiffer, B.2
Hamprecht, B.3
-
56
-
-
0027421350
-
Maintenance of neuronal glutathione by glial cells
-
Sagara J., Miura K., and Bannai S. Maintenance of neuronal glutathione by glial cells. J Neurochem 61 (1993) 1677
-
(1993)
J Neurochem
, vol.61
, pp. 1677
-
-
Sagara, J.1
Miura, K.2
Bannai, S.3
-
57
-
-
0027489346
-
Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension
-
Sagara J., Miura K., and Bannai S. Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension. J Neurochem 61 (1993) 1667
-
(1993)
J Neurochem
, vol.61
, pp. 1667
-
-
Sagara, J.1
Miura, K.2
Bannai, S.3
-
58
-
-
0029988384
-
Glutathione efflux from cultured astrocytes
-
Sagara J., Makino N., and Bannai S. Glutathione efflux from cultured astrocytes. J Neurochem 66 (1996) 1876
-
(1996)
J Neurochem
, vol.66
, pp. 1876
-
-
Sagara, J.1
Makino, N.2
Bannai, S.3
-
59
-
-
0025360810
-
Glutathione turnover in cultured astrocytes: studies with [15N] glutamate
-
Yudkoff M., Pleasure D., Cregar L., Lin Z.-P., Nissim I., and Stern N.I. Glutathione turnover in cultured astrocytes: studies with [15N] glutamate. J Neurochem 55 (1990) 137
-
(1990)
J Neurochem
, vol.55
, pp. 137
-
-
Yudkoff, M.1
Pleasure, D.2
Cregar, L.3
Lin, Z.-P.4
Nissim, I.5
Stern, N.I.6
-
60
-
-
0031004608
-
The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture
-
Dringen R., Kranich O., and Hamprecht B. The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture. Neurochem Res 22 6 (1997) 727
-
(1997)
Neurochem Res
, vol.22
, Issue.6
, pp. 727
-
-
Dringen, R.1
Kranich, O.2
Hamprecht, B.3
-
61
-
-
0030749694
-
Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures
-
Dringen R., Kranich O., Loschmann P.A., and Hamprecht B. Use of dipeptides for the synthesis of glutathione by astroglia-rich primary cultures. J Neurochem 69 (1997) 868
-
(1997)
J Neurochem
, vol.69
, pp. 868
-
-
Dringen, R.1
Kranich, O.2
Loschmann, P.A.3
Hamprecht, B.4
-
62
-
-
0022553605
-
Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
-
Perry T.L., and Yong V.W. Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci Lett 67 (1986) 269
-
(1986)
Neurosci Lett
, vol.67
, pp. 269
-
-
Perry, T.L.1
Yong, V.W.2
-
63
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting the basal ganglia
-
Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Javoy-Agid F., et al. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting the basal ganglia. Ann Neurol 36 (1994) 348
-
(1994)
Ann Neurol
, vol.36
, pp. 348
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Agid, Y.5
Javoy-Agid, F.6
-
64
-
-
0026644192
-
Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
-
Sofic E., Lange K.W., Jellinger K., and Riederer P. Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci Lett 142 (1992) 128
-
(1992)
Neurosci Lett
, vol.142
, pp. 128
-
-
Sofic, E.1
Lange, K.W.2
Jellinger, K.3
Riederer, P.4
-
65
-
-
0028067656
-
Glutathione-related enzymes in brain in Parkinson's disease
-
Sian J., Dexter D.T., Lees A.J., Daniel S., Jenner P., and Marsden C.D. Glutathione-related enzymes in brain in Parkinson's disease. Ann Neurol 36 (1994) 356
-
(1994)
Ann Neurol
, vol.36
, pp. 356
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
Daniel, S.4
Jenner, P.5
Marsden, C.D.6
-
66
-
-
0023898945
-
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
-
Gibb W.R.G., and Lees A.J. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatr 51 6 (1988) 745
-
(1988)
J Neurol Neurosurg Psychiatr
, vol.51
, Issue.6
, pp. 745
-
-
Gibb, W.R.G.1
Lees, A.J.2
-
67
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol 53 (2003) S26
-
(2003)
Ann Neurol
, vol.53
-
-
Jenner, P.1
-
68
-
-
30044440010
-
Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation
-
Avraham E., Szargel R., Eyal A., Rott R., and Engelender S. Glycogen synthase kinase 3beta modulates synphilin-1 ubiquitylation and cellular inclusion formation by SIAH: implications for proteasomal function and Lewy body formation. J Biol Chem 280 52 (2005) 42877
-
(2005)
J Biol Chem
, vol.280
, Issue.52
, pp. 42877
-
-
Avraham, E.1
Szargel, R.2
Eyal, A.3
Rott, R.4
Engelender, S.5
-
69
-
-
0034946830
-
Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production
-
Lee M.H., Hyun D.H., Jenner P., and Halliwell B. Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production. J Neurochem 78 (2001) 32
-
(2001)
J Neurochem
, vol.78
, pp. 32
-
-
Lee, M.H.1
Hyun, D.H.2
Jenner, P.3
Halliwell, B.4
-
70
-
-
33750350994
-
The role of protein aggregates in neuronal pathology: guilty, innocent, or just trying to help?
