-
2
-
-
0033586952
-
Patients with refractory seizures
-
Devinsky O: Patients with refractory seizures. N. Engl. J. Med. 340(20), 1565-1570 (1999).
-
(1999)
N. Engl. J. Med
, vol.340
, Issue.20
, pp. 1565-1570
-
-
Devinsky, O.1
-
3
-
-
0036282946
-
The economic cost of epilepsy: A review of the literature
-
Begley CE, Beghi E: The economic cost of epilepsy: a review of the literature. Epilepsia 43(Suppl. 4), 3-9 (2002).
-
(2002)
Epilepsia
, vol.43
, Issue.SUPPL. 4
, pp. 3-9
-
-
Begley, C.E.1
Beghi, E.2
-
5
-
-
33645278654
-
Defining intractability: Comparisons among published definitions
-
Berg AT, Kelly MM: Defining intractability: comparisons among published definitions. Epilepsia 47(2), 431-436 (2006).
-
(2006)
Epilepsia
, vol.47
, Issue.2
, pp. 431-436
-
-
Berg, A.T.1
Kelly, M.M.2
-
6
-
-
30344467212
-
Molecular and cellular mechanisms of pharmacoresistance in epilepsy
-
Remy S, Beck H: Molecular and cellular mechanisms of pharmacoresistance in epilepsy, Brain 129(Pt 1). 18-35 (2006).
-
(2006)
Brain
, vol.129
, Issue.PART 1
, pp. 18-35
-
-
Remy, S.1
Beck, H.2
-
7
-
-
0031982725
-
Pharmacological insights from P-glycoprotein knockout mice
-
Schinkel AH: Pharmacological insights from P-glycoprotein knockout mice. Int. J. Clin. Pbarmacol. Ther. 36(1), 9-13 (1998).
-
(1998)
Int. J. Clin. Pbarmacol. Ther
, vol.36
, Issue.1
, pp. 9-13
-
-
Schinkel, A.H.1
-
8
-
-
0036128985
-
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
-
Loscher W, Potschka H: Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J. Pharmacol. Exp. Ther. 301(1), 7-14 (2002).
-
(2002)
J. Pharmacol. Exp. Ther
, vol.301
, Issue.1
, pp. 7-14
-
-
Loscher, W.1
Potschka, H.2
-
9
-
-
0036156280
-
Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy
-
Sisodiya SM. Lin WR, Harding BN, Squier MV, Tliorn M: Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy. Brain 125(Pt 1). 22-31 (2002).
-
(2002)
Brain
, vol.125
, Issue.PART 1
, pp. 22-31
-
-
Sisodiya, S.M.1
Lin, W.R.2
Harding, B.N.3
Squier, M.V.4
Tliorn, M.5
-
10
-
-
33846504706
-
A "silent" polymorphism in the MDR1 gene changes substrate specificity
-
Kimichi-Sarfaty C. Oh JM, Kim IW et al.: A "silent" polymorphism in the MDR1 gene changes substrate specificity. Science 315(5811). 525-528 (2007).
-
(2007)
Science
, vol.315
, Issue.5811
, pp. 525-528
-
-
Kimichi-Sarfaty, C.O.J.1
Kim, I.W.2
-
11
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1
-
Siddiqui A. Kerb R, Weale ME et al.: Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N. Engl. J. Med. 348(15), 1442-1448 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, Issue.15
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
-
12
-
-
21444449353
-
Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response
-
Hung CC, Tai JJ. Lin CJ, Lee MJ, Liou HH: Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response. Pharmacogenomics 6(4), 411-417 (2005).
-
(2005)
Pharmacogenomics
, vol.6
, Issue.4
, pp. 411-417
-
-
Hung, C.C.1
Tai, J.J.2
Lin, C.J.3
Lee, M.J.4
Liou, H.H.5
-
13
-
-
33744547260
-
Lack of association between C3435T nucleotide MDR1 genetic polymorphism and multidrug-resistant epilepsy
-
Kim DW, Kim M, Lee SK, Kang R, Lee SY: Lack of association between C3435T nucleotide MDR1 genetic polymorphism and multidrug-resistant epilepsy. Seizure 15(5), 344-347 (2006).
