Genotoxic effects in M5 cells and Chinese hamster V79 cells after exposure to 7Li-beam (LET = 60 keV/μm) and correlation of their survival dynamics to nuclear damages and cell death

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 628, Issue 1, 2007, Pages 56-66

  Pathak, Rupak ^a   Dey, Subrata Kumar ^a   Sarma, Asiti ^b   Khuda Bukhsh, Anisur Rahman ^c  

^a MAULANA ABUL KALAM AZAD UNIVERSITY OF TECHNOLOGY   (India)

^b INTER UNIVERSITY ACCELERATOR CENTRE   (India)

^c UNIVERSITY OF KALYANI   (India)

Author keywords

7Li beam; Apoptosis; Cell survival; Chromosomal aberrations; High LET radiation; Micronuclei

Indexed keywords

CARCINOGEN; METHYLNITRONITROSOGUANIDINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL NUCLEUS; CELL STRAIN; CELL STRAIN V 79; CELL SURVIVAL; CHINESE HAMSTER; CHROMOSOME ABERRATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DETERMINATION; GENOTOXICITY; LINEAR ENERGY TRANSFER; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RADIOSENSITIVITY;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CRICETINAE; CRICETULUS; DNA DAMAGE; DNA FRAGMENTATION; LASERS; LITHIUM; METAPHASE; MICRONUCLEUS TESTS; RADIOISOTOPES;

CRICETULUS GRISEUS;

EID: 33847099068     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.11.010     Document Type: Article

References (66)