-
Gispert-Sanchez S., and Auburger G. The role of protein aggregates in neuronal pathology: guilty, innocent, or just trying to help?. J Neural Transm Suppl 70 (2006) 111
-
(2006)
J Neural Transm Suppl
, vol.70
, pp. 111
-
-
Gispert-Sanchez, S.1
Auburger, G.2
-
71
-
-
23644461006
-
Lewy bodies in Parkinson's disease: protectors or perpetrators?
-
Harrower T.P., Michell A.W., and Barker R.A. Lewy bodies in Parkinson's disease: protectors or perpetrators?. Exp Neurol 195 1 (2005) 1
-
(2005)
Exp Neurol
, vol.195
, Issue.1
, pp. 1
-
-
Harrower, T.P.1
Michell, A.W.2
Barker, R.A.3
-
72
-
-
0026740057
-
New insights into the cause of Parkinson's disease
-
Jenner P., Schapira A.H.V., and Marsden C.D. New insights into the cause of Parkinson's disease. Neurology 42 (1992) 2241
-
(1992)
Neurology
, vol.42
, pp. 2241
-
-
Jenner, P.1
Schapira, A.H.V.2
Marsden, C.D.3
-
73
-
-
0026091344
-
Mitochondrial oxidative phosphorylation defects in Parkinson's disease
-
Shoffner J.M., Watts R.L., Juncos J.L., Torroni A., and Wallace D.C. Mitochondrial oxidative phosphorylation defects in Parkinson's disease. Ann Neurol 30 (1991) 332
-
(1991)
Ann Neurol
, vol.30
, pp. 332
-
-
Shoffner, J.M.1
Watts, R.L.2
Juncos, J.L.3
Torroni, A.4
Wallace, D.C.5
-
74
-
-
0026718086
-
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
-
Mann V.M., Cooper J.M., Krige D., Daniel S.E., Schapira A.H.V., and Marsden C.D. Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. Brain 115 (1992) 333
-
(1992)
Brain
, vol.115
, pp. 333
-
-
Mann, V.M.1
Cooper, J.M.2
Krige, D.3
Daniel, S.E.4
Schapira, A.H.V.5
Marsden, C.D.6
-
75
-
-
0025831821
-
Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease
-
Bindoff L.A., Birch-Machin M.A., Cartidge N.E.F., Parker W.D., and Turnbull D.M. Respiratory chain abnormalities in skeletal muscle from patients with Parkinson's disease. J Neurol Sci 104 (1991) 203
-
(1991)
J Neurol Sci
, vol.104
, pp. 203
-
-
Bindoff, L.A.1
Birch-Machin, M.A.2
Cartidge, N.E.F.3
Parker, W.D.4
Turnbull, D.M.5
-
76
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ reductase (complexI) deficiency in Parkinson's disease
-
Schapira A.H.V., Mann V.M., Cooper J.M., Dexter D., Daniel S.E., Jenner P., et al. Anatomic and disease specificity of NADH CoQ reductase (complexI) deficiency in Parkinson's disease. J Neurochem 55 (1990) 2142
-
(1990)
J Neurochem
, vol.55
, pp. 2142
-
-
Schapira, A.H.V.1
Mann, V.M.2
Cooper, J.M.3
Dexter, D.4
Daniel, S.E.5
Jenner, P.6
-
77
-
-
33749047253
-
Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease
-
Chinta S.J., and Andersen J.K. Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease. Free Radic Biol Med 41 9 (2006) 1442
-
(2006)
Free Radic Biol Med
, vol.41
, Issue.9
, pp. 1442
-
-
Chinta, S.J.1
Andersen, J.K.2
-
78
-
-
33644688266
-
Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons
-
Vesce S., Jekabsons M.B., Johnson-Cadwell L.I., and Nicholls D.G. Acute glutathione depletion restricts mitochondrial ATP export in cerebellar granule neurons. J Biol Chem 280 46 (2005) 38720
-
(2005)
J Biol Chem
, vol.280
, Issue.46
, pp. 38720
-
-
Vesce, S.1
Jekabsons, M.B.2
Johnson-Cadwell, L.I.3
Nicholls, D.G.4
-
79
-
-
0033952292
-
Enhancement of dopaminergic neurotoxicity by the mercapturate of dopamine: relevance to Parkinson's disease
-
Zhang J., Kravtsov V., Amarnath V., Picklo M.J., Graham D.G., and Montine T.J. Enhancement of dopaminergic neurotoxicity by the mercapturate of dopamine: relevance to Parkinson's disease. J Neurochem 74 (2000) 970
-
(2000)
J Neurochem
, vol.74
, pp. 970
-
-
Zhang, J.1
Kravtsov, V.2
Amarnath, V.3
Picklo, M.J.4
Graham, D.G.5
Montine, T.J.6
-
80
-
-
0022503139
-
Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium
-
Vyas I., Heikkila R.E., and Nicklas W.J. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium. J Neurochem 46 (1986) 1501
-
(1986)
J Neurochem
, vol.46
, pp. 1501
-
-
Vyas, I.1
Heikkila, R.E.2
Nicklas, W.J.3
-
81
-
-
0345438935
-
Do glutathione and ascorbic acid play a role in the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?