-
(2006)
Seizure
, vol.15
, Issue.5
, pp. 344-347
-
-
Kim, D.W.1
Kim, M.2
Lee, S.K.3
Kang, R.4
Lee, S.Y.5
-
14
-
-
30744472610
-
Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics
-
Kim YO, Kim MK, Woo YJ et al.: Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics. Seizure 15(1), 67-72 (2006).
-
(2006)
Seizure
, vol.15
, Issue.1
, pp. 67-72
-
-
Kim, Y.O.1
Kim, M.K.2
Woo, Y.J.3
-
15
-
-
33745963092
-
Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: A prospective cohort study
-
Leschziner G, Jorgensen AL, Andrew T et al.: Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study. Lancet Neurol. 5(8), 668-676 (2006).
-
(2006)
Lancet Neurol
, vol.5
, Issue.8
, pp. 668-676
-
-
Leschziner, G.1
Jorgensen, A.L.2
Andrew, T.3
-
16
-
-
33745155394
-
ABCB1 polymorphisms influence the response to antlepileptic drugs in Japanese epilepsy patients
-
Seo T, Ishitsu T, Ueda N et al.: ABCB1 polymorphisms influence the response to antlepileptic drugs in Japanese epilepsy patients. Pharmacogenomics 7(4), 551-561 (2006).
-
(2006)
Pharmacogenomics
, vol.7
, Issue.4
, pp. 551-561
-
-
Seo, T.1
Ishitsu, T.2
Ueda, N.3
-
17
-
-
18244365827
-
Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment
-
Sills GJ, Mohanraj R, Butler E et al.: Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment. Epilepsia 46(5), 643-647 (2005).
-
(2005)
Epilepsia
, vol.46
, Issue.5
, pp. 643-647
-
-
Sills, G.J.1
Mohanraj, R.2
Butler, E.3
-
18
-
-
4644230833
-
Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy
-
Tan NC, Heron SE, Scheffer IE et al.: Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy. Neurology 63(6), 1090-1092 (2004).
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1090-1092
-
-
Tan, N.C.1
Heron, S.E.2
Scheffer, I.E.3
-
19
-
-
4644305242
-
Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy
-
Zimprich F, Sunder-Plassmann R, Stogmann E et al.: Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy. Neurology 63(6), 1087-1089 (2004).
-
(2004)
Neurology
, vol.63
, Issue.6
, pp. 1087-1089
-
-
Zimprich, F.1
Sunder-Plassmann, R.2
Stogmann, E.3
-
20
-
-
33847366654
-
The controversial association of ABCB1 polymorphisms in refractory epilepsy: An analysis of multiple SNPs in an Irish population
-
Shahwan A, Murphy K, Doherty C et al.: The controversial association of ABCB1 polymorphisms in refractory epilepsy: an analysis of multiple SNPs in an Irish population. Epilepsy Res. 73(2), 192-198 (2007).
-
(2007)
Epilepsy Res
, vol.73
, Issue.2
, pp. 192-198
-
-
Shahwan, A.1
Murphy, K.2
Doherty, C.3
-
21
-
-
27644474133
-
RLIP76, a non-ABC transporter, and drug resistance in epilepsy
-
Awasthi S, Hallene KL, Fazio V et al.: RLIP76, a non-ABC transporter, and drug resistance in epilepsy. BMC Neurosci. 6, 61 (2005).
-
(2005)
BMC Neurosci
, vol.6
, pp. 61
-
-
Awasthi, S.1
Hallene, K.L.2
Fazio, V.3
-
22
-
-
34247104934
-
Lack of support for a role for RLIP76 (RALBP 1) in response to treatment or predisposition to epilepsy
-
Soranzo N, Kelly L, Martinian L et al.: Lack of support for a role for RLIP76 (RALBP 1) in response to treatment or predisposition to epilepsy. Epilepsia 48(4), 674-683 (2007).
-
(2007)
Epilepsia
, vol.48
, Issue.4
, pp. 674-683
-
-
Soranzo, N.1
Kelly, L.2
Martinian, L.3
-
23
-
-
0037328994
-
Pharmacogenetics of the major polymorphic metabolizing enzymes
-
Daly AK: Pharmacogenetics of the major polymorphic metabolizing enzymes. Fundam. Clin. Pharmacol. 17(1), 27-41 (2003).
