-
1
-
-
0027342643
-
CpG islands
-
Antequera, F. & Bird, A. CpG islands. Exs., 64:169-85, 1993.
-
(1993)
Exs
, vol.64
, pp. 169-185
-
-
Antequera, F.1
Bird, A.2
-
2
-
-
0036561649
-
Altered methylation patterns in cancer cell genomes: Cause or consequence?
-
Baylin, S. & Bestor, T. H. Altered methylation patterns in cancer cell genomes: cause or consequence? Cancer Cell 1:299-305, 2002.
-
(2002)
Cancer Cell
, vol.1
, pp. 299-305
-
-
Baylin, S.1
Bestor, T.H.2
-
3
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin, S. B.; Herman, J. G.; Graff, J. R.; Vertino, P. M. & Issa, J. P. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv. Cancer Res., 72:141-96, 1998.
-
(1998)
Adv. Cancer Res
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
Vertino, P.M.4
Issa, J.P.5
-
4
-
-
0024268269
-
Structure of mammalian DNA methyltransferase as deduced from the inferred amino acid sequence and direct studies of the protein
-
Bestor, T. Structure of mammalian DNA methyltransferase as deduced from the inferred amino acid sequence and direct studies of the protein. Biochem. Soc. Trans., 16:944-7, 1988.
-
(1988)
Biochem. Soc. Trans
, vol.16
, pp. 944-947
-
-
Bestor, T.1
-
5
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. DNA methylation patterns and epigenetic memory. Genes Dev., 16:6-21, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
6
-
-
18944379452
-
-
Catalano, V.; Labianca, R.; Beretta, G. D.; Gatta, G.; de Braud, F. & Van Cutsem, E. Gastric cancer. Crit. Rev. Oncol. Hematol., 54:209-41, 2005.
-
Catalano, V.; Labianca, R.; Beretta, G. D.; Gatta, G.; de Braud, F. & Van Cutsem, E. Gastric cancer. Crit. Rev. Oncol. Hematol., 54:209-41, 2005.
-
-
-
-
7
-
-
24344500170
-
RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD
-
Chi, X.Z.; Yang, J.O.; Lee, K.Y.; Ito, K.; Sakakura, C.; Li, Q.L.; Kim, H.R.; Cha, E. J.; Lee, Y. H.; Kaneda, A.; Ushijima, T.; Kim, W. J.; Ito, Y. & Bae, S. C. RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD. Mol. Cell. Biol., 25:8097-107, 2005.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 8097-8107
-
-
Chi, X.Z.1
Yang, J.O.2
Lee, K.Y.3
Ito, K.4
Sakakura, C.5
Li, Q.L.6
Kim, H.R.7
Cha, E.J.8
Lee, Y.H.9
Kaneda, A.10
Ushijima, T.11
Kim, W.J.12
Ito, Y.13
Bae, S.C.14
-
8
-
-
0038440763
-
Runx transcription factors and the developmental balance between cell proliferation and differentiation
-
Coffman, J. A. Runx transcription factors and the developmental balance between cell proliferation and differentiation. Cell. Biol. Int., 27:315-24, 2003.
-
(2003)
Cell. Biol. Int
, vol.27
, pp. 315-324
-
-
Coffman, J.A.1
-
9
-
-
0036145156
-
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
-
Esteller, M. & Herman, J.G. Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours. J. Pathol., 196:1-7, 2002.
-
(2002)
J. Pathol
, vol.196
, pp. 1-7
-
-
Esteller, M.1
Herman, J.G.2
-
10
-
-
23044466047
-
Specificity and versatility in TGF-beta signaling through smads
-
Feng, X. H. & Derynck, R. Specificity and versatility in TGF-beta signaling through smads. Annu. Rev. Cell. Dev. Biol., 21:659-93, 2005.
-
(2005)
Annu. Rev. Cell. Dev. Biol
, vol.21
, pp. 659-693
-
-
Feng, X.H.1
Derynck, R.2
-
11
-
-
0033952575
-
DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis
-
Fujimoto, J.; Yasui, W.; Tahara, H.; Tahara, E.; Kudo, Y. & Yokozaki, H. DNA hypermethylation at the pS2 promoter region is associated with early stage of stomach carcinogenesis. Cancer Lett., 149:125-34, 2000.
-
(2000)
Cancer Lett
, vol.149
, pp. 125-134
-
-
Fujimoto, J.1
Yasui, W.2
Tahara, H.3
Tahara, E.4
Kudo, Y.5
Yokozaki, H.6
-
12
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden, M. & Frommer, M. CpG islands in vertebrate genomes. J. Mol. Biol., 196:261-82, 1987.