-
Riederer P., Strolin B.M., Dostert P., Sofic E., Heusch-neider G., and Guffroy D. Do glutathione and ascorbic acid play a role in the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?. Pharmacol Toxicol 60 S1 (1987) 39
-
(1987)
Pharmacol Toxicol
, vol.60
, Issue.SUPPL.1
, pp. 39
-
-
Riederer, P.1
Strolin, B.M.2
Dostert, P.3
Sofic, E.4
Heusch-neider, G.5
Guffroy, D.6
-
82
-
-
0031008555
-
The effects of oxidative stress on in vivo brain GSH turnover in young and mature mice
-
Chang M.L., Klaidman L.K., and Adams Jr. J.D. The effects of oxidative stress on in vivo brain GSH turnover in young and mature mice. Mol Chem Neuropathol 30 3 (1997) 187
-
(1997)
Mol Chem Neuropathol
, vol.30
, Issue.3
, pp. 187
-
-
Chang, M.L.1
Klaidman, L.K.2
Adams Jr., J.D.3
-
83
-
-
0024446756
-
Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a B-carbolinium analog of n-methyl-4-phenylpyridinium ion
-
[MPP+]
-
Neafsey E.J., Drucker G., Raikoff K., and Collins M.A. Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a B-carbolinium analog of n-methyl-4-phenylpyridinium ion. [MPP+]. Neurosci Lett 105 (1989) 344
-
(1989)
Neurosci Lett
, vol.105
, pp. 344
-
-
Neafsey, E.J.1
Drucker, G.2
Raikoff, K.3
Collins, M.A.4
-
84
-
-
0021992979
-
B-carboline analogues of n-methyl-4-phenyl-1,2,5,6-tetrahydropyridine [MPTP]: endogenous factors underlying idiopathic parkinsonism?
-
Collins M.A., and Neafsey E.J. B-carboline analogues of n-methyl-4-phenyl-1,2,5,6-tetrahydropyridine [MPTP]: endogenous factors underlying idiopathic parkinsonism?. Neurosci Lett 55 (1985) 179
-
(1985)
Neurosci Lett
, vol.55
, pp. 179
-
-
Collins, M.A.1
Neafsey, E.J.2
-
85
-
-
0023148530
-
4-Phenylpyridine and three other analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: lack of dopaminergic nigrostriatal neurotoxicity in mice and marmosets
-
Perry T.L., Jone K., Hansen S., and Wall R.A. 4-Phenylpyridine and three other analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: lack of dopaminergic nigrostriatal neurotoxicity in mice and marmosets. Neurosci Lett 75 (1987) 65
-
(1987)
Neurosci Lett
, vol.75
, pp. 65
-
-
Perry, T.L.1
Jone, K.2
Hansen, S.3
Wall, R.A.4
-
86
-
-
0029759598
-
Reactive dopamine metabolites and neurotoxicity: implications for Parkinson's disease
-
Hastings T.G., Lewis D.A., and Zigmond M.J. Reactive dopamine metabolites and neurotoxicity: implications for Parkinson's disease. Adv Exp Med Biol 387 (1996) 97
-
(1996)
Adv Exp Med Biol
, vol.387
, pp. 97
-
-
Hastings, T.G.1
Lewis, D.A.2
Zigmond, M.J.3
-
87
-
-
0034026634
-
Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures
-
Moy L.Y., Zeevalk G.D., and Sonsalla P.K. Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. J Neurochem 74 (2000) 1656
-
(2000)
J Neurochem
, vol.74
, pp. 1656
-
-
Moy, L.Y.1
Zeevalk, G.D.2
Sonsalla, P.K.3
-
88
-
-
0018095085
-
Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
-
Graham D.G. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol Pharmacol 14 (1978) 633
-
(1978)
Mol Pharmacol
, vol.14
, pp. 633
-
-
Graham, D.G.1
-
89
-
-
0028215392
-
Effects of l-cysteine on the oxidation chemistry of dopamine: new reaction pathways of potential relevance to idiopathic Parkinson's disease
-
Zhang F., and Dryhurst G. Effects of l-cysteine on the oxidation chemistry of dopamine: new reaction pathways of potential relevance to idiopathic Parkinson's disease. J Med Chem 37 8 (1994) 1084
-
(1994)
J Med Chem
, vol.37
, Issue.8
, pp. 1084
-
-
Zhang, F.1
Dryhurst, G.2
-
90
-
-
0031722906
-
Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species
-
