Laser microbeams and optical tweezers to study DNA repair and ageing

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 6644, Issue , 2007, Pages

  Grigaravicius, Paulius ^a   Monajembashi, Shamci ^a   Pilarczyk, Götz ^c   Rapp, Alexander ^a,b   Greulich, Karl Otto ^a  

^a FRITZ LIPMANN INSTITUTE   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM COMPOUNDS; CELLS; DNA; OPTICAL TWEEZERS;

CALCIUM HOMEOSTASIS; DNA REPAIR; LASER MICROBEAMS;

LASER BEAMS;

EID: 42149084374     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.735816     Document Type: Conference Paper

References (36)

1. J.Essers, W.Vermeulen, and A.B.Houtsmuller. "DNA damage repair: anytime, anywhere?". Curr. Opin. Cell Biol. 18(3), 240-246 (2006).
2. L.Tartier, C.Spenlehauer, H.C.Newman, M.Folkard, K.M.Prise, B.D.Michael, J.Menissier-de Murcia, and G.de Murcia. "Local DNA damage by proton microbeam irradiation induces poly(ADP-ribose) synthesis in mammalian cells". Mutagenesis, 18(5), 411-416 (2003).
3. M.Heiss, B.E.Fischer, B.Jakob, C.Fournier, G.Becker, and G.Taucher-Scholz. "Targeted irradiation of Mammalian cells using a heavy-ion microprobe". Radiat. Res., 165(2), 231-239 (2006).
4. K.M.Prise, O.V.Belyakov, M.Folkard, and B.D.Michael. "Studies of bystander effects in human fibroblasts using a charged particle microbeam". Int. J. Radiat. Biol., 74(6), 793-798 (1998).
5. N.Hamada, G.Schettino, G.Kashino, M.Vaid, K.Suzuki, S.Kodama, B.Vojnovic, M.Folkard, M.Watanabe, B.D.Michael, and K.M.Prise. "Histone H2AX phosphorylation in normal human cells irradiated with focused ultrasoft X rays: Evidence for chromatin movement during repair". Radiat. Res., 166(1), 31-38 (2006).
6. N.Desai, E.Davis, P.O'Neill, M.Durante, E.A.Cucinotta, and H.Wu. "Immunofluorescence detection of clustered gamma-H2AX foci induced by HZE-particle radiation". Radiat. Res., 164(4), 518-522 (2005).
7. A.Hauptner, T.Cremer, M.Deutsch, S.Dietzel, G.A.Drexler, C.Greubel, V.Hable, R.Krucken, R.Xowe, H.Strickfaden, G.Dollinger, and A.A.Friedl. "Irradiation of living cells with single ions at the ion microprobe SNAKE". Acta Physica Polonica A, 109(3), 273-278 (2006).
8. B.Jakob, J.H.Rudolph, N.Gueven, M.E.Lavin, and G.Taucher-Scholz. "Live cell imaging of heavy-ion-induced radiation responses by beamline microscopy". Radiat. Res., 163(6), 681-690 (2005).
9. A.Rodrigue, M.Lafrance, M.C.Gauthier, D.McDonald, M.Hendzel, S.C.West, M.Jasin, and J.Y.Masson. "Interplay between human DNA repair proteins at a unique double-strand break in vivo". EMBO Journal, 25(1), 222-231 (2006).
10. T.Miyazaki, D.A.Bressan, M.Shinohara, J.E.Haber, and A.Shinohara. "In vivo assembly and disassembly of Rad51 and Rad52 complexes during double-strand break repair". EMBO Journal, 23(4), 939-949 (2004).
11. A.Rapp and K.O.Greulich. "After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available". J. Cell Sci., 117(21), 4935-4945 (2004).
12. K.O.Greulich. Micromanipulation by Light in Biology and Medicine - The laser microbeam and optical tweezers. Birkhaeuser, Basel, Switzerland, 1999.
13. M.W.Berns and K.O.Greulich. Methods in Cell Biology: Laser Manipulation of Cells and Tissues. Elsevier, New York, 2007.
14. R.A.Meldrum, S.W.Botchway, C.W.Wharton, and G.J.Hirst. "Nanoscale spatial induction of ultraviolet photoproducts in cellular DNA by three-photon near-infrared absorption". EMBO Rep., 4(12), 1144-1149 (2003).
15. C.Lukas, J.Bartek, and J.Lukas. "Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges". Chromosoma, 114(3), 146-154 (2005).
16. E.P.Rogakou, C.Boon, C.Redon, and W.M.Bonner. "Megabase chromatin domains involved in DNA double-strand breaks in vivo". J. Cell Biol., 146(5), 905-916 (1999).