-
(1987)
J. Mol. Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
13
-
-
17144369504
-
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)- methyltransferases by Dnmt3L
-
Gowher, H.; Liebert, K.; Hermann, A.; Xu, G. & Jeltsch, A. Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)- methyltransferases by Dnmt3L. J. Biol. Chem. 280:13341-8, 2005.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 13341-13348
-
-
Gowher, H.1
Liebert, K.2
Hermann, A.3
Xu, G.4
Jeltsch, A.5
-
14
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Grace Goll, M. & Bestor, T. H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem., 74:481-514, 2005.
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 481-514
-
-
Grace Goll, M.1
Bestor, T.H.2
-
15
-
-
0020486108
-
Substrate and sequence specificity of a eukaryotic DNA methylase
-
Gruenbaum, Y.; Cedar, H. & Razin, A. Substrate and sequence specificity of a eukaryotic DNA methylase. Nature, 295:620-2, 1982.
-
(1982)
Nature
, vol.295
, pp. 620-622
-
-
Gruenbaum, Y.1
Cedar, H.2
Razin, A.3
-
16
-
-
0036333103
-
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
-
Hata, K.; Okano, M.; Lei, H. & Li, E. Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development, 129:1983-93, 2002.
-
(2002)
Development
, vol.129
, pp. 1983-1993
-
-
Hata, K.1
Okano, M.2
Lei, H.3
Li, E.4
-
17
-
-
0014936031
-
Reaction of sodium bisulfite with uracil, cytosine, and their derivatives
-
Hayatsu, H.; Wataya, Y.; Kai, K. & Iida, S. Reaction of sodium bisulfite with uracil, cytosine, and their derivatives. Biochemistry, 9:2858-65, 1970.
-
(1970)
Biochemistry
, vol.9
, pp. 2858-2865
-
-
Hayatsu, H.1
Wataya, Y.2
Kai, K.3
Iida, S.4
-
18
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman, J.G.; Graff, J.R.; Myohanen, S.; Nelkin, B.D. & Baylin, S.B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc. Natl. Acad. Sci. U S A., 93:9821-6, 1996a.
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
19
-
-
0030046322
-
-
Herman, J. G.; Jen, J.; Merlo, A. & Baylin, S.B. Hypermethylation- associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res., 56:722-7, 1996b.
-
Herman, J. G.; Jen, J.; Merlo, A. & Baylin, S.B. Hypermethylation- associated inactivation indicates a tumor suppressor role for p15INK4B. Cancer Res., 56:722-7, 1996b.
-
-
-
-
20
-
-
9744251005
-
Biochemistry and biology of mammalian DNA methyltransferases
-
Hermann, A.; Gowher, H. & Jeltsch, A. Biochemistry and biology of mammalian DNA methyltransferases. Cell Mol. Life Sci., 61:2571-87, 2004.
-
(2004)
Cell Mol. Life Sci
, vol.61
, pp. 2571-2587
-
-
Hermann, A.1
Gowher, H.2
Jeltsch, A.3
-
21
-
-
42449101858
-
-
INCA. Estimativa 2006: incidência câncer no Brasil. http://www.inca.org.br. Acessed November 12, 2005.
-
INCA. Estimativa 2006: incidência câncer no Brasil. http://www.inca.org.br. Acessed November 12, 2005.
-
-
-
-
22
-
-
23044457554
-
Role of de novo DNA methyltransferases in initiation of genomic imprinting and X-chromosome inactivation
-
Kaneda, M.; Sado, T.; Hata, K.; Okano, M.; Tsujimoto, N.; Li, E. & Sasaki, H. Role of de novo DNA methyltransferases in initiation of genomic imprinting and X-chromosome inactivation. Cold Spring. Harb. Symp. Quant. Biol., 69:125-9, 2004.
-
(2004)
Cold Spring. Harb. Symp. Quant. Biol
, vol.69
, pp. 125-129
-
-
Kaneda, M.1
Sado, T.2
Hata, K.3
Okano, M.4
Tsujimoto, N.5
Li, E.6
Sasaki, H.7
-
23
-
-
2342641616
-
Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma
-
Kim, T. Y.; Lee, H. J.; Hwang, K. S.; Lee, M.; Kim, J. W.; Bang, Y. J. & Kang, G. H. Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma. Lab. Invest., 84:479-84, 2004.
-
(2004)
Lab. Invest
, vol.84
, pp. 479-484
-
-
Kim, T.Y.1
Lee, H.J.2
Hwang, K.S.3
Lee, M.4
Kim, J.W.5
Bang, Y.J.6
Kang, G.H.7
-
24
-
-
0038576158
-
W.The power and the promise of DNA methylation markers
-
Laird, P. W.The power and the promise of DNA methylation markers. Nat. Rev. Cancer, 3:253-66, 2003.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.1
-
25
-
-
12644292106
-
The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma
-
Laurén, P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. Acta Pathologica et Microbiologica Scandinava, 64:31-49, 1965.
