-
1
-
-
0037124036
-
NEMO trimerizes through its coiled-coil C-terminal domain
-
Agou F., Ye F., Goffinont S., Courtois G., Yamaoka S., Israel A., and Veron M. NEMO trimerizes through its coiled-coil C-terminal domain. J. Biol. Chem. 277 (2002) 17464-17475
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 17464-17475
-
-
Agou, F.1
Ye, F.2
Goffinont, S.3
Courtois, G.4
Yamaoka, S.5
Israel, A.6
Veron, M.7
-
2
-
-
33644757144
-
Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR
-
Bax A., Griffey R.H., and Hawkins B.L. Correlation of proton and nitrogen-15 chemical shifts by multiple quantum NMR. J. Magn. Reson. 55 (1983) 301-315
-
(1983)
J. Magn. Reson.
, vol.55
, pp. 301-315
-
-
Bax, A.1
Griffey, R.H.2
Hawkins, B.L.3
-
3
-
-
3042716638
-
NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis
-
Biswas D.K., Shi Q., Baily S., Strickland I., Ghosh S., Pardee A.B., and Iglehart J.D. NF-κB activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc. Natl. Acad. Sci. USA 101 (2004) 10137-10142
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10137-10142
-
-
Biswas, D.K.1
Shi, Q.2
Baily, S.3
Strickland, I.4
Ghosh, S.5
Pardee, A.B.6
Iglehart, J.D.7
-
4
-
-
0032479179
-
Anatomy of hot spots in protein interfaces
-
Bogan A.A., and Thorn K.S. Anatomy of hot spots in protein interfaces. J. Mol. Biol. 280 (1998) 1-9
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 1-9
-
-
Bogan, A.A.1
Thorn, K.S.2
-
5
-
-
2342464085
-
The two NF-κB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G., and Karin M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 25 (2004) 280-288
-
(2004)
Trends Immunol.
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
7
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato J.A., Hayakawa M., Rothwarf D.M., Zandi E., and Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388 (1997) 548-554
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
8
-
-
0032430423
-
Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs
-
Fasshauer D., Sutton R.B., Brunger A.T., and Jahn R. Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs. Proc. Natl. Acad. Sci. USA 95 (1998) 15781-15786
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15781-15786
-
-
Fasshauer, D.1
Sutton, R.B.2
Brunger, A.T.3
Jahn, R.4
-
9
-
-
34247560784
-
NEMO oligomerization in the dynamic assembly of the IκB kinase core complex
-
Fontan E., Traincard F., Levy S.G., Yamaoka S., Veron M., and Agou F. NEMO oligomerization in the dynamic assembly of the IκB kinase core complex. FEBS J. 274 (2007) 2540-2551
-
(2007)
FEBS J.
, vol.274
, pp. 2540-2551
-
-
Fontan, E.1
Traincard, F.2
Levy, S.G.3
Yamaoka, S.4
Veron, M.5
Agou, F.6
-
10
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh S., and Karin M. Missing pieces in the NF-κB puzzle. Cell 109 Suppl (2002) S81-S96
-
(2002)
Cell
, vol.109
, Issue.SUPPL
-
-
Ghosh, S.1
Karin, M.2
-
11
-
-
0024046835
-
Model building of disulfide bonds in proteins with known three-dimensional structure
-
Hazes B., and Dijkstra B.W. Model building of disulfide bonds in proteins with known three-dimensional structure. Protein Eng. 2 (1988) 119-125
-
(1988)
Protein Eng.
, vol.2
, pp. 119-125
-
-
Hazes, B.1
Dijkstra, B.W.2
-
12
-
-
0019756004
-
Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques
-
Johnson M.L., Correia J.J., Yphantis D.A., and Halvorson H.R. Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques. Biophys. J. 36 (1981) 575-588
-
(1981)
Biophys. J.
, vol.36
, pp. 575-588
-
-
Johnson, M.L.1
Correia, J.J.2
Yphantis, D.A.3
Halvorson, H.R.4
-
13
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones T.A., Zou J.Y., Cowan S.W., and Kjeldgaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47 (1991) 110-119
-
(1991)
Acta Crystallogr. A
, vol.47
, pp. 110-119
-
-
Jones, T.A.1
Zou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
14
-
-
0033595893
-
How NF-κB is activated: the role of the IκB kinase (IKK) complex
-
Karin M. How NF-κB is activated: the role of the IκB kinase (IKK) complex. Oncogene 18 (1999) 6867-6874
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
15
-
-
0033996762
-
The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling
-
Karin M., and Delhase M. The IκB kinase (IKK) and NF-κB: key elements of proinflammatory signalling. Semin. Immunol. 12 (2000) 85-98
-
(2000)
Semin. Immunol.