-
(2003)
Fundam. Clin. Pharmacol
, vol.17
, Issue.1
, pp. 27-41
-
-
Daly, A.K.1
-
24
-
-
0035069775
-
Visual field defects with vigabatrin: Epidemiology and therapeutic implications
-
Kalviainen R, Nousiainen I: Visual field defects with vigabatrin: epidemiology and therapeutic implications. CNS Drugs 15(3), 217-230 (2001).
-
(2001)
CNS Drugs
, vol.15
, Issue.3
, pp. 217-230
-
-
Kalviainen, R.1
Nousiainen, I.2
-
25
-
-
0037344108
-
The effects of adjunctive topiramate on cognitive function in patients with epilepsy
-
Lee S, Sziklas V, Andermann F et al.: The effects of adjunctive topiramate on cognitive function in patients with epilepsy. Epilepsia 44(3), 339-347 (2003).
-
(2003)
Epilepsia
, vol.44
, Issue.3
, pp. 339-347
-
-
Lee, S.1
Sziklas, V.2
Andermann, F.3
-
26
-
-
0042831348
-
Screening for the potential of a drug candidate to cause idiosyncratic drug reactions
-
Uetrecht J: Screening for the potential of a drug candidate to cause idiosyncratic drug reactions. Drug Discov. Today 8(18), 832-837 (2003).
-
(2003)
Drug Discov. Today
, vol.8
, Issue.18
, pp. 832-837
-
-
Uetrecht, J.1
-
27
-
-
0035836342
-
TNFα promoter region gene polymorphisms in carbamazepine-hypersensitive patients
-
Pirmohamed M, Lin K, Chadwick D, Park BK: TNFα promoter region gene polymorphisms in carbamazepine-hypersensitive patients. Neurology 56(7), 890-896 (2001).
-
(2001)
Neurology
, vol.56
, Issue.7
, pp. 890-896
-
-
Pirmohamed, M.1
Lin, K.2
Chadwick, D.3
Park, B.K.4
-
28
-
-
34247395197
-
Medical genetics: A marker for Stevens-Johnson syndrome
-
Chung WH, Hung SI, Hong HS et al.: Medical genetics: a marker for Stevens-Johnson syndrome. Nature 428(6982), 496 (2004).
-
(2004)
Nature
, vol.428
, Issue.6982
, pp. 496
-
-
Chung, W.H.1
Hung, S.I.2
Hong, H.S.3
-
29
-
-
33645082244
-
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions
-
Hung SI, Chung WH. Jee SH et al.: Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet. Genomics 16(4). 297-306 (2006).
-
(2006)
Pharmacogenet. Genomics
, vol.16
, Issue.4
, pp. 297-306
-
-
Hung, S.I.1
Chung, W.H.2
Jee, S.H.3
-
30
-
-
34248589506
-
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese
-
Man CB, Kwan P, Baum L et al.: Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia 48(5), 1015-1018 (2007).
-
(2007)
Epilepsia
, vol.48
, Issue.5
, pp. 1015-1018
-
-
Man, C.B.1
Kwan, P.2
Baum, L.3
-
31
-
-
33646934721
-
A marker for Stevens-Johnson syndrome: Ethnicity matters
-
Lonjou C. Thomas L, Borot N et al.: A marker for Stevens-Johnson syndrome: ethnicity matters. Pharmacogenomics J. 6(4), 265-268 (2006).
-
(2006)
Pharmacogenomics J
, vol.6
, Issue.4
, pp. 265-268
-
-
Lonjou, C.1
Thomas, L.2
Borot, N.3
-
32
-
-
33748987340
-
HLA-B locus in Caucasian patients with carbamazepine. hypersensitivity
-
Alfirevic A, Jorgensen AL, Williamson PR et al.: HLA-B locus in Caucasian patients with carbamazepine. hypersensitivity. Pharmacogenomics 7(6), 813-818 (2006).
-
(2006)
Pharmacogenomics
, vol.7
, Issue.6
, pp. 813-818
-
-
Alfirevic, A.1
Jorgensen, A.L.2
Williamson, P.R.3
-
33
-
-
33645065133
-
Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster
-
20061
-
Alfirevic A. Mills T, Harrington P et al.: Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster. Pharmacogenet. Genomics 16(4), 287-296 (20061.