17. A.Celeste, O.Fernandez-Capetillo, M.J.Kruhlak, D.R.Pilch, D.W.Staudt, A.Lee, R.F.Bonner, W.M.Bonner, and A.Nussenzweig. "Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks". Nat. Cell Biol., 5(7), 675-679 (2003).
18. S.Bekker-Jensen, C.Lukas, R.Kitagawa, F.Melander, M.B.Kastan, J.Bartek, and J.Lukas. "Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks". J. Cell Biol., 173(2), 195-206 (2006).
19. S.Bekker-Jensen, C.Lukas, F.Melander, J.Bartek, and J.Lukas. "Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1". J. Cell Biol., 170(2), 201-211 (2005).
20. C.Lukas, J.Falck, J.Bartkova, J.Bartek, and J.Lukas. "Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage". Nat. Cell Biol., 5(3), 255-U12 (2003).
21. P.S.Bradshaw, D.J.Stavropoulos, and M.S.Meyn. "Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage". Nat. Genetics, 37(2), 193-197 (2005).
22. P.O.Mari, B.I.Florea, S.P.Persengiev, N.S.Verkaik, H.T.Brueggenwirth, M.Modesti, G.Giglia-Mari, K.Bezstarosti, J.A.A.Demmers, T.M.Luider, A.B.Houtsmuller, and D.C.van Gent. "Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4". P. N. A. S., 103(49), 18597-18602 (2006).
23. N.Uematsu, E.Weterings, K.Yano, K.Morotomi-Yano, B.Jakob, G.Taucher-Scholz, P.O.Mari, D.C.van Gent, B.P.C.Chen, and D.J.Chen. "Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks". J. Cell Biol, 177(2), 219-229 (2007).
24. K.Hashiguchi, Y.Matsumoto, and A.Yasui. "Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells". Nucleic Acids Res., 35(9), 2913-2923 (2007).
25. J.Walter, T.Cremer, K.Miyagawa, and S.Tashiro. "A new system for laser-UVA-microirradiation of living cells". J. Microsc, 209(2), 71-75 (2003).
26. M.J.Kruhlak, A.Celeste, G.Dellaire, O.Fernandez-Capetillo, W.G.Muller, J.G.McNally, D.P.Bazett-Jones, and A.Nussenzweig. "Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks". J. Cell Biol., 172(6), 823-834 (2006).
27. J.S.Kim, T.B.Krasieva, H.Kurumizaka, D.J.Chen, A.M.Taylor, and K.Yokomori. "Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells". J. Cell Biol., 170(3), 341-347 (2005).
28. C.Dinant, M.de Jager, J.Essers, W.A.van Cappellen, R.Kanaar, A.B.Houtsmuller, and W.Vermeulen. "Activation of multiple DNA repair pathways by sub-nuclear damage induction methods". J. Cell Sci., 120(15), 2731-2740 (2007).
29. K.Konig, I.Riemann, P.Fischer, and K.J.Halbhuber. "Intracellular nanosurgery with near infrared femtosecond laser pulses". Cell Mol. Biol, 45(2), 195-201 (1999).
30. S.K.Mohanty, A.Rapp, S.Monajembashi, P.K.Gupta, and K.O.Greulich. "Comet assay measurements of DNA damage in cells by laser microbeams and trapping beams with wavelengths spanning a range of 308 nm to 1064 nm". Radiat. Res., 157(4), 378-385 (2002).
31. A.de With and K.O.Greulich. "Wavelength dependence of laser-induced DNA damage in lymphocytes observed by single-cell gel electrophoresis". J. Photochem. Photobiol. B, 30(1), 71-76 (1995).
32. B.Perner, S.Monajembashi, A.Rapp, L.Wollweber, and K.O.Greulich. Simulation of heart infraction by laser microbeams and induction of arrhythmias by optical tweezers. Proceedings of SPIE 5514, 179-188. 2004.
33. M.D.Abramoff, P.J.Magelhaes, and S.J.Ram. "Image Processing with ImageJ". Biophot. Int., 11(7), 36-42 (2004).
34. J.A.Aten, J.Stap, P.M.Krawczyk, C.H.van Oven, R.A.Hoebe, J.Essers, and R.Kanaar. "Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains". Science, 303(5654), 92-95 (2004).
35. L.Lan, S.Nakajima, K.Komatsu, A.Nussenzweig, A.Shimamoto, J.Oshima, and A.Yasui. "Accumulation of Werner protein at DNA double-strand breaks in human cells". J. Cell Sci., 118(18), 4153-4162 (2005).
36. M.Lisby, U.H.Mortensen, and R.Rothstein. "Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre". Nat. Cell Biol, 5(6), 572-577 (2003).