Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 7, 2003, Pages 1381-1387

  Khan, Khalid Mohammad ^a   Rasheed, Maimona ^a   Ullah, Zia ^a   Hayat, Safdar ^a   Kaukab, Farhana ^a   Choudhary, M Iqbal ^a   Ur Rahman, Atta ^a   Perveen, Shahnaz ^a  

^a UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYBENZOHYDRAZIDE; 2 METHYLBENZOHYDRAZIDE; 2 METHYLPROPANOHYDRAZIDE; 2 NAPHTHOYLHYDRAZIDE; 3 BENZYLOXYBENZOHYDRAZIDE; 4 BENZYLOXYBENZOHYDRAZIDE; 4 BENZYLOXYBENZOYL N' 2 CYANOETHYLBENZOHYDRAZIDE; 4 HYDROXYBENZOHYDRAZIDE; 4 METHYLBENZOHYDRAZIDE; ACETOHYDRAZIDE; ALKYL GROUP; ANTILEISHMANIAL AGENT; BENZOHYDRAZIDE; BUTANOHYDRAZIDE; ESTER DERIVATIVE; FUNCTIONAL GROUP; HALIDE; HEXANOHYDRAZIDE; HYDRAZIDE DERIVATIVE; HYDRAZINE; N' BENZOYL 4 BENZYLOXYBENZOHYDRAZIDE; N',N' DIBENZYL 4 BENZYLOXYBENZOHYDRAZIDE; NICOTINOHYDRAZIDE; NONANOHYDRAZIDE; PHENYLACETYLHYDRAZIDE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROPANOHYDRAZIDE; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; LEISHMANIASIS; NONHUMAN; SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

EID: 0037375616     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00611-9     Document Type: Article

References (24)

1. Berman J.D. Rev. Infect. Dis. 10:1988;560.
2. For a review see: Ram V.J., Nath M. Curr. Med. Chem. 3:1996;303.
3. Rasheed, M. Dissertation, University of Karachi, Pakistan, 2001.
4. Steck E.A. The Chemotherapy of Protozoan Disease. Vol. 2:1972;Walter Reed Army Institute of Research, Washington DC.
5. Cappucino E.F., Stauber L.A. Proc. Soc. Exptl. Biol. Med. 101:1959;742.
6. Pitzer K.K., Werbovetz K.A., Brendle J.J., Scovill J.P. J. Med. Chem. 41:1998;4885.
7. Buu-Hoï Ng.Ph., Xuong Ng.D., Nam Ng.H., Binon F., Royer R. J. Chem. Soc. 1953;1358.
8. Waisser K., Odlerova Z., Houngbedji N., Thiel W., Mayer R. Zentralbl. Mikrobiol. 144:1989;355.
9. Waisser K., Houngbedji N., Odlerova Z., Thiel W., Mayer R. Pharmazie. 45:1990;141.
10. Ciugureanu C., Ungureanu M., Grosu G. Rev. Med. -Chir. 97:1993;433.
11. Fukujiro F., Kunio N., Akimasa T., Yuhei H., Tokugoro O., Takeya H., Motohisa F. J. Pharm. Soc. Jpn. 74:1954;884.
12. Schering A.-G. Neth. Appl. 6,612,874, March 15, 1967; Chem. Abstr. 68:1968;59334u.
13. Thu-Cuc Ng.T., Buu-Hoï Ng.P., Xuong N.D. J. Med. Pharm. Chem. 3:1961;361.
14. Hall L.H., Mohney B.K., Kier L.B. Quant. Struct. -Act. Relat. 12:1993;44.
15. Cardellini M., Claudi F., Grifantini M., Gulini U., Martelli S. J. Pharm. Sci. 66:1977;259.
16. Safrazbekyan R.R., Sukasyan R.S., Arzanunts E.M. Vopr. Med. Khim. 25:1979;311.
17. Khan K.M., Saify Z.S., Zeeshan, Khan A., Ahmed M., Saeed M., Abdel-Jalil R.J., Grubler G., Voelter W. Z. Naturforsch. 54b:1999;1210.
18. Khan K.M., Saify Z.S., Zeeshan, Khan A., Ahmed M., Saeed M., Schick M., Kohlbau H.J., Voleter W. Arzneim.-Forsch./Drug Res. 50:2000;915.
19. Saify Z.S., Khan K.M., Haider S.M., Zeeshan, Shah S.T.A., Saeed M., Shekhani M.S., Voelter W. Z. Naturforsch. 54b:1999;1327.
20. Zaidi J.H., Naeem F., Iqbal R., Choudhary M.I., Khan K.M., Shah S.T.A., Hayat S., Voelter W. Z. Naturforsch. 56b:2001;689.
21. Khan K.M., Saify Z.S., Shah S.T.A., Ahmed M., Saeed M., Hayat S., Abbas M., Voelter W. Arzneim.-Forsch./Drug Res. 52:2002;286.
22. Khan K.M., Rahat S., Choudhary M.I., Atta-ur-Rahman, Ghani U., Perveen S., Khatoon S., Dar A., Malik A. Helv. Chim. Acta. 85:2002;559.
23. Atta-ur-Rahman, Choudhary M.I., Thomsen W.J. Bioassay Techniques for Drug Development. 2001;Harwood Academic Publishers, The Netherlands. pp. 60-64.
24. Yale H.I., Losee K., Martin J., Hervy H., Pervy F.M., Bernstain J. J. Am. Chem. Soc. 75:1953;1933.