Spencer P.E., Jenner P., Daniel S.E., Lees A.J., Marsden C.D., and Halliwell B. Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species. J Neurochem 71 (1998) 2112
-
(1998)
J Neurochem
, vol.71
, pp. 2112
-
-
Spencer, P.E.1
Jenner, P.2
Daniel, S.E.3
Lees, A.J.4
Marsden, C.D.5
Halliwell, B.6
-
91
-
-
0026164647
-
Catechol metabolites in the cerebrospinal fluid as possible markers in the early diagnosis of Parkinson's disease
-
Carlsson A., and Fornstedt B. Catechol metabolites in the cerebrospinal fluid as possible markers in the early diagnosis of Parkinson's disease. Neurology 41 5 (1991) 50
-
(1991)
Neurology
, vol.41
, Issue.5
, pp. 50
-
-
Carlsson, A.1
Fornstedt, B.2
-
92
-
-
0029878379
-
Elevated 5-S-cysteinyldopamine/homovanillic acid ratio and reduced homovanillic acid in cerebrospinal fluid: possible markers for and potential insights into the pathoetiology of Parkinson's disease
-
Cheng F.C., Kuo J.S., Chia L.G., and Dryhurst G. Elevated 5-S-cysteinyldopamine/homovanillic acid ratio and reduced homovanillic acid in cerebrospinal fluid: possible markers for and potential insights into the pathoetiology of Parkinson's disease. J Neural Transm 103 4 (1996) 433
-
(1996)
J Neural Transm
, vol.103
, Issue.4
, pp. 433
-
-
Cheng, F.C.1
Kuo, J.S.2
Chia, L.G.3
Dryhurst, G.4
-
93
-
-
0031038440
-
Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid
-
Skaper S.D., Fabris M., Ferrari V., Dalle Carbonare M., and Leon A. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid. Free Radic Biol Med 22 4 (1997) 669
-
(1997)
Free Radic Biol Med
, vol.22
, Issue.4
, pp. 669
-
-
Skaper, S.D.1
Fabris, M.2
Ferrari, V.3
Dalle Carbonare, M.4
Leon, A.5
-
95
-
-
34250804439
-
Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death
-
Papa L., Gomes E., and Rockwell P. Reactive oxygen species induced by proteasome inhibition in neuronal cells mediate mitochondrial dysfunction and a caspase-independent cell death. Apoptosis 12 8 (2007) 1389
-
(2007)
Apoptosis
, vol.12
, Issue.8
, pp. 1389
-
-
Papa, L.1
Gomes, E.2
Rockwell, P.3
-
96
-
-
33947517977
-
Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease
-
Yamamoto N., Sawada H., Izumi Y., Kumd T., Katsuki H., Shimohama S., et al. Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease. J Biol Chem 282 (2007) 4364
-
(2007)
J Biol Chem
, vol.282
, pp. 4364
-
-
Yamamoto, N.1
Sawada, H.2
Izumi, Y.3
Kumd, T.4
Katsuki, H.5
Shimohama, S.6
-
97
-
-
22044436635
-
Glutathione depletion in a midbrain-derived immortalized dopaminergic cell line results in limited tyrosine nitration of mitochondrial complex I subunits: implications for Parkinson's disease
-
Bharath S., and Andersen J.K. Glutathione depletion in a midbrain-derived immortalized dopaminergic cell line results in limited tyrosine nitration of mitochondrial complex I subunits: implications for Parkinson's disease. Antioxid Redox Signal 7 7-8 (2005) 900
-
(2005)
Antioxid Redox Signal
, vol.7
, Issue.7-8
, pp. 900
-
-
Bharath, S.1
Andersen, J.K.2
-
98
-
-
0033948161
-
Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recovery
-
Gupta A., Gupta A., Datta M., and Shukla G.S. Cerebral antioxidant status and free radical generation following glutathione depletion and subsequent recovery. Mol Cell Biochem 209 1-2 (2000) 55
-
(2000)
Mol Cell Biochem
, vol.209
, Issue.1-2
, pp. 55
-
-
Gupta, A.1
Gupta, A.2
Datta, M.3
Shukla, G.S.4
-
99
-
-
17444419341
-
Role of glutathione transport processes in kidney function
-
Lash L.H. Role of glutathione transport processes in kidney function. Toxicol Appl Pharmacol 204 3 (2005) 329
-
(2005)
Toxicol Appl Pharmacol
, vol.204
, Issue.3
, pp. 329
-
-
Lash, L.H.1
-
100
-
-
0009538631
-
-
Dolphin D., Poulson R., and Avramovic O. (Eds), Wiley, New York
