-
1
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe D.J. The molecular pathology of Alzheimer's disease. Neuron 6 (1991) 487-498
-
(1991)
Neuron
, vol.6
, pp. 487-498
-
-
Selkoe, D.J.1
-
2
-
-
0023109592
-
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus
-
Tanzi R.E., Gusella J.F., Watkins P.C., Bruns G.A., St. George-Hyslop P., Van Keuren M.L., et al. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus. Science 235 (1987) 880-884
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
Bruns, G.A.4
St. George-Hyslop, P.5
Van Keuren, M.L.6
-
3
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., Lemaire H.-G., Unterbeck A., Salbaum J.M., Masters S.L., Grzesckik K.H., et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325 (1987) 733-736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.-G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, S.L.5
Grzesckik, K.H.6
-
4
-
-
0033609008
-
Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease
-
Knowles R.B., Wyart C., Buldyrev S.V., Cruz L., Urbanc B., Hasselmo M.E., et al. Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease. Proc Natl Acad Sci USA 96 (1999) 5274-5279
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5274-5279
-
-
Knowles, R.B.1
Wyart, C.2
Buldyrev, S.V.3
Cruz, L.4
Urbanc, B.5
Hasselmo, M.E.6
-
5
-
-
0347987853
-
Folding proteins in fatal ways
-
Selkoe D.J. Folding proteins in fatal ways. Nature 426 (2003) 900-904
-
(2003)
Nature
, vol.426
, pp. 900-904
-
-
Selkoe, D.J.1
-
6
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA 95 (1998) 6448-6453
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
-
7
-
-
0033520461
-
Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
Walsh D.M., Hartley D.M., Kusumoto Y., Fezoui Y., Condron M.M., Lomakin A., et al. Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J Biol Chem 274 (1999) 25945-25952
-
(1999)
J Biol Chem
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
-
8
-
-
0037200117
-
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability
-
Dahlgren K.N., Manelli A.M., Stine Jr. W.B., Baker L.K., Krafft G.A., and LaDu M.J. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J Biol Chem 277 (2002) 32046-32053
-
(2002)
J Biol Chem
, vol.277
, pp. 32046-32053
-
-
Dahlgren, K.N.1
Manelli, A.M.2
Stine Jr., W.B.3
Baker, L.K.4
Krafft, G.A.5
LaDu, M.J.6
-
9
-
-
36048941372
-
Peptide fibrillization
-
Hamley I.W. Peptide fibrillization. Angew Chem Int Ed Engl 46 (2007) 8128-8147
-
(2007)
Angew Chem Int Ed Engl
, vol.46
, pp. 8128-8147
-
-
Hamley, I.W.1
-
10
-
-
0027447286
-
Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state
-
Pike C.J., Burdick D., Walencewicz A.J., Glabe C.G., and Cotman C.W. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state. J Neurosci 13 (1993) 1676-1687
-
(1993)
J Neurosci
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
11
-
-
0028172886
-
Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red
-
Lorenzo A., and Yankner B.A. Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. Proc Natl Acad Sci USA 91 (1994) 12243-12247
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12243-12247
-
-
Lorenzo, A.1
Yankner, B.A.2
-
12
-
-
34248185976
-
Differential binding and activation of caspase-3 in cultured hippocampal neurons by assembly forms of A beta 1-42
-
St. John P.A. Differential binding and activation of caspase-3 in cultured hippocampal neurons by assembly forms of A beta 1-42. J Neurosci Res 85 (2007) 1205-1214
-
(2007)
J Neurosci Res
, vol.85
, pp. 1205-1214
-
-
St. John, P.A.1
-
13
-
-
0028207907
-
Amyloid beta peptide induces necrosis rather than apoptosis
-
Behl C., Davis J.B., Klier F.G., and Schubert D. Amyloid beta peptide induces necrosis rather than apoptosis. Brain Res 645 (1994) 253-264
-
(1994)
Brain Res
, vol.645
, pp. 253-264
-
-
Behl, C.1
Davis, J.B.2
Klier, F.G.3
Schubert, D.4
-
14
-
-
0031214063
-
Amyloid β-protein induces necrotic cell death mediated by ICE cascade in PC12 cells
-
Suzuki A. Amyloid β-protein induces necrotic cell death mediated by ICE cascade in PC12 cells. Exp Cell Res 234 (1997) 507-511
-
(1997)
Exp Cell Res
, vol.234
, pp. 507-511
-
-
Suzuki, A.1
-
15
-
-
0027257708
-
Apoptosis is induced by β-amyloid in cultured central nervous system neurons
-
Loo D.T., Copani A., Pike C.J., Whittemore E.R., Walencewicz A.J., and Cotman C.W. Apoptosis is induced by β-amyloid in cultured central nervous system neurons. Proc Natl Acad Sci USA 90 (1993) 7951-7955
