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Volumn 5, Issue 2, 2008, Pages 349-357

Biodegradable, cationic methacrylamide-based polymers for gene delivery to ovarian cancer cells in mice

Author keywords

Biodegradable; Cytotoxicity; Gene delivery; Gene therapy; Hyaluronic acid; Methacrylamide polymers; Ovarian cancer

Indexed keywords

HYALURONIC ACID; POLY[N (2 HYDROXYPROPYL)METHACRYLAMIDE]; POLYANION; POLYETHYLENEIMINE;

EID: 42549156323     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp700108r     Document Type: Article
Times cited : (19)

References (37)
  • 1
    • 18344380440 scopus 로고    scopus 로고
    • Ovarian cancer metastasis: Integrating insights from disparate model organisms
    • Naora, H.; Montell, D. J. Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat. Rev. Cancer 2005, 5 (5), 355-66.
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.5 , pp. 355-366
    • Naora, H.1    Montell, D.J.2
  • 2
    • 0027310291 scopus 로고
    • Pathogenesis of malignant ascites formation: Initiating events that lead to fluid accumulation
    • Nagy, J. A.; Herzberg, K. T.; Dvorak, J. M.; Dvorak, H. F. Pathogenesis of malignant ascites formation: initiating events that lead to fluid accumulation. Cancer Res. 1993, 53 (11), 2631-43.
    • (1993) Cancer Res , vol.53 , Issue.11 , pp. 2631-2643
    • Nagy, J.A.1    Herzberg, K.T.2    Dvorak, J.M.3    Dvorak, H.F.4
  • 3
    • 0036726589 scopus 로고    scopus 로고
    • Gene therapy for ovarian cancer (review)
    • Wolf, J. K.; Jenkins, A. D. Gene therapy for ovarian cancer (review). Int. J. Oncol. 2002, 21 (3), 461-8.
    • (2002) Int. J. Oncol , vol.21 , Issue.3 , pp. 461-468
    • Wolf, J.K.1    Jenkins, A.D.2
  • 6
    • 26444536288 scopus 로고    scopus 로고
    • Application of poly(2-(dimethylamino) ethyl methacrylate)-based polyplexes for gene transfer into human ovarian carcinoma cells
    • Verbaan, F. J.; Klouwenberg, P. K.; Van Steenis, J. H.; Snel, C. J.; Boerman, O.; Hennink, W. E.; Storm, G. Application of poly(2-(dimethylamino) ethyl methacrylate)-based polyplexes for gene transfer into human ovarian carcinoma cells. Int. J. Pharm. 2005, 304 (1-2), 185-92.
    • (2005) Int. J. Pharm , vol.304 , Issue.1-2 , pp. 185-192
    • Verbaan, F.J.1    Klouwenberg, P.K.2    Van Steenis, J.H.3    Snel, C.J.4    Boerman, O.5    Hennink, W.E.6    Storm, G.7
  • 7
    • 0021683409 scopus 로고
    • Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis in mice
    • Hamilton, T. C.; Young, R. C.; Louie, K. G.; Behrens, B. C.; Mckoy, W. M.; Grotzinger, K. R.; Ozols, R. F. Characterization of a xenograft model of human ovarian carcinoma which produces ascites and intraabdominal carcinomatosis in mice. Cancer Res. 1984, 44 (11), 5286-90.
    • (1984) Cancer Res , vol.44 , Issue.11 , pp. 5286-5290
    • Hamilton, T.C.1    Young, R.C.2    Louie, K.G.3    Behrens, B.C.4    Mckoy, W.M.5    Grotzinger, K.R.6    Ozols, R.F.7
  • 8
    • 0033122136 scopus 로고    scopus 로고
    • Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
    • Van De Wetering, P.; Schuurmans-Nieuwenbroek, N. M.; Hennink, W. E.; Storm, G. Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. J. Gene Med. 1999, 1 (3), 156-65.
    • (1999) J. Gene Med , vol.1 , Issue.3 , pp. 156-165
    • Van De Wetering, P.1    Schuurmans-Nieuwenbroek, N.M.2    Hennink, W.E.3    Storm, G.4
  • 9
    • 0030001470 scopus 로고    scopus 로고
    • Increased hyaluronan at sites of attachment to mesentery by CD44-positive mouse ovarian and breast tumor cells
    • Yeo, T. K.; Nagy, J. A.; Yeo, K. T.; Dvorak, H. F.; Toole, B. P. Increased hyaluronan at sites of attachment to mesentery by CD44-positive mouse ovarian and breast tumor cells. Am. J. Pathol. 1996, 148 (6), 1733-40.
