A comparative study of mesoionic compounds in Leishmania sp. and toxicity evaluation

European Journal of Medicinal Chemistry

Volumn 42, Issue 7, 2007, Pages 1039-1043

  Rodrigues, Raquel F ^a   da Silva, Edson F ^b   Aurea Echevarria ^b   Fajardo Bonin, Renata ^a   Amaral, Veronica F ^c   Leon, Leonor L ^a   Canto Cavalheiro, Marilene M ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL RURAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Antileishmanial activity; Mesoionic derivatives; Toxicity

Indexed keywords

1,3,4 THIADIAZOLIUM 2 PHENYLAMINE DERIVATIVE; 4 PHENYL 5 (4 NITROCINNAMOYL) 1,3,4 THIADIAZOLIUM 2 PHENYLAMINE CHLORIDE; AMPHOLYTE; MILTEFOSINE; PENTAMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; LEISHMANIA; MACROPHAGE; MOUSE; NONHUMAN;

ANIMALS; ANTIPROTOZOAL AGENTS; HYDROGEN-ION CONCENTRATION; LEISHMANIA; MACROPHAGES; MICE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34250166127     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.12.026     Document Type: Article

References (26)

1. Tropical Disease Research, Progress1997-1998 (1999), World Health Organization, Geneva
2. Desjeux P. Comp. Immunol. Microbiol. Infect. Dis. 27 (2004) 305-318
3. Carvalho P.B., Arriibas M.A., and Ferreira E.I. Braz. J. Pharm. Sci. 36 (2002) 69-96
4. Singh S., and Sivakumar R. J. Infect. Chemother. 10 (2004) 307-315
5. Croft S.L., Seifert K., and Yardley V. Indian J. Med. Res. 123 (2006) 399-410
6. Silva E.F., Canto-Cavalheiro M.M., Braz V.R., Cysne-Finkelstein L., Leon L.L., and Echevarria A. Eur. J. Med. Chem. 37 (2002) 979-984
7. Kier L.B., and Roche E.B. J. Pharm. Sci. 56 (1967) 149-168
8. Àvalos M., Babiano R., Cintas P., Jiménez J.L., and Palacios J.C. Acc. Chem. Res. 38 (2005) 460-468
9. Cadena S.M.S.C., Carnieri E.G.S., Echevarria A., and de Oliveira M.B.M. FEBS Lett. 440 (1998) 46-50
10. Senff-Ribeiro A., Echevarria A., Silva E.F., Veiga S.S., and Oliveira M.B.M. Melanoma Res. 13 (2003) 465-471
11. Grynberg N., Santos A.C., and Echevarria A. Anticancer Drugs 8 (1997) 88-91
12. Corell T., Pedersen S.B., Lissau B., Moilanen E., Metsa-Ketela T., Kankaanranta H., Vuorinen P., Vapaatalo H., Rydell E., Andersson R., Marcinkiewicz E., Korbut R., and Gryglewski R.J. Pol. J. Pharmacol. 46 (1994) 553-566
13. Schonafinger K. Il Farmaco 54 (1999) 316-320
14. Mauels S., and Ransijn A. Exp. Parasitol. 87 (1997) 98-111
15. Hellberg M., Stubbins J.F., and Glennon R.A. Bioorg. Med. Chem. 8 (2000) 1917-1923
16. Sen D.K., Mbagwu G.O., and Adson A. J. Eukaryot. Microbiol. 40 (1993) 259-262
17. Croft S.L., Neal R.A., Pendergast N., and Chan J.H. Biochem. Pharmacol. 36 (1987) 2633-2636
18. Croft S.L., Snowdon D., and Yardley V. J. Antimicrob. Chemother. 38 (1996) 1041-1047
19. Leon L.L., Machado G.M.C., Carvalho-Paes L.E., and Grimaldi Jr. G. Trans. R. Soc. Trop. Med. Hyg. 84 (1990) 678-680
20. Barral A., Pedral-Sampaio D., Grimaldi Jr. G., Momen H., McMahon-Pratt D., Ribeiro de Jesus A., Almeida R., Badaró R., Barral-Neto M., Carvalho E.M., and Johnson Jr. W.D. Am. J. Trop. Med. Hyg. 44 (1991) 536-546
21. Stewart T.G., and Kier L.B. J. Pharm. Sci. 54 (1965) 731-734
22. Roberts C.W., McLeod R., Rice D.W., Ginger M., Chance M.L., and Goad L.J. Mol. Biochem. Parasitol. 126 (2003) 129-142
23. Escobar P., Matu S., Marques C., and Croft S.L. Acta Trop. 81 (2002) 151-157
24. Neidle N., and Eder R. Arzneim. Forsch. Drug Res. 10 (1982) 1292-1298
25. House H.O. Modern Synthetic Reactions. second ed. (1972), The Benjamin Cumming Publishing Company, Menlo Park, California
26. Denizot F., and Lang R. J. Immunol. Methods 22 (1986) 271-277