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
-
16
-
-
24644453571
-
The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death
-
LeBlanc A.C. The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death. Curr Alzheimer Res 2 (2005) 389-402
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 389-402
-
-
LeBlanc, A.C.1
-
17
-
-
0037106353
-
Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells
-
Lee M., You H.J., Cho S.H., Woo C.H., Yoo M.H., Joe E.H., et al. Implication of the small GTPase Rac1 in the generation of reactive oxygen species in response to beta-amyloid in C6 astroglioma cells. Biochem J 36 (2002) 937-943
-
(2002)
Biochem J
, vol.36
, pp. 937-943
-
-
Lee, M.1
You, H.J.2
Cho, S.H.3
Woo, C.H.4
Yoo, M.H.5
Joe, E.H.6
-
18
-
-
33745268224
-
Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons
-
Deshpande A., Mina E., Glabe C., and Busciglio J. Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons. J Neurosci 26 (2006) 6011-6018
-
(2006)
J Neurosci
, vol.26
, pp. 6011-6018
-
-
Deshpande, A.1
Mina, E.2
Glabe, C.3
Busciglio, J.4
-
19
-
-
0027980901
-
Rapid induction of Alzheimer A beta amyloid formation by zinc
-
Bush A.I., Pettingell W.H., Multhaup G., d Paradis M., Vonsattel J.P., Gusella J.F., et al. Rapid induction of Alzheimer A beta amyloid formation by zinc. Science 265 (1994) 1464-1467
-
(1994)
Science
, vol.265
, pp. 1464-1467
-
-
Bush, A.I.1
Pettingell, W.H.2
Multhaup, G.3
d Paradis, M.4
Vonsattel, J.P.5
Gusella, J.F.6
-
20
-
-
0030066143
-
Zinc-induced aggregation of human and rat β-amyloid peptides in vitro
-
Esler W.P., Stimson E.R., Jennings J.M., Ghilardi J.R., Mantyh P.W., and Maggio J.E. Zinc-induced aggregation of human and rat β-amyloid peptides in vitro. J Neurochem 66 (1996) 723-732
-
(1996)
J Neurochem
, vol.66
, pp. 723-732
-
-
Esler, W.P.1
Stimson, E.R.2
Jennings, J.M.3
Ghilardi, J.R.4
Mantyh, P.W.5
Maggio, J.E.6
-
21
-
-
0032557425
-
Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis
-
Atwood C.S., Moir R.D., Huang X., Scarpa R.C., Bacarra N.M.E., Romano D.M., et al. Dramatic aggregation of Alzheimer Aβ by Cu(II) is induced by conditions representing physiological acidosis. J Biol Chem 273 (1998) 12817-12826
-
(1998)
J Biol Chem
, vol.273
, pp. 12817-12826
-
-
Atwood, C.S.1
Moir, R.D.2
Huang, X.3
Scarpa, R.C.4
Bacarra, N.M.E.5
Romano, D.M.6
-
22
-
-
0037185013
-
Surface-catalyzed amyloid fibril formation
-
Zhu M., Souillac P.O., Ionescu-Zanetti C., Carter S.A., and Fink A.L. Surface-catalyzed amyloid fibril formation. J Biol Chem 277 (2002) 50914-50922
-
(2002)
J Biol Chem
, vol.277
, pp. 50914-50922
-
-
Zhu, M.1
Souillac, P.O.2
Ionescu-Zanetti, C.3
Carter, S.A.4
Fink, A.L.5
-
23
-
-
35748943830
-
Pathways and intermediates of amyloid fibril formation
-
Pellarin R., Guarnera E., and Caflisch A. Pathways and intermediates of amyloid fibril formation. J Mol Biol 374 (2007) 917-924
-
(2007)
J Mol Biol
, vol.374
, pp. 917-924
-
-
Pellarin, R.1
Guarnera, E.2
Caflisch, A.3
-
24
-
-
33747182874
-
Ex situ atomic force microscopy analysis of β-amyloid self-assembly and deposition on a synthetic template
-
Ha C., and Park C.B. Ex situ atomic force microscopy analysis of β-amyloid self-assembly and deposition on a synthetic template. Langmuir 22 (2006) 6977-6985
-
(2006)
Langmuir
, vol.22
, pp. 6977-6985
-
-
Ha, C.1
Park, C.B.2
-
25
-
-
34249041646
-
Metal ions differentially influence the aggregation and deposition of Alzheimer's β-amyloid on a solid template
-
Ha C., Ryu J., and Park C.B. Metal ions differentially influence the aggregation and deposition of Alzheimer's β-amyloid on a solid template. Biochemistry 46 (2007) 6118-6125
-
(2007)
Biochemistry
, vol.46
, pp. 6118-6125
-
-
Ha, C.1
Ryu, J.2
Park, C.B.3
-
26
-
-
33847099068
-
Genotoxic effects in M5 cells and Chinese hamster V79 cells after exposure to 7Li-beam (LET = 60 keV/microm) and correlation of their survival dynamics to nuclear damages and cell death
-
Pathak R., Dey S.K., Sarma A., and Khuda-Bukhsh A.R. Genotoxic effects in M5 cells and Chinese hamster V79 cells after exposure to 7Li-beam (LET = 60 keV/microm) and correlation of their survival dynamics to nuclear damages and cell death. Mutat Res 628 (2007) 56-66
-
(2007)
Mutat Res
, vol.628
, pp. 56-66
-
-
Pathak, R.1
Dey, S.K.2
Sarma, A.3