    • (1996) Am. J. Pathol , vol.148 , Issue.6 , pp. 1733-1740
    • Yeo, T.K.1    Nagy, J.A.2    Yeo, K.T.3    Dvorak, H.F.4    Toole, B.P.5
  • 11
    • 33751404700 scopus 로고    scopus 로고
    • Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity
    • Hunter, A. C. Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity. Adv. Drug Deliv. Rev. 2006, 58 (14), 1523-31.
    • (2006) Adv. Drug Deliv. Rev , vol.58 , Issue.14 , pp. 1523-1531
    • Hunter, A.C.1
  • 12
    • 33746725941 scopus 로고    scopus 로고
    • Methacrylamide polymers with hydrolysis-sensitive cationic side groups as degradable gene carriers
    • Luten, J.; Akeroyd, N.; Funhoff, A.; Lok, M. C.; Talsma, H.; Hennink, W. E. Methacrylamide polymers with hydrolysis-sensitive cationic side groups as degradable gene carriers. Bioconjuate Chem. 2006, 17 (4), 1077-84.
    • (2006) Bioconjuate Chem , vol.17 , Issue.4 , pp. 1077-1084
    • Luten, J.1    Akeroyd, N.2    Funhoff, A.3    Lok, M.C.4    Talsma, H.5    Hennink, W.E.6
  • 13
    • 0142072936 scopus 로고    scopus 로고
    • Novel Shielded Transferrin-Polyethylene Glycol-Polyethylenimine/ DNA Complexes for Systemic Tumor-Targeted Gene Transfer
    • Kursa, M.; Walker, G. F.; Roessler, V.; Ogris, M.; Roedl, W.; Kircheis, R.; Wagner, E. Novel Shielded Transferrin-Polyethylene Glycol-Polyethylenimine/ DNA Complexes for Systemic Tumor-Targeted Gene Transfer. Bioconjugate Chem. 2003, 14 (1), 222-31.
    • (2003) Bioconjugate Chem , vol.14 , Issue.1 , pp. 222-231
    • Kursa, M.1    Walker, G.F.2    Roessler, V.3    Ogris, M.4    Roedl, W.5    Kircheis, R.6    Wagner, E.7
  • 14
    • 10044272240 scopus 로고    scopus 로고
    • Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors
    • Funhoff, A. M.; Van Nostrum, C. F.; Lok, M. C.; Kruijtzer, J. A.; Crommelin, D. J.; Hennink, W. E. Cationic polymethacrylates with covalently linked membrane destabilizing peptides as gene delivery vectors. J. Controlled Release 2005, 101 (1-3), 233-46.
    • (2005) J. Controlled Release , vol.101 , Issue.1-3 , pp. 233-246
    • Funhoff, A.M.1    Van Nostrum, C.F.2    Lok, M.C.3    Kruijtzer, J.A.4    Crommelin, D.J.5    Hennink, W.E.6
  • 15
    • 0030775528 scopus 로고    scopus 로고
    • The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
    • Tang, M. X.; Szoka, F. C. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 1997, 4 (8), 823-32.
    • (1997) Gene Ther , vol.4 , Issue.8 , pp. 823-832
    • Tang, M.X.1    Szoka, F.C.2
  • 16
    • 28444450817 scopus 로고    scopus 로고
    • In vivo tumor transfection mediated by polyplexes based on biodegradable poly(DMAEA)-phosphazene
    • De Wolf, H. K.; Luten, J.; Snel, C. J.; Oussoren, C.; Hennink, W. E.; Storm, G. In vivo tumor transfection mediated by polyplexes based on biodegradable poly(DMAEA)-phosphazene. J. Controlled Release 2005, 109 (1-3), 275-87.
    • (2005) J. Controlled Release , vol.109 , Issue.1-3 , pp. 275-287
    • De Wolf, H.K.1    Luten, J.2    Snel, C.J.3    Oussoren, C.4    Hennink, W.E.5    Storm, G.6
  • 17
    • 0023792919 scopus 로고
    • Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
    • Scudiero, D. A.; Shoemaker, R. H.; Pauli, K. D.; Monks, A.; Tierney, S.; Nofziger, T. H.; Currens, M. J.; Seniff, D.; Boyd, M. R. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res. 1988, 48 (17), 4827-33.
    • (1988) Cancer Res , vol.48 , Issue.17 , pp. 4827-4833
    • Scudiero, D.A.1    Shoemaker, R.H.2    Pauli, K.D.3    Monks, A.4    Tierney, S.5    Nofziger, T.H.6    Currens, M.J.7    Seniff, D.8    Boyd, M.R.9