-
Pharmacogenet. Genomics
, vol.16
, Issue.4
, pp. 287-296
-
-
Alfirevic, A.1
Mills, T.2
Harrington, P.3
-
34
-
-
0034748878
-
Severe phenytoin Intoxication in a subject homozygous for CYP2C9*3
-
Brandolese R, Scordo MG, Spina E, Gusella M, Padrini R: Severe phenytoin Intoxication in a subject homozygous for CYP2C9*3. Clin. Pharmacol. Ther. 70(4), 391-394 (2001).
-
(2001)
Clin. Pharmacol. Ther
, vol.70
, Issue.4
, pp. 391-394
-
-
Brandolese, R.1
Scordo, M.G.2
Spina, E.3
Gusella, M.4
Padrini, R.5
-
35
-
-
0034042132
-
Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication
-
Ninomiya H, Mamiya K, Matsuo S et al.: Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication. Ther. Drug Monit. 22(2), 230-232 (2000).
-
(2000)
Ther. Drug Monit
, vol.22
, Issue.2
, pp. 230-232
-
-
Ninomiya, H.1
Mamiya, K.2
Matsuo, S.3
-
36
-
-
20244368950
-
Genetic predictor of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin
-
Tate SK, Depondt C, Sisodiya SM et al.: Genetic predictor of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc. Natl Acad. Sci. USA 102(15), 5507-5512 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.15
, pp. 5507-5512
-
-
Tate, S.K.1
Depondt, C.2
Sisodiya, S.M.3
-
37
-
-
0032819729
-
Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin
-
Aynacioglu AS, Brockmoller J, Bauer S et al.: Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin. Br. J. Clin. Pharmacol. 48(3), 409-415 (1999).
-
(1999)
Br. J. Clin. Pharmacol
, vol.48
, Issue.3
, pp. 409-415
-
-
Aynacioglu, A.S.1
Brockmoller, J.2
Bauer, S.3
-
38
-
-
4744365530
-
Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms
-
Hung CC, Lin CJ. Chen CC, Chang CJ, Liou HH: Dosage recommendation of phenytoin for patients with epilepsy with different CYP2C9/CYP2C19 polymorphisms. Ther. Drug Monit. 26(5), 534-540 (2004).
-
(2004)
Ther. Drug Monit
, vol.26
, Issue.5
, pp. 534-540
-
-
Hung, C.C.1
Lin, C.J.2
Chen, C.C.3
Chang, C.J.4
Liou, H.H.5
-
39
-
-
0032440352
-
The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: Studies in stereoselective hydroxylation and population pharmacokinetics
-
Mamiya K,Ieiri I. Shimamoto J etal.: The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics. Epilepsia 39(12), 1317-1323 (1998).
-
(1998)
Epilepsia
, vol.39
, Issue.12
, pp. 1317-1323
-
-
Mamiya, K.1
Ieiri, I.2
Shimamoto, J.3
-
40
-
-
0030858160
-
Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy
-
Odani A, Hashimoto Y, Otsuki Y et al.: Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. Clin. Phaimacol. Ther. 62(3), 287-292 (1997).
-
(1997)
Clin. Phaimacol. Ther
, vol.62
, Issue.3
, pp. 287-292
-
-
Odani, A.1
Hashimoto, Y.2
Otsuki, Y.3
-
41
-
-
0034978572
-
The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement
-
van der Weide J, Steijns LS, van Weelden MJ. de Haan K: The effect of genetic polymorphism of cytochrome P450 CYP2C9 on phenytoin dose requirement. Pharmacogenetics 11 (4), 287-291 (2001).
-
(2001)
Pharmacogenetics
, vol.11
, Issue.4
, pp. 287-291
-
-
van der Weide, J.1
Steijns, L.S.2
van Weelden, M.J.3
de Haan, K.4
-
43
-
-
33749037686
-
A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose
-
Tate SK, Singh R, Hung CC et al.: A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose. Pharmacogenet. Genomics 16(10). 721-726 (2006).