1. 60Co γ-rays and fast neutrons in ataxia talangiectasia lymphocytes. Int. J. Radiat. Biol. 70 (1996) 171-176
2. Ohnishi K., and Ohnishi T. The biological effects of space radiation during long stays in space. Biol. Sci. Space 18 (2004) 201-205
3. Lee R., Nasonova E., and Ritter S. Chromosome aberration yields and apoptosis in human lymphocytes irradiated with Fe-ions of differing LET. Adv. Space Res. 35 (2005) 268-275
4. Rosendahl I.M., Baumstark-Khan C., and Rink H. Mutation induction in mammalian cells by accelerated heavy ions. Adv. Space Res. 36 (2005) 1701-1709
5. Kawata T., Ito H., George K., Wu H., and Cucinotta F.A. Chromosome aberrations induced by high LET radiations. Jpn. Soc. Biol. Sci. Space 18 (2004) 216-223
6. Lett J.T. Damage to cellular DNA from particulate radiation, the efficacy of its processing and the radiosensitivity of mammalian cells. Emphasis on DNA strand breaks and chromatin break. Radiat. Environ. Biophys. 31 (1992) 257-277
7. Ward J.F. Complexcity of damage produced by ionizing radiation. Cold Spring Harb. Symp. Quant. Biol. 65 (2000) 377-382
8. 12C (LET, 295 keV/μm) in M5 cells, a radio resistant cell strain derived from Chinese hamster V79 cells, Int. J. Radiat. Biol., in press.
9. Natarajan A.T., Darroudi F., Mullenders L.H.F., and Meijers M. The nature and repair of DNA lesions that lead to chromosomal aberrations induced by ionizing radiations. Mutat. Res. 160 (1986) 231-236
10. 2 stage of the cell cycle. Mutat. Res. 52 (1978) 137-149
11. Natarajan A.T., and Obe G. Molecular mechanisms involved in the production of chromosomal aberrations, III. Restriction endonucleases. Chromosoma 90 (1984) 120-127
12. Illidge T.M. Radiation induced apoptosis. Clin. Oncol. (R. Coll. Radiol.) 10 (1998) 3-13
13. Langley R.E., Palayoor S.T., Coleman C.N., and Bump E.A. Modifiers of radiation-induced apoptosis. Radiat. Res. 136 (1993) 320-326
14. Radford I.R., and Murphy T.K. Radiation response of mouse lymphoid and myeloid cell lines. Part III. Different signals can lead to apoptosis and may influence sensitivity to killing by DNA double-strand breakage. Int. J. Radiat. Biol. 65 (1994) 229-239
15. 1 V79 cells. Int. J. Radiat. Biol. 69 (1996) 155-166
16. Ritter S., Nasonova E., Gudowska-Novak E., Scholz M., and Kraft G. High-LET-induced chromosome aberrations in V79 cells analysed in first and second post-irradiation metaphases. Int. J. Radiat. Biol. 76 (2000) 149-161
17. Deng W., Morrison D.P., Gale K.L., and Lucas J.N. A comparative study on potential cytogenetic fingerprints for radiation LET in human lymphocytes. Int. J. Radiat. Biol. 76 (2000) 1589-1598
18. Durante M., Bonassi S., George K., and Cucinotta F.A. Risk estimation based on chromosomal aberrations induced by radiation. Radiat. Res. 156 (2001) 662-667
19. Bhattathiri V.N., Bindu L., Remani P., Chandralekha B., Davis C.A., and Nair M.K. Serial cytological assay of micronucleius induction: a new tool to predict human cancer radiosensitivity. Radiother. Oncol. 41 (1996) 139-142
20. Vijayalaxmi K.S., Bisht W.F., Pickard M.L., Meltz J.L., Roti Roti E.G., and Moros. Chromosome damage and micronucleus formation in human blood lymphocytes exposed in vitro to radiofrequency radiation at a cellular telephone frequency (847.74 MHz, CDMA). Radiat. Res. 156 (2001) 430-432
21. Tremp J. Chromosome aberrations and cell survival in irradiated mammalian cells. Radiat. Res. 85 (1981) 554-566
22. Bedford J.S. Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations. Int. J. Radiat. Oncol. Biol. Phys. 21 (1991) 1457-1469
23. Durante M., Grossi G.F., Napolitano M., Pugliese M., and Gialanella G. Chromosome damage induced by high LET α-particles in plateau-phase C3H 10T1/2 cells. Int. J. Radiat. Biol. 62 (1992) 571-580
24. Scholz M., Kraft-Weyrather W., Ritter S., and Kraft G. Cell cycle delays induced by heavy ion irradiation of synchronous mammalian cells. Int. J. Radiat. Biol. 66 (1994) 59-75
