Translocation of arrestin induced by human A3 adenosine receptor ligands in an engineered cell line: Comparison with G protein-dependent pathways

Pharmacological Research

Volumn 57, Issue 4, 2008, Pages 303-311

  Gao, Zhan Guo ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Adenosine; Agonists; Antagonists; Arrestin; G protein coupled receptors; Purines

Indexed keywords

1 [2 CHLORO 6[[(3 IODOPHENYL)METHYL]AMINO] 9H PURIN 9 YL] 1 DEOXY N METHYL BETA DEXTRO RIBOFURANURONAMIDE; 1,4 DIHYDRO 2 METHYL 6 PHENYL 4 (2 PHENYLETHYNYL) 3,5 PYRIDINEDICARBOXYLIC ACID 5 BENZYL 3 ETHYL ESTER; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2 CHLORO 6 N CYCLOPENTYLADENOSINE; 2 CHLORO N 6 (3 IODOBENZYL)ADENOSINE; 4 [2 CHLORO 6 [(3 CHLOROPHENYLMETHYL)AMINO]PURIN 9 YL] 1 (METHYLAMINOCARBONYL)BICYCLE[3.1.0]HEXANE 2,3 DIOL; 6 ETHYL 2 PHENYL 4 PROPYL 3 PYRIDINECARBOXYLIC ACID 5 THIOCARBOXYLIC ACID 5 ETHYL 3 PROPYL ESTER; 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 6 N [2 (3,5 DIMETHOXYPHENYL) 2 (2 METHYLPHENYL)ETHYL]ADENOSINE; 9 CHLORO 2 (2 FURYL) 5 PHENYLACETYLAMINO 1,2,4 TRIAZOLO[1,5 C]QUINAZOLINE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE RECEPTOR AFFECTING AGENT; BETA ARRESTIN; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSINE; LUF 5833; LUF 6000; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MRS 1743; MRS 1760; MRS 3558; MRS 3771; MRS 541; MRS 542; N (3,4 DICHLOROPHENYL) 2 CYCLOHEXYL 1H IMIDAZO [4,5 C]QUINOLIN 4 AMINE; N 6 (3 IODOBENZYL)ADENOSINE; NUCLEOSIDE DERIVATIVE; PERTUSSIS TOXIN; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; BIOENGINEERING; CELL ASSAY; CHO CELL; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ARRESTIN; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; PROTEIN TRANSPORT; RECEPTOR, ADENOSINE A3; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 42749095676     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2008.02.008     Document Type: Article

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