-
(1965)
Acta Pathologica et Microbiologica Scandinava
, vol.64
, pp. 31-49
-
-
Laurén, P.1
-
26
-
-
0042592885
-
EMBO Rep., 4
-
Levanon, D.; Brenner, O.; Otto, F. & Groner, Y. Runx3 knockouts and stomach cancer. EMBO Rep., 4:560-4, 2003.
-
(2003)
, pp. 560-564
-
-
Levanon, D.1
Brenner, O.2
Otto, F.3
Groner, Y.4
-
27
-
-
0036733675
-
Chromatin modification and epigenetic reprogramming in mammalian development
-
Li, E. Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet., 3:662-73, 2002.
-
(2002)
Nat. Rev. Genet
, vol.3
, pp. 662-673
-
-
Li, E.1
-
28
-
-
0036856355
-
MethPrimer: Designing primers for methylation PCRs
-
Li, L. C. & Dahiya, R. MethPrimer: designing primers for methylation PCRs. Bioinformatics, 18:1427-31, 2002.
-
(2002)
Bioinformatics
, vol.18
, pp. 1427-1431
-
-
Li, L.C.1
Dahiya, R.2
-
29
-
-
27744437224
-
Molecular study of the tumour suppressor gene PTEN in gastric adenocarcinoma in Brazil
-
Lima, E.M.; Araujo, J.J.; Harada, M.L.; Assumpcao, P.P.; Burbano, R.R. & Casartelli, C. Molecular study of the tumour suppressor gene PTEN in gastric adenocarcinoma in Brazil. Clin. Exp. Med., 5:129-32, 2005.
-
(2005)
Clin. Exp. Med
, vol.5
, pp. 129-132
-
-
Lima, E.M.1
Araujo, J.J.2
Harada, M.L.3
Assumpcao, P.P.4
Burbano, R.R.5
Casartelli, C.6
-
30
-
-
0038546417
-
Establishment and functional validation of a structural homology model for human DNA methyltransferase 1
-
Lyko, F. Establishment and functional validation of a structural homology model for human DNA methyltransferase 1. Biochem. Biophys Res. Commun 306:558-63, 2003.
-
(2003)
Biochem. Biophys Res. Commun
, vol.306
, pp. 558-563
-
-
Lyko, F.1
-
31
-
-
42449104043
-
-
Miller, M. P. Tools for population genetic analyses [TFPGA] 1.3: A Windows program for the analysis of allozime and molecular population genetic data. Computer software distributed by author, 1997
-
Miller, M. P. Tools for population genetic analyses [TFPGA] 1.3: A Windows program for the analysis of allozime and molecular population genetic data. Computer software distributed by author, 1997.
-
-
-
-
32
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M.; Bell, D.W.; Haber, D.A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-57, 1999.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
33
-
-
0032102949
-
Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
-
Okano. M.; Xie, S. & Li, E. Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acids Res., 26:2536-40, 1998.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 2536-2540
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
34
-
-
0026627772
-
Loss of heterozygosity for distal markers on 22q in human gliomas
-
Rey, J. A.; Bello, M. J.; Jimenez-Lara, A.M.; Vaquero, J.; Kusak, M. E.; de Campos, J. M.; Sarasa, J. L. & Pestana, A. Loss of heterozygosity for distal markers on 22q in human gliomas. Int. J. Cancer, 51:703-6, 1992.
-
(1992)
Int. J. Cancer
, vol.51
, pp. 703-706
-
-
Rey, J.A.1
Bello, M.J.2
Jimenez-Lara, A.M.3
Vaquero, J.4
Kusak, M.E.5
de Campos, J.M.6
Sarasa, J.L.7
Pestana, A.8
-
35
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee, I.; Bachman, K. E.; Park, B. H.; Jair, K.W.; Yen, R.W.; Schuebel, K. E.; Cui, H.; Feinberg, A. P.; Lengauer, C.; Kinzler, K.W.; Baylin, S. B.; & Vogelstein, B. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature, 416:552-6, 2002.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
36
-
-
0033153303
-
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson, K. D.; Uzvolgyi, E.; Liang, G.; Talmadge, C.; Sumegi, J.; Gonzales, F. A. & Jones, P. A. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res., 27:2291-8, 1999.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgyi, E.2
Liang, G.3
Talmadge, C.4
Sumegi, J.5
Gonzales, F.A.6
Jones, P.A.7
-
37
-
-
0037130479
-
The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines
-
Sato, M.; Horio, Y.; Sekido, Y.; Minna, J.D.; Shimokata, K. & Hasegawa, Y. The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines. Oncogene, 21:4822-9, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 4822-4829
-
-
Sato, M.1
Horio, Y.2
Sekido, Y.3
Minna, J.D.4
Shimokata, K.5
Hasegawa, Y.6
-
38
-
-
0014933620
-
Specific deamination of RNA by sodium bisulphite
-
Shapiro, R.; Cohen, B. & Servis, R.E. Specific deamination of RNA by sodium bisulphite. Nature, 227:1047-8, 1970.