-
(2006)
Pharmacogenet. Genomics
, vol.16
, Issue.10
, pp. 721-726
-
-
Tate, S.K.1
Singh, R.2
Hung, C.C.3
-
44
-
-
34247586517
-
-
Heinzen EL, Yoon W. Tate SK et al.: Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. Am. J Hum. Genet. 80(5), 876-883 (2007).
-
Heinzen EL, Yoon W. Tate SK et al.: Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. Am. J Hum. Genet. 80(5), 876-883 (2007).
-
-
-
-
45
-
-
33746124235
-
Case-control studies in the genomic era: A clinician's guide
-
Healy DG: Case-control studies in the genomic era: a clinician's guide. Lancet Neurol. 5(8), 701-707 (2006).
-
(2006)
Lancet Neurol
, vol.5
, Issue.8
, pp. 701-707
-
-
Healy, D.G.1
-
46
-
-
34247349605
-
Nuclear receptori and the regulation of drug-metabollzing enzymes and drug transporters: Implications for interindividual variability in response to drugs
-
Urquhart BL, Tirona RG, Kim RB: Nuclear receptori and the regulation of drug-metabollzing enzymes and drug transporters: implications for interindividual variability in response to drugs. J Clin. Pharmacol. 47(5), 566-578 (2007).
-
(2007)
J Clin. Pharmacol
, vol.47
, Issue.5
, pp. 566-578
-
-
Urquhart, B.L.1
Tirona, R.G.2
Kim, R.B.3
-
47
-
-
33748950454
-
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation
-
Bauer B, Yang X, Hartz AM et al.: In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation. Mol. Pharmacol. 70(4), 1212-1219 (2006).
-
(2006)
Mol. Pharmacol
, vol.70
, Issue.4
, pp. 1212-1219
-
-
Bauer, B.1
Yang, X.2
Hartz, A.M.3
-
48
-
-
33644873796
-
-
Ouahchi K, Lindeman N. Lee C: Copy number variants and pharmacogenomics. Pharmacogenamics 7(1), 25-29 (2006).
-
Ouahchi K, Lindeman N. Lee C: Copy number variants and pharmacogenomics. Pharmacogenamics 7(1), 25-29 (2006).
-
-
-
-
49
-
-
0142134358
-
The relevance of alternative RNA splicing to pharmacogenomics
-
Bracco L, Kearsey J: The relevance of alternative RNA splicing to pharmacogenomics. Trends Biotechnol. 21(8), 346-353 (2003).
-
(2003)
Trends Biotechnol
, vol.21
, Issue.8
, pp. 346-353
-
-
Bracco, L.1
Kearsey, J.2
-
50
-
-
27744491843
-
Applications of AmpliChip CYP450
-
Jain KK: Applications of AmpliChip CYP450. Mol. Diagn. 9(3), 119-127 (2005).
-
(2005)
Mol. Diagn
, vol.9
, Issue.3
, pp. 119-127
-
-
Jain, K.K.1
-
51
-
-
31044434278
-
The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies
-
Woelderink A. Ibarreta D, Hopkins MM, Rodriguez-Cerezo E: The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies. Pharmacogenomics J. 6(1), 3-7 (2006).
-
(2006)
Pharmacogenomics J
, vol.6
, Issue.1
, pp. 3-7
-
-
Woelderink, A.1
Ibarreta, D.2
Hopkins, M.M.3
Rodriguez-Cerezo, E.4
-
52
-
-
22844448777
-
Priorities and standards in pharmacogenetic research
-
Need AC, Motulsky AG, Goldstein DB: Priorities and standards in pharmacogenetic research. Nat. Genet. 37(7), 671-681 (2005).
-
(2005)
Nat. Genet
, vol.37
, Issue.7
, pp. 671-681
-
-
Need, A.C.1
Motulsky, A.G.2
Goldstein, D.B.3
-
53
-
-
0036224915
-
Inhibitors of multidrug resistance to antitumor agents (MDR)
-
Avendano C, Menendez JC: Inhibitors of multidrug resistance to antitumor agents (MDR). Curr. Med. Chem. 9(2), 159-193 (2002).