, vol.12
, pp. 85-98
-
-
Karin, M.1
Delhase, M.2
-
16
-
-
0000243829
-
PROCHECK: a program to check the stereochemical quality of protein structures
-
Laskowski R.A., MacArthur M.W., Moss D.S., and Thornton J.M. PROCHECK: a program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26 (1993) 283-291
-
(1993)
J. Appl. Cryst.
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
17
-
-
0002498995
-
Computer-aided interpretation of sedimentation data for proteins
-
Harding S.A., Rowe A.J., and Horton J.C. (Eds), Royal Society of Chemistry, Cambridge
-
Laue T.M., Shah B.D., Ridgeway T.M., and Pelletier S.L. Computer-aided interpretation of sedimentation data for proteins. In: Harding S.A., Rowe A.J., and Horton J.C. (Eds). Analytical Ultracentrifugation in Biochemistry and Polymer Science (1992), Royal Society of Chemistry, Cambridge 63-89
-
(1992)
Analytical Ultracentrifugation in Biochemistry and Polymer Science
, pp. 63-89
-
-
Laue, T.M.1
Shah, B.D.2
Ridgeway, T.M.3
Pelletier, S.L.4
-
18
-
-
0026490256
-
Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein
-
Leahy D.J., Hendrickson W.A., Aukhil I., and Erickson H.P. Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein. Science 258 (1992) 987-991
-
(1992)
Science
, vol.258
, pp. 987-991
-
-
Leahy, D.J.1
Hendrickson, W.A.2
Aukhil, I.3
Erickson, H.P.4
-
19
-
-
0034641616
-
CIKS, a connection to IκB kinase and stress-activated protein kinase
-
Leonardi A., Chariot A., Claudio E., Cunningham K., and Siebenlist U. CIKS, a connection to IκB kinase and stress-activated protein kinase. Proc. Natl. Acad. Sci. USA 97 (2000) 10494-10499
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10494-10499
-
-
Leonardi, A.1
Chariot, A.2
Claudio, E.3
Cunningham, K.4
Siebenlist, U.5
-
20
-
-
0033634663
-
Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti
-
Makris C., Godfrey V.L., Krahn-Senftleben G., Takahashi T., Roberts J.L., Schwarz T., Feng L., Johnson R.S., and Karin M. Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti. Mol. Cell 5 (2000) 969-979
-
(2000)
Mol. Cell
, vol.5
, pp. 969-979
-
-
Makris, C.1
Godfrey, V.L.2
Krahn-Senftleben, G.3
Takahashi, T.4
Roberts, J.L.5
Schwarz, T.6
Feng, L.7
Johnson, R.S.8
Karin, M.9
-
21
-
-
33845428995
-
Dimerization of the IκB kinase-binding domain of NEMO is required for tumor necrosis factor α-induced NF-κB activity
-
Marienfeld R.B., Palkowitsch L., and Ghosh S. Dimerization of the IκB kinase-binding domain of NEMO is required for tumor necrosis factor α-induced NF-κB activity. Mol. Cell. Biol. 26 (2006) 9209-9219
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 9209-9219
-
-
Marienfeld, R.B.1
Palkowitsch, L.2
Ghosh, S.3
-
22
-
-
0034284715
-
Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex
-
May M.J., D'Acquisto F., Madge L.A., Glockner J., Pober J.S., and Ghosh S. Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex. Science 289 (2000) 1550-1554
-
(2000)
Science
, vol.289
, pp. 1550-1554
-
-
May, M.J.1
D'Acquisto, F.2
Madge, L.A.3
Glockner, J.4
Pober, J.S.5
Ghosh, S.6
-
23
-
-
0037195419
-
Characterization of the IκB-kinase NEMO binding domain
-
May M.J., Marienfeld R.B., and Ghosh S. Characterization of the IκB-kinase NEMO binding domain. J. Biol. Chem. 277 (2002) 45992-46000