-
(1970)
Nature
, vol.227
, pp. 1047-1048
-
-
Shapiro, R.1
Cohen, B.2
Servis, R.E.3
-
39
-
-
2942622388
-
The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms
-
Siedlecki, P.; Boy, R.G.; Comagic, S.; Schirrmacher, R.; Wiessler, M.; Zielenkiewicz, P.; Suhai, S.; Rennert, J.; Coffman, J. A.; Mushegian, A. R. & Robertson, A. J. The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms. BMC Evol. Biol., 3:4, 2003.
-
(2003)
BMC Evol. Biol
, vol.3
, pp. 4
-
-
Siedlecki, P.1
Boy, R.G.2
Comagic, S.3
Schirrmacher, R.4
Wiessler, M.5
Zielenkiewicz, P.6
Suhai, S.7
Rennert, J.8
Coffman, J.A.9
Mushegian, A.R.10
Robertson, A.J.11
-
40
-
-
42449146712
-
-
Stewart, B. W. & Kleihues, P, Eds, IARCPress, Lyon, p
-
Stewart, B. W. & Kleihues, P. (Eds) World Cancer Report. IARCPress, Lyon, p.35, 2003.
-
(2003)
World Cancer Report
, pp. 35
-
-
-
41
-
-
0035895505
-
The sequence of the human genome
-
Venter, J. C.; Adams, M. D.; Myers, E.W.; Li, P. W.; Mural, R. J.; Sutton, G. G. & Smith, H.O. The sequence of the human genome. Science, 291:1304-51, 2001.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
-
42
-
-
1842851793
-
Genetic pathways of two types of gastric cancer
-
Tahara, E. Genetic pathways of two types of gastric cancer. IARC Sci. Publ.,:327-49, 2004.
-
(2004)
IARC Sci. Publ
, vol.327 -49
-
-
Tahara, E.1
-
43
-
-
0036165983
-
Genetic and epigenetic alterations of tumor suppressor and tumor-related genes in gastric cancer
-
Tamura, G.: Genetic and epigenetic alterations of tumor suppressor and tumor-related genes in gastric cancer. Histol. Histopathol., 17:323-9, 2002.
-
(2002)
Histol. Histopathol
, vol.17
, pp. 323-329
-
-
Tamura, G.1
-
44
-
-
0032769445
-
-
Xie, S.; Wang, Z.; Okano, M.; Nogami, M.; Li, Y.; He, W.W.; Okumura, K. & Li, E. Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene, 236:87-95, 1999.
-
Xie, S.; Wang, Z.; Okano, M.; Nogami, M.; Li, Y.; He, W.W.; Okumura, K. & Li, E. Cloning, expression and chromosome locations of the human DNMT3 gene family. Gene, 236:87-95, 1999.
-
-
-
-
45
-
-
0036789450
-
High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma
-
Zhang, Y.J.; Ahsan, H.; Chen, Y.; Lunn, R.M.; Wang, L.Y.; Chen, S.Y.; Lee, P.H.; Chen, C.J. & Santella, R.M. High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma. Mol. Carcinog., 35:85-92, 2002.
-
(2002)
Mol. Carcinog
, vol.35
, pp. 85-92
-
-
Zhang, Y.J.1
Ahsan, H.2
Chen, Y.3
Lunn, R.M.4
Wang, L.Y.5
Chen, S.Y.6
Lee, P.H.7
Chen, C.J.8
Santella, R.M.9
-
46
-
-
0038527233
-
Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia
-
Waki, T.; Tamura, G.; Sato, M.; Terashima, M.; Nishizuka, S. & Motoyama, T. Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia. Cancer Sci., 94:360-4, 2003.
-
(2003)
Cancer Sci
, vol.94
, pp. 360-364
-
-
Waki, T.1
Tamura, G.2
Sato, M.3
Terashima, M.4
Nishizuka, S.5
Motoyama, T.6
-
47
-
-
0019332015
-
Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues
-
Wang, R.Y.; Gehrke, C.W. & Ehrlich, M. Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues. Nucleic Acids Res., 8:4777-90, 1980.
-
(1980)
Nucleic Acids Res
, vol.8
, pp. 4777-4790
-
-
Wang, R.Y.1
Gehrke, C.W.2
Ehrlich, M.3
|