Activity of megazol, a trypanocidal nitroimidazole, is associated with DNA damage

Antimicrobial Agents and Chemotherapy

Volumn 47, Issue 10, 2003, Pages 3368-3370

  Enanga, Bertin ^a   Ariyanayagam, Mark R ^b   Stewart, Mhairi L ^a   Barrett, Michael P ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 (1 METHYL 5 NITRO 2 IMIDAZOLYL) 1,3,4 THIADIAZOLE; ANTITRYPANOSOMAL AGENT; DNA BINDING PROTEIN; NITROIMIDAZOLE; THIADIAZOLE DERIVATIVE;

ANIMAL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CHEMISTRY; CROSS RESISTANCE; DNA DAMAGE; DNA REPAIR; DRUG EFFECT; DRUG TRANSPORT; GENETICS; IC 50; MULTIDRUG RESISTANCE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA BRUCEI;

ANIMALS; DNA DAMAGE; DNA-BINDING PROTEINS; DRUG RESISTANCE, MULTIPLE; INHIBITORY CONCENTRATION 50; MUTATION; THIADIAZOLES; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0141890228     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.47.10.3368-3370.2003     Document Type: Article

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