N6-Substituted adenosine derivatives: Selectivity, efficacy, and species differences at A3 adenosine receptors

Biochemical Pharmacology

Volumn 65, Issue 10, 2003, Pages 1675-1684

  Gao, Zhan Guo ^a   Blaustein, Joshua B ^a   Gross, Ariel S ^a   Melman, Neli ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Cyclic AMP; GPCR; Nucleosides; Purines; Receptor binding; Structure activity relationships

Indexed keywords

6 N [2 (3,5 DIMETHOXYPHENYL) 2 (2 METHYLPHENYL)ETHYL]ADENOSINE; ADENOSINE A3 RECEPTOR; ADENOSINE DERIVATIVE; N 6 (1 PHENYL 2 PENTYL)ADENOSINE; N 6 (1 PHENYLETHYL)ADENOSINE; N 6 (2 NORBORNYL)ADENOSINE; N 6 (3 CHLOROBENZYL)ADENOSINE; PHENYLISOPROPYLADENOSINE; UNCLASSIFIED DRUG; ADENOSINE; ADENOSINE RECEPTOR; CYCLIC AMP; DRUG DERIVATIVE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HEART PROTECTION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SPECIES DIFFERENCE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; ANIMAL; BINDING COMPETITION; CHEMISTRY; DRUG EFFECT; HAMSTER; HUMAN; METABOLISM; RAT;

ADENOSINE; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CYCLIC AMP; HUMANS; RATS; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0037716770     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00153-9     Document Type: Article

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