-
In: Dolphin D., Poulson R., and Avramovic O. (Eds). Glutathione: chemical, biochemical and medical aspects (1989), Wiley, New York 22
-
(1989)
Glutathione: chemical, biochemical and medical aspects
, pp. 22
-
-
-
101
-
-
33846418007
-
Characterization of intracellular elevation of glutathione [GSH] with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease
-
Zeevalk G.D., Manzino L., Sonsalla P.K., and Bernard L.P. Characterization of intracellular elevation of glutathione [GSH] with glutathione monoethyl ester and GSH in brain and neuronal cultures: relevance to Parkinson's disease. Exp Neurol 203 2 (2007) 512
-
(2007)
Exp Neurol
, vol.203
, Issue.2
, pp. 512
-
-
Zeevalk, G.D.1
Manzino, L.2
Sonsalla, P.K.3
Bernard, L.P.4
-
102
-
-
0025303448
-
Evidence for carrier-mediated transport of glutathione across the blood brain barrier in the rat
-
Kannan R., Kuhlenkamp J.F., Jeandidler E., Trinh H., Ookhtens M., and Kkaplowitz N. Evidence for carrier-mediated transport of glutathione across the blood brain barrier in the rat. J Clin Invest 85 (1990) 2009
-
(1990)
J Clin Invest
, vol.85
, pp. 2009
-
-
Kannan, R.1
Kuhlenkamp, J.F.2
Jeandidler, E.3
Trinh, H.4
Ookhtens, M.5
Kkaplowitz, N.6
-
103
-
-
0018175411
-
Blood-brain barrier restriction of peptides and the low uptake of enkephalins
-
Cornford E.M., Braun L.D., Crane P.D., and Oldendorf W.H. Blood-brain barrier restriction of peptides and the low uptake of enkephalins. Endocrinology 103 4 (1978) 1297
-
(1978)
Endocrinology
, vol.103
, Issue.4
, pp. 1297
-
-
Cornford, E.M.1
Braun, L.D.2
Crane, P.D.3
Oldendorf, W.H.4
-
104
-
-
0026665103
-
Increase in rat-brain glutathione following intracerebroventricular administration of gamma-glutamylcysteine
-
Pileblad E., and Magnusson T. Increase in rat-brain glutathione following intracerebroventricular administration of gamma-glutamylcysteine. Biochem Pharmacol 44 5 (1992) 895
-
(1992)
Biochem Pharmacol
, vol.44
, Issue.5
, pp. 895
-
-
Pileblad, E.1
Magnusson, T.2
-
105
-
-
0031957160
-
Effects of reduced glutathione and N-acetylcysteine on likocaine metabolism in cimetidine treated rats
-
Testa R., Ghia M., Mattioli F., Borzone S., Caglieris S., Mereto E., et al. Effects of reduced glutathione and N-acetylcysteine on likocaine metabolism in cimetidine treated rats. Fund & Clin Pharmacol 12 (1998) 220
-
(1998)
Fund & Clin Pharmacol
, vol.12
, pp. 220
-
-
Testa, R.1
Ghia, M.2
Mattioli, F.3
Borzone, S.4
Caglieris, S.5
Mereto, E.6
-
106
-
-
0030902329
-
Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro
-
Gillissen A., Joworska M., Orth M., Coffiner M., Maes P., App E.M., et al. Nacystelyn, a novel lysine salt of N-acetylcysteine, to augment cellular antioxidant defence in vitro. Respiratory Medicine 91 (2006) 159
-
(2006)
Respiratory Medicine
, vol.91
, pp. 159
-
-
Gillissen, A.1
Joworska, M.2
Orth, M.3
Coffiner, M.4
Maes, P.5
App, E.M.6
-
107
-
-
0034988283
-
Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease
-
Pocernich C.B., Cardin A.L., Racine C.L., Lauderback C.M., and Butterfield D.A. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease. Neurochem Int 39 (2001) 141
-
(2001)
Neurochem Int
, vol.39
, pp. 141
-
-
Pocernich, C.B.1
Cardin, A.L.2
Racine, C.L.3
Lauderback, C.M.4
Butterfield, D.A.5
-
108
-
-
0033967664
-
In vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain
-
Pocernich C.B., LaFontaine M., and Butterfield D.A. In vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain. Neurochem Int 36 (2000) 185
-
(2000)
Neurochem Int
, vol.36
, pp. 185
-
-
Pocernich, C.B.1
LaFontaine, M.2
Butterfield, D.A.3
-
109
-
-
0029154990
-