25. Kirsch-Volders M., Elhajouji A., Cundari E., and Van Hummelen P. The in vitro micronucleus test: a multi-endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat. Res. 392 (1997) 19-30
26. Levine E.L., Renehan A., Gossiel R., Davidson S.E., Roberts S.A., Chadwick C., Wilks D.P., Potten C.S., Hendry J.H., and Hunter R.D. Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. Radiother. Oncol. 37 (1995) 1-9
27. Jagetia G.C., and Adiga S.K. Correlation between micronuclei induction and cell survival in V79 cells exposed to paclitaxel (Taxol) in conjunction with radiation. Mutat. Res. 377 (1997) 105-113
28. Guo G.Z., Sasai K., Oya N., Shibata T., Shibuya K., and Hiraoka M. A significant correlation between clonogenic radiosensitivity and the simultaneous assessment of micronucleus and apoptotic cell frequencies. Int. J. Radiat. Biol. 75 (1999) 857-864
29. Abend M., Kehe K., Kehe K., Riedel M., and Van Beuningen D. Correlation of micronucleus and apoptosis assays with reproductive cell death can be improved by considering other modes of death. Int. J. Radiat. Biol. 76 (2000) 249-259
30. Liu Z.Z., Huang W.Y., Li X.S., Lin J.S., Cai X.K., Lian K.H., and Zhou H.J. Prediction value of radiosensitivity of hepatocarcinoma cells for apoptosis and micronucleus assay. World J. Gastroenterol. 11 (2005) 7036-7039
31. Roy M., Sengupta S., Bhattacharyya N.P., Dey S.K., and Bhattacharjee S.B. Characterization of methotrexate-resistant clones. Mutat. Res. 291 (1993) 43-51
32. Roy M., Sengupta S., Bhattacharyya N.P., Dey S.K., and Bhattacharjee S.B. Responses of MTX-resistant V79 cells to some DNA damaging agents. Mutat. Res. 285 (1993) 199-207
33. 60Co γ- ray in a cell strain M5, derived from Chinese hamster V79 cells. J. Radio-Anal. Nucl. Chem. 83 1 (2006) 1-11
34. Chaudhuri K., Banerjee R., Pandit B., Mukherjee A., Das S., Sengupta S., Roychoudhury S., and Bhattacharyya N.P. Identification of two differently expressed mitochondrial genes in a methotrexate-resistant Chinese hamster cell strain derived from V79 cells using RNA fingerprinting by arbitrary primed polymerase chain reaction. Radiat. Res. 159 (2003) 98-106
35. Sengupta S., and Bhattacharyya N.P. Possible role of glutathione in resistance to heavy metals and hydrogen peroxide in a radioresistant Chinese hamster V79 cell strain. Indian J. Exp. Biol. 34 (1996) 905-908
36. Puck T.T., and Marcus P.I. A rapid method for viable cell titration and clone production with HeLa cells in tissue culture. The use of X-irradiated cells to supply conditioning factors. Proc. Natl. Acad. Sci. U.S.A. 41 (1955) 432-437
37. Müller W.U., and Streffer C. Micronucleus assay. In: Obe G. (Ed). Advances in Mutagenesis Research, vol. 5 (1994), Springer Verlag, Berlin S. 1-S. 134
38. Giri K., Ghosh U., Bhattacharyya N.P., and Basak S. Caspase 8 mediated apoptotic cell death induced by β-sheet forming polyamine peptides. FEBS Lett. 555 (2003) 380-384
39. Bird R.P., and Burki H.J. Survival of synchronized Chinese hamster cells exposed to radiation of different linear-energy transfer. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 27 (1975) 105-120
40. Belli M., Cherubeni R., Finotto S., Moschini G., Sapora O., Simone G., and Tabocchini M.A. RBE-LET relationship for the survival of V79 cells irradiated with low energy protons. Int. J. Radiat. Biol. 55 (1989) 93-104
41. Napolitano M., Durante M., Grossi G.F., Pugliese M., and Gialanella G. Inactivation of C3H 10T1/2 cells by monoenergetic high LET alpha-particles. Int. J. Radiat. Biol. 61 (1992) 813-820
42. Stenerlow B., Carlsson J., Blomquist E., and Erixon K. Clonogenic cell survival and rejoining of DNA double-strand breaks: comparison between three cell lines after photon or He ion irradiation 65 (1994) 631-639
43. Suzuki M., Kase Y., Kanai T., and Ando K. Correlation between cell death and induction of non-rejoining PCC breaks by carbon-ion beams. Adv. Space Res. 22 (1998) 561-568
44. Bettega D., Calzolari P., Doneda L., Durante M., and Tallone L. Early and delayed reproductive death in human cells exposed to high energy iron ion beams. Adv. Space Res. 35 (2005) 280-285
