Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis

Journal of Biological Chemistry

Volumn 283, Issue 8, 2008, Pages 4756-4765

  Petropoulos, Alexandros D ^a   Kouvela, Ekaterini C ^a   Dinos, George P ^a   Kalpaxis, Dimitrios L ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; ANTIBIOTICS; BINDING ENERGY; DRUG INTERACTIONS; ESCHERICHIA COLI; FLOW INTERACTIONS; MAGNESIUM PRINTING PLATES; SUGAR (SUCROSE); SUGARS; TUNNELS;

AFFINITY BINDINGS; BINDING PROCESSES; CONFORMATIONAL CHANGES; DO-MAINS; FOOTPRINTING ANALYSES; IONIC ENVIRONMENTS; LACTONE RINGS; MACROLIDES; POLYAMINES; RIBOSOMAL SUBUNITS; SIDE CHAINS; TIGHT BINDINGS; TYLOSIN; WEAK INTERACTIONS;

BINDING SITES;

ERYTHROMYCIN; MAGNESIUM; NUCLEOSIDE DERIVATIVE; POLYAMINE DERIVATIVE; TRANSFER RNA; TYLOSIN; ANTIINFECTIVE AGENT; BACTERIAL RNA; POLYAMINE; RNA 23S;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG STRUCTURE; EQUILIBRIUM CONSTANT; ESCHERICHIA COLI; HYDROPHILICITY; HYDROPHOBICITY; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RIBOSOME; CHEMISTRY; GENETICS; MUTATION;

ESCHERICHIA COLI;

ANTI-BACTERIAL AGENTS; ERYTHROMYCIN; ESCHERICHIA COLI; HYDROPHOBICITY; KINETICS; MAGNESIUM; MUTATION; POLYAMINES; RIBOSOMES; RNA, BACTERIAL; RNA, RIBOSOMAL, 23S; TYLOSIN;

EID: 41949120352     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708371200     Document Type: Article

References (44)

