Synthesis, analytical behaviour and biological evaluation of new 4-substituted pyrrolo[1,2-a]quinoxalines as antileishmanial agents

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 1, 2007, Pages 194-210

  Guillon, Jean ^a   Forfar, Isabelle ^a   Mamani Matsuda, Maria ^b   Desplat, Vanessa ^b   Saliège, Marion ^a   Thiolat, Denis ^b   Massip, Stéphane ^a   Tabourier, Anais ^a   Léger, Jean Michel ^a   Dufaure, Benoit ^a   Haumont, Gilbert ^b   Jarry, Christian ^a   Mossalayi, Djavad ^b  

^a Laboratoire de Pharmacochimie   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Antileishmanial activity; Lipohilicity; Pyrrolo 1,2 a quinoxaline derivatives; Synthesis

Indexed keywords

ANTILEISHMANIAL AGENT; QUINOXALINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEISHMANIA; LEISHMANIA DONOVANI; NONHUMAN; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; ANTIPROTOZOAL AGENTS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROPHOBICITY; LEISHMANIA; LEUKOCYTES, MONONUCLEAR; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; QUINOXALINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

GALIPEA; LEISHMANIA AMAZONENSIS; LEISHMANIA INFANTUM;

EID: 33750952888     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.068     Document Type: Article

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