Runx3 knockouts and stomach cancer. The challenge of identifying phenotypic defects directly attributable to loss of gene function

EMBO Reports

Volumn 4, Issue 6, 2003, Pages 560-564

  Levanon, Ditsa ^a   Brenner, Ori ^a   Otto, Florian ^b   Groner, Yoram ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG; BETA GALACTOSIDASE; PROTEIN P53; TELOMERASE;

DEVELOPMENT; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE LOSS; GENE MUTATION; GENE TARGETING; GENETIC DISORDER; GENETIC LINE; KNOCKOUT GENE; KNOCKOUT MOUSE; MOUSE; MOUSE STRAIN; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; STOMACH CANCER; STOMACH CARCINOGENESIS; THYMUS FUNCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MORTALITY; CONTROLLED STUDY; DNA BINDING; EXPRESSED SEQUENCE TAG; GENE; GENE INACTIVATION; INTERNAL RIBOSOME ENTRY SITE; MONOSYNAPTIC REFLEX; NERVE CELL; PROMOTER REGION; RUNX3 GENE; STOMACH EPITHELIUM; TRANSCRIPTION INITIATION SITE; UPREGULATION;

ANIMALS; CELL LINEAGE; CORE BINDING FACTOR ALPHA 3 SUBUNIT; DNA METHYLATION; DNA-BINDING PROTEINS; HUMANS; MICE; MICE, KNOCKOUT; MODELS, GENETIC; MUTATION; PHENOTYPE; PROMOTER REGIONS (GENETICS); PROTEIN STRUCTURE, TERTIARY; STOMACH NEOPLASMS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0042592885     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.embor868     Document Type: Review

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