  • 18
    • 0029004594 scopus 로고
    • Phenotypic variations and differential migration of NIH:OVCAR-3 ovarian carcinoma cells isolated from athymic mice
    • Veatch, A. L.; Carson, L. F.; Ramakrishnan, S. Phenotypic variations and differential migration of NIH:OVCAR-3 ovarian carcinoma cells isolated from athymic mice. Clin. Exp. Metastasis 1995, 13 (3), 165-72.
    • (1995) Clin. Exp. Metastasis , vol.13 , Issue.3 , pp. 165-172
    • Veatch, A.L.1    Carson, L.F.2    Ramakrishnan, S.3
  • 19
    • 0035041168 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity
    • Aoki, K.; Furuhata, S.; Hatanaka, K.; Maeda, M.; Remy, J. S.; Behr, J. P.; Terada, M.; Yoshida, T. Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity. Gene Ther. 2001, 8 (7), 508-14.
    • (2001) Gene Ther , vol.8 , Issue.7 , pp. 508-514
    • Aoki, K.1    Furuhata, S.2    Hatanaka, K.3    Maeda, M.4    Remy, J.S.5    Behr, J.P.6    Terada, M.7    Yoshida, T.8
  • 20
    • 0034997403 scopus 로고    scopus 로고
    • Non-viral vectors in cancer gene therapy: Principles and progress
    • Schatzlein, A. G. Non-viral vectors in cancer gene therapy: principles and progress. Anticancer Drugs 2001, 12 (4), 275-304.
    • (2001) Anticancer Drugs , vol.12 , Issue.4 , pp. 275-304
    • Schatzlein, A.G.1
  • 22
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris, M.; Steinlein, P.; Kursa, M.; Mechtler, K.; Kircheis, R.; Wagner, E. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 1998, 5 (10), 1425-33.
    • (1998) Gene Ther , vol.5 , Issue.10 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6
  • 23
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
    • Moghimi, S. M.; Symonds, P.; Murray, J. C.; Hunter, A. C.; Debska, G.; Szewczyk, A. A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol. Ther. 2005, 11 (6), 990-5.
    • (2005) Mol. Ther , vol.11 , Issue.6 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 25
    • 0033822731 scopus 로고    scopus 로고
    • Leclerc, G. M.; Boockfor, F. R.; Faught, W. J.; Frawley, L. S. Development of a destabilized firefly luciferase enzyme for measurement of gene expression. Biotechniques 2000,29 (3), 590-1, 594-6, 598 passim.
    • Leclerc, G. M.; Boockfor, F. R.; Faught, W. J.; Frawley, L. S. Development of a destabilized firefly luciferase enzyme for measurement of gene expression. Biotechniques 2000,29 (3), 590-1, 594-6, 598 passim.
  • 26
    • 33644908033 scopus 로고    scopus 로고
    • Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery
    • Regnstrom, K.; Ragnarsson, E. G.; Fryknas, M.; Koping-Hoggard, M.; Artursson, P. Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery. Pharm. Res. 2006, 23 (3), 475-82.
    • (2006) Pharm. Res , vol.23 , Issue.3 , pp. 475-482
    • Regnstrom, K.1    Ragnarsson, E.G.2    Fryknas, M.3    Koping-Hoggard, M.4    Artursson, P.5
  • 27
    • 0032473482 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in somatic gene therapy
    • Shapiro Ledley, T.; Ledley, F. D. Pharmacokinetic considerations in somatic gene therapy. Adv. Drug Deliv. Rev 1998, 30 (1-3), 133-150.
    • (1998) Adv. Drug Deliv. Rev , vol.30 , Issue.1-3 , pp. 133-150
    • Shapiro Ledley, T.1    Ledley, F.D.2
  • 28
    • 0036107039 scopus 로고    scopus 로고
    • The effect of cell division on the cellular dynamics of microinjected DNA and dextran
    • Ludtke, J. J.; Sebestyen, M. G.; Wolff, J. A. The effect of cell division on the cellular dynamics of microinjected DNA and dextran. Mol. Ther 2002, 5 (5 Part 1), 579-88.
    • (2002) Mol. Ther , vol.5 , Issue.5 PART 1 , pp. 579-588
    • Ludtke, J.J.1    Sebestyen, M.G.2    Wolff, J.A.3