45. Kranert T., Schneider E., and Kiefer J. Mutation induction in V79 Chinese hamster cells by very heavy ions. Int. J. Radiat. Biol. 58 (1990) 979-987
46. Stoll U., Schmidt A., Schneider E., and Kiefer J. Killing and mutation of hamster V79 cells exposed to accelerated O- and Ne-ions. Radiat. Res. 142 (1995) 288-294
47. Brooks A.L., Newton G.J., Shyr L.J., Seiler F.A., and Scott B.R. The combined effects of alpha-particles and X-rays on cell killing and micronuclei induction in lung epithelial cells. Int. J. Radiat. Biol. 58 (1990) 799-811
48. 213Bi-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage. Eur. J. Nucl. Med. Mol. Imaging 30 (2003) 1357-1364
49. Courdi A., Mari D., Marcie S., Gioanni J., and Chauvel P. Micronucleus induction in 10 human tumor cells after high- and low-dose radiation. Radiother. Oncol. 37 (1995) 117-123
50. Akudugu J.M., Theron T., Serafin A.M., and Bohm L. Influence of DNA double-strand break rejoining on clonogenic survival and micronucleus yield in human cell lines. Int. J. Radiat. Biol. 80 (2004) 93-104
51. Jamali M., and Trott K.R. Persistent increase in the rates of apoptosis and dicentric chromosomes in surviving V79 cells after X-irradiation. Int. J. Radiat. Biol. 70 (1996) 705-709
52. Slavotinek A., McMillan T.J., and Steel C.M. A comparison of micronucleus frequency and radiation survival in lymphoblastoid cell lines. Mutagenesis 8 (1993) 569-575
53. Villa R., Zaffaroni N., Gornati D., Costa A., and Silvestrini R. Lack of correlation between micronucleus formation and radiosensitivity in established and primary cultures of human tumors. Br. J. Cancer 70 (1994) 1112-1117
54. Ritter S., Kraft-Weyrather W., Scholz M., and Kraft G. Induction of chromosome aberrations in mammalian cells after heavy ion exposure. Adv. Space Res. 12 (1992) 119-125
55. Grigorva M., Brand R., Xiao Y., and Natarajan A.T. Frequencies and types of exchanges aberrations induced by X-rays and neutrons in Chinese hamster spleenocytes detected by FISH using chromosome-specific DNA libraries. Int. J. Radiat. Biol. 74 (1998) 297-314
56. George K., Durante M., Wu H., Willingham V., and Cucinotta F.A. In vivo and in vitro measurements of complex-type chromosomal exchanges induced by heavy ions. Adv. Space Res. 31 (2003) 1525-1535
57. -1 C ions. Int. J. Radiat. Biol. 80 (2004) 621-634
58. Savage J.R.K. Classification and relationships of induced chromosomal structural changes. J. Med. Genet. 12 (1975) 103-122
59. Ritter S., Nasonova E., and Gudowska-Novak E. Effect of LET on the yield and quality of chromosomal damage in metaphase cells: a time-course study. Int. J. Radiat. Biol. 78 (2002) 191-202
60. Anderson R.M., Marsden S.J., Wright E.G., Kadhim M.A., Goodhead D.T., and Griffin C.S. Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles. Int. J. Radiat. Biol. 76 (2000) 31-42
61. George K., Durante M., Wu H., Willingham V., Badhwar G., and Cucinotta F.A. Chromosome aberrations in the blood lymphocytes of astronauts after space flight. Radiat. Res. 156 (2001) 731-738
62. Roberts C.J., and Holt P.D. The production of chromosome aberrations in Chinese hamster fibroblasts by gamma and neutron irradiation. Int. J. Radiat. Biol. 41 (1982) 645-656
63. Roberts C.J., and Holt P.D. Induction of chromosome aberrations and cell killing in Syrian hamster fibroblasts by γ-rays, X-rays and fast neutrons. Int. J. Radiat. Biol. 48 (1985) 927-939
64. Takahahashi A., Matsumoto H., Yuki K., Yasumoto J., Kajiwara A., Aoki M., Furusawa Y., Ohnishi K., and Ohnishi T. High LET radiation enhanced apoptosis but not necrosis regardless of p53 status. Int. J. Radiat. Oncol. Biol. Phys. 60 (2004) 591-597
65. McConkey D.J., Orrnius S., and Jondal M. Cellular signaling in programmed cell death (apoptosis). Immunol. Today 11 (1994) 120-121
66. Dunne A.L., Price M.E., Mothersill C., McKeown S.R., Robson T., and Hirst D.G. Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells. Br. J. Cancer 89 (2003) 2277-2283