Antituberculosis agents. V. Synthesis, evaluation of in vitro antituberculosis activity and cytotoxicity of some 2-(5-nitro-2-furyl)-1,3,4-thiadiazole derivatives

Farmaco

Volumn 57, Issue 9, 2002, Pages 765-769

  Foroumadi, Alireza ^a   Asadipour, Ali ^a   Mirzaei, Maryam ^a   Karimi, Javad ^a   Emami, Saeed ^a  

^a KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antituberculosis agents; Cytotoxicity; Minimum inhibitory concentration

Indexed keywords

2 (2 CHLORO 6 FLUOROBENZYL)SULFONYL 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (2 CHLORO 6 FLUOROBENZYL)THIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (2,5 DIMETHYLBENZYL)SULFONYL 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (2,5 DIMETHYLBENZYL)THIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (4 CHLOROBENZYL)SULFONYL 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (4 CHLOROBENZYL)THIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (4 METHOXYBENZYL)THIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (4 NITROBENZYL)SULFONYL 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (4 NITROBENZYL)THIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 ETHYLSULFINYL 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 ETHYLSULFONYL 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 ETHYLTHIO 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 METHYLSULFINYL 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 METHYLSULFONYL 1,3,4 THIADIAZOLE; 2 (5 NITRO 2 FURYL) 5 METHYLTHIO 1,3,4 THIADIAZOLE; 2 BENZYLSULFONYL 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; 2 BENZYLTHIO 5 (5 NITRO 2 FURYL) 1,3,4 THIADIAZOLE; THIADIAZOLE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; DILUTION; DRUG ACTIVITY; DRUG OXIDATION; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RADIOMETRY; ANIMAL; CELL SURVIVAL; CERCOPITHECUS; DRUG EFFECT; IC 50; MICROBIOLOGICAL EXAMINATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS; VERO CELL;

ANIMALS; ANTITUBERCULAR AGENTS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES; VERO CELLS;

EID: 0036754299     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(02)01277-6     Document Type: Article

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