Uptake and distribution of N-acetylcysteine in mice: tissue specific effects on glutathione concentrations
-
McLellan L., Lewis A.D., Hall D.J., Ansell J.D., and Wolf C.R. Uptake and distribution of N-acetylcysteine in mice: tissue specific effects on glutathione concentrations. Carcinogenesis 16 (1995) 2099
-
(1995)
Carcinogenesis
, vol.16
, pp. 2099
-
-
McLellan, L.1
Lewis, A.D.2
Hall, D.J.3
Ansell, J.D.4
Wolf, C.R.5
-
110
-
-
0019454465
-
Cysteine and cystine transport at the blood-brain barrier
-
Wade L.A., and Brady H.M. Cysteine and cystine transport at the blood-brain barrier. J Neurochem 37 (1981) 730
-
(1981)
J Neurochem
, vol.37
, pp. 730
-
-
Wade, L.A.1
Brady, H.M.2
-
111
-
-
0025299455
-
l-cysteine, a bicarbonate-sensitive endogenous excitotoxin
-
Olney J.W., Zorumski C., Price M.T., and Labruyere J. l-cysteine, a bicarbonate-sensitive endogenous excitotoxin. Science 248 4955 (1990) 596
-
(1990)
Science
, vol.248
, Issue.4955
, pp. 596
-
-
Olney, J.W.1
Zorumski, C.2
Price, M.T.3
Labruyere, J.4
-
112
-
-
0029562683
-
Neurotoxicity of cysteine: interaction with glutamate
-
Puka-Sundvall M., Eriksson P., Nilsson M., Sandberg M., and Lehmann A. Neurotoxicity of cysteine: interaction with glutamate. Brain Res 705 1-2 (1995) 65
-
(1995)
Brain Res
, vol.705
, Issue.1-2
, pp. 65
-
-
Puka-Sundvall, M.1
Eriksson, P.2
Nilsson, M.3
Sandberg, M.4
Lehmann, A.5
-
113
-
-
2342522756
-
Systemic administration of N-acetylcysteine protects dopaminergic neurons against 6-hydroxydopamine-induced degeneration
-
Munoz A.M., Rey P., Soto-Otero R., Guerra M.J., and Labandeira-Garcia J.L. Systemic administration of N-acetylcysteine protects dopaminergic neurons against 6-hydroxydopamine-induced degeneration. J Neurosci Res 76 4 (2004) 551
-
(2004)
J Neurosci Res
, vol.76
, Issue.4
, pp. 551
-
-
Munoz, A.M.1
Rey, P.2
Soto-Otero, R.3
Guerra, M.J.4
Labandeira-Garcia, J.L.5
-
114
-
-
0010478667
-
Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester
-
Martensson J., and Meister A. Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester. Proc Natl Acad Sci U S A 86 (1989) 471
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 471
-
-
Martensson, J.1
Meister, A.2
-
115
-
-
0141991150
-
Glutathione monoethylester prevents mitochondrial glutathione depletion during focal cerebral ischemia
-
Anderson M.F., Nilsson M., and Sims N.R. Glutathione monoethylester prevents mitochondrial glutathione depletion during focal cerebral ischemia. Neurochem Int 44 3 (2004) 153
-
(2004)
Neurochem Int
, vol.44
, Issue.3
, pp. 153
-
-
Anderson, M.F.1
Nilsson, M.2
Sims, N.R.3
-
116
-
-
0036313070
-
The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions
-
Anderson M.F., and Sims N.R. The effects of focal ischemia and reperfusion on the glutathione content of mitochondria from rat brain subregions. J Neurochem 81 (2002) 541
-
(2002)
J Neurochem
, vol.81
, pp. 541
-
-
Anderson, M.F.1
Sims, N.R.2
-
117
-
-
0026636491
-
A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease
-
Fahn S. A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease. Ann Neurol 32 Suppl (1992) S128
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL
-
-
Fahn, S.1
-
118
-
-
0031711714
-
DATATOP: a decade of neuroprotective inquiry. Parkinson study group. Deprenyl and tocopherol antioxidative therapy of Parkinsonism
-
Shoulson I. DATATOP: a decade of neuroprotective inquiry. Parkinson study group. Deprenyl and tocopherol antioxidative therapy of Parkinsonism. Ann Neurol 44 3 Suppl 1 (1998) S160
-
(1998)
Ann Neurol
, vol.44
, Issue.3 SUPPL. 1
-
-
Shoulson, I.1
-
119
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