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45992-46000
-
-
May, M.J.1
Marienfeld, R.B.2
Ghosh, S.3
-
24
-
-
0030685825
-
IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio F., Zhu H., Murray B.W., Shevchenko A., Bennett B.L., Li J., Young D.B., Barbosa M., Mann M., Manning A., et al. IKK-1 and IKK-2: cytokine-activated IκB kinases essential for NF-κB activation. Science 278 (1997) 860-866
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
-
26
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Carter C.W., and Sweet R.M. (Eds), Academic Press, New York
-
Otwinowski Z., and Minor W. Processing of X-ray diffraction data collected in oscillation mode. In: Carter C.W., and Sweet R.M. (Eds). Methods in Enzymology, Macromolecular Crystallography Part A (1997), Academic Press, New York 307-326
-
(1997)
Methods in Enzymology, Macromolecular Crystallography Part A
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
27
-
-
13844311014
-
NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline
-
Page R., Peti W., Wilson I.A., Stevens R.C., and Wuthrich K. NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline. Proc. Natl. Acad. Sci. USA 102 (2005) 1901-1905
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1901-1905
-
-
Page, R.1
Peti, W.2
Wilson, I.A.3
Stevens, R.C.4
Wuthrich, K.5
-
28
-
-
33646260450
-
Optimal description of a protein structure in terms of multiple groups undergoing TLS motion
-
Painter J., and Merritt E.A. Optimal description of a protein structure in terms of multiple groups undergoing TLS motion. Acta Crystallogr. D Biol. Crystallogr. 62 (2006) 439-450
-
(2006)
Acta Crystallogr. D Biol. Crystallogr.
, vol.62
, pp. 439-450
-
-
Painter, J.1
Merritt, E.A.2
-
29
-
-
33645158291
-
TLSMB web server for the generation of multi-group TLS models
-
Painter J., and Merritt E.A. TLSMB web server for the generation of multi-group TLS models. J. Appl. Cryst. 39 (2006) 109-111
-
(2006)
J. Appl. Cryst.
, vol.39
, pp. 109-111
-
-
Painter, J.1
Merritt, E.A.2
-
30
-
-
38049028109
-
Phosphorylation of serine 68 in the IκB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor-necrosis-factor-α-induced NF-κB activity
-
Palkowitsch L., Leidner J., Ghosh S., and Marienfeld R.B. Phosphorylation of serine 68 in the IκB kinase (IKK)-binding domain of NEMO interferes with the structure of the IKK complex and tumor-necrosis-factor-α-induced NF-κB activity. J. Biol. Chem. 283 (2008) 76-86
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 76-86
-
-
Palkowitsch, L.1
Leidner, J.2
Ghosh, S.3
Marienfeld, R.B.4
-
31
-
-
0030612833
-
Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
-
Pervushin K., Riek R., Wider G., and Wuthrich K. Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution. Proc. Natl. Acad. Sci. USA 94 (1997) 12366-12371
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12366-12371
-
-
Pervushin, K.1
Riek, R.2
Wider, G.3
Wuthrich, K.4
-
32
-
-
0034175632
-
Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice
-
Rudolph D., Yeh W.C., Wakeham A., Rudolph B., Nallainathan D., Potter J., Elia A.J., and Mak T.W. Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice. Genes Dev. 14 (2000) 854-862
-
(2000)
Genes Dev.
