Conformational changes in a pore-lining helix coupled to cystic fibrosis transmembrane conductance regulator channel gating

Journal of Biological Chemistry

Volumn 283, Issue 8, 2008, Pages 4957-4966

  Beck, Edward J ^a   Yang, Yu ^a   Yaemsiri, Sirin ^a   Raghuram, Viswanathan ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CHEMICAL MODIFICATION; ION EXCHANGE; LININGS;

ATP BINDING CASSETTE TRANSPORTERS; CONFORMATIONAL CHANGE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; GATING MECHANISMS; STRUCTURAL BASIS; SUBSEQUENT HYDROLYSIS; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE SEGMENTS;

CONFORMATIONS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; TRANSMEMBRANE CONDUCTANCE REGULATOR; CFTR PROTEIN, HUMAN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE CONDUCTANCE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; ANIMAL; CYSTIC FIBROSIS; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; XENOPUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; ION CHANNEL GATING; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; XENOPUS;

EID: 41949139811     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702235200     Document Type: Article

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