Shults C.W., Haas R.H., Passov D., and Beal M.F. Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol 42 (1997) 261
-
(1997)
Ann Neurol
, vol.42
, pp. 261
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
120
-
-
34447252358
-
Randomized double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease
-
Storch A., Jost W.H., Vieregge P., Spiegel J., Greulich W., Durner J., et al. Randomized double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease. Arch Neurol 64 (2007) 938
-
(2007)
Arch Neurol
, vol.64
, pp. 938
-
-
Storch, A.1
Jost, W.H.2
Vieregge, P.3
Spiegel, J.4
Greulich, W.5
Durner, J.6
-
121
-
-
0030273666
-
Reduced intravenous glutathione in the treatment of early Parkinson's disease
-
Sechi G., Deledda M.G., Bua G., Satta W.M., Deiana G.A., Pes G.M., et al. Reduced intravenous glutathione in the treatment of early Parkinson's disease. Prog Neuro-Psychopharmacol Biol Psychiat 20 (1996) 1159
-
(1996)
Prog Neuro-Psychopharmacol Biol Psychiat
, vol.20
, pp. 1159
-
-
Sechi, G.1
Deledda, M.G.2
Bua, G.3
Satta, W.M.4
Deiana, G.A.5
Pes, G.M.6
-
122
-
-
0021705485
-
Human plasma glutathione oxidation in normal and pathological conditions
-
Magnani M., Novelli G., and Palloni R. Human plasma glutathione oxidation in normal and pathological conditions. Clin Physiol Biochem 2 (1984) 287
-
(1984)
Clin Physiol Biochem
, vol.2
, pp. 287
-
-
Magnani, M.1
Novelli, G.2
Palloni, R.3
-
123
-
-
34250683023
-
Safety and tolerability of gene therapy with an adeno-associated virus (AVV) borne GAD gene for Parkinson's disease: an open label, phase I trial
-
Kaplitt M.G., Feigin A., Tang C., Fitzsimons H.L., Mattis P., Lawlor P.A., et al. Safety and tolerability of gene therapy with an adeno-associated virus (AVV) borne GAD gene for Parkinson's disease: an open label, phase I trial. Lancet 369 (2007) 2097
-
(2007)
Lancet
, vol.369
, pp. 2097
-
-
Kaplitt, M.G.1
Feigin, A.2
Tang, C.3
Fitzsimons, H.L.4
Mattis, P.5
Lawlor, P.A.6
-
124
-
-
0032973861
-
Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis
-
Iwata-Ichikawa E., Kondo Y., Miyazaki I., Asanuma M., and Ogawa N. Glial cells protect neurons against oxidative stress via transcriptional up-regulation of the glutathione synthesis. J Neurochem 72 6 (1999) 2334
-
(1999)
J Neurochem
, vol.72
, Issue.6
, pp. 2334
-
-
Iwata-Ichikawa, E.1
Kondo, Y.2
Miyazaki, I.3
Asanuma, M.4
Ogawa, N.5
-
125
-
-
0037996661
-
Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
-
Shih A.Y., Johnson D.A., Wong G., Kraft A.D., Jiang L., Erb H., et al. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J Neurosci 23 (2003) 3394
-
(2003)
J Neurosci
, vol.23
, pp. 3394
-
-
Shih, A.Y.1
Johnson, D.A.2
Wong, G.3
Kraft, A.D.4
Jiang, L.5
Erb, H.6
-
126
-
-
33750017152
-
Enhanced biosynthesis of glutathione in the spiral ganglion of the cochlea after in vivo treatment with dexamethasone in mice
-
Nagashima R., and Ogita K. Enhanced biosynthesis of glutathione in the spiral ganglion of the cochlea after in vivo treatment with dexamethasone in mice. Brain Res 1117 1 (2006) 101
-
(2006)
Brain Res
, vol.1117
, Issue.1
, pp. 101
-
-
Nagashima, R.1
Ogita, K.2
-
127
-
-
0032931535
-
Potentiation of excitotoxic injury by high concentrations of extracellular reduced glutathione
-
Regan R.F., and Guo Y.P. Potentiation of excitotoxic injury by high concentrations of extracellular reduced glutathione. Neuroscience 91 2 (1999) 463
-
(1999)
Neuroscience
, vol.91
, Issue.2
, pp. 463
-
-
Regan, R.F.1
Guo, Y.P.2
-
128
-
-
0033616356
-
Extracellular reduced glutathione increases neuronal vulnerability to combined chemical hypoxia and glucose deprivation
-