, vol.14
, pp. 854-862
-
-
Rudolph, D.1
Yeh, W.C.2
Wakeham, A.3
Rudolph, B.4
Nallainathan, D.5
Potter, J.6
Elia, A.J.7
Mak, T.W.8
-
33
-
-
0033638970
-
NEMO/IKK γ-deficient mice model incontinentia pigmenti
-
Schmidt-Supprian M., Bloch W., Courtois G., Addicks K., Israel A., Rajewsky K., and Pasparakis M. NEMO/IKK γ-deficient mice model incontinentia pigmenti. Mol. Cell 5 (2000) 981-992
-
(2000)
Mol. Cell
, vol.5
, pp. 981-992
-
-
Schmidt-Supprian, M.1
Bloch, W.2
Courtois, G.3
Addicks, K.4
Israel, A.5
Rajewsky, K.6
Pasparakis, M.7
-
34
-
-
33744948611
-
Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ
-
Schomer-Miller B., Higashimoto T., Lee Y.K., and Zandi E. Regulation of IκB kinase (IKK) complex by IKKγ-dependent phosphorylation of the T-loop and C terminus of IKKβ. J. Biol. Chem. 281 (2006) 15268-15276
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15268-15276
-
-
Schomer-Miller, B.1
Higashimoto, T.2
Lee, Y.K.3
Zandi, E.4
-
35
-
-
34247874508
-
Interleukin-1-induced NF-κB activation is NEMO-dependent but does not require IKKβ
-
Solt L.A., Madge L.A., Orange J.S., and May M.J. Interleukin-1-induced NF-κB activation is NEMO-dependent but does not require IKKβ. J. Biol. Chem. 282 (2007) 8724-8733
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8724-8733
-
-
Solt, L.A.1
Madge, L.A.2
Orange, J.S.3
May, M.J.4
-
36
-
-
70350545937
-
Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation
-
Tas S.W., Vervoordeldonk M.J., Hajji N., May M.J., Ghosh S., and Tak P.P. Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation. Arthritis Res. Ther. 8 (2006) R86
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Tas, S.W.1
Vervoordeldonk, M.J.2
Hajji, N.3
May, M.J.4
Ghosh, S.5
Tak, P.P.6
-
37
-
-
0037332580
-
Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation
-
Tegethoff S., Behlke J., and Scheidereit C. Tetrameric oligomerization of IκB kinase γ (IKKγ) is obligatory for IKK complex activity and NF-κB activation. Mol. Cell. Biol. 23 (2003) 2029-2041
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2029-2041
-
-
Tegethoff, S.1
Behlke, J.2
Scheidereit, C.3
-
39
-
-
0036672868
-
Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death
-
Thomas R.P., Farrow B.J., Kim S., May M.J., Hellmich M.R., and Evers B.M. Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death. Surgery 132 (2002) 127-134
-
(2002)
Surgery
, vol.132
, pp. 127-134
-
-
Thomas, R.P.1
Farrow, B.J.2
Kim, S.3
May, M.J.4
Hellmich, M.R.5
Evers, B.M.6
-
40
-
-
0000560808
-
MOLREP: an automated program for molecular replacement
-
Vagin A., and Teplyakov A. MOLREP: an automated program for molecular replacement. J. Appl. Cryst. 30 (1997) 1022-1025
-
(1997)
J. Appl. Cryst.
, vol.30
, pp. 1022-1025
-
-
Vagin, A.1
Teplyakov, A.2
-
41
-
-
0030987407
-
MultiCoil: a program for predicting two- and three-stranded coiled coils
-
Wolf E., Kim P.S., and Berger B. MultiCoil: a program for predicting two- and three-stranded coiled coils. Protein Sci. 6 (1997) 1179-1189
-
(1997)
Protein Sci.
, vol.6
, pp. 1179-1189
-
-
Wolf, E.1
Kim, P.S.2
Berger, B.3
-
42
-
-
0030611595
-
IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK
-
Woronicz J.D., Gao X., Cao Z., Rothe M., and Goeddel D.V. IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science 278 (1997) 866-869
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
43
-
-
0032568792
-
Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation
-
Yamaoka S., Courtois G., Bessia C., Whiteside S.T., Weil R., Agou F., Kirk H.E., Kay R.J., and Israel A. Complementation cloning of NEMO, a component of the IκB kinase complex essential for NF-κB activation. Cell 93 (1998) 1231-1240
-
(1998)
Cell
, vol.93
, pp. 1231-1240
-
-
Yamaoka, S.1
Courtois, G.2
Bessia, C.3
Whiteside, S.T.4
Weil, R.5
Agou, F.6
Kirk, H.E.7
Kay, R.J.8
Israel, A.9
-
44
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E., Rothwarf D.M., Delhase M., Hayakawa M., and Karin M. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 91 (1997) 243-252
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
45
-
-
0032575379
-
Direct phosphorylation of IκB by IKKα and IKKβ: discrimination between free and NF-κB-bound substrate
-
Zandi E., Chen Y., and Karin M. Direct phosphorylation of IκB by IKKα and IKKβ: discrimination between free and NF-κB-bound substrate. Science 281 (1998) 1360-1363
-
(1998)
Science
, vol.281
, pp. 1360-1363
-
-
Zandi, E.1
Chen, Y.2
Karin, M.3
|