  • 29
    • 0035850212 scopus 로고    scopus 로고
    • Evaluation of polyplexes as gene transfer agents
    • Gebhart, C. L.; Kabanov, A. V. Evaluation of polyplexes as gene transfer agents. J. Controlled Release 2001, 73 (2-3), 401-16.
    • (2001) J. Controlled Release , vol.73 , Issue.2-3 , pp. 401-416
    • Gebhart, C.L.1    Kabanov, A.V.2
  • 30
    • 4644286010 scopus 로고    scopus 로고
    • Effective polyethylenimine-mediated gene transfer into human endothelial cells
    • Zaric, V.; Weltin, D.; Erbacher, P.; Remy, J. S.; Behr, J. P.; Stephan, D. Effective polyethylenimine-mediated gene transfer into human endothelial cells. J. Gene Med. 2004, 6 (2), 176-84.
    • (2004) J. Gene Med , vol.6 , Issue.2 , pp. 176-184
    • Zaric, V.1    Weltin, D.2    Erbacher, P.3    Remy, J.S.4    Behr, J.P.5    Stephan, D.6
  • 31
    • 0344389048 scopus 로고    scopus 로고
    • Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: Physicochemical and transfection studies
    • Ruponen, M.; Yla-Herttuala, S.; Urtti, A. Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. Biochim. Biophys. Acta 1999, 1415 (2), 331-41.
    • (1999) Biochim. Biophys. Acta , vol.1415 , Issue.2 , pp. 331-341
    • Ruponen, M.1    Yla-Herttuala, S.2    Urtti, A.3
  • 33
    • 0021873625 scopus 로고
    • Hyaluronic acid content of effusions as a diagnostic aid for malignant mesothelioma
    • Roboz, J.; Greaves, J.; Silides, D.; Chahinian, A. P.; Holland, J. F. Hyaluronic acid content of effusions as a diagnostic aid for malignant mesothelioma. Cancer Res. 1985, 45 (4), 1850-4.
    • (1985) Cancer Res , vol.45 , Issue.4 , pp. 1850-1854
    • Roboz, J.1    Greaves, J.2    Silides, D.3    Chahinian, A.P.4    Holland, J.F.5
  • 34
    • 0035823546 scopus 로고    scopus 로고
    • Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes
    • Ruponen, M.; Ronkko, S.; Honkakoski, P.; Pelkonen, J.; Tammi, M.; Urtti, A. Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes. J. Biol. Chem. 2001, 276 (36), 33875-80.
    • (2001) J. Biol. Chem , vol.276 , Issue.36 , pp. 33875-33880
    • Ruponen, M.1    Ronkko, S.2    Honkakoski, P.3    Pelkonen, J.4    Tammi, M.5    Urtti, A.6
  • 35
    • 0037136420 scopus 로고    scopus 로고
    • Weigel, P. H.; Yik, J. H. Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors. Biochim. Biophys. Acta 2002, 17572 (2-3), 341-63.
    • Weigel, P. H.; Yik, J. H. Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors. Biochim. Biophys. Acta 2002, 17572 (2-3), 341-63.
  • 36
    • 0032933779 scopus 로고    scopus 로고
    • Expression of the hyaluronan receptor, CD44S, in epithelial ovarian cancer is an independent predictor of survival
    • Kayastha, S.; Freedman, A. N.; Piver, M. S.; Mukkamalla, J.; Romero-Guittierez, M.; Werness, B. A. Expression of the hyaluronan receptor, CD44S, in epithelial ovarian cancer is an independent predictor of survival. Clin. Cancer Res. 1999, 5 (5), 1073-6.
    • (1999) Clin. Cancer Res , vol.5 , Issue.5 , pp. 1073-1076
    • Kayastha, S.1    Freedman, A.N.2    Piver, M.S.3    Mukkamalla, J.4    Romero-Guittierez, M.5    Werness, B.A.6
  • 37
    • 0344420217 scopus 로고    scopus 로고
    • Understanding endocytic pathways and intracellular trafficking: A prerequisite for effective design of advanced drug delivery systems
    • Jones, A. T.; Gumbleton, M.; Duncan, R. Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems. Adv. Drug Deliv. Rev. 2003, 55 (11), 1353-7.
    • (2003) Adv. Drug Deliv. Rev , vol.55 , Issue.11 , pp. 1353-1357
    • Jones, A.T.1    Gumbleton, M.2    Duncan, R.3


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