Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 8, 2008, Pages 4509-4515

  Behrouzi Fardmoghadam, Mina ^a   Poorrajab, Fatemeh ^b   Ardestani, Sussan Kaboudanian ^b   Emami, Saeed ^c   Shafiee, Abbas ^a   Foroumadi, Alireza ^a  

^a Tehran University of Medical Science   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

^c MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

1,3,4 Thiadiazole; Amastigote; Anti leishmanial activity; Leishmania major; Nitrofuran; Nitrothiophene; Promastigote

Indexed keywords

1 [5 (5 NITROFURAN 2 YL) 1,3,4 THIADIAZOL 2 YL] 4 AROYLPIPERAZINE DERIVATIVE; 1 [5 (5 NITROTHIOPHEN 2 YL) 1,3,4 THIADIAZOL 2 YL] 4 AROYLPIPERAZINE DERIVATIVE; ANTIPROTOZOAL AGENT; UNCLASSIFIED DRUG;

AMASTIGOTE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; LEISHMANIASIS; NONHUMAN; PROMASTIGOTE;

ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; FURANS; LEISHMANIA MAJOR; MACROPHAGES; MICE; MOLECULAR STRUCTURE; NITROGEN COMPOUNDS; PIPERAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

LEISHMANIA MAJOR;

EID: 42149170805     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.02.052     Document Type: Article

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