Khuda-Bukhsh, A.R.4
-
27
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing
-
Carmichael J., DeGraff W.G., Gazdar A.F., Minna J.D., and Mitchell J.B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47 (1987) 936-942
-
(1987)
Cancer Res
, vol.47
, pp. 936-942
-
-
Carmichael, J.1
DeGraff, W.G.2
Gazdar, A.F.3
Minna, J.D.4
Mitchell, J.B.5
-
28
-
-
0036189209
-
Two color, fluorescence-based microplate assay for apoptosis detection
-
Wronski R., Golob N., Grygar E., and Windisch M. Two color, fluorescence-based microplate assay for apoptosis detection. Biotechniques 32 (2002) 666-668
-
(2002)
Biotechniques
, vol.32
, pp. 666-668
-
-
Wronski, R.1
Golob, N.2
Grygar, E.3
Windisch, M.4
-
29
-
-
0037884706
-
A fluorescence microplate assay using yopro-1 to measure apoptosis: application to HL60 cells subjected to oxidative stress
-
Plantin-Carrenard E., Bringuier A., Derappe C., Pichon J., Guillot R., Bernard M., et al. A fluorescence microplate assay using yopro-1 to measure apoptosis: application to HL60 cells subjected to oxidative stress. Cell Biol Toxicol 19 (2003) 121-133
-
(2003)
Cell Biol Toxicol
, vol.19
, pp. 121-133
-
-
Plantin-Carrenard, E.1
Bringuier, A.2
Derappe, C.3
Pichon, J.4
Guillot, R.5
Bernard, M.6
-
30
-
-
19944406829
-
Template-directed self-assembly and growth of insulin amyloid fibrils
-
Ha C., and Park C.B. Template-directed self-assembly and growth of insulin amyloid fibrils. Biotechnol Bioeng 90 (2005) 848-855
-
(2005)
Biotechnol Bioeng
, vol.90
, pp. 848-855
-
-
Ha, C.1
Park, C.B.2
-
31
-
-
0028875851
-
Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis
-
Lizard G., Fournel S., Genestier L., Dhedin N., Chaput C., Flacher M., et al. Kinetics of plasma membrane and mitochondrial alterations in cells undergoing apoptosis. Cytometry 21 (1995) 275-283
-
(1995)
Cytometry
, vol.21
, pp. 275-283
-
-
Lizard, G.1
Fournel, S.2
Genestier, L.3
Dhedin, N.4
Chaput, C.5
Flacher, M.6
-
32
-
-
0034698733
-
Two distinct pathways leading to nuclear apoptosis
-
Susin S.A., Daugas E., Ravagnan L., Samejima K., Zamzami N., Loeffler M., et al. Two distinct pathways leading to nuclear apoptosis. J Exp Med 192 (2000) 571-580
-
(2000)
J Exp Med
, vol.192
, pp. 571-580
-
-
Susin, S.A.1
Daugas, E.2
Ravagnan, L.3
Samejima, K.4
Zamzami, N.5
Loeffler, M.6
-
33
-
-
0032575750
-
Caspases: enemies within
-
Thornberry N.A., and Lazebnik Y. Caspases: enemies within. Science 281 (1998) 1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
34
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner M.O. The biochemistry of apoptosis. Nature 407 (2000) 770-776
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
35
-
-
0035066332
-
Alzheimer's disease: genes, proteins, and therapy
-
Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81 (2001) 741-766
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
36
-
-
0030908095
-
Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time dependent solubility of amyloid proteins
-
Harper J.D., and Lansbury P.T. Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time dependent solubility of amyloid proteins. Annu Rev Biochem 66 (1997) 385-407
-
(1997)
Annu Rev Biochem
, vol.66
, pp. 385-407
-
-
Harper, J.D.1
Lansbury, P.T.2
-
37
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders
-
Caughey B., and Lansbury P.T. Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci 26 (2003) 267-298
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury, P.T.2
-
38
-
-
0026662124
-
β-Amyloid peptide in vitro toxicity: lot-to-lot variability
-
May P.C., Gitter B.D., Waters D.C., Simmons L.K., Becker G.W., Small J.S., et al. β-Amyloid peptide in vitro toxicity: lot-to-lot variability. Neurobiol Aging 13 (1992) 605-607
-
(1992)
Neurobiol Aging
, vol.13
, pp. 605-607
-
-
May, P.C.1
Gitter, B.D.2
Waters, D.C.3
Simmons, L.K.4
Becker, G.W.5
Small, J.S.6
-
39
-
-
0036845354
-
The behavior of polyamino acids reveals an inverse side chain effect in amyloid structure formation
-
Fändrich M., and Dobson C.M. The behavior of polyamino acids reveals an inverse side chain effect in amyloid structure formation. EMBO J 21 (2002) 5682-5690
-
(2002)
EMBO J
, vol.21
, pp. 5682-5690
-
-
Fändrich, M.1
Dobson, C.M.2
-
40
-
-
0347357617
-
Protein folding and misfolding
-
Dobson C.M. Protein folding and misfolding. Nature 426 (2003) 884-890
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
|