Regan R., and Guo Y. Extracellular reduced glutathione increases neuronal vulnerability to combined chemical hypoxia and glucose deprivation. Brain Res 817 (1999) 145
-
(1999)
Brain Res
, vol.817
, pp. 145
-
-
Regan, R.1
Guo, Y.2
-
129
-
-
0031865773
-
The peptide transporter PepT2 mediates the uptake of the glutathione precursor CysGly in astroglia-rich primary cultures
-
Dringen R., Hamprecht B., and Broer S. The peptide transporter PepT2 mediates the uptake of the glutathione precursor CysGly in astroglia-rich primary cultures. J Neurochem 71 (1998) 388
-
(1998)
J Neurochem
, vol.71
, pp. 388
-
-
Dringen, R.1
Hamprecht, B.2
Broer, S.3
-
130
-
-
0032889671
-
The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative B-Ala-Lys-N-AMCA in astrocytes
-
Tom Dieck S., Heuer H., Ehrchen J., Otto C., and Bauer K. The peptide transporter PepT2 is expressed in rat brain and mediates the accumulation of the fluorescent dipeptide derivative B-Ala-Lys-N-AMCA in astrocytes. Glia 25 (1999) 10
-
(1999)
Glia
, vol.25
, pp. 10
-
-
Tom Dieck, S.1
Heuer, H.2
Ehrchen, J.3
Otto, C.4
Bauer, K.5
-
131
-
-
0029965218
-
Glutamate and cysteinylglycine effects on NMDA receptors: inhibition by ethanol
-
Morris J., and Leslie S.W. Glutamate and cysteinylglycine effects on NMDA receptors: inhibition by ethanol. Alcohol 13 2 (1996) 157
-
(1996)
Alcohol
, vol.13
, Issue.2
, pp. 157
-
-
Morris, J.1
Leslie, S.W.2
-
132
-
-
0037215549
-
Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide
-
Zhao K., Luo G., Zhao G.-M., Schiller P.W., and Szeto H.H. Transcellular transport of a highly polar 3+ net charge opioid tetrapeptide. J Pharmacol Exp Ther 304 1 (2003) 425
-
(2003)
J Pharmacol Exp Ther
, vol.304
, Issue.1
, pp. 425
-
-
Zhao, K.1
Luo, G.2
Zhao, G.-M.3
Schiller, P.W.4
Szeto, H.H.5
-
133
-
-
0035937595
-
Nanoparticulate systems for brain delivery of drugs
-
Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv Drug Deliv Rev 47 (2001) 65
-
(2001)
Adv Drug Deliv Rev
, vol.47
, pp. 65
-
-
Kreuter, J.1
-
134
-
-
0031765572
-
Nanoparticle technology for delivery of drugs across the blood-brain barrier
-
Schroeder U., Sommerfeld P., Ulrich S., and Sabel B.A. Nanoparticle technology for delivery of drugs across the blood-brain barrier. J Pharm Sci 87 (1998) 1305
-
(1998)
J Pharm Sci
, vol.87
, pp. 1305
-
-
Schroeder, U.1
Sommerfeld, P.2
Ulrich, S.3
Sabel, B.A.4
-
135
-
-
0028911362
-
Passage of peptides through the blood-brain barrier with colloidal polymer particles
-
[nanoparticles]
-
Kreuter J., Alyautdin R.N., Kharkevich D.A., and Ivanov A.A. Passage of peptides through the blood-brain barrier with colloidal polymer particles. [nanoparticles]. Brain Res 674 (1995) 171
-
(1995)
Brain Res
, vol.674
, pp. 171
-
-
Kreuter, J.1
Alyautdin, R.N.2
Kharkevich, D.A.3
Ivanov, A.A.4
-
136
-
-
0029550090
-
Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade
-
Zeevalk G.D., Derr-Yellin E., and Nicklas W.J. Relative vulnerability of dopamine and GABA neurons in mesencephalic culture to inhibition of succinate dehydrogenase by malonate and 3-nitropropionic acid and protection by NMDA receptor blockade. J Pharmacol Exp Ther 275 (1995) 1124
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1124
-
-
Zeevalk, G.D.1
Derr-Yellin, E.2
Nicklas, W.J.3
-
137
-
-
0033970161
-
Oxidative stress during energy impairment in mesencephalic cultures is not a downstream consequence of a secondary excitotoxicity
-
Zeevalk G.D., Bernard L.P., and Nicklas W.J. Oxidative stress during energy impairment in mesencephalic cultures is not a downstream consequence of a secondary excitotoxicity. Neuroscience 96 2 (2000) 309
-
(2000)
Neuroscience
, vol.96
, Issue.2
, pp. 309
-
-
Zeevalk, G.D.1
Bernard, L.P.2
Nicklas, W.J.3
|