1. Fernández-Muñoz, R., and Vazquez, D. (1973) J. Antibiot. 26, 107-108
2. Tejedor, F., and Ballesta, J. P. (1986) Biochemistry 25, 7725-7731
3. Katz, L., and Ashley, G. W. (2005) Chem. Rev. 105, 499-527
4. Di Giambattista, M., Engelborghs, Y., Nyssen, E., and Cocito, C. (1987) J. Biol. Chem. 262, 8591-8597
5. Goldman, R. C., Fesik, S. W., and Doran, C. C. (1990) Antimicrob. Agents Chemother. 34, 426-431
6. Dinos, G. P., and Kalpaxis, D. L. (2000) Biochemistry 39, 11621-11628
7. Yan, K., Hunt, E., Berge, J., May, E., Copeland, R. A., and Gontarek, R. R. (2005) Antimicrob. Agents Chemother. 49, 3367-3372
8. Moazed, D., and Noller, H. F. (1987) Biochimie (Paris) 69, 879-884
9. Douthwaite, S., and Aagaard, C. (1993) J. Mol. Biol. 232, 725-731
10. Rodriguez-Fonseca, C., Amils, R., and Garrett, R. A. (1995) J. Mol. Biol. 247, 224-235
11. Hansen, L. H., Mauvais, P., and Douthwaite, S. (1999) Mol. Microbiol. 31, 623-631
12. Poulsen, S. M., Kofoed, C., and Vester, B. (2000) J. Mol. Biol. 304, 471-481
13. Garza-Ramos, G., Xiong, L., Zhong, P., and Mankin, A. (2001) J. Bacteriol. 183, 6898-6907
14. Lovmar, M., Tenson, T., and Ehrenberg, M. (2004) J. Biol. Chem. 279, 53506-53515
15. Berisio, R., Corti, N., Pfister, P., Yonath, A., and Böttger, E. C. (2006) Antimicrob. Agents Chemother. 50, 3816-3823
16. Vester, B., and Douthwaite, S. (2001) Antimicrob. Agents Chemother. 45, 1-12
17. Liu, M., and Douthwaite, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 14658-14663
18. Kirillov, S. V., Porse, B. T., and Garrett, R. A. (1999) RNA (Cold Spring Harbor) 5, 1003-1013
19. Hansen, J. L., Ippolito, J. A., Ban, N., Nissen, P., Moore, P. B., and Steitz, T. A. (2002) Mol. Cell 10, 117-128
20. Champney, W. S. (2001) Curr. Drug Targets Infect. Disord. 1, 19-36
21. Thompson, J., Pratt, C. A., and Dahlberg, A. E. (2004) Antimicrob. Agents Chemother. 48, 4889-4891
22. Schlünzen, F., Zarivach, R., Harms, J., Bashan, A., Tocilj, A., Albrecht, R., Yonath, A., and Franceschi, F. (2001) Nature 413, 814-821
23. Tu, D., Blaha, G., Moore, P., and Steitz, T. (2005) Cell 121, 257-270
24. Wilson, D. N., Harms, J. M., Nierhaus, K. H., Schlünzen, F., and Fucini, P. (2005) Biol. Chem. 386, 1239-1252
25. Vogel, Z., Vogel, T., Zamir, A., and Elson, D. (1971) J. Mol. Biol. 60, 339-346
26. Teraoka, H., and Tanaka, K. (1973) Eur. J. Biochem. 33, 578-583
27. Nanavaty, J., Mortensen, J. E., and Shryock, T. R. (1998) Curr. Microbiol. 36, 212-215
28. Bertho, G., Charbi-Benarous, J., Delaforge, M., and Girault, J. P. (1998) Bioorg. Med. Chem. 6, 209-221
29. Amarantos, I., Xaplanteri, M. A., Choli-Papadopoulou, T., and Kalpaxis, D. L. (2001) Biochemistry 40, 7641-7650
30. Kalpaxis, D. L., Theocharis, D., and Coutsogeorgopoulos, C. (1986) Eur. J. Biochem. 154, 267-271
31. Dinos, G., Wilson, D. N., Teraoka, Y., Szaflarski, W., Fucini, P., Kalpaxis, D. L., and Nierhaus, K. H. (2004) Mol. Cell 13, 113-124
32. Stern, S., Moazed, D., and Noller, H. F. (1988) Methods Enzymol. 164, 481-489
33. Petropoulos, A. D., Xaplanteri, M. A., Dinos, G. P., Wilson, D. N., and Kalpaxis, D. L. (2004) J. Biol. Chem. 279, 26518-26525
34. Vázquez, D. (1979) Mol. Biol. Biochem. Biophys. 30, 1-312
35. Hennelly, S. P., Antoun, A., Ehrenberg, M., Gualerzi, C. O., Knight, W., Lodmell, J. S., and Hill, W. E. (2005) J. Mol. Biol. 346, 1243-1258
36. Morrison, J. F., and Walsh, C. T. (1988) Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201-301
37. Pfister, P., Corti, N., Hobbie, S., Bruell, C., Zarivach, R., Yonath, A., and Böttger, E. C. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 5180-5185
38. Braga, P. C., Culici, M., and Dal Sasso, M. (2004) Int. J. Antimicrob. Agents 24, 56-62
39. Zhong, P., Cao, Z., Hammond, R., Chen, Y., Beyer, J., Shortridge, V. D., Phan, L. Y., Pratt, S., Capobianco, J., Reich, K. A., Flamm, R. K., Or, Y. S., and Katz, L. (1999) Microb. Drug Resist. 5, 183-188
40. Weisblum, B. (1995) Antimicrob. Agents Chemother. 39, 797-805
41. Ehresmann, C., Baudin, F., Mougel, M., Romby, P., Ebel, J.-P., and Ehresmann, B. (1987) Nucleic Acids Res. 15, 9109-9128
42. Xaplanteri, M. A., Petropoulos, A. D., Dinos, G. P., and Kalpaxis, D. L. (2005) Nucleic Acids Res. 33, 2792-2805
43. Pfister, P., Jenni, S., Poehlsgaard, J., Thomas, A., Douthwaite, S., Ban, N., and Böttger, E. C. (2004) J. Mol. Biol. 342, 1569-1581
44. Davydova, N., Streltsov, V., Wilce, M., Liljas, A., and Garber, M. (2002) J. Mol. Biol. 322, 635-644