-
(2002)
Curr. Med. Chem
, vol.9
, Issue.2
, pp. 159-193
-
-
Avendano, C.1
Menendez, J.C.2
-
54
-
-
20544434626
-
Calcium-channel blocker verapamil administration in prolonged and refractory status epilepticus
-
Iannetti P, Spatice A, Parisi P: Calcium-channel blocker verapamil administration in prolonged and refractory status epilepticus. Epilepsia 46(6), 967-969 (2005).
-
(2005)
Epilepsia
, vol.46
, Issue.6
, pp. 967-969
-
-
Iannetti, P.1
Spatice, A.2
Parisi, P.3
-
55
-
-
0036361559
-
OC144-093, a novel P glycoprotein inhibitor for the enhancement of anti-epileptic therapy
-
discussion 226-230, 231-215
-
Newman MJ, Dixon R, Toyonaga B: OC144-093, a novel P glycoprotein inhibitor for the enhancement of anti-epileptic therapy. Novartis Found. Symp. 243, 213-226; discussion 226-230, 231-215 (2002).
-
(2002)
Novartis Found. Symp
, vol.243
, pp. 213-226
-
-
Newman, M.J.1
Dixon, R.2
Toyonaga, B.3
-
56
-
-
4644269603
-
Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy
-
Summers MA, Moore JL, McAuley JW: Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy. Ann. Pharmacother. 38(10), 1631-1634 (2004).
-
(2004)
Ann. Pharmacother
, vol.38
, Issue.10
, pp. 1631-1634
-
-
Summers, M.A.1
Moore, J.L.2
McAuley, J.W.3
-
57
-
-
25644454404
-
Pharmaceuticals: A new grammar for drug discovery
-
Fishman MC, Porter JA: Pharmaceuticals: a new grammar for drug discovery. Nature 437(7058), 491-493 (2005).
-
(2005)
Nature
, vol.437
, Issue.7058
, pp. 491-493
-
-
Fishman, M.C.1
Porter, J.A.2
-
58
-
-
2642570170
-
Moving towards individualized medicine with pharmacogenomics
-
Evans WE, Relling MV: Moving towards individualized medicine with pharmacogenomics. Nature 429 (6990), 464-468 (2004).
-
(2004)
Nature
, vol.429
, Issue.6990
, pp. 464-468
-
-
Evans, W.E.1
Relling, M.V.2
-
59
-
-
4344684441
-
Pharmacogenetics and drug development: The path to safer and more effective drugs
-
Roses AD: Pharmacogenetics and drug development: the path to safer and more effective drugs. Nat. Rev. Genet. 5(9), 645-656 (2004).
-
(2004)
Nat. Rev. Genet
, vol.5
, Issue.9
, pp. 645-656
-
-
Roses, A.D.1
-
61
-
-
0036220551
-
The importance of drug interactions in epilepsy therapy
-
Patsalos PN, Froscher W, Pisani F, van Rijn CM: The importance of drug interactions in epilepsy therapy. Epileasia 43(4), 365-385 (2002).
-
(2002)
Epileasia
, vol.43
, Issue.4
, pp. 365-385
-
-
Patsalos, P.N.1
Froscher, W.2
Pisani, F.3
van Rijn, C.M.4
-
62
-
-
10044275247
-
N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7
-
Staines AG, Coughtrie MW, Burchell B: N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7. J. Pharmacol. Exp. Ther. 311(3), 1131-1137 (2004).
-
(2004)
J. Pharmacol. Exp. Ther
, vol.311
, Issue.3
, pp. 1131-1137
-
-
Staines, A.G.1
Coughtrie, M.W.2
Burchell, B.3
-
63
-
-
0034935392
-
The mechanisms of action of commonly used antiepileptic drugs
-
Kwan P, Sills GJ, Brodie MJ: The mechanisms of action of commonly used antiepileptic drugs. Pharmacol. Ther. 90(1), 21-34 (2001).
-
(2001)
Pharmacol. Ther
, vol.90
, Issue.1
, pp. 21-34
-
-
Kwan, P.1
Sills, G.J.2
Brodie, M.J.3
-
64
-
-
3042748137
-
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch BA, Lambeng N, Nocka K et al.: The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc. Natl. Acad. Sci. USA 101 (26), 9861-9866 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.26
, pp. 9861-9866
-
-
Lynch, B.A.1
Lambeng, N.